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2010
John Kinuthia, James N Kiarie, Kiarie JN, Farquhar C, Richardson B, Ruth Nduati, Mbori-Ngacha D, John-Stewart G. "Cofactors for HIV-1 incidence during pregnancy and postpartum period." Curr. HIV Res.. 2010;8(7):510-4. Abstract

to estimate HIV-1 incidence and cofactors for HIV-1 incidence during pregnancy and postpartum.

Graham BJ, RG T, Mulwa JK. "Comparison of Electrical Resistivity 2D Tomography and 1D Profiling to characterize erosion and deposition in the Katonga Valley of SW Uganda.". In: British Society for Geomorphology/British Geomorphological Research Group.; 2010.
PW K, Mbuthia P G, RM W, Njagi L W. "Some pathological changes in Nile Tilapia and Nile Perch from Lake Victoria.". In: Biennial FVM scientific conference. College of Agriculture and Vet. Sciences, University of Nairobi; 2010.2010-some_pathological_changes_in_nile_tilapia.pdf
PW K, Mbuthia P G, RM W, Njagi L W. "Trypanosoma infection in carrier fish of Lake Victoria, Kenya.". In: Biennial FVM scientific conference. College of Agriculture and Vet. Sciences, University of Nairobi; 2010.2010-trypanosoma_infection_in_fish.pdf
Chege F, Day R, T R, A S, Muthomi J, W O, E K, R N, J.G M’E, J J, F O, Mohamed R. "A new partnership in phytosanitary capacity development for protecting agriculture and supporting trade in Africa: The Centre of Phytosanitary Excellence (COPE).". In: 12th KARI Biennial Scientific Conference. KARI Headquarters, Nairobi, Kenya; 2010.
Mwachaka PM, Ranketi SS, Elbusaidy H, Ogeng’o J. "Variations in the anatomy of ansa cervicalis." Folia Morphologica. 2010;69:160-163. AbstractWebsite

Variations in the anatomy of ansa cervicalis

Wambui P, Rodrigues A, Opiyo E. "Licence Plate Recognition System: Localization for Kenya.". In: ICCIR. Kampala Uganda; 2010.
Mwachaka PM, Ranketi SS, Elbusaidy H, Ogeng’o J. "Variations in the anatomy of ansa cervicalis." Folia Morphologica. 2010;69:160-163. AbstractWebsite

Variations in the anatomy of ansa cervicalis

Sueker J, Blazes DL, Johns MC, Blair PJ, Sjoberg PA, Tjaden JA, Montgomery JM, Pavlin JA, Schnabel DC, Eick AA, Tobias S, Quintana M, Vest KG, Burke RL, Lindler LE, Mansfield JL, Erickson RL, Russell KL, Sanchez JL. "Influenza and respiratory disease surveillance: the US military's global laboratory-based network." Influenza Other Respi Viruses. 2010;4:155-61. Abstract

The US Department of Defense influenza surveillance system now spans nearly 500 sites in 75 countries, including active duty US military and dependent populations as well as host-country civilian and military personnel. This system represents a major part of the US Government's contributions to the World Health Organization's Global Influenza Surveillance Network and addresses Presidential Directive NSTC-7 to expand global surveillance, training, research and response to emerging infectious disease threats. Since 2006, the system has expanded significantly in response to rising pandemic influenza concerns. The expanded system has played a critical role in the detection and monitoring of ongoing H5N1 outbreaks worldwide as well as in the initial detection of, and response to, the current (H1N1) 2009 influenza pandemic. This article describes the system, details its contributions and the critical gaps that it is filling, and discusses future plans.

Revay T, Bodzsar N, Mobegi VE, Hanotte O, Hidas A. "Origin of Hungarian indigenous chicken breeds inferred from mitochondrial {DNA} D-loop sequences." Anim. Genet.. 2010;41:548-550. Abstract

In this study, we assessed the maternal origin of six Hungarian indigenous chicken breeds using mitochondrial DNA information. Sequences of Hungarian chickens were compared with the D-loop chicken sequences annotated in the GenBank and to nine previously described reference haplotypes representing the main haplogroups of chicken. The first 530 bases of the D-loop region were sequenced in 74 chickens of nine populations. Eleven haplotypes (HIC1-HIC11) were observed from 17 variable sites. Three sequences (HIC3,HIC8 and HIC9) of our chickens were found as unique to Hungary when searched against the NCBI GenBank database. Hungarian domestic chicken mtDNA sequences could be assigned into three clades and probably two maternal lineages. Results indicated that 86%of the Hungarian haplotypes are related to the reference sequence that likely originated from the Indian subcontinent, while the minor part of our sequences presumably derive from South East Asia, China and Japan.

ODERA BO, Cornish LA, Suss R, Rading GO. "A study of as-cast alloys of the Pt-Cr-V system.". In: Proceedings of the Microscopic Society of Southern Africa Conference. Warmbaths Forever Resorts, South Africa; 2010.
E.E.; E, N.; M, P.; K, Githigia S.M., R. O. "Prevalence of Porcine Cysticercosis and Risk Factors for Taenia solium cysticercosis in Homa Bay District, Kenya.". In: Faculty of Veterinary Medicine, University of Nairobi Biennial Scientific Conference. Na1robi, Kenya; 2010.2010-prevalence_of_porcine_cysticercosis_and_risk_factors_in_homa_bay_kenya.pdf
2011
R.S. O. "Africa."; 2011. Abstract
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Sanchez JL, Johns MC, Burke RL, Vest KG, Fukuda MM, Yoon IK, Lon C, Quintana M, Schnabel DC, Pimentel G, Mansour M, Tobias S, Montgomery JM, Gray GC, Saylors K, Ndip LM, Lewis S, Blair PJ, Sjoberg PA, Kuschner RA, Russell KL, Blazes DL, Witt CJ, Money NN, Gaydos JC, Pavlin JA, Gibbons RV, Jarman RG, Stoner M, Shrestha SK, Owens AB, Iioshi N, Osuna MA, Martin SK, Gordon SW, Bulimo WD, Waitumbi DJ, Assefa B, Tjaden JA, Earhart KC, Kasper MR, Brice GT, Rogers WO, Kochel T, Laguna-Torres VA, Garcia J, Baker W, Wolfe N, Tamoufe U, Djoko CF, Fair JN, Akoachere JF, Feighner B, Hawksworth A, Myers CA, Courtney WG, Macintosh VA, Gibbons T, Macias EA, Grogl M, O'Neil MT, Lyons AG, Houng HS, Rueda L, Mattero A, Sekonde E, Sang R, Sang W, Palys TJ, Jerke KH, Millard M, Erima B, Mimbe D, Byarugaba D, Wabwire-Mangen F, Shiau D, Wells N, Bacon D, Misinzo G, Kulanga C, Haverkamp G, Kohi YM, Brown ML, Klein TA, Meyers M, Schoepp RJ, Norwood DA, Cooper MJ, Maza JP, Reeves WE, Guan J. "Capacity-building efforts by the AFHSC-GEIS program." BMC Public Health. 2011;11 Suppl 2:S4. AbstractWebsite

Capacity-building initiatives related to public health are defined as developing laboratory infrastructure, strengthening host-country disease surveillance initiatives, transferring technical expertise and training personnel. These initiatives represented a major piece of the Armed Forces Health Surveillance Center, Division of Global Emerging Infections Surveillance and Response System (AFHSC-GEIS) contributions to worldwide emerging infectious disease (EID) surveillance and response. Capacity-building initiatives were undertaken with over 80 local and regional Ministries of Health, Agriculture and Defense, as well as other government entities and institutions worldwide. The efforts supported at least 52 national influenza centers and other country-specific influenza, regional and U.S.-based EID reference laboratories (44 civilian, eight military) in 46 countries worldwide. Equally important, reference testing, laboratory infrastructure and equipment support was provided to over 500 field sites in 74 countries worldwide from October 2008 to September 2009. These activities allowed countries to better meet the milestones of implementation of the 2005 International Health Regulations and complemented many initiatives undertaken by other U.S. government agencies, such as the U.S. Department of Health and Human Services, the U.S. Agency for International Development and the U.S. Department of State.

Bulimo W, JL S, MC J, RL B, KG V, MM F, IK Y, C L, M Q, DC S, G P, M M, S T, JM M, GC G, K S, LM N, S L, PJ B, PA S, RA K, KL R, DL B, Group AFHSC-GEISCBW, CJ W, NN M, JC G, JA P, RV G, RG J, M S, SK S, AB O, N I, MA O, SK M, SW G, WD B, DJ W, B A, JA T, KC E, MR K, GT B, WO R, T K, VA L-T, J G, W B, N W, U T, CF D, JN F, JF A, B F, A H, CA M, WG C, VA M, T G, EA M, M G, ' O, AG L, HS H, L R, A M, E S, R S, W S, TJ P, KH J, M M, B E, D M, D B, F W-M, D S, N W, D B, G M, C K, G H, YM K, ML B, TA K, M M, RJ S, DA N, MJ C, JP M, WE R, J G. "Capacity-building efforts by the AFHSC-GEIS program.". 2011. AbstractWebsite
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RAI MRVYASYASHWANT. "The Criminal Liability of Company Directors under the Companies Act in Kenya, 2(5).". In: The Advocate, Journal of the Law Society of Kenya, Nairobi, 20-26.; 2011. Abstract
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RAI MRVYASYASHWANT. "Criminal Liability of Corporations in Malaysia, Current L.J., Kuala Lumpur, 225-31.". In: Journal of Media Law and Practice, London, 11-23.; 2011. Abstract
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RAI MRVYASYASHWANT. ""Doctors and Standard of Medical Care", New Straits Times, Kuala Lumpur.". In: Conference on Materials for Dams.; 2011. Abstract
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Hutchinson MJ, Ambuko J, Nyikal R, Ruto G. Essential Services Package of Support to Improve Productivity of Women Smallholder Farmers in Kenya. University of Nairobi,; 2011. Abstract
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RAI MRVYASYASHWANT. ""Executive Liability for Company Offenses".". In: Executive, Nairobi, 24-26.; 2011. Abstract
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RAI MRVYASYASHWANT. "Freedom of the Press and the Anti-Monopoly Law: Problems of Striking a Proper Balance. 10(1).". In: Journal of Media Law and Practice, London, 11-23.; 2011. Abstract
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Johns MC, Burke RL, Vest KG, Fukuda M, Pavlin JA, Shrestha SK, Schnabel DC, Tobias S, Tjaden JA, Montgomery JM, Faix DJ, Duffy MR, Cooper MJ, Sanchez JL, Blazes DL, Wangchuk S, Dorji T, Gibbons R, Iamsirithaworn S, Richardson J, Buathong R, Jarman R, Yoon IK, Shakya G, Ofula V, Coldren R, Bulimo W, Sang R, Omariba D, Obura B, Mwala D, Kasper M, Brice G, Williams M, Yasuda C, Barthel RV, Pimentel G, Meyers C, Kammerer P, Baynes DE, Metzgar D, Hawksworth A, Blair P, Ellorin M, Coon R, Macintosh V, Burwell K, Macias E, Palys T, Jerke K. "A growing global network's role in outbreak response: AFHSC-GEIS 2008-2009." BMC Public Health. 2011;11 Suppl 2:S3. AbstractWebsite

A cornerstone of effective disease surveillance programs comprises the early identification of infectious threats and the subsequent rapid response to prevent further spread. Effectively identifying, tracking and responding to these threats is often difficult and requires international cooperation due to the rapidity with which diseases cross national borders and spread throughout the global community as a result of travel and migration by humans and animals. From Oct.1, 2008 to Sept. 30, 2009, the United States Department of Defense's (DoD) Armed Forces Health Surveillance Center Global Emerging Infections Surveillance and Response System (AFHSC-GEIS) identified 76 outbreaks in 53 countries. Emerging infectious disease outbreaks were identified by the global network and included a wide spectrum of support activities in collaboration with host country partners, several of which were in direct support of the World Health Organization's (WHO) International Health Regulations (IHR) (2005). The network also supported military forces around the world affected by the novel influenza A/H1N1 pandemic of 2009. With IHR (2005) as the guiding framework for action, the AFHSC-GEIS network of international partners and overseas research laboratories continues to develop into a far-reaching system for identifying, analyzing and responding to emerging disease threats.

Bulimo W, MC J, RL B, KG V, M F, JA P, SK S, DC S, S T, JA T, JM M, DJ F, MR D, MJ C, JL S, DL B, Group AFHSC-GEISORW, S W, T D, R G, S I, J R, R B, R J, IK Y, G S, V O, R C, W B, R S, D O, B O, D M, M K, G B, M W, C Y, RV B, G P, C M, P K, DE B, D M, A H, P B, M E, R C, V M, K B, E M, T P, K J. "A growing global network{'}s role in outbreak response: AFHSC-GEIS 2008-2009.". 2011. AbstractWebsite
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RAI MRVYASYASHWANT. ""Landlords, Tenants and the Law: There is Recourse to the Law".". In: Executive, Nairobi, 19-20.; 2011. Abstract
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RAI MRVYASYASHWANT. ""Of Association and Collusion".". In: Executive, Nairobi, 20-22.; 2011. Abstract
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RAI MRVYASYASHWANT. "Prosecution of Corporations: Procedure in Malaysia and Singapore, Malayan L.J., Singapore, xcii-ci.". In: Journal of Media Law and Practice, London, 11-23.; 2011. Abstract
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Osoro MK, Rathore IV, MANGALA MJ, Mustapha AO. Radioactivity in surface soils around the proposed sites for Titanium Mining Project in Kenya. Citeseer; 2011. AbstractWebsite

Radioactivity measurements were carried out around Maumba and Nguluku villages, two of the proposed sites for titanium mining in the coastal area of Kenya. Samples of surface soils were analyzed using a HPGe gamma spectrometer. The average activity concentrations for …

RAI MRVYASYASHWANT. ""Restraint of Trade - Types of Contract".". In: Executive, Nairobi, 20-22.; 2011. Abstract
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Mwachaka PM, Ranketi SS, Nchafatso OG, Kasyoka BM, Kiboi JG. "Spinal tuberculosis among human immunodeficiency virus-negative patients in a Kenyan tertiary hospital: a 5-year synopsis." The spine journal: official journal of the North American Spine Society. 2011;11:265-269. Abstract

{BACKGROUND} {CONTEXT} Spinal tuberculosis ({TB)} accounts for more than half of all cases of skeletal {TB.} Although Kenya has one of the highest burdens of {TB}, data on spinal {TB} in this country remain scarce. {PURPOSE} To highlight the clinical presentation and management of this condition in our setup. {STUDY} {DESIGN} Retrospective study. {SETTING} Kenyatta National Hospital in Kenya. {PATIENT} {SAMPLE} One hundred twenty-nine patients. {OUTCOME} {MEASURES} Patients' condition after intervention and duration of hospital stay. {METHODS} This study involved review of patients admitted to our hospital between 2004 and 2009 with a diagnosis of spinal {TB.} {RESULTS} The most common presenting complaints were back pain in 100 patients (77.5%) and limb weakness in 94 patients (72.9%), whereas the most frequent physical examination finding was gibbus deformity in 85 patients (65.8%). Most (79 patients, 61.2%) had severe motor and sensory impairment graded as either American Spinal Injury Association ({ASIA)} A or {ASIA} B. Imaging revealed multiple vertebrae disease in 90 patients (79.6%). Of these, the most common was two vertebrae disease in 77 patients (68.1%). All patients were managed using anti-{TB} drugs and analgesics; however, 33 (25.6%) required adjunctive operative management. Mean hospital stay was 53.3 days. Marked clinical improvement was seen in 91 patients (70.0%) within 6 months of treatment. {CONCLUSION} Patients with spinal {TB} in our setting tended to present late and with advanced disease. Therefore, a high index of suspicion should be maintained and appropriate chemotherapy started as early as possible.

Mwachaka PM, Ranketi SS, Nchafatso OG, Kasyoka BM, Kiboi JG. "Spinal tuberculosis among human immunodeficiency virus-negative patients in a {Kenyan} tertiary hospital: a 5-year synopsis." The spine journal: official journal of the North American Spine Society. 2011;11:265-269. Abstract

BACKGROUND CONTEXT Spinal tuberculosis (TB) accounts for more than half of all cases of skeletal TB. Although Kenya has one of the highest burdens of TB, data on spinal TB in this country remain scarce. PURPOSE To highlight the clinical presentation and management of this condition in our setup. STUDY DESIGN Retrospective study. SETTING Kenyatta National Hospital in Kenya. PATIENT SAMPLE One hundred twenty-nine patients. OUTCOME MEASURES Patients' condition after intervention and duration of hospital stay. METHODS This study involved review of patients admitted to our hospital between 2004 and 2009 with a diagnosis of spinal TB. RESULTS The most common presenting complaints were back pain in 100 patients (77.5%) and limb weakness in 94 patients (72.9%), whereas the most frequent physical examination finding was gibbus deformity in 85 patients (65.8%). Most (79 patients, 61.2%) had severe motor and sensory impairment graded as either American Spinal Injury Association (ASIA) A or ASIA B. Imaging revealed multiple vertebrae disease in 90 patients (79.6%). Of these, the most common was two vertebrae disease in 77 patients (68.1%). All patients were managed using anti-TB drugs and analgesics; however, 33 (25.6%) required adjunctive operative management. Mean hospital stay was 53.3 days. Marked clinical improvement was seen in 91 patients (70.0%) within 6 months of treatment. CONCLUSION Patients with spinal TB in our setting tended to present late and with advanced disease. Therefore, a high index of suspicion should be maintained and appropriate chemotherapy started as early as possible.

Padmavathi G, Rajeshwari T, Niranjana Murthy KV. "Study of the variations in the origin & termination of basilar artery." Anatomica Karnataka. 2011;5:54-59. Abstract
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RAI MRVYASYASHWANT. ""The Company as Criminal" (Executive, Nairobi, 6-8).". In: Executive, Nairobi, 24-26.; 2011. Abstract
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RAI MRVYASYASHWANT. ""The Honourable Company Esq.".". In: Executive,Nairobi 29-30, 32.; 2011. Abstract
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RAI MRVYASYASHWANT. ""The Limits of Contractual Restraint".". In: Executive Nairobi, 20-21, 26.; 2011. Abstract
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Njoka E, Riechi A, Obero C, Kemunto W, Muraya D. "Towards Inclusive and Equitable Basic Education System: Kenya’s experience." ADEA Working Document. 2011. Abstract
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Bulimo W, P V, ' N{'}ang, W B, R B, J O, de EP V. "TparvaDB: a database to support Theileria parva vaccine development.". 2011. AbstractWebsite
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Otto JL, Baliga P, Sanchez JL, Johns MC, Gray GC, Grieco J, Lescano AG, Mothershead JL, Wagar EJ, Blazes DL, Achila R, Baker W, Blair P, Brown M, Bulimo W, Byarugaba D, Coldren R, Cooper M, Ducatez M, Espinosa B, Ewings P, Guerrero A, Hawksworth T, Jackson C, Klena JD, Kraus S, Macintosh V, Mansour M, Maupin G, Maza J, Montgomery J, Ndip L, Pavlin J, Quintana M, Richard W, Rosenau D, Saeed T, Sinclair L, Smith I, Smith J, Styles T, Talaat M, Tobias S, Vettori J, Villinski J, Wabwire-Mangen F. "Training initiatives within the AFHSC-Global Emerging Infections Surveillance and Response System: support for IHR (2005)." BMC Public Health. 2011;11 Suppl 2:S5. AbstractWebsite

Training is a key component of building capacity for public health surveillance and response, but has often been difficult to quantify. During fiscal 2009, the Armed Forces Health Surveillance Center, Division of Global Emerging Infections Surveillance and Response System (AFHSC-GEIS) supported 18 partner organizations in conducting 123 training initiatives in 40 countries for 3,130 U.S. military, civilian and host-country personnel. The training assisted with supporting compliance with International Health Regulations, IHR (2005). Training activities in pandemic preparedness, outbreak investigation and response, emerging infectious disease (EID) surveillance and pathogen diagnostic techniques were expanded significantly. By engaging local health and other government officials and civilian institutions, the U.S. military's role as a key stakeholder in global public health has been strengthened and has contributed to EID-related surveillance, research and capacity-building initiatives specified elsewhere in this issue. Public health and emerging infections surveillance training accomplished by AFHSC-GEIS and its Department of Defense (DoD) partners during fiscal 2009 will be tabulated and described.

Bulimo W, JL O, P B, JL S, MC J, GC G, J G, AG L, JL M, EJ W, DL B, Group AFHSC-GEISTW, R A, W B, P B, M B, W B, D B, R C, M C, M D, B E, P E, A G, T H, C J, JD K, S K, V M, M M, G M, J M, J M, L N, J P, M Q, W R, D R, T S, L S, I S, J S, T S, M T, S T, J V, J V, F W-M. "Training initiatives within the AFHSC-Global Emerging Infections Surveillance and Response System: support for IHR (2005).". 2011. AbstractWebsite
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RAI MRVYASYASHWANT. ""White Collar Crime".". In: Executive, Nairobi, 20-22.; 2011. Abstract
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Philipsson J, Rege JEO, Zonabend E. Animal improvement for increased productivity and food availability.; 2011. AbstractWebsite

This module discusses important factors to consider when designing sustainable genetic improvement programmes, especially under tropical conditions. Previous attempts to launch breeding programmes in developing countries have too often failed for several reasons, although there are success stories to learn from as well. Long-term and simple strategies are necessary as is the need to efficiently exploit the potential of indigenous breeds. Increased productivity per animal or area of land used also need to be considered. However, that must be achieved while also considering the variable socio-economic and cultural values of livestock in different societies or regions. Within the module there are links [blue] to web resources and [green] to case studies and other related components of this resource that help illustrate the issues presented.

Rukwaro RW, Ayonga JN, Anunda, Musungu T(2011). Development control frameworks in Kenya.. Nairobi, Kenya: Published report by (AAK/BAF); 2011.
Gloria S. Omosa-Manyonyi, Walter Jaoko OAHOSW, Roselyn Malogo, Jacqueline Nyange PNJN-A, Kirana Bhatt, Bashir Farah MOCSFPPF. ". Reasons for Ineligibility in Phase 1 and 2A HIV Vaccine Clinical Trials at Kenya Aids Vaccine Initiative (KAVI), Kenya." PLoS One. 2011;6(1):e14580.
Rabe M, Price G, Krhoda G, Goodwin R. 2. Climate Change Vulnerability and Infrastructure Investment Assessment and Analysis for Small Scale Water Utilities in the Lake Victoria Basin. Guide Book for water and wastewater utilities. .; 2011. Abstract

The effect of global climate change on the built urban environment, especially installed infrastructure for the
delivery of essential services, will be particularly severe and even more so for developing countries where
resources to deal with anticipated impacts are lacking. Because the delivery of wet services is dependent on
water resources and tends to be an energy intensive operation, water and wastewater utilities will be most
vulnerable to the impacts of climate change. It is therefore imperative that the providers of these services embark on a programme of proactively adapting to the impacts of climate change and mitigating greenhouse gas emissions through improved pumping efficiencies. Because adaptation can take on many forms, utilities must apply logic and rational thinking to this process and prioritize interventions that are most likely to cost effectively address identified
impacts.

Mbuya TO, Sinclair I, Moffat AJ, Reed PAS. "Analysis of fatigue crack initiation and S–N response of model cast aluminium piston alloys." Materials Science and Engineering: A. 2011;528(24):7331-7340. Abstracthttps://doi.org/10.1016/j.msea.2011.06.007

Fatigue crack initiation and S–N fatigue behaviour of hipped model Al7Si–Sr and Al0.7Si piston alloys have been investigated after overaging at 260 °C for 100 h to provide a practical simulation of in-service conditions. The results show that hipping did not affect the S–N behaviour of Al7Si–Sr. This is attributed to the lack of significant change in porosity distribution in this alloy because of its low porosity levels even in the unhipped state. However, hipping profoundly improved the fatigue performance of alloy Al0.7Si due to the significant reduction in porosity. In this investigation, it was observed that porosity was rendered impotent as a fatigue crack initiator in both hipped alloys. Instead, fatigue cracks were observed to originate mainly from intermetallic particles (particularly the Al9FeNi phase) in both alloys and sometimes from oxide particles in Al0.7Si alloy. Fatigue cracking was also frequently observed at intermetallic clusters in hipped Al0.7Si. The observed scatter in fatigue life is discussed in terms of the size of fatigue crack initiating particles and the overall particle size distribution which follows a power law distribution function.

Rintaugu EG, Nteere JS. "Availability and adequacy of sport facilities and equipment in selected secondary schools in Kenya." The Fountain,Journal of Education. 2011;5(1):84-96.
Kihiu J, Rading G, Mutuli S. Boiler, Piping and Pressure Vessel Cross-Bore Design Stresses. Saarbrucken: VDM Publishing; 2011.
Kiama TN, Rita Verhelst, Mbugua PM, Mario Vaneechoutte, Hans Verstraelen, Estambale B, Temmerman M. Characterisation of the vaginal microflora during the menstrual cycle of HIV positive and negative women in a sub-urban population of Kenya.; 2011.
H. JH, R.H. G. "Characteristics of fatal motorcycle crashes into roadside safety barriers in Australia and New Zealand." Accident Analysis and Prevention, Volum. 2011;43(3):652-660.
McKinnon LR, Nyanga B CIKHGBKECAAOAKDPMS, R K. "Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility." J Immunol. . 2011;187(11):6032-42.
Rintaugu EG, Bailasha NK. "Coach-Leadership behaviour exhibited by volleyball Coaches in Africa." International Journal of Current Research. 2011;3(9):135-139.
RIVIELLO B, NEWTON M ACHIENGLETCHFORDLS. "CRITICAL CARE IN RESOURCE LIMITED SETTINGS: LESSONS LEARNED AND FUTURE DIRECTIONS. CRITCAL CARE MED." Critical care medicine. 2011;39(4):860-867.riviello_b.pdf
Gakuya F, Rossi L, Ombui JN, Maingi N, Ogara WO, Soriguer RC, Samer A. "The curse of the prey: Sarcoptes mite molecular analysis reveals potential prey-to-predator parasitic infestation in wild animals from Masai Mara, Kenya." Parasites and Vectors. 2011;4:193-200.
Rao KP, Maitho T, Kamamia EK, Patil AB, Sagre P. "Design and Pre-clinical Studies of Miconazole Soap Strips for Dermal Infections." International Journal of INST Pharmacy and Life Sciences. 2011;1(1):68-76.
Lenze D, Leoncini L, Hummel M, Volinia S, Liu CG, Amato T, Falco DG, Githanga J, Horn H, Nyagol J, Ott G, Palatini J, Pfreundschuh M, Rogena E, Rosenwald A, Siebert R, Croce CM, Stein H. "The different epidemiologic subtypes of Burkitt lymphoma share a homogenous micro RNA profile distinct from diffuse large B-cell lymphoma." Leukemia. 2011:1-8.
Rukwaro R. "Dissemination of Architectural Knowledge among Research, Training and Practice.". 2011. AbstractWebsite

Within the field of architecture, architects and scholars appear to have difficulty making sense of one another’s experience and the relationship between practice and research is often uneven and unclear. In addition, those who identify themselves as scholars of architecture tend to be closed in their academic spheres and vice versa for those who are practitioners. The professionals and scholars seem not to have adequate interchange and reconciliation of the profession. This has not helped much in developing a unifying framework for research and practice of architecture. The scholars and the practicing architect have yet to produce a comprehensive institutional framework capable of directing the profession toward the demonstrable improvement of the architectural practice; training and research. Survey is used as the research design. Questionnaires and interviews were used to collect data from archiects in practice and those in academia, students of architecture and educational administrators. The practicing architects were randomly sampled from the Board of Architects and Quantity Surveying (BORAQS) register. Forty practicing architects were selected. Twenty lecturers and fifty students were interviewed while four administrators were administered questionnaires. Qualitative techniques were used to analyze the responses from the field. This paper has unraveled the minimal relationship between scholars and professionals; the information flow between them and presented the way forward

Subramanian S, H.R P, Birithia, R. S, Muthomi O, P JS, R.D N. "Diversity and distribution of Iris yellow spot virus infecting onions ." Narla, R.D. 2011;101(S172).
R.O N, Kiplagat KW, Kiplagat KW, R.D N, S.J S, J.N K, J.A L. "Early and late harvest agronomic performance and stability of R-free late blight potato genotypes." Crop Improvement. 2011.
R.D N, Muthomi JW, Gachu SM, Nderitu JH, Olubayo FM. "Effect of Intercropping bulb onion and vegetables on purple blotch and downy mildew." Journal of Biological Sciences . 2011;11(1):52-57.effect_of_intercropping_bulb_onion_and_vegetables.pdf
Munoru P, Rintaugu EG. "Effects of yoga training on bilateral strength and Shoulder and hip range motion." International Journal of Current Research. 2011;3(11):467-470.
Ndeda JOH, Rabiu AB, Ngoo LHM, Ouma GO. "Estimation of Climatic Parameters from Solar Indices Using Ground based Data from Kenya, East Africa." Journal of Science and Technology (Ghana). 2011;31(1):131-139. Abstractestimation_of_climatic_parameters_from_solar_indices_using_ground_based_data_from_kenya_east_africa.pdfAfrican Journals Online

The daily meteorological data of relative humidity, maximum, minimum, and average temperatures obtained from five stations of the Kenya Meteorological Department over the period 1986 to 2005 were filtered and reduced to monthly means. Monthly data of solar indices: Sunspot number, F10.7 cm solar radio flux and Mg II core-to-wing ratio covering the same period were employed to model the meteorological variables using the linear multivariate model and applying least square fittings. Validity of the models was tested using Mean Bias Error (MBE) and Root Mean Square Error (RMSE) statistical indicators. The correlations between the observed and predicted values from the models were significant at above 95% level of confidence. The models show the effect of solar forcing on the climatic parameters at different locations in Kenya. Solar forcing of climate is evident in Kenya.
Keywords: modeling, climatic parameters, solar indices, statistical indicators.

S BRS, Pappu HR, Sseruwagi, P. M, R.D N. "First Report of Iris yellow spot virus in Onion in Kenya and Uganda." Plant Disease . 2011;95(1195).
Ouma C, Roca AL, were T, Raballah EO, Oguge NO, Jura WGZO, Ochieng JW, Hanotte O, Georgiadis N. "Genetic structure of hartebeest populations Straddling a transition zone between Morphotypes." J. Basic & Appl. Sci. Res. 2011;1(3):131-149.2011_ouma_et_al_jbasr.pdf
Rintaugu EG, Munayi S, Mwangi I, Ngetich EDK. "The Grand coalition Government in Kenya: A recipe for sports Development." International Journal of Humanities and Social Sciences. 2011;1(18):305-311.
Niels O Verhulst, Phoebe A Mbadi, Gabriella Bukovinszkine Kiss, Wolfgang R Mukabana, Joop JA van Loon, Takken W, Renate C Smallegange. "Improvement of a synthetic lure for Anopheles gambiae using compounds produced by human skin microbiota." Malaria Journal. 2011;10:28.
Inyama HK, Revathi G, Musandu J, Odero T. "The Incidence of Nosocomial Urinary Tract Infections: Kenyatta National Hospital – Intensive Care Unit." Baraton Interdisciplinary Research Journal . 2011;1(2):12-21. Abstractfull_publication_.pdf

Urinary tract infections (UTIs) are the most common nosocomial infections in both acute care settings and long-term care facilities. Each year millions of urethral catheters are put in place in these facilities across the United States. In the acute care settings a vast majority of UTIs occur in patients with temporary urinary catheters. Nosocomial catheter-associated urinary tract infections (NCAUTIs) have been one of the major problems in the Intensive care unit (ICU) and have contributed to the mortality and morbidity of the patients. Efforts to contain the problem have resulted in the introduction of guidelines to reduce the incidence and prevalence of the nosocomial UTI. Such measures have been implemented in the developed world; unfortunately the developing countries have not duplicated the same. This was a descriptive cross-sectional study. Urine samples were collected and analysed in the laboratory for growth of microorganisms to determine the incidence of NCAUTIs. The findings of the study indicate that the Incidence of NCAUTI was determined to be 18% with the common isolated microorganism being Escherichia coli. It recommended that there was need for judicious use of antibiotics to prevent drug resistance and that a procedure and policy on the management of a patient with a urinary catheter should be developed and made available for in the ICU.

De Falco G;, Leoncini L;, Rogena EA. "Infectious agents and lymphoma.". 2011. Abstract

In the past 25 years revelations on the genesis of human cancer have come at an increasing pace. Research on oncogenic infectious agents, especially viruses, has helped us to understand the process of malignant transformation of cells because the cellular events in viral-driven transformation mirror, often brilliantly, basic cellular processes that culminate in cancer, even those not associated with viruses. Infectious agents, especially viruses, account for several of the most common malignancies-up to 20% of all cancers. Some of these cancers are endemic, with a high incidence in certain geographic locations, but sporadic/lower incidence in other parts of the world. Lymphomas arise frequently in association with infectious agents such as Epstein-Barr virus, human immunodeficiency virus, human herpes virus 8, Helicobacter pylori, and hepatitis C virus. In this review, we will focus on the association between infectious agents and lymphomas, with a look at the molecular mechanisms they use to disturb cell regulation and eventually result in cancer.

Rintaugu EG, Mwangi PW, Mwisukha A. "The influence of mass media in Socialization into sports of Kenyan secondary school athletes." International Journal of Current Research. 2011;3(11):471-475.
Dambolenaa JS;, Zuninoa MP;, Lópezb AG;, Rubinsteinc HR;, Zygadloa JA;, Mwangi JW;, Thoithi GN;, Kibwage IO;, Mwalukumbi JM;, Kariuki ST. "Innovative Food Science & Emerging Technologies.". 2011. Abstract

This work investigated the constituents and the efficacy against Fusarium verticillioides infection and fumonisin production of essential oils of Ocimum basilicum L. and Ocimum gratissimum L. from different locations in Kenya.The oil of leaves and flowering tops of O. basilicum from Sagana contained mainly linalool (95%). The flowering tops and leaves from Yatta contained mainly camphor (32.6 and 31.0%, respectively) and linalool (28.2 and 29.3, respectively). Eugenol was the main constituent in the oil of O. gratissimum leaves from both Sagana (95.5%) and Yatta (70.1%). The oil of the flowering tops had significantly less eugenol. The main component of the oil of flowering tops from Yatta was Z-β-ocimene (34.1%). Oil from both species had some antifungal activity. The oils of O. basilicum and O. gratissimum from different locations showed chemical variation, antifungal activity, free radical scavenging capacity and antimycotoxicogenic property. These properties are attributed to the phenolic compound eugenol.Industrial relevanceThis manuscript gives the chemical composition and some biological effects of essential oil of two Ocimum species in Kenya namely Ocimum basilicum L. and Ocimum gratissimum L. The work reveals that there are chemovarieties of these plants in different locations in the country. Of significance is the presence of very high amounts of linalool in one chemovariety of O. basilicum while geranial and neral are major in another. The third variety contains almost equal amounts of camphor and linalool. The first two containing high quantities of linalool, geranial and neral could be cultivated after agronomic studies to provide essential oils useful in perfumery, soap or food industry while that containing camphor and linalool may find use in medicine.Proper seed selection and good agricultural practice for O. gratissimum containing high amount of eugenol could serve as good substitute for cloves which grows best only in a few islands in East Africa. Clove oil due to its high eugenol content has many biological activities including those demonstrated in the present work, and many applications in medicine and commercial world.There is need for more research on these plants especially on cultivation and commercial exploitation of the herbs.

Newton MW;, Achieng L;, Letchford S;, Riviello ED. "Intensive care in poor-resource settings: Solutions are in the hands at home Reply.". 2011.
Refat MS;, Saad HA;, Adam AM. "Intermolecular hydrogen bond complexes by in situ charge transfer complexation of o-tolidine with picric and chloranilic acids.". 2011. Abstract

A two new charge transfer complexes formed from the interactions between o-tolidine (o-TOL) and picric (PA) or chloranilic (CA) acids, with the compositions, [(o-TOL)(PA)(2)] and [(o-TOL)(CA)(2)] have been prepared. The (13)C NMR, (1)H NMR, (1)H-Cosy, and IR show that the charge-transfer chelation occurs via the formation of chain structures O-H⋯N intermolecular hydrogen bond between 2NH(2) groups of o-TOL molecule and OH group in each PA or CA units. Photometric titration measurements concerning the two reactions in methanol were performed and the measurements show that the donor-acceptor molar ratio was found to be 1:2 using the modified Benesi-Hildebrand equation. The spectroscopic data were discussed in terms of formation constant, molar extinction coefficient, oscillator strength, dipole moment, standard free energy, and ionization potential. Thermal behavior of both charge transfer complexes showed that the complexes were more stable than their parents. The thermodynamic parameters were estimated from the differential thermogravimetric curves. The results indicated that the formation of molecular charge transfer complexes is spontaneous and endothermic.

Rintaugu EG, Mwisukha A, Mundia F. "International Journal of Humanities and Social Sciences." International Journal of Humanities and Social Sciences. 2011;1(17):162-167.
Nyongesa FW, Aduda BO, Soboyejo WO, Obwoya SK, Rahbar N, Zimba J. "An Investigation of Thermal Shock in Porous Clay Ceramics." ISRN Mechanical Engineering. 2011;DOI 10.5402/2011/816853(816853).thermal_shock_in_porous_clay_ceramics_2011.pdf
F.W. Nyongesa, Rahbar N, Obwoya SK, Zimba J, Aduda BO, Soboyejo WO. "An Investigation of Thermal Shock in Porous Clay Ceramics." International Scholarly Research Network. 2011:9. Abstract

The thermal shock resistance of porous ceramic materials is often characterized by the Hasselman parameters. However, in other
scenarios, the room-temperature residual strengths after thermal shock are also used to quantify the damage due to thermal shock.
This paper attempts to link the measured residual strengths to the dominant crack features that are introduced due to thermalshock in porous clay ceramics produced by the sintering of clay powders with well-controlled size ranges. Residual strength estimates from bend tests are compared with fracture mechanics predictions. The implications of the residual strength results are then discussed for the characterization of damage due to thermal shock.

Ujiji OA;, Rubenson B;, Ilako F;, Marrone G;, Wamalwa D;, Wangalwa G;, Ekström AM. "Is 'Opt-Out HIV Testing' a real option among pregnant women in rural districts in Kenya?". 2011. Abstract

BACKGROUND: An 'opt-out' policy of routine HIV counseling and testing (HCT) is being implemented across sub-Saharan Africa to expand prevention of mother-to-child transmission (PMTCT). Although the underlying assumption is that pregnant women in rural Africa are able to voluntarily consent to HIV testing, little is known about the reality and whether 'opt-out' HCT leads to higher completion rates of PMTCT. Factors associated with consent to HIV testing under the 'opt-out' approach were investigated through a large cross-sectional study in Kenya. METHODS: Observations during HIV pre-test information sessions were followed by a cross-sectional survey of 900 pregnant women in three public district hospitals carrying out PMTCT in the Busia district. Women on their first antenatal care (ANC) visit during the current pregnancy were interviewed after giving blood for HIV testing but before learning their test results. Descriptive statistics and multivariate regression analysis were performed. RESULTS: Of the 900 women participating, 97% tested for HIV. Lack of testing kits was the only reason for women not being tested, i.e. nobody declined HIV testing. Despite the fact that 96% had more than four earlier pregnancies and 37% had been tested for HIV at ANC previously, only 17% of the women surveyed knew that testing was optional. Only 20% of those surveyed felt they could make an informed decision to decline HIV testing. Making an informed decision to decline HIV testing was associated with knowing that testing was optional (OR = 5.44, 95%CI 3.44-8.59), not having a stable relationship with the child's father (OR = 1.76, 95%CI 1.02-3.03), and not having discussed HIV testing with a partner before the ANC visit (OR = 2.64 95%CI 1.79-3.86). CONCLUSION: High coverage of HIV testing appears to be achieved at the cost of pregnant women not understanding that testing is optional. Good quality HIV pre-test information is central to ensure that pregnant women understand and accept the reasons for testing and will thus come back to collect their test results, an important prerequisite for completing PMTCT for those who test HIV-positive.

MOULTON, J.E., Movassaghi, M., Jamison, J.L., Lobo, C., Lobo, C., Witbeck, W., Gikonyo, K., Gaynor, J., Rothschild, L.J., Mwaura F, and Duboise SM. "Isolation and Initial Study of Ø1M3-16, a Bacteriophage Infecting an Alkaliphilic Nitrincola sp Isolate from Lake Magadi, a Soda Lake in Kenya’s Great Rift Valley." Microscopy & Microanalysis,. 2011;17, S2, :350-351b.
Susan S Imbahale, Krijn P Paaijmans, Wolfgang R Mukabana, Ron van Lammeren, Githeko AK, Takken W. "A longitudinal study on Anopheles mosquito larval abundance in distinct geographical and environmental settings in western Kenya. ." Malaria Journal. 2011;10:81.
Rayya. "Mama Mkwe.". In: Kopo la Uji na Hadithi Nyingine. Nairobi: East African Educational Publishers; 2011.
Mutebi MC, Saidi H, Raja AJ. "Mentoring the modern African Surgeon- a call to arms!" Annals of African Surgery.. 2011;7.Website
K MJ, M.W.K M, Muturi PW, R.W N, Kiarie N, E.M A, J.K M. "Morphological differences among susceptible and resistant sweet potato varieties.". In: aGRO 2011 Biennial Conference.; 2011.
Rintaugu EG, Nteere JS. "Motivational orientations in sport: A study of college athletes in Kenya." International Journal of Current Research. 2011;3(8):168-171.
C.K. M, R.W M. "New use of Indomethacin." East Cent. Afri. J. Pharm. Sci.. 2011;14(1):13-15.
Kwaako OA, Kimani K, Ilako DR, Akafo S, Ekem I, Rodrigues O, Laryea CE, Nentwich MM. "Ocular Manifestations of Sickle Cell Disease at Korle bu Hospital, Accra, Ghana." European Journal of Ophthalmology. 2011;21(4):484-489.
Slyker JA, John-Stewart GC, Dong T, Lohman-Payne B, Reilly M, Atzberger A, Taylor S, Maleche-Obimbo E, Mbori-Ngacha D, Rowland-J. "Phenotypic Characterization of HIV-Specific CD8+ T Cells during Early and Chronic Infant HIV-1 Infection." BMC Infect Dis. 2011; 11: 259. Published online 2011 September 30. doi: 10.1186/1471-2334-11-259. 2011. Abstractphenotypic_characterization_of_hiv-specific_cd8.pdf

Abstract
Although CD8+ T cells play an important role in the containment of adult HIV-1 replication, their role in infant HIV-1
infection is not as well understood. Impaired HIV-specific CD8+ T cell responses may underlie the persistently high viral loads
observed in infants. We examined the frequency and phenotype of infant HIV-specific CD8+ T cells in 7 HIV-infected
antiretroviral therapy-naı¨ve infants during the first 2 years of life, using class I HLA tetramers and IFN-c-ELISPOT. The
frequency (0.088–3.9% of CD3+CD8+ cells) and phenotype (CD27+CD282, CD45RA+/2, CD57+/2, HLA-DR+, CD95+) of infant
HIV-specific CD8+ T cells were similar to reports in adults undergoing early infection. Unlike adults, at 23–24 months postinfection
a high frequency of HIV-specific CD8+ T cells expressed HLA-DR (mean 80%, range 68–85%) and CD95 (mean 88%,
range 79–96%), suggesting sustained activation and vulnerability to apoptosis. Despite comparable expansion of HIVspecific
CD8+ T cells of a similar phenotype to adults during early infection, infant T cells failed to contain HIV-1 replication,
and remained persistently activated and vulnerable to apoptosis during chronic infection.

Rayya. "Picha ya Hadaa.". In: Sina Zaidi na Hadithi Nyingine. Nairobi: Target Publishers; 2011.
Rege JEO, Marshall K, Notenbaert A;, Ojango JMK, Okeyo AM. "Pro-poor animal improvement and breeding — What can science do?". 2011. Abstract

Livestock provide a wide variety of goods and services that generate income and support the livelihoods of millions of poor people in the developing world. Natural and human selections have shaped existing livestock genotypes throughout the estimated 12,000 year history since the first animal domestication. The result, in many production systems in the developing world, is a livestock genotype adapted to its environment and capable of meeting the needs of smallholder farmers. However, this adaptation is unlikely to be optimal and the rapid changes currently affecting the livestock sector, including policy and market changes, movements of germplasm frequently involving the importation of exotic breeds, and the increasing impacts of climate change are affecting the livestock genotype-environment optimum. This is challenging livestock production systems of smallholder farmers. Current challenges include: high rates of loss of the diversity in livestock populations, rapid transformation in smallholder production systems requiring significant changes in genotypes and their management; increased demand for quality and safe foods; increased market competition in a globalizing economy; increased need for complex partnership arrangements in the ever-changing livestock commodity chain; and lack of adaptive capacity to respond to the rapid system changes. Underlying all these is the general lack of strategies for genetic improvement of livestock in smallholder systems and poor livestock infrastructure in developing countries. Opportunities include increased demand for livestock products — and hence potential market opportunities, and new technologies with potential to leap-frog breeding progress in developing countries. This paper analyses options for pro-poor livestock improvement in developing countries, with particular emphasis on the potential role that science – both old and new – will have, from understanding the social underpinnings to innovative technical solutions. It concludes that one of the highest priority interventions for the smallholder systems is the development of innovative approaches for the strategic use of appropriate genotypes from the available range of global breed resources. The analysis strongly suggests that the highest priority ‘breeding intervention’ should be the provision of appropriate genotypes in a sustainable manner, underpinned by a good understanding of what breed resources exist that have demonstrated potential, where else they could be used, and how they would be delivered to smallholders. Efforts to improve/refine breeding skills of smallholders should proceed in parallel. Institutional arrangements and enabling policies are critical for the success in identifying and applying appropriate genetic technologies, improving access to input services and facilitating access to markets in order to translate productivity gains into incomes

Masese LN, Graham SM, Gitau R, Peshu N, Jaoko W, Ndinya-Achola JO, Mandaliya K, Richardson BA, Overbaugh J, McClelland SR. "A prospective study of vaginal trichomoniasis and HIV-1 shedding in women on antiretroviral therapy.". 2011. Abstract

Trichomonas vaginalis has been associated with increased vaginal HIV-1 RNA shedding in antiretroviral therapy (ART)-naïve women. The effect of trichomoniasis on vaginal HIV-1 shedding in ART-treated women has not been characterized. We tested the hypothesis that T. vaginalis infection would increase vaginal HIV-1 RNA shedding in women on ART, and that successful treatment would reduce vaginal HIV-1 RNA level

Bailasha NK, Rintaugu EG, Toriola AL. "Psycho-social attribute of elite African Women Volleyball players." African journal for Physical, Health Education, Recreation, sports andDance(AJPHERD). 2011;17(3):535-546.
Chung MH, Richardson BA, Tapia K, Benki-Nugent S, Kiarie JN, Simoni JM, Overbaugh J, Attwa M, John-Stewart GC. "A Randomized Controlled Trial Comparing the Effects of Counseling and Alarm Device on HAART Adherence and Virologic Outcomes.". 2011. Abstract

Behavioral interventions that promote adherence to antiretroviral medications may decrease HIV treatment failure. Antiretroviral treatment programs in sub-Saharan Africa confront increasing financial constraints to provide comprehensive HIV care, which include adherence interventions. This study compared the impact of counseling and use of an alarm device on adherence and biological outcomes in a resource-limited setting. Methods and Findings A randomized controlled, factorial designed trial was conducted in Nairobi, Kenya. Antiretroviral-naïve individuals initiating free highly active antiretroviral therapy (HAART) in the form of fixed-dose combination pills (d4T, 3TC, and nevirapine) were randomized to one of four arms: counseling (three counseling sessions around HAART initiation), alarm (pocket electronic pill reminder carried for 6 months), counseling plus alarm, and neither counseling nor alarm. Participants were followed for 18 months after HAART initiation. Primary study endpoints included plasma HIV-1 RNA and CD4 count every 6 months, mortality, and adherence measured by monthly pill count. Between May 2006 and September 2008, 400 individuals were enrolled, 362 initiated HAART, and 310 completed follow-up. Participants who received counseling were 29% less likely to have monthly adherence <80% (hazard ratio [HR]=0.71; 95% confidence interval [CI] 0.49–1.01; p=0.055) and 59% less likely to experience viral failure (HIV-1 RNA ≥5,000 copies/ml) (HR 0.41; 95% CI 0.21–0.81; p=0.01) compared to those who received no counseling. There was no significant impact of using an alarm on poor adherence (HR 0.93; 95% CI 0.65–1.32; p=0.7) or viral failure (HR 0.99; 95% CI 0.53–1.84; p=1.0) compared to those who did not use an alarm. Neither counseling nor alarm was significantly associated with mortality or rate of immune reconstitution. Conclusions Intensive early adherence counseling at HAART initiation resulted in sustained, significant impact on adherence and virologic treatment failure during 18-month follow-up, while use of an alarm device had no effect. As antiretroviral treatment clinics expand to meet an increasing demand for HIV care in sub-Saharan Africa, adherence counseling should be implemented to decrease the development of treatment failure and spread of resistant HIV.

Plummer FA, Moses S, Willbond B, Rao PJVR, Ngugi EN, Nagelkerke NJD, Jha P. "Reducing HIV Transmission in Developing Countries.". 2011. Abstract

Although the global response to the HIV/AIDS epidemic in the developing world has, in general, been inadequate, there are key interventions which have been proven to be effective in reducing the incidence of HIV and relevant risky behaviors. We review and analyze these interventions according to three criteria: importance to HIV transmission, amenability to change, and cost-effectiveness.

Chiao C, Morisky DE, Rosenberg R, Ksobiech K, Malow R, Ngugi EN. "The relationship between HIV/Sexuaily Transmitted Infection risk and alcohol use during commercial sex episodes: results from the study of female commercial sex workers in the Philippines.". 2011. Abstract

The results of this study will be particularly important in designing more responsive interventions for alcohol-related behaviour towards better control of HIV and sexually transmitted infections. This interesting finding involved a large sample size (1114 female commercial sex workers). geographical distribution (four provinces in the Philippines) and duration which were large enough for generalization. The authors re-demonstrate the association between alcohol use amongst female sex-workers and clients and HIV/sexually transmitted disease risk.

Ngugi RW, Mohapatra S, Ratha D. "Remittances market in Kenya.". In: Remittance Markets in Africa. The World Bank; 2011.
Ngugi RW, Sennoga E, Mohapatra S, Ratha D. "Remittances market in Uganda.". In: Remittance Markets in Africa. The World Bank; 2011.
Rintaugu EG, Mwisukha A. "Retirement from competitive sport: The experiences of Kenyan soccer players." Current Research Journal of Social Sciences. 2011;3(6):477-482.
Verhulst N., Mukabana W.R., Takken W, R.mallegange. "Skin microbiota volatiles as odour baits for the malaria mosquito Anopheles gambiae." Entomologia Experimentalis et applicata. 2011;139:170-179.
ODERA BO, Cornish LA, Rading GO, Papo MJ. "Solidification projection of the Pt-Al-V system at the Pt-rich corner."; 2011.
phillip mwachaka, Ranketi S, G O, kasyoka B, J.G KIBOI. "Spinal tuberculosis among human immunodeficiency virus-negative patients in a Kenyan tertiary hospital: a 5-year synopsis." THE SPINE JOURNAL. 2011;4(APRIL11):265-269.
Addis Teshome, Raina SK, Vollrath F, Kabaru JM, Onyari J, Nguku EK. "Study on Weight Loss and moisture Regain of Silk Cocoon Shells and Degummed Fibers from African Wild Silkmoths." Journal of Entomology. 2011;8(5):450-458. AbstractWebsite

Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} A study was conducted to determine weight loss and moisture regain properties of silk cocoon shells, shell layers and degummed fibers of the four African wild silkmoths Anaphe panda, Argema mimosae, Epiphora bauhiniae and Gonometa postica and compare "with the industry standard mulberry silkmoth, Bombyx mori. No. significant difference was observed between the moisture regain of the wild silk fibers after degumming. However, there were significant differences in weight loss and moisture regain between cocoon shells as well as shell layers. E. bauhiniae had the lowest weight loss and moisture regain of 23.19 and 5.64%, respectively while G. postica had the highest weight loss and moisture regain, 56.84 and 9.05%, respectively. The SEM micrographs also showed the presence of remnant sericin gum on the fibers surface. In both A. panda and E. bauhiniae, the outer shell layers had the lowest moisture regain and highest weight loss while the inner layer of E. bauhiniae and middle layer of A. panda lost the least weight. The physical structure and chemical composition ofthe cocoon shells and fibers contribute towards the variation in the moisture regain and weight loss and these features may have commercial implications due to their direct effect on the resulting fabric

Teshome A, Raina SK, Vollrath F, Kabaru JM, Onyari J, EK N, Nguku. "Study on weight loss and moisture regain of Silk Cocoon shells and Degummed Fibers from African Wild Silkmoths." Journal of Entomology . 2011;8(5):450-458.
Teshome A, Raina SK, Vollrath F, Kabaru JM, Onyari J, Nguku EK. "Study on weight loss and moisture regain of silk cocoon shells and degummed fibers from African wild silks." Journal of Entomology. 2011;8(5):450-458.
Kosgei RJ, Ndavi MP, Ong’ech JO, Abuya JM, Siika AM, Wools-Kaloustian K, Mabeya H, Fojo T, Mwangi A, Reid T, Edginton ME, Carter JE. "Symptom screening: diagnostic usefulness to detect pulmonary tuberculosis in HIV-infected pregnant women in Kenya." Public Health Action . 2011;1(2):30-33.symptom_screening_diagnostic_usefulness_to_detect_pulmonary_tuberculosis_in_hiv-infected_pregnant_women_in_kenya.pdf
Michira IN, Richard A, Priscilla B, Immanuel I. "Synthesis, characterization and Application of Sulfonated polyaniline in Construction of a biosensor for Diazinon." International Journal of Polymeric Materials. 2011;60:469-489. AbstractWebsite

A series of sulfonated polyaniline=derivatized polyaniline nanocomposites was chemically synthesized in the presence of anthracene and naphthalene sulfonic acids. UV-vis and FTIR results indicated the emergence of new bands at 420 and 700nm and1100cm-1 in their spectra, respectively, meaning the dopant/polymer intercalations involved electronic interactions between dopant/polymer sub-lattices. The electroactive
composites displayed moderately fast electrode kinetics. A composite-based biosensor for hydrogen peroxide reached a steady state current of 9.2 and 5.3 mA, and when fine-tuned for diazinon detection gave % inhibitions to be 41 and 81% for thepolyaniline and poly-o-methoxyaniline biosensors, respectively.

Otieno, David J, Hubbard L, Ruto E. "Technical efficiency and technology gaps in beef cattle production systems in Kenya:A stochastic metafrontier analysis.". 2011. Abstract

In this study the stochastic metafrontier method is used to investigate technical efficiency and technology gaps across three main beef cattle production systems in Kenya. Results show that there is significant inefficiency in nomadic and agro-pastoral systems. Further, in contrast with ranches,these two systems were found to have lower technology gap ratios. The average pooled technical efficiency was estimated to be 0.69, which suggests that there is considerable scope to improve beef production in Kenya.

John Kinuthia, James N Kiarie, Farquhar C, Ruth Nduati, Mbori-Ngacha D, and John-Stewart G. "Uptake of prevention of mother to child transmission interventions in Kenya: health systems are more influential than stigma." Journal of the International AIDS Society 2011, 14:61. 2011. Abstract

Abstract
Background: We set out to determine the relative roles of stigma versus health systems in non-uptake of
prevention of mother to child transmission (PMTCT) of HIV-1 interventions: we conducted cross-sectional
assessment of all consenting mothers accompanying infants for six-week immunizations.
Methods: Between September 2008 and March 2009, mothers at six maternal and child health clinics in Kenya’s
Nairobi and Nyanza provinces were interviewed regarding PMTCT intervention uptake during recent pregnancy.
Stigma was ascertained using a previously published standardized questionnaire and infant HIV-1 status
determined by HIV-1 polymerase chain reaction.
Results: Among 2663 mothers, 2453 (92.1%) reported antenatal HIV-1 testing. Untested mothers were more likely
to have less than secondary education (85.2% vs. 74.9%, p = 0.001), be from Nyanza (47.1% vs. 32.2%, p < 0.001)
and have lower socio-economic status. Among 318 HIV-1-infected mothers, 90% reported use of maternal or infant
antiretrovirals. Facility delivery was less common among HIV-1-infected mothers (69% vs. 76%, p = 0.009) and was
associated with antiretroviral use (p < 0.001). Although internal or external stigma indicators were reported by
between 12% and 59% of women, stigma was not associated with lower HIV-1 testing or infant HIV-1 infection
rates; internal stigma was associated with modestly decreased antiretroviral uptake. Health system factors
contributed to about 60% of non-testing among mothers who attended antenatal clinics and to missed
opportunities in offering antiretrovirals and utilization of facility delivery. Eight percent of six-week-old HIV-1-
exposed infants were HIV-1 infected.
Conclusions: Antenatal HIV-1 testing and antiretroviral uptake was high (both more than 90%) and infant HIV-1
infection risk was low, reflecting high PMTCT coverage. Investment in health systems to deliver HIV-1 testing and
antiretrovirals can effectively prevent infant HIV-1 infection despite substantial HIV-1 stigma.
Keywords: mother-to-child HIV transmission, HIV/AIDS, Health system, testing, antiretrovirals, facility delivery

Faria PJ, Kavembe GD, Jung'a JO, Kimwele CN, Estes LD, Reilo PR, Mwangi AG, Bruford MW. "The use of non-invasive molecular techniques to confirm the presence of mountain bongo Tragelaphus eurycerus isaaci populations in Kenya and preliminary inference of their mitochondrial genetic variation." Conserv Genet. 2011;10. AbstractWebsite

The mountain bongo antelope Tragelaphus eurycerus isaaci has rapidly declined in recent decades, due to a combination of hunting, habitat degradation and disease. Endemic to Kenya, mountain bongo populations have shrunk to approximately 100 individuals now mainly confined to the Aberdares mountain ranges. Indirect observation of bongo signs (e.g. tracks, dung) can be misleading, thus methods to ensure reliable species identification, such as DNA-based techniques, are necessary to effectively study and monitor this species. We assessed bongo presence in four mountain habitats in Kenya (Mount Kenya National Park, Aberdare National Park, Eburu and Mau forests) and carried out a preliminary analysis of genetic variation by examining 466 bp of the first domain of the mtDNA control region using DNA extracted from faecal samples. Of the 201 dung samples collected in the field, 102 samples were molecularly identified as bongo, 97 as waterbuck, one as African buffalo and one as Aders’ duiker. Overall species-identification accuracy by experienced trackers was 64%, with very high error of commission when identifying bongo sign (37%), and high error of omission for waterbuck sign (82%), suggesting that the two species’ signs are easily confused. Despite high variation in the mtDNA control region in most antelope species, our results suggest low genetic variation in mountain bongo as only two haplotypes were detected in 102 samples analyzed. In contrast, the analysis of 63 waterbuck samples from the same sites revealed 21 haplotypes. Nevertheless, further examination using nuclear DNA markers (e.g. microsatellites) in a multi-locus approach is still required, especially because the use of mitochondrial DNA can result in population overestimation as distinct dung samples can potentially be originated from the same individual.

Karimurio J, Rono H, Richard L, Mutuku M, Keeffe J. "What is the appropriate age range of individuals to be included in a survey to estimate the prevalence of trachomatous trichiasis?" Br J Ophthalmol. 2011;95:1058-1060. Abstract

Introduction: A survey to determine the prevalence of trachomatous trichiasis (TT) requires a large sample size and the recommended participant age is >15 years. This study sought to establish the appropriate age range of individuals to be included in TT surveys.
Methods: Data from six previous surveys of adults >15 years old were reanalysed.
Results: Reanalysis indicated that 69.6-93.3% (average
87.0%) of untreated TT occurred in those aged 40+ years and 52.2e86.7% (average 73.1%) in those aged 50+ years (age >50 years is used in rapid assessment of avoidable blindness). Age >40 years was adopted in a TT survey conducted in Turkana district because it allowed a smaller sample size than age >15 years.
Conclusions: The estimated backlog of untreated TT in people aged >40 years old in Turkana was 5932 and the overall TT backlog was likely to be 6358-8523. These findings cannot be generalised because all surveys were carried out in the same country.

Reuben M. “Fani katika Utenzi wa Ayubu” . Mbuthia DE, Amiri DS, eds. Nairobi: University of Nairobi; 2011.
Winnie Mitullah, Preston Chitere, Dorothy McCormick, Risper Orero, Ommeh. M. "‘Paratransit Business Strategies: A Bird’s Eye View of Matatus in Nairobi.’ Paper presented at the Southern African Transport Conference,." Pretoria, South Africa; 2011.
Risper Orero, Winnie Mitullah, Preston Chitere, Dorothy McCormick, Ommeh. M. "Paratransit Operations and Institutions in Nairobi.". In: 30th Southern African Transport. South Africa; 2011.
Preston Chitere, Dorothy McCormick, Winnie Mitullah, Risper Orero, Ommeh. M. "Paratransit Operations in Nairobi: Development of Their Routes and Termini, 30th Southern African Transport Conference,." Pretoria, South Africa; 2011.
Mujugira A, Baeten JM, Donnell D, Ndase P, Mugo NR, Barnes L, Campbell JD, Wangisi J, Tappero JW, Bukusi E, Cohen CR, Katabira E, Ronald A, Tumwesigye E, Were E, Fife KH, Kiarie J, Farquhar C, John-Stewart G, Kidoguchi L, Panteleeff D, Krows M, Shah H, Revall J, Morrison S, Ondrejcek L, Ingram C, Coombs RW, Lingappa JR, Celum C. "Characteristics of HIV-1 serodiscordant couples enrolled in a clinical trial of antiretroviral pre-exposure prophylaxis for HIV-1 prevention." PLoS ONE. 2011;6(10):e25828. Abstract

Stable heterosexual HIV-1 serodiscordant couples in Africa have high HIV-1 transmission rates and are a critical population for evaluation of new HIV-1 prevention strategies. The Partners PrEP Study is a randomized, double-blind, placebo-controlled trial of tenofovir and emtricitabine-tenofovir pre-exposure prophylaxis to decrease HIV-1 acquisition within heterosexual HIV-1 serodiscordant couples. We describe the trial design and characteristics of the study cohort.

Mujugira A, Baeten JM, Donnell D, Ndase P, Mugo NR, Barnes L, Campbell JD, Wangisi J, Tappero JW, Bukusi E, Cohen CR, Katabira E, Ronald A, Tumwesigye E, Were E, Fife KH, Kiarie J, Farquhar C, John-Stewart G, Kidoguchi L, Panteleeff D, Krows M, Shah H, Revall J, Morrison S, Ondrejcek L, Ingram C, Coombs RW, Lingappa JR, Celum C. "Characteristics of HIV-1 serodiscordant couples enrolled in a clinical trial of antiretroviral pre-exposure prophylaxis for HIV-1 prevention." PLoS ONE. 2011;6(10):e25828. Abstract

Stable heterosexual HIV-1 serodiscordant couples in Africa have high HIV-1 transmission rates and are a critical population for evaluation of new HIV-1 prevention strategies. The Partners PrEP Study is a randomized, double-blind, placebo-controlled trial of tenofovir and emtricitabine-tenofovir pre-exposure prophylaxis to decrease HIV-1 acquisition within heterosexual HIV-1 serodiscordant couples. We describe the trial design and characteristics of the study cohort.

John Kinuthia, James N Kiarie, Kiarie JN, Farquhar C, Richardson BA, Ruth Nduati, Mbori-Ngacha D, John-Stewart G. "Uptake of prevention of mother to child transmission interventions in Kenya: health systems are more influential than stigma." J Int AIDS Soc. 2011;14:61. Abstract

We set out to determine the relative roles of stigma versus health systems in non-uptake of prevention of mother to child transmission (PMTCT) of HIV-1 interventions: we conducted cross-sectional assessment of all consenting mothers accompanying infants for six-week immunizations.

John Kinuthia, James N Kiarie, Kiarie JN, Farquhar C, Richardson BA, Ruth Nduati, Mbori-Ngacha D, John-Stewart G. "Uptake of prevention of mother to child transmission interventions in Kenya: health systems are more influential than stigma." J Int AIDS Soc. 2011;14:61. Abstract

We set out to determine the relative roles of stigma versus health systems in non-uptake of prevention of mother to child transmission (PMTCT) of HIV-1 interventions: we conducted cross-sectional assessment of all consenting mothers accompanying infants for six-week immunizations.

Campbell MS, Mullins JI, Hughes JP, Celum C, Wong KG, Raugi DN, Sorensen S, Stoddard JN, Zhao H, Deng W, Kahle E, Panteleeff D, Baeten JM, McCutchan FE, Albert J, Leitner T, Wald A, Corey L, Lingappa JR. "Viral linkage in HIV-1 seroconverters and their partners in an HIV-1 prevention clinical trial." PLoS ONE. 2011;6(3):e16986. Abstract

Characterization of viruses in HIV-1 transmission pairs will help identify biological determinants of infectiousness and evaluate candidate interventions to reduce transmission. Although HIV-1 sequencing is frequently used to substantiate linkage between newly HIV-1 infected individuals and their sexual partners in epidemiologic and forensic studies, viral sequencing is seldom applied in HIV-1 prevention trials. The Partners in Prevention HSV/HIV Transmission Study (ClinicalTrials.gov #NCT00194519) was a prospective randomized placebo-controlled trial that enrolled serodiscordant heterosexual couples to determine the efficacy of genital herpes suppression in reducing HIV-1 transmission; as part of the study analysis, HIV-1 sequences were examined for genetic linkage between seroconverters and their enrolled partners.

Hlushchuk R, Ehrbar M, Reichmuth P, Heinimann N, Styp-Rekowska B, Escher R, Baum O, Lienemann P, Makanya A, Keshet E, Djonov V. "Decrease in VEGF expression induces intussusceptive vascular pruning." Arterioscler. Thromb. Vasc. Biol.. 2011;31(12):2836-44. Abstract

The concept of vascular pruning, the "cuting-off" of vessels, is gaining importance due to expansion of angio-modulating therapies. The proangiogenic effects of vascular endothelial growth factor (VEGF) are broadly described, but the mechanisms of structural alterations by its downregulation are not known.

Balkus JE, Richardson BA, Mandaliya K, Kiarie J, Jaoko W, Ndinya-Achola JO, Marrazzo J, Farquhar C, McClelland SR. "Establishing and sustaining a healthy vaginal environment: analysis of data from a randomized trial of periodic presumptive treatment for vaginal infections." J. Infect. Dis.. 2011;204(2):323-6. Abstract

Data from a randomized trial of oral periodic presumptive treatment (PPT) to reduce vaginal infections were analyzed to assess the effect of the intervention on a healthy vaginal environment (normal flora confirmed by Gram stain with no candidiasis or trichomoniasis). The incidence of a healthy vaginal environment was 608 cases per 100 person-years in the intervention arm and 454 cases per 100 person-years in the placebo arm (hazard ratio [HR], 1.36; 95% confidence interval [CI], 1.17-1.58). Sustained vaginal health (healthy vaginal environment for ≥3 consecutive visits) was also more frequent in the intervention arm (HR, 1.69; 95% CI, 1.23-2.33). PPT is effective at establishing and sustaining a healthy vaginal environment.

Chung MH, Richardson BA, Tapia K, Benki-Nugent S, Kiarie JN, Simoni JM, Overbaugh J, Attwa M, John-Stewart GC. "A randomized controlled trial comparing the effects of counseling and alarm device on HAART adherence and virologic outcomes." PLoS Med.. 2011;8(3):e1000422. Abstract

Behavioral interventions that promote adherence to antiretroviral medications may decrease HIV treatment failure. Antiretroviral treatment programs in sub-Saharan Africa confront increasing financial constraints to provide comprehensive HIV care, which include adherence interventions. This study compared the impact of counseling and use of an alarm device on adherence and biological outcomes in a resource-limited setting.

McClelland SR, Richardson BA, Wanje GH, Graham SM, Mutunga E, Peshu N, Kiarie JN, Kurth AE, Jaoko W. "Association between participant self-report and biological outcomes used to measure sexual risk behavior in human immunodeficiency virus-1-seropositive female sex workers in Mombasa, Kenya." Sex Transm Dis. 2011;38(5):429-33. Abstract

Few studies have examined the association between self-reported sexual risk behaviors and biologic outcomes in human immunodeficiency virus (HIV)-1-seropositive African adults.

Guthrie BL, Choi RY, Liu AY, Mackelprang RD, Rositch AF, Bosire R, Manyara L, Gatuguta A, Kiarie JN, Farquhar C. "Barriers to antiretroviral initiation in HIV-1-discordant couples." J. Acquir. Immune Defic. Syndr.. 2011;58(3):e87-93. Abstract

In Kenya and much of sub-Saharan Africa, nearly half of all couples affected by HIV are discordant. Antiretroviral therapy (ART) slows disease progression in HIV-1-infected individuals and reduces transmission to uninfected partners. We examined time to ART initiation and factors associated with delayed initiation in HIV-1-discordant couples in Nairobi.

Kim HN, Scott J, Cent A, Cook L, Morrow RA, Richardson B, Tapia K, Jerome KR, Lule G, John-Stewart G, Chung MH. "HBV lamivudine resistance among hepatitis B and HIV coinfected patients starting lamivudine, stavudine and nevirapine in Kenya." J. Viral Hepat.. 2011;18(10):e447-52. Abstract

Widespread use of lamivudine in antiretroviral therapy may lead to hepatitis B virus resistance in HIV-HBV coinfected patients from endemic settings where tenofovir is not readily available. We evaluated 389 Kenyan HIV-infected adults before and for 18 months after starting highly active antiretroviral therapy with stavudine, lamivudine and nevirapine. Twenty-seven (6.9%) were HBsAg positive and anti-HBs negative, 24 were HBeAg negative, and 18 had HBV DNA levels ≤ 10,000 IU/mL. Sustained HBV suppression to <100 IU/mL occurred in 89% of 19 evaluable patients. Resistance occurred in only two subjects, both with high baseline HBV DNA levels. Lamivudine resistance can emerge in the setting of incomplete HBV suppression but was infrequently observed among HIV-HBV coinfected patients with low baseline HBV DNA levels.

Kim HN, Scott J, Cent A, Cook L, Morrow RA, Richardson B, Tapia K, Jerome KR, Lule G, John-Stewart G, Chung MH. "HBV lamivudine resistance among hepatitis B and HIV coinfected patients starting lamivudine, stavudine and nevirapine in Kenya." J. Viral Hepat.. 2011;18(10):e447-52. Abstract

Widespread use of lamivudine in antiretroviral therapy may lead to hepatitis B virus resistance in HIV-HBV coinfected patients from endemic settings where tenofovir is not readily available. We evaluated 389 Kenyan HIV-infected adults before and for 18 months after starting highly active antiretroviral therapy with stavudine, lamivudine and nevirapine. Twenty-seven (6.9%) were HBsAg positive and anti-HBs negative, 24 were HBeAg negative, and 18 had HBV DNA levels ≤ 10,000 IU/mL. Sustained HBV suppression to <100 IU/mL occurred in 89% of 19 evaluable patients. Resistance occurred in only two subjects, both with high baseline HBV DNA levels. Lamivudine resistance can emerge in the setting of incomplete HBV suppression but was infrequently observed among HIV-HBV coinfected patients with low baseline HBV DNA levels.

Mugo NR, Heffron R, Donnell D, Wald A, Were EO, Rees H, Celum C, Kiarie JN, Cohen CR, Kayintekore K, Baeten JM. "Increased risk of HIV-1 transmission in pregnancy: a prospective study among African HIV-1-serodiscordant couples." AIDS. 2011;25(15):1887-95. Abstract

Physiologic and behavioral changes during pregnancy may alter HIV-1 susceptibility and infectiousness. Prospective studies exploring pregnancy and HIV-1 acquisition risk in women have found inconsistent results. No study has explored the effect of pregnancy on HIV-1 transmission risk from HIV-1-infected women to male partners.

Mureithi SM, Njoka JT, Gachene CKK, Verdoodt A, Warinwa F, Ranst VE. "Impact of rehabilitated sites on herbivore dynamics in a livestock-wildlife interface in Laikipia, Kenya. CBD Technical Series. 62. p.78-80.". In: CBD SBSTTA 15 - Fifteenth meeting of the Subsidiary Body on Scientific, Technical and Technological Advice. Montreal, Canada: Rangeland Ecology & Management; 2011. Abstract

Refer Website

Reese BE. "Development of the retina and optic pathway." Vision research. 2011;51:613-632. Abstract

Our understanding of the development of the retina and visual pathways has seen enormous advances during the past 25years. New imaging technologies, coupled with advances in molecular biology, have permitted a fuller appreciation of the histotypical events associated with proliferation, fate determination, migration, differentiation, pathway navigation, target innervation, synaptogenesis and cell death, and in many instances, in understanding the genetic, molecular, cellular and activity-dependent mechanisms underlying those developmental changes. The present review considers those advances associated with the lineal relationships between retinal nerve cells, the production of retinal nerve cell diversity, the migration, patterning and differentiation of different types of retinal nerve cells, the determinants of the decussation pattern at the optic chiasm, the formation of the retinotopic map, and the establishment of ocular domains within the thalamus.

Reese BE. "Development of the retina and optic pathway." Vision research. 2011;51:613-632. Abstract

Our understanding of the development of the retina and visual pathways has seen enormous advances during the past 25years. New imaging technologies, coupled with advances in molecular biology, have permitted a fuller appreciation of the histotypical events associated with proliferation, fate determination, migration, differentiation, pathway navigation, target innervation, synaptogenesis and cell death, and in many instances, in understanding the genetic, molecular, cellular and activity-dependent mechanisms underlying those developmental changes. The present review considers those advances associated with the lineal relationships between retinal nerve cells, the production of retinal nerve cell diversity, the migration, patterning and differentiation of different types of retinal nerve cells, the determinants of the decussation pattern at the optic chiasm, the formation of the retinotopic map, and the establishment of ocular domains within the thalamus.

Mwachaka PM, Ranketi SS, Nchafatso OG, Kasyoka BM, Kiboi JG. "Spinal tuberculosis among human immunodeficiency virus-negative patients in a {Kenyan} tertiary hospital: a 5-year synopsis." The spine journal: official journal of the North American Spine Society. 2011;11:265-269. Abstract

BACKGROUND CONTEXT Spinal tuberculosis (TB) accounts for more than half of all cases of skeletal TB. Although Kenya has one of the highest burdens of TB, data on spinal TB in this country remain scarce. PURPOSE To highlight the clinical presentation and management of this condition in our setup. STUDY DESIGN Retrospective study. SETTING Kenyatta National Hospital in Kenya. PATIENT SAMPLE One hundred twenty-nine patients. OUTCOME MEASURES Patients' condition after intervention and duration of hospital stay. METHODS This study involved review of patients admitted to our hospital between 2004 and 2009 with a diagnosis of spinal TB. RESULTS The most common presenting complaints were back pain in 100 patients (77.5%) and limb weakness in 94 patients (72.9%), whereas the most frequent physical examination finding was gibbus deformity in 85 patients (65.8%). Most (79 patients, 61.2%) had severe motor and sensory impairment graded as either American Spinal Injury Association (ASIA) A or ASIA B. Imaging revealed multiple vertebrae disease in 90 patients (79.6%). Of these, the most common was two vertebrae disease in 77 patients (68.1%). All patients were managed using anti-TB drugs and analgesics; however, 33 (25.6%) required adjunctive operative management. Mean hospital stay was 53.3 days. Marked clinical improvement was seen in 91 patients (70.0%) within 6 months of treatment. CONCLUSION Patients with spinal TB in our setting tended to present late and with advanced disease. Therefore, a high index of suspicion should be maintained and appropriate chemotherapy started as early as possible.

Paul UK, Naushaba H, Alam MJ, Begum T, Rahman A, Akhter J. "Length of {Vermiform} {Appendix}: {A} {Postmortem} {Study}." Bangladesh Journal of Anatomy. 2011;9. AbstractWebsite
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ODERA BO, Cornish LA, Rading GO, Papo MJ. "Solidification projection of the Pt-Al-V system at the Pt-rich corner.". In: Proceedings of the Microscopic Society of Southern Africa Conference. Pretoria, South Africa; 2011.
Rudebjer P, Chakeredza S, Dansi A, Ekaya W, Ghezae N, Aboagye LM, Kwapata M, Njoroge K, Padulosi S. "Beyond commodity crops: Strengthening young scientists’ capacity for research on underutilized species in Sub-Saharan Africa.". In: 2nd International Symposium on Underutilised Plant Species. Kuala Lumpur, Malaysia; 2011.
Savage MW, Dhatariya KK, Kilvert A, Rayman G, a. Rees JE, Courtney CH, Hilton L, Dyer PH, Hamersley MS, Joint British Diabetes Societies. "Joint {British} {Diabetes} {Societies} guideline for the management of diabetic ketoacidosis." Diabetic Medicine: A Journal of the British Diabetic Association. 2011;28:508-515. Abstract

The Joint British Diabetes Societies guidelines for the management of diabetic ketoacidosis (these do not cover Hyperosmolar Hyperglycaemic Syndrome) are available in full at: (i) http://www.diabetes.org.uk/About\_us/Our\_Views/Care\_recommendations/The-Management-of-Diabetic-Ketoacidosis-in-Adults; (ii)  http://www.diabetes.nhs.uk/publications\_and\_resources/reports\_andġuidance; (iii) http://www.diabetologists-abcd.org.uk/JBDS\_DKA\_Management.pdf. This article summarizes the main changes from previous guidelines and discusses the rationale for the new recommendations. The key points are: Monitoring of the response to treatment (i) The method of choice for monitoring the response to treatment is bedside measurement of capillary blood ketones using a ketone meter. (ii) If blood ketone measurement is not available, venous pH and bicarbonate should be used in conjunction with bedside blood glucose monitoring to assess treatment response. (iii) Venous blood should be used rather than arterial (unless respiratory problems dictate otherwise) in blood gas analysers. (iv) Intermittent laboratory confirmation of pH, bicarbonate and electrolytes only. Insulin administration (i) Insulin should be infused intravenously at a weight-based fixed rate until the ketosis has resolved. (ii) When the blood glucose falls below 14 mmol/l, 10% glucose should be added to allow the fixed-rate insulin to be continued. (iii) If already taking, long-acting insulin analogues such as insulin glargine (Lantus(®), Sanofi Aventis, Guildford, Surry, UK) or insulin detemir (Levemir(®), Novo Nordisk, Crawley, West Sussex, UK.) should be continued in usual doses. Delivery of care (i) The diabetes specialist team should be involved as soon as possible. (ii) Patients should be nursed in areas where staff are experienced in the management of ketoacidosis.

Jung B, Rimmele T, Goff CL, Chanques G, Corne P, Jonquet O, Muller L, Lefrant J-Y, Guervilly C, Papazian L, Allaouchiche B, Jaber S, firstName \$author.lastName \$author. "Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. a prospective, multiple-center study." Critical Care. 2011;15:R238. AbstractWebsite

In this study, we sought describe the incidence and outcomes of severe metabolic or mixed acidemia in critically ill patients as well as the use of sodium bicarbonate therapy to treat these illnesses. PMID: 21995879

ODERA BO, Cornish LA, Shongwe MB, Rading GO, Papo MJ. "A study of some as-cast and heat treated alloys of the Pt-Al-V system at the Pt-rich corner.". In: Proceedings of the ZrTa New Metals Development Network Conference at Mount Grace Country House and Spa, Magaliesburg. The Southern African Institute of Mining and Metallurgy, Advanced Metals Initiative; 2011.
2012
Bulimo W, KK W, WD B, J M, RA A, SK S, M S, JM M, MO W, FA O, SO M, JK M, JM W, JN M, JO N, BD O, BH O, KK M, J B, S L, DC S. "Epidemiology of 2009 pandemic influenza A virus subtype H1N1 among Kenyans aged 2 months to 18 years, 2009-2010.". 2012. AbstractWebsite
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Bulimo W, CO O, R N, S K, R A, W B, SR W, PA C, RN G, LL H, JA S, JA B, DJ N. "Influenza surveillance among children with pneumonia admitted to a district hospital in coastal Kenya, 2007-2010.". 2012. AbstractWebsite
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Bulimo W, WD B, RA A, J M, S M, M W, F O, J M, J N, J W, J N, B O, K M, D O, S S, M N, A O, C A, J K, R M, F M, G K, M M, D K, E M, D K, S K, M K, A S, ' O, DC S. "Molecular characterization and phylogenetic analysis of the hemagglutinin 1 protein of human influenza A virus subtype H1N1 circulating in Kenya during 2007-2008.". 2012. AbstractWebsite
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Rintaugu EG, Masiga M, Mwangi IM, Were H, Litaba SA, Kinoti J, Kubai JI. "Psycho-social attributes of Kenyan university athletes: social learning and motivational theories perspectives.". 2012. Abstract
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Stenmark KR, Yeager M, Riddle S, El Kasmi KC, Frid MG, Li M, McKinsey T. "Targeting the adventitial microenvironment in pulmonary hypertension: {A} potential approach to therapy that considers epigenetic change." Pulmonary Circulation. 2012;2:3. AbstractWebsite
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R NYONJE, KYALO DN, MULWA ANELINE. ). Monitoring and Evaluation of Projects and Programmes: A Hand Book for Students and Practioners. Nairobi: Aura Books-ISBN 9966-123-456-7 ; 2012.
Konyole SO, Kinyuru JN, Owuor BO, Kenji GM, Onyango CA, Estambale BB, Friis H, Roos N, Owino VO. "Acceptability of Amaranth Grain-based Nutritious Complementary Foods with Dagaa Fish (Rastrineobola argentea) and Edible Termites (Macrotermes subhylanus) Compared to Corn Soy Blend Plus among Young Children/Mothers Dyads in Western Kenya.". 2012. AbstractWebsite

This paper reports on a prospective study conducted between June 1990 and June 1992 to determine method acceptability, user satisfaction and continuation rates for three highly effective and reversible contraceptive methods currently available in Kenya: the CuT 380A (IUCD), the injectable, Depo-Provera and the low-dose oral contraceptive pill, Microgynon. A non-randomised sample of volunteer participants was used. One thousand and seventy-six users were followed up for a period of one year or up to the time of discontinuation of the method, whichever came earlier. Analysis revealed method specific differences in users' characteristics. The OC users were younger and had fewer children than the IUCD or Depo-Provera users. The Depo-Provera users were older, and had the largest family sizes. Many OC users (almost 40%) were single, while almost three-quarters of IUCD and Depo-Provera users were married. IUCD users were also more educated compared to OC and Depo-Provera users. Survival analysis was used to calculate cumulative life table discontinuation rates by method for the 12 month period. Discontinuation rates were highest for OC users (80%) and lowest for IUCD users (20%) and intermediate for Depo-Provera users (39%). Ninety percent of OC and Depo-Provera users and 86% of IUCD users said they were satisfied with their respective methods. While OCs are among the most popular family planning methods in Kenya, they are also one of the most problematic, while IUCD has the fewest compliance problems. Service providers need to address the issue of high discontinuation rates among the young OC users.
PIP:
This paper reports on a prospective study conducted between June 1990 and June 1992 to determine method acceptability, user satisfaction, and continuation rates for three highly effective and reversible contraceptive methods currently available in Kenya: the CuT 380A IUD; the injectable Depo-Provera; and the low-dose oral contraceptive Microgynon. A nonrandomized sample of volunteer participants was used. 1076 users were followed up for a period of 1 year or up to the time of discontinuation of the method, whichever came earlier. Analysis revealed method-specific differences in users' characteristics. The OC users were younger and had fewer children than the IUD or Depo-Provera users. The Depo-Provera users were older and had the largest family sizes. Many OC users (almost 40%) were single, while almost three-quarters of the IUD and Depo-Provera users were married. IUD users were also more educated compared to OC and Depo-Provera users. Survival analysis was used to calculate cumulative life table discontinuation rates by method for the 12-month period. Discontinuation rates were highest for OC users (80%), lowest for IUD users (20%), and intermediate for Depo-Provera users (39%). 90% of OC and Depo-Provera users and 86% of IUD users said they were satisfied with their respective methods. While OCs are among the most popular family planning methods in Kenya, they are also one of the most problematic, while IUDs have shown the fewest compliance problems. Service providers need to address the issue of high discontinuation rates among young OC users

Slyker JA, Rowland-Jones SL, Dong T, Reilly M, Richardson B, Emery VC, Atzberger A, Mbori-Ngacha DA, Lohman-Payne BL, John-Stewart GC. "Acute cytomegalovirus infection is associated with increased frequencies of activated and apoptosis-vulnerable T cells in HIV-1-infected infants.". 2012. AbstractWebsite

Cytomegalovirus (CMV) coinfection is associated with infant HIV-1 disease progression and mortality. In a cohort of Kenyan HIV-infected infants, the frequencies of activated (CD38(+) HLA-DR(+)) and apoptosis-vulnerable (CD95(+) Bcl-2(-)) CD4(+) and CD8(+) T cells increased substantially during acute CMV infection. The frequency of activated CD4(+) T cells was strongly associated with both concurrent CMV coinfection (P = 0.001) and HIV-1 viral load (P = 0.05). The frequency of apoptosis-vulnerable cells was also associated with CMV coinfection in the CD4 (P = 0.02) and CD8 (P < 0.001) T cell subsets. Similar observations were made in HIV-exposed uninfected infants. CMV-induced increases in T cell activation and apoptosis may contribute to the rapid disease progression in coinfected infants.

Nthakanio NP, Ireri KJ, Munji. KJ, Raphael W. Adaptability of PGMS and TGMS rice lines for hybrid rice seed production in Kenya..; 2012.
Musumba GW, R.O. O, E.T.O. O. "Agent Based Adaptive Learning Model for Intermittent Internet Connection Conditions." Journal of Continuing, Open and Distance Education. 2012.
Musumba GW, R.Oboko GW, E.T.Omulo O. "Agent Based Adaptive Learning Model for Intermittent Internet Connection Conditions." Journal of Continuing, Open and Distance Education. 2012.
Rintaugu EG, Mwisukha A, Onywera VO. "Analysis of Factors that affect the standard of soccer in Africa. The case of East African countries." Journal of Physical Education and Sport (JPES). 2012;12(1):135-139.
Nwaka S, Ochem A, Besson D, Ramirez B, Fakorede F, Botros S, Inyang U, Mgone C, Adae-Mensah I, Konde V, Nyasse B, Okole B, Guantai A, Loots G, Atadja P, Ndumbe P, Sanou I, Olesen O, Ridley R, Ilunga T. "Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent." 12. 2012;11(12):2-15.analysis_of_pan-african_centres_of_excellence_in_health_innovation_highlights_opportunities_and_challenges_for_local_innovation_and_in.pdf
Drannik AG, Nag K, Yao X-D, Henrick BM, Jain S, Ball BT, Plummer FA, Wachihi C, Kimani J, Rosenthal KL. "Anti-HIV-1 Activity of Elafin Is More Potent than Its Precursor's, Trappin-2, in Genital Epithelial Cells.". 2012. AbstractWebsite

Cervicovaginal lavage fluid (CVL) is a natural source of anti-HIV-1 factors; however, molecular characterization of the anti-HIV-1 activity of CVL remains elusive. In this study, we confirmed that CVLs from HIV-1-resistant (HIV-R) compared to HIV-1-susceptible (HIV-S) commercial sex workers (CSWs) contain significantly larger amounts of serine antiprotease trappin-2 (Tr) and its processed form, elafin (E). We assessed anti-HIV-1 activity of CVLs of CSWs and recombinant E and Tr on genital epithelial cells (ECs) that possess (TZM-bl) or lack (HEC-1A) canonical HIV-1 receptors. Our results showed that immunodepletion of 30% of Tr/E from CVL accounted for up to 60% of total anti-HIV-1 activity of CVL. Knockdown of endogenous Tr/E in HEC-1A cells resulted in significantly increased shedding of infectious R5 and X4 HIV-1. Pretreatment of R5, but not X4 HIV-1, with either Tr or E led to inhibition of HIV-1 infection of TZM-bl cells. Interestingly, when either HIV-1 or cells lacking canonical HIV-1 receptors were pretreated with Tr or E, HIV-1 attachment and transcytosis were significantly reduced, and decreased attachment was not associated with altered expression of syndecan-1 or CXCR4. Determination of 50% inhibitory concentrations (IC50) of Tr and E anti-HIV-1 activity indicated that E is ~130 times more potent than its precursor, Tr, despite their equipotent antiprotease activities. This study provides the first experimental evidence that (i) Tr and E are among the principal anti-HIV-1 molecules of CVL; (ii) Tr and E affect cell attachment and transcytosis of HIV-1; (iii) E is more efficient than Tr regarding anti-HIV-1 activity; and (iv) the anti-HIV-1 effect of Tr and E is contextual

Endale M, Alao JP, Akala HM, Rono NK, Eyase FL, Solomon D, Ndakala A, Mbugua M, Walsh DS, Erdelyl M, Yenesew A. "Antiplasmodial Quinones from Pentas longiflora and Pentas lanceolata." Planta Medica . 2012;78(1):31-35.
ODERA BO, Cornish LA, Shongwe MB, Rading GO, Papo MJ. "As-cast and heat-treated alloys of the Pt-Al-V system at the Pt-rich corner." The Journal of Southern African Institute of Mining and Metallurgy. 2012;7A:505-515.
Ndambiri HK;, Ritho C;, Mbogoh SG;, Ng’ang’a SI;, Muiruri EJ;, Nyangweso PM;, Kipsat MJ;, Ogada JO;, Omboto PI;, Kefa C;, Kubowon PC;, Cherotwo FH. "Assessment of Farmers' Adaptation to the Effects of Climate Change in Kenya: the Case of Kyuso District.". 2012. Abstract

The study was carried out to assess how farmers in Kyuso District have adapted to the effects of climate change. Survey data was collected from 246 farmers from six locations that were sampled out through a multistage and simple random sampling procedure. The probit regression model was fitted into the data in order to assess factors influencing farmers’ adaptation to the effects of climate change. The analysis revealed that 85% of the farmers had adapted in various ways to the effects of climate change. In this regard, the age of the farmer, gender, education, farming experience, farm income, access to climate information, household size, local agro-ecology, distance to input/output market, access to credit, access to water for irrigation, precipitation and temperature were found to have significant influence on the probability of farmers to adapt to climate change. The study suggests that more policy efforts should thus be geared towards helping all the farmers in the district to adapt to climate change.

Murila F, Obimbo MM, R. M. "Assessment of knowledge on neonatal resuscitation amongst health care providers in Kenya." Pan Afr Med J. 2012;11:78. Epub 2012 Apr 24.. 2012. Abstract

Abstract
INTRODUCTION:
Competence in neonatal resuscitation, which represents the most urgent pediatric clinical situation, is critical in delivery rooms to ensure safety and health of newly born infants. The challenges experienced by health care providers during this procedure are unique due to different causes of cardio respiratory arrest. This study aimed at assessing the knowledge of health providers on neonatal resuscitation.
METHODS:
Data were gathered among 192 health providers drawn from all counties of Kenya. The clinicians were asked to complete questionnaires which were in two parts as; demographic information and assessment of their knowledge by different scenarios which were formatted in the multiple choice questions. Data were analyzed using SPSS version 15.0 for windows. The results are presented using tables.
RESULTS:
All the participants were aged 23 years and above with at least a certificate training. Most medical providers had heard of neonatal resuscitation (85.4%) with only 23 receiving formal training. The average duration of neonatal training was 3 hours with 50% having missed out on practical exposure. When asked on steps of resuscitation, only 68 (35.4%) of the participants scored above 85%. More than 70% of them considered their knowledge about neonatal resuscitation inadequate and blamed it on inadequate medical training programs.
CONCLUSION:
Health providers, as the key personnel in the management of neonatal resuscitation, in this survey seem to have inadequate training and knowledge on this subject. Increasing the duration and quality of formal training should be considered during the pre-service medical education to ensure acceptable neonatal outcome.

Rading GO. "B O Odera, L A Cornish, M B Shongwe, G O Rading and M J Papo: As Cast and Heat Treated Alloys of the Pt-Al-V System at the Pt-Rich Corner." Journal of the Southern Africa Institute of Mining and Metallurgy. 2012;7A:505-515.
Ongarora DSB, Gut J, Rosenthal PJ, Masimirembwa CM. "Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: Synthesis and pharmacological evaluation." Bioorg. Med. Chem. Lett. . 2012;22(15):5046-5050.
Lohman-Payne B, Slyker JA MS, Maleche-Obimbo E, Richardson BA, Mbori-Ngacha D, Farquhar C O, Overbaugh J J-SG. "Breast milk cellular HIV-specific interferon γ responses are associated with protection from peripartum HIV transmission." AIDS. 2012 Oct 23;26(16):2007-16. doi: 10.1097/QAD.0b013e328359b7e0.. 2012. Abstract

Abstract
OBJECTIVE:
Breast milk is a major route of infant HIV infection, yet the majority of breast-fed, HIV-exposed infants escape infection by unknown mechanisms. This study aimed to investigate the role of HIV-specific breast milk cells in preventing infant HIV infection.
DESIGN:
A prospective study was designed to measure associations between maternal breast milk HIV-specific interferon-γ (IFN-γ) responses and infant HIV-1 detection at 1 month of age.
METHODS:
In a Kenyan cohort of HIV-infected mothers, blood and breast milk HIV-gag IFN-γ ELISpot responses were measured. Logistic regression was used to measure associations between breast milk IFN-γ responses and infant HIV infection at 1 month of age.
RESULTS:
IFN-γ responses were detected in breast milk from 117 of 170 (69%) women. IFN-γ responses were associated with breast milk viral load, levels of macrophage inflammatory protein (MIP) 1α, MIP-1β, regulated upon activation, normal T-cell expressed, and secreted and stromal-cell derived factor 1 and subclinical mastitis. Univariate factors associated with infant HIV infection at 1 month postpartum included both detection and breadth of breast milk IFN-γ response (P = 0.08, P = 0.04, respectively), breast milk MIP-1β detection (P = 0.05), and plasma (P = 0.004) and breast milk (P = 0.004) viral load. In multivariate analyses adjusting for breast milk viral load and MIP-1β, breast milk IFN-γ responses were associated with an approximately 70% reduction in infant HIV infection [adjusted odds ratio (aOR) 0.29, 95% confidence interval (CI) 0.092-0.91], and each additional peptide pool targeted was associated with an approximately 35% reduction in infant HIV (aOR 0.65, 95% CI 0.44-0.97).
CONCLUSION:
These data show breast milk HIV-gag-specific IFN-γ cellular immune responses are prevalent and may contribute to protection from early HIV transmission. More broadly, these data suggest breast milk cellular responses are potentially influential in decreasing mother-to-child transmission of viruses.

Tonya Renee Thurman, Jarabi B, Rice J. "Caring for the caregiver: evaluation of support groups for guardians of orphans and vulnerable children in Kenya, AIDS Care." Psychological and Socio-medical Aspects of AIDS/HIV, DOI:10.1080/09540121.2011.644229. 2012.
Blish CA, Dogan OC, Jaoko W, McClelland RS, Mandaliya K, Odem-Davis KS, Richardsonb BA, Overbaugh J. "Cellular Immune Responses And Susceptibility To HIV-1 Superinfection: A Case-control Study.". 2012. AbstractWebsite

A case-control study was performed to determine the effects of HIV-1-specific cellular immune responses on the odds of acquiring a second HIV-1 infection (superinfection). Changes in the frequency of cytokine-producing or cytolytic CD8+ or CD4+ T cells were not associated with significant alterations in the odds of superinfection, suggesting that HIV-1 specific cellular immune responses at the level induced by chronic infection do not appear to significantly contribute to protection from HIV-1 superinfection.

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