Polymyxin B and rifampin: new regimen for multiresistant Serratia marcescens infections.

Citation:
Polymyxin B and rifampin: new regimen for multiresistant Serratia marcescens infections., Ostenson, R. C., Fields B. T., and Nolan C. M. , Antimicrobial agents and chemotherapy, 1977 Dec, Volume 12, Issue 6, p.655-9, (1977) copy at http://profiles.uonbi.ac.ke/rmkibugi/publications/polymyxin-b-and-rifampin-new-regimen-multiresistant-serratia-marcescens-infect

Abstract:

Polymyxin B and rifampin were given to 12 patients with multi-drug-resistant nosocomial Serratia marcescens infections. Eight cures were achieved; drug hepatotoxicity occurred once; one fatal suprainfection was encountered; and two patients died during therapy of causes related to severe underlying illnesses. Polymyxin B and rifampin were uniformly synergistic in vitro against the infecting strains and against 40 additional clinical isolates of S. marcescens.

Notes:

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