Publications


2008

Karimi, PN.  2008.  Assessment of drug utilisation and patient knowledge on management of hypertension. Abstract

Hypertension is a common cause of morbidity and mortality. It is a chronic disease and hence requires long-term management. Inadequate control leads to complications that may be fatal if not treated. 5-10 % of the general population is hypertensive. Unfortunately, most victims are not aware of their status and diagnosis is usually accidental especially after complications have set in. Objective The overall objective of this study was to assess patient's knowledge on proper management of hypertension and the types of antihypertensive drugs used at KNH. Aspects covered included types of drugs used, lifestyle issues such as salt intake, exercise, weight loss, use of alcohol and smoking status. Methods The study was conducted at KNH in the department of internal medicine. A cross sectional study design was used and the target population was hypertensive patients. Data was collected using a questionnaire that was filled after interviewing the patients and looking at their hospital records. Fifty patients were selected using systematic random sampling. Data was analyzed using descriptive statistics such as frequency distribution tables, charts and graphs. Statistical techniques used included percentages, figures and mean, standard deviation and confidence intervals. Relationship between variables was evaluated using chi-square. Results All the patients were adults with a mean age of 56.16 years and majority were females (76%). Majority of the respondents were overweight with a mean body mass index of 27.9Kg/m2 • Minority (12.2%) had no formal education and majority (53.2%) was not aware of the normal blood pressure reading. Most patients were unaware of the fact that hypertension can cause complications such as heart failure ( 56%), kidney damage (64%), visual damage (60%) and disturbance of circulation to lower limbs (70%). On average, patients were aware of four out of six non pharmacological measures in the management of hypertension had mixed. All the respondents were either on two (28%), 11 three (50%) or four (22%) antihypertensive drugs. The drugs that were mainly prescribed included Hydrochlorthiazide (58%), Losartan (38%), Amlodipine (34%), Nifedipine (32%), Enalapril (30%) and Atenolol (30%). The association between education level and awareness of complications was statistically significant but that between education level and awareness of non pharmacological management had mixed results. Conclusion A significant proportion of the respondents were not aware of complications and non pharmacological measures of managing hypertension. Antihypertensive drugs were not rationally prescribed. Recommendation Patient education regarding non-pharmacological methods of management and awareness of complications of hypertension should be intensified and rational prescribing should be practiced at KNH.

2005

1998

E.O, PROFWASUNNAAMBROSE.  1998.  Wasunna AE, Wyper DY. Technology for health in the future. World Health Stat Q. 1998;51(1):33-43.. World Health Stat Q. 1998;51(1):33-43.. Abstract
Developments in biogenetics, medical devices, information and communication technologies, and in environmental technologies will have a profound impact on health in the coming decades. However, there are major barriers to the appropriate and effective utilization of current and future technologies, particularly for developing countries. This paper intends to strike a balance between the exciting potential of technologies and the conditions that need to be fulfilled to ensure that technologies are utilized appropriately and effectively. It will emphasize the significance of knowledge associated with technologies, the importance of technology assessment and the need for a broad and comprehensive technology management policy.

1987

E.O, PROFWASUNNAAMBROSE.  1987.  Wasunna AE. Surgical manpower in Africa. Bull Am Coll Surg. 1987 Jun;72(6):18-9.. Bull Am Coll Surg. 1987 Jun;72(6):18-9.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1986

E.O, PROFWASUNNAAMBROSE.  1986.  Wasunna AE. Carcinoma of the oesophagus: alcohol, tobacco and vitamins. East Afr Med J. 1986 Sep;63(9):569-70. No abstract available.. East Afr Med J. 1986 Sep;63(9):569-70.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1978

E.O, PROFWASUNNAAMBROSE.  1978.  Gripenberg U, Saarinen I, Bwibo NO, Oduori ML, Grayburn JA, Awori NW, Wasunna AE, Kinuthia DM. Two true hermaphrodites with XX chromosomes. East Afr Med J. 1978 Aug;55(8):373-9. No abstract available.. East Afr Med J. 1978 Aug;55(8):373-9.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1978.  Calder JF, Wasunna AE. Diverticular disease of the colon in Kenyan Africans. East Afr Med J. 1978 Dec;55(12):579-81. No abstract available.. East Afr Med J. 1978 Dec;55(12):579-81.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1973

E.O, PROFWASUNNAAMBROSE.  1973.  Buxton B, Wasunna AE, Saunders J, Gillespie IE. Effect of truncal vagotomy on the increase in gastric acid secretion induced by small bowel resection in dogs. Digestion. 1973;8(4):293-8. No abstract available.. Digestion. 1973;8(4):293-8.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1973.  Wasunna AE, Wakhisi J, Anabwani GM, Mukuria JW, Roy AD. Experience with gastric acid tests. East Afr Med J. 1973 Aug;50(8):444-8. No abstract available.. East Afr Med J. 1973 Aug;50(8):444-8.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1972

E.O, PROFWASUNNAAMBROSE.  1972.  Buxton B, Wasunna AE, Saunders J, Gillespie IE. Site of the abnormal stimulus of gastric secretion after small bowel exclusion. Gut. 1972 Jul;13(7):539-43. No abstract available.. Gut. 1972 Jul;13(7):539-43.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1972.  Buxton B, Wasunna AE, Bedi BS, Gillespie IE. Role of the jejunum and the ileum in the acid response of dogs to a meal. Gastroenterology. 1972 Aug;63(2):270-2. No abstract available.. Gastroenterology. 1972 Aug;63(2):270-2.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1971

E.O, PROFWASUNNAAMBROSE.  1971.  Wasunna AE, Kennedy F, Gillespie IE, Kay AW. Combined gastric and duodenal ulcers managed by vagotomy and drainage. Lancet. 1971 Apr 10;1(7702):722-3. No abstract available.. Lancet. 1971 Apr 10;1(7702):722-3.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1971.  Buxton BF, Wasunna AE, Gutierrez LV, Bedi BS, Gillespie IE. Role of inhibition by fat in the production of gastric hypersecretion following small-bowel resection. Br J Surg. 1971 Apr;58(4):297. No abstract available.. Br J Surg. 1971 Apr;58(4):297.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1971.  Bedi BS, Debas HT, Wasunna AE, Buxton BF, Gillespie IE. Secretin and cholecystokin-pancreozymin in combination in the inhibition of gastric acid secretion. Gut. 1971 Dec;12(12):968-72. No abstract available.. Gut. 1971 Dec;12(12):968-72.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1971.  Wasunna AE, Buxton BF, Bedi BS, Gillespie IE. Acid responses of denervated fundic (Heidenhain) pouches to meals compared with those to histamine and pentagastrin. Scand J Gastroenterol. 1971;6(5):407-10. No abstract available.. Scand J Gastroenterol. 1971;6(5):407-10.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1970

E.O, PROFWASUNNAAMBROSE.  1970.  Buxton BF, Wasunna AE, Bedi BS, Gillespie IE. The magnitude of the intestinal phase of gastric-acid secretion. Br J Surg. 1970 Nov;57(11):857-8. No abstract available.. Br J Surg. 1970 Nov;57(11):857-8.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1969

E.O, PROFWASUNNAAMBROSE.  1969.  Wasunna AE. A report on two African children with pseudohypertrophic muscular dystrophy. East Afr Med J. 1969 Jul;46(7):437-42. No abstract available.. East Afr Med J. 1969 Jul;46(7):437-42.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.
E.O, PROFWASUNNAAMBROSE.  1969.  Bedi BS, Wasunna AE, Gillespie IE. Effect of bile-salts on antral gastrin release. Br J Surg. 1969 Sep;56(9):695-6. No abstract available. Br J Surg. 1969 Sep;56(9):695-6.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

1968

E.O, PROFWASUNNAAMBROSE.  1968.  Wasunna AE. Asthma as seen at the casualty department, Kenyatta National Hospital, Nairobi. East Afr Med J. 1968 Nov;45(11):701-5. No abstract available.. East Afr Med J. 1968 Nov;45(11):701-5.. Abstract
There is a marked shortage of surgical manpower all over Africa. General surgeons undertake a very wide range of surgical work because of the lack of specialists. Orthopaedic and general surgeons both care for accident injuries. Current training and recruitment programs are inadequate in correcting existing gross manpower deficiencies. The situation is further aggravated by a gross maldistribution of available manpower in favor of large urban centers. In many parts of rural Africa, minor surgical procedures are carried out by suitably trained, non-physician health workers, but facilities and resources for surgery outside urban centers are generally inadequate. The World Health Organization program on essential surgical and anesthetic procedures, which is currently under way in collaboration with the International Federation of Surgical Colleges, the World Federation of Societies of Anesthesiologists, and other professional bodies, should have a significant impact on these urgent needs for basic surgery in rural district hospitals.

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