Antimicrobial activity and phytochemical screening of Senna didymobotry used to treat bacterial and fungal infections in Kenya

Citation:
Kitonde CK, Dossaji SF, Lukhoba CW, Jumba MM. "Antimicrobial activity and phytochemical screening of Senna didymobotry used to treat bacterial and fungal infections in Kenya." International Journal of Education and Research. 2014;2(No. 1):1-12.

Abstract:

Infectious diseases are prevalent and life threatening in Kenya. The majority of the sick are seeking
herbal remedies in search of effective, safe, and affordable treatments. This study aimed to
investigate the antimicrobial activity and presence of chemical compounds in different parts of
Senna didymobotrya. Results showed that, organic extracts of root with Mean inhibition zone (MIZ)
of 1.58 cm, recorded the highest activity against S. aureus than the standard antibiotic
(Streptomycin MIZ of 1.30 cm. Flavonoids were the chemical compoundshighly present. The
results of this study suggest that S. didymobotrya has significant antimicrobial properties and justify
its use in traditional herbal medicine for the management of microbial based diseases. Cytotoxicity
assays are highly recommended for S. didymobotrya in order to verify, validate and document its
safety in medicine.
Key words: Prevalent, Effective, Herbal, Senna didymobotrya.

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