Mugo NR, Kiehlbauch JA, Nguti R, Meier A, Gichuhi JW, Stamm WE, Cohen CR. Department of Obstetrics and Gynecology, Kenyatta National Hospital, Nairobi, Kenya. Effect of human immunodeficiency virus-1 infection on treatment outcome of acute salpingitis.Obs

Citation:
WANYOIKE DRGICHUHIJOSEPH, WANYOIKE DRGICHUHIJOSEPH. "Mugo NR, Kiehlbauch JA, Nguti R, Meier A, Gichuhi JW, Stamm WE, Cohen CR. Department of Obstetrics and Gynecology, Kenyatta National Hospital, Nairobi, Kenya. Effect of human immunodeficiency virus-1 infection on treatment outcome of acute salpingitis.Obs.". In: PMID: 16582116 [PubMed - indexed for MEDLINE]. Starmat Designers & Allied, Nairobi; 2006.

Abstract:

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OBJECTIVE: To examine the effect of human immunodeficiency virus (HIV)-1 infection on treatment outcome of laparoscopically verified acute salpingitis. METHODS: Women aged 18-40 years with laparoscopically verified acute salpingitis received antibiotic therapy that included cefotetan 2 g intravenously and doxycycline 100 mg orally every 12 hours and laparoscopically guided drainage of tuboovarian abscesses of 4 cm or more. Clinical investigators blinded to HIV-1 serostatus used predetermined clinical criteria, including calculation of a clinical severity score and a standard treatment protocol to assess response to therapy. RESULTS: Of the 140 women with laparoscopically confirmed acute salpingitis, 61 (44%) women had mild, 38 (27%) had moderate, and 41 (29%) had severe disease (ie, pyosalpinx, tuboovarian abscesses, or both). Fifty-three (38%) were HIV-1-infected. Severe disease was more common in HIV-1-infected in comparison with HIV-1-uninfected women (20 [38%] compared with 21 [24%]

Notes:

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