Perinatal Transmission Of Hepatitis B Virus In Kenya: Its Relation To The Presence Of Serum Hbv-dna And Anti-hbe In The Mother

Citation:
Greenfield C, Osidiana V, Karayiannis P, Galpin S, Musoke R, Jowett TP, Mati P, Tukei PM, Thomas HC. "Perinatal Transmission Of Hepatitis B Virus In Kenya: Its Relation To The Presence Of Serum Hbv-dna And Anti-hbe In The Mother.". 1986.

Abstract:

In Kenya hepatitis B virus (HBV) infection and its sequelae are common. We followed up 49 hepatitis B surface antigen (HBsAg)- positive mothers and their newborn infants for 9 months to determine the importance of perinatal transmission in the African and to relate this to the HBe and HBV-DNA status of the mother. Our study shows that perinatal transmission is relatively unimportant in Kenya and that this may be a consequence of the low levels of circulating HBV-DNA in the maternal plasma. These results imply that vaccination without hyperimmune globulin may be adequate to control HBV infection in Kenya

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