Muchohi, S.N., Kokwaro, G.O., Maitho, T.E., Munenge, R.W., Watkins, W.M., and Edwards, I.G. 2002. Pharmacokinetics of phenytoin following intravenous and intramuscular Administration of fosphentoin and phenytoin sodium in the rabbit. European J. of Drug M

Citation:
ELIAS PROFMAITHOT. "Muchohi, S.N., Kokwaro, G.O., Maitho, T.E., Munenge, R.W., Watkins, W.M., and Edwards, I.G. 2002. Pharmacokinetics of phenytoin following intravenous and intramuscular Administration of fosphentoin and phenytoin sodium in the rabbit. European J. of Drug M.". In: Tropical Animal Health and Production. de Gruyter; 2002.

Abstract:

The efficacies of pyrethrum marc and of albendazole against experimental sheep gastrointestinal nematode infection were compared.  Sheep were infected orally with     10 000 larvae (Haemonchus spp. (60.1%), Oesophagostomum spp. (13.9%), Trichostrongylus spp. (13.2%), Cooperia spp. (8.3%), Nematodirus spp. (3.5%), Strongyloides spp. (0.8%) and Ostertagia spp. (0.2%).  Faecal egg count reduction in albendazole-treated sheep was 100% by day 4 following treatment, compared to 37.03%, 31.3%, 38.9% and 51.8% on days 4,6,8 and 10 in pyrethrum marc-treated sheep.  These reductions were statistically significant on days 8 and 10 post-treatment (p<0.05).  The potential for using pyrethrins for helminth treatment is discussed.

Notes:

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