Assessment of herbal anthelmintics used by the farmers in Kirinyaga county, Kenya, for the treatment of helminthiosis in cattle.

Citation:
S. M. Githigia, M. Mutugi, P. G. Kareru, F. K. Njonge, R. Waihenya, Nyakundi. WO. "Assessment of herbal anthelmintics used by the farmers in Kirinyaga county, Kenya, for the treatment of helminthiosis in cattle." African Journal of Pharmacy and Pharmacology. 2013;Vol. 7(29):2100-2104.

Abstract:

The aim of this study was to assess and validate the herbal anthelmintic remedies used by farmers in
Kirinyaga county, Kenya for the treatment of their cattle against gastrointestinal nematodes. The herbs
used were identified via questionnaire surveys through focused group discussions. The aqueous
extracts of plants used: Aspillia pluriseta, Vernonia lasiopus, Entada leptostachya and Erythrina
abyssinica were prepared and using dosage between 10 and 30%, the viability of infective strongyle
larvae were assessed for a period of 48 h. The results of the in vitro antihelmintic study indicated a high
to moderate anthelmintic activity for the tested extracts. E. leptostachya exhibited the highest in vitro
anthelmintic activity, while E. abyssinica had the lowest activity. The anthelmintic activity may have
been due to the presence of saponins in the herbal remedies. There was a positive correlation between
the saponin concentration and the anthelmintic activity of the extracts. In general, the in vitro
anthelmintic activity increased with the extract concentration for the medicinal plants examined.

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