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Muloi D., Pablo A, Ombui JN., Ngeiywa JK., Abdullahi B, Muinde, P, Karani MK., Jonathan R, Fevre E. "Value chain analysis and sanitary risks of the camel milk system supplying Nairobi city, Kenya." Prev. Vet. Med.. 2018;159: 203-210:203-210.
Muloi D., Pablo A, Ombui JN., Ngeiywa JK., Abdullahi B, Muinde, P, Karani MK., Jonathan R, Fevre E. "Value chain analysis and sanitary risks of the camel milk system supplying Nairobi city, Kenya." Prev. Vet. Med.. 2018;159: 203-210:203-210.
Muloi D., Pablo A, Ombui JN., Ngeiywa JK., Abdullahi B, Muinde, P, Karani MK., Jonathan R, Fevre E. "Value chain analysis and sanitary risks of the camel milk system supplying Nairobi city, Kenya." Prev. Vet. Med.. 2018;159: 203-210:203-210.
and H. Indangasi MOAM. "Value Creating Education in Kenya: Building a Humane Society." Kenya Literature Bureau. 2018.
Ondicho TG. "Violence against women in Kenya: a public health problem." International Journal of Development and |Sustainability. 2018;7(6):2030-2047.ijds-v7n6-19.pdf
Mwangi HN, Onyango, Omosa LK, Mulaa F. "Virtual Screening and Validation of Potential Lead Compound from the Malaria Box against Plasmodium Falciparum S7 and S19 Proteins." Journal of Pharmaceutical Research. 2018;2(2).
Sila JM, Guto PM, Michira IN, Mwaura FB. "Voltammetric Determination of Penicillin G in Sodium Dodecyl Sulfate/Acetet Buffer Media on Glassy carbon Electrode." international journal of Sciences: Basic and Applied Research (IJSBAR). 2018;42(4):144-155.
Foster C, Graham M, Mann L, Waema T, Friederici N. "Who controls the digital? Value chains and the challenges of connectivity for East African firms." Economic Geography. 2018;94(1):68-86. AbstractFull text link

In recent years, Internet connectivity has greatly improved across the African continent. This article examines the consequences that this shift has had for East African firms that are part of global value chains (GVCs). Prior work yielded contradictory expectations: firms might benefit from connectivity through increased efficiencies and improved access to markets, although they might also be further marginalized through increasing control of lead firms. Drawing on extensive qualitative research in Kenya and Rwanda,including 264 interviews, we examine 3 sectors (tea, tourism, and business process outsourcing) exploring overarching, cross-cutting themes. The findings support more pessimistic expectations: small African producers are only thinly digitally integrated in GVCs. Moreover, shifting modes of value chain governance, supported by lead firms and facilitated by digital information platforms and data standards are leading to new challenges for firms looking to digitally integrate. Nevertheless, we also find examples in these sectors of opportunities where small firms are able to cater to emerging niche customers, and local or regional markets. Overall, the study shows that improving connectivity does not inherently benefit African firms in GVCs without support for complementary capacity and competitive advantages.

Mungania BG. Word order in the Kiswahili clause: a Minimalist approach. Schroeder H, Okombo O, eds. Nairobi: University of Nairobi; 2018.
Odundo Paul Amolloh, Wanjiru KG, Lilian GK. "Work-based Learning, Procedural Knowledge and Teacher Trainee Preparedness towards Teaching Practice at the University of Nairobi, Kenya. ." The International Journal of Learning, Teaching and Educational Research. . 2018;17(3):96-110.
m, m. "’The Relevance of Odera Oruka’s Parental Earth Ethics as an Eco-Philosophy .". In: Odera Oruka in the Twenty-first Century Kenyan Philosophical Studies, II. Washington, D.C: The Council for Research in Values and Philosophy; 2018.
SWALEH AMIRI. "“Kosa la Nani?”.". In: “Kosa la Nani?” Na Hadithi Nyingine . Nairobi: Vide-Muwa; 2018.
Kunyanga C. "“This is how Agriculture can drive Vision 2030”." The Standard (2018).
Amadi JA, Olago DO, Ong’amo GO, Oriaso SO, Nyamongo IK, Estambale BBA. "“We don’t want our clothes to smell smoke”: changing malaria control practices and opportunities for integrated community-based management in Baringo, Kenya." BMC public health. 2018;18(1):609. AbstractFull Text


The decline in global malaria cases is attributed to intensified utilization of primary vector control interventions and artemisinin-based combination therapies (ACTs). These strategies are inadequate in many rural areas, thus adopting locally appropriate integrated malaria control strategies is imperative in these heterogeneous settings. This study aimed at investigating trends and local knowledge on malaria and to develop a framework for malaria control for communities in Baringo, Kenya.


Clinical malaria cases obtained from four health facilities in the riverine and lowland zones were used to analyse malaria trends for the 2005–2014 period. A mixed method approach integrating eight focus group discussions, 12 key informant interviews, 300 survey questionnaires and two stakeholders’ consultative forums were used to assess local knowledge on malaria risk and develop a framework for malaria reduction.


Malaria cases increased significantly during the 2005–2014 period (tau = 0.352; p < 0.001) in the riverine zone. March, April, May, June and October showed significant increases compared to other months. Misconceptions about the cause and mode of malaria transmission existed. Gender-segregated outdoor occupation such as social drinking, farm activities, herding, and circumcision events increased the risk of mosquito bites. A positive relationship occurred between education level and opinion on exposure to malaria risk after dusk (χ2 = 2.70, p < 0.05). There was over-reliance on bed nets, yet only 68% (204/300) of respondents owned at least one net. Complementary malaria control measures were under-utilized, with 90% of respondents denying having used either sprays, repellents or burnt cow dung or plant leaves over the last one year before the study was conducted. Baraza, radios, and mobile phone messages were identified as effective media for malaria information exchange. Supplementary strategies identified included unblocking canals, clearing Prosopis bushes, and use of community volunteers and school clubs to promote social behaviour change.


The knowledge gap on malaria transmission should be addressed to minimize the impacts and enhance uptake of appropriate malaria management mechanisms. Implementing community-based framework can support significant reductions in malaria prevalence by minimizing both indoor and outdoor malaria transmissions.


Local knowledgeMalaria trendsCommunity-based strategiesFramework

Kang’ethe EK, H Korhonen, KA Marimba, G Nduhiu, JK Mungatu, Okoth SA, V Joutsjoki, LW Wamae, Shalo P. "肯尼亚地区对玉米中霉菌毒素引起的健康风险的管理和降低." Food Quality and Safety. 2018;1(4):268-274.
Kibugi R. "Common but differentiated responsibilities in a North-South context: assessment of the evolving practice under climate change treaties.". In: Elgar Encyclopedia of Environmental Law. Edward Elgar Publishing Limited; 2018:. Abstract
Ouko C, Mulwa R, Kibugi R, Owuor M, Zaehringer J, Oguge N. "Community Perceptions of Ecosystem Services and the Management of Mt. Marsabit Forest in Northern Kenya." Environments. 2018;5(11):121. Abstract
Omollo EO, Wasonga OV, Elhadi MY, Mnene WN. "Determinants of pastoral and agro-pastoral households." Pastoralism. 2018;8:9. Abstract
Kalambuka Angeyo H. "Developing Kenya." International Journal of Nuclear Security. 2018;4:2. Abstract
NALYANYA KM, Ronald ROPK, ONYUKA A, Birech Z, SASIA A. "Effect of crusting operations on the mechanical properties of leather." Revista de Pielarie Incaltaminte. 2018;18:283. Abstract
Otsyina HR, Mbuthia PG, Nguhiu-Mwangi J, Mogoa EGM, Ogara WO. "Effect of ruminal plastic bags on haematological and biochemical parameters of sheep and goats." Ghana Journal of Agricultural Science. 2018;53:5-16. Abstract
Otsyina HR, Nguhiu-Mwangi J, Mogoa EGM, Mbuthia PG, Ogara WO. "Knowledge, attitude, and practices on usage, disposal, and effect of plastic bags on sheep and goats." Tropical animal health and production. 2018;50:997-1003. Abstract
Bhatt B, Kalambuka HAA, Dehayem-Kamadjeu A. "LIBS Development Methodology for Forensic Nuclear Materials Analysis." Analytical Methods. 2018. Abstract
Zipporah M, Robinson M, Julius M, Arti K. "Perpendicular magnetic anisotropy in Mn2VIn (001) films: An ab initio study." AIP Advances. 2018;8:055701. Abstract
Zipporah M, Robinson M, Julius M, Arti K. "Perpendicular magnetic anisotropy in Mn2VIn (001) films: An ab initio study." AIP Advances. 2018;8:055701. Abstract
Zipporah M, Robinson M, Julius M, Arti K. "Perpendicular magnetic anisotropy in Mn2VIn (001) films: An ab initio study." AIP Advances. 2018;8:055701. Abstract
Zipporah M, Robinson M, Julius M, Arti K. "Perpendicular magnetic anisotropy in Mn2VIn (001) films: An ab initio study." AIP Advances. 2018;8:055701. Abstract
Richter RS, Yaya A, Dodoo-Arhin D, Agyei-Tuffour B, Musembi RJ, Onwona-Agyeman B. "Preparation and Characterization of Indium and Gallium doped Transparent ZnO films for Solar cell Applications." Oriental Journal of Chemistry. 2018;34:2325-2331. Abstract
Bulle Hallo Dabasso, Oliver Vivian Wasonga PIBK. "Stratified cattle production in pastoral areas of Kenya: Existing forms, driving factors and management practices." Applied Animal Husbandry & Rural Development. 2018;11. Abstract
Muthui ZW, Musembi RJ, Mwabora JM, Skomski R, Kashyap A. "Structural, Electronic and Magnetic Properties of the Heusler Alloy Mn 2 VIn: A Combined DFT and Experimental Study." IEEE Transactions on Magnetics. 2018;54:1-5. Abstract
Muthui ZW, Musembi RJ, Mwabora JM, Skomski R, Kashyap A. "Structural, Electronic and Magnetic Properties of the Heusler Alloy Mn 2 VIn: A Combined DFT and Experimental Study." IEEE Transactions on Magnetics. 2018;54:1-5. Abstract
Muthui ZW, Musembi RJ, Mwabora JM, Skomski R, Kashyap A. "Structural, Electronic and Magnetic Properties of the Heusler Alloy Mn 2 VIn: A Combined DFT and Experimental Study." IEEE Transactions on Magnetics. 2018;54:1-5. Abstract
Willy E Mwangi, Eddy M Mogoa JMPMSMNGW. "A systematic review of analgesia practices in dogs undergoing ovariohysterectomy." Veterinary World. 2018;11:1725-1735. Abstract
Ondieki EO. "A need for new housing policies in an entrenched neoliberal economic environment in Sub- Sahara Africa." Africa Habitat Review Journal - . Nairobi, SBE Publication- UoN. 2017;Volume 11(. Nairobi, SBE Publication- UoN):Page 1147-1155.
Kanyinga K. "Presidential petition exposed counsel as largely poorly prepared for task." Sunday Nation, September 10, 2018.
Peter Akuon HX. "Gain of Spatial Diversity with Conjoint Signals.". In: IEEE Africon. Cape Town, South Africa; 2017.
Kanyinga K. "Election or no election, the country is more polarised than ever before." Sunday Nation, October 21, 2017.
Kanyinga K. "Uhuru and Raila should sit together, alone, and resolve to unite Kenya." Sunday Nation, October 8, 2017.
Kanyinga K. "Avert tendency of ending up with battered economy after every poll." Sunday Nation, November 18, 2017.
Kanyinga K. "Lessons from nominations." Sunday Nation, May 20, 2017.
Kanyinga K. "Nominations have ‘orphaned’ central and Nyanza regions." Sunday Nation, May 6, 2017.
Kanyinga K. "Vision forestalls war and keeps economy steady." Sunday Nation, March 25, 2017.
Kanyinga K. "Strengthening devolution will require a totally new mindset." Sunday Nation, March 11, 2017.
I M, A A, S M, C B, J W, E M, Onyango N, Nyagol J. Assessment of MNCH services provided by private health care providers in Kibra Sub-county of Nairobi County. . Nairobi: Kibra Private Health Care Providers Study Report; Ministry of Health Report, Kenya; 2017.
Kanyinga K. "Election risks plunging us deeper into tribal division." Sunday Nation, June 17, 2017.
Kanyinga K. "Tribal alliances will continue to affect electoral process." Sunday Nation, June 3, 2017.
Nyunja C, Maina J, Amimo J, Kibegwa F, Harper D, Junga J. "{Stock Structure Delineation of the African Catfish (Clarius gariepinus) in Selected Populations in Kenya Using Mitochondrial DNA (Dloop) Variability}." Journal of Aquaculture Research {&} Development. 2017;08. AbstractWebsite

This study genetically characterized five populations of the African catfish (Clarius gariepinus) in Kenya. Samples were obtained from five sites in the country–Athi River hatchery, Kisii Fingerling Production Centre (FPC), Jewlett hatchery, Sagana Hatchery Station and Lake Baringo. DNA was extracted from tissue samples, followed by amplification and sequencing of the dloop region. Haplotype diversities, phylogenetic structure and variation at the dloop region of mitochondrial DNA were assessed. Mitochondrial DNA analyses indicated that the sampled species showed genetic diversity between its populations. The genetic results were congruent indicating the differences in diversities and haplotype similarities of catfish samples from different sites. The Sagana, Kisii FPC, Jewlett and Baringo population cluster overlapped indicating possibly shared source of brood stock. The Athi river population was in a different cluster and its distinctiveness is attributed to imported brood stock. Both Athi River hatchery and Lake Baringo populations were highly variable and has great potential for production.

Kanyinga K. "Marginalisation’ no longer a presidential campaign issue." Sunday Nation, July 16, 2017.
Kanyinga K. "Marginalisation in Kenya: Origins, trends, and policy solutions.". In: Commission on Allocation of Revenue (CRA), Kenya. Nairobi; 2017.
Kanyinga K. "Manifestos rich on promises, vague on delivery strategies." Sunday Nation, July 1, 2017.
Kanyinga K. "Road to August election is bumpy." Sunday Nation, January 28, 2017.
Kanyinga K. "Why government and NGOs aren’t friends." Sunday Nation, January 15, 2017.
Kanyinga K. "A new political settlement is required in Kenya going to 2022." Sunday Nation, January 1, 2017.
Kanyinga K. "Election is about Kenya, not voter mapping." Sunday Nation, February 25, 2017.
Kanyinga K. "Good leadership in counties is an important condition for development." Sunday Nation, December 17, 2017.
Ondieki EO. "A need for new housing policies in an entrenched neoliberal economic environment in Sub- Sahara Africa." Africa Habitat Review Journal - . Nairobi, SBE Publication- UoN. 2017;Vol 11-2017(SBE Publication- UoN):Page 1147-1155).abstract_-_a_need_for_a_new_housing_policy_-aug2017.docx
Kanyinga K. "An open letter to governors: How to get quick wins in first three months." Sunday Nation, August 27, 2017.
Kanyinga K. "Voter rationality shaped poll outcome." Sunday Nation, August 13, 2017.
Olago D, Verschuren D, Daele MV, Wolff C, Waldmann N. "ICDP project DeepCHALLA: reconstructing East African climate change and environmental history over the past 250,000 years.". In: 19th EGU General Assembly, EGU2017. Vienna, Austria; 2017. Abstract

Sediments on the bottom of Lake Challa, a 92-meter deep crater lake on the border of Kenya and Tanzania near Mt. Kilimanjaro, contain a uniquely long and continuous record of past climate and environmental change. The near-equatorial location and exceptional quality of this natural archive provide great opportunities to study tropical climate variability at both short (inter-annual to decadal) and long (glacial-interglacial) time scales; and the influence of this climate variability on the region's freshwater resources, the functioning of terrestrial ecosystems, and the history of the East African landscape in which modern humans (our species, Homo sapiens) evolved and have lived ever since. Supported in part by the International Continental Scientific Drilling Programme (ICDP), the DeepCHALLA project has now recovered the sediment record of Lake Challa down to 214.8 meter below the lake floor, with almost certain 100% cover of the uppermost 121.3 meter (ca.150,000 year BP to present) and estimated 85% cover over the lower part of the sequence, down to the lowermost distinct reflector in the available seismic stratigraphy. This reflector represents a 2 meter thick layer of volcanic sand and silt deposited ca.250,000 years ago, and overlies still older silty lacustrine clays deposited during early lake development. Down-hole logging produced continuous profiles of in-situ sediment composition that confer an absolute depth scale to both the recovered cores and their three-dimensional representation in seismic stratigraphy. As readily observed through the transparent core liners, Lake Challa sediments are finely laminated throughout most of the recovered sequence. Combined with the great time span, the exquisite temporal resolution of these sediments promises to greatly increase our understanding of tropical climate and ecosystem dynamics, and create a long-awaited equatorial counterpart to the high-latitude climate records extracted from the ice sheets of Greenland and Antarctica.

Kanyinga K. "Agriculture can help uproot poverty." Sunday Nation, April 22, 2017.
Gureya D, Barreto J. "Profiling for Asymmetric NUMA Systems.". In: 11th EuroSys Doctoral Workshop (EuroDW'17). Belgrade, Serbia; 2017. Abstract


Upadhyaya R. "The Politics of High Level of Adoption of Global Banking Standars in Kenya: "A Case of Alignment of Donor, Government and Banking Sector Interests".". In: Second Annual Workshop - LICs Navigating Global Banking Standards. Blavatnik School of Government, University of Oxford; 2017.
Ngaruiya N, Orwa D, Waiganjo P. "Towards a Deployment Model for eMonitoring of Geriatric Persons in Rural Developing Countries: Case of Kenya.". In: Vol. 1. Namibia; 2017. Abstract

The United Nations and the African Union considers a person aged 65
years and above as a geriatric person. The graying population over the past decades
is showing an exponential growth rate compared to the declining fertility rate. This
population in the developing countries is not boastful of active ageing (successful,
independent ageing) as they are challenged by various health issues and
psychosomatic conditions. They require constant care and in some cases, specialized
care in familiar environments (their homes with relatives) or nursing homes (called
Nyumba za Wazee in Kenya). The researchers with support from literature believe
that technology can offer this specialized care (E-monitoring). This would be offered
in the comfort of their homes through continuous assessment of the geriatric person
relaying information to both the formal and informal caregivers. The objective of this
paper is to explore, summarize and analyse the various technologies in gerontology,
acceptance and adoption models, with the aim of identifying a suitable deployment
model that could be adopted in the context of a developing country.

Mutuma WK. "The role of national courts in furthering the development of international humanitarian law.". In: Conference Paper, ICRC, 5th Regional Implementation Seminar for Researchers. Nairobi; 2017.
LNW, Njogu REN, Kariuki DK, Yusuf AO, Wendt OF. "”Synthesis of Tris Cyclometalated Iridium (III) Complexes under Green Conditions for Photoredox Catalysis” Trends in Green Chemistry.". In: Trends in Green Chemistry. Stockholm University; 2017.
Kante M, Chepken C, Oboko R. "Methods for translating ICTs’ survey questionnaire into French and Bambara.". In: Egerton University, 11th international conference. Njoro, Kenya; 2017. Abstract

Researchers have used many instruments to gather data on the use of Information and
Communication Technology to disseminate information on agricultural inputs towards farmers.
These instruments are in English and based on some theories. The Technology Acceptance Model
(TAM), the Diffusion of Innovation Theory (DOI) and the Unified Theory of Acceptance and Use of
Technology (UTAUT) are the three most popular contemporary technology acceptance models. For
other speaking languages especially French and Bambara, there is a need to translate. The increasing
need for non-English data collection instruments and other survey materials has clearly given recent
figures. Despite the availability of tools for translation, the DOI’s instrument has been barely
translated into French and Bambara. In this paper, we used an adaptation method to translate the
DOI’s instrument into French and Bambara. We produced a method for translating English survey
questionnaire into French and Bambara. The method specifies and describes five steps, which are
prepare, translate, pretest, revise and document.
Keywords: ICT, Agriculture, Translation, French, Bambara

Karuga SW, GATARI MJ, Kelder EM, Marijnissen JCM. "Solid-state electrolytes for lithium ion batteries: Application of Electrospray technique.". In: European Aerosol Conference. Zurich, Switzerland; 2017.
Kirui G, Gakuya DW, Abuom TO. "Challenges in food animal practice in the urban areas- Nairobi City and its environs.". In: The Kenya Veterinary Association, Commonwealth Veterinary Association and university Nairobi, Faculty of Veterianry Medicine Joint Scientific Conference. Safari Park Hotel, Nairobi, Kenya; 2017.
"10th Anniversary workshop of the Understanding Development Issues in Nurse Educator (UDINE-C) network and the health educators East Midlands celebrations conference,.". In: 10th Anniversary workshop of the Understanding Development Issues in Nurse Educator (UDINE-C) network and the health educators East Midlands celebrations conference,. Lincoln, UK; 2017.
Mugambi JNK. "Why Water: Lenten Meditation for 2017 World Water Day.". In: ”, Ecumenical Water Network. Geneva; 2017.
Marangu D, Mwaniki H, Nduku S, Maleche-Obimbo E, Jaoko W, Babigumira J, John-Stewart G, Rao D. "ADAPTING A STIGMA SCALE FOR ASSESSMENT OF TUBERCULOSIS-RELATED STIGMA AMONG ENGLISH/SWAHILI-SPEAKING PATIENTS IN AN AFRICAN SETTING." Stigma Health. 2017;2(4):326. Abstract

To adapt a validated instrument that quantitatively measures stigma among English/Swahili speaking TB (tuberculosis) patients in Kenya, a high burden TB country.

Lokken EM, Balkus JE, Kiarie J, Hughes JP, Jaoko W, Totten PA, McClelland SR, Manhart LE. "Recent bacterial vaginosis is associated with acquisition of Mycoplasma genitalium." Am. J. Epidemiol.. 2017. Abstract

We assessed the association between recent bacterial vaginosis (BV) and incident Mycoplasma genitalium, a sexually transmitted bacterium associated with adverse female reproductive health outcomes. Female sex workers in Mombasa, Kenya completed a monthly sexual behavior interview and clinical examination. During February 2005-February 2006, vaginal fluid specimens collected from women every other month were tested for M. genitalium by nucleic acid amplification testing. Vaginal microbiota was assessed monthly and categorized by Nugent score (0-3 normal, 4-6 intermediate microbiota, 7-10 BV). A discrete time failure analysis for multiple events using logistic regression was used to estimate the odds of incident M. genitalium infection at follow-up visits in women with BV versus normal microbiota at the preceding visit. Among the 280 women, 54.3% were HIV positive. At baseline, 16.1% had prevalent M. genitalium infections and 40.4% had prevalent BV. There were 59 incident M. genitalium infections among 50 women for an incidence rate of 34.6 per 100 person-years. Following adjustment for age, HIV status, and time, prior BV was associated with a 3.5-fold increase in odds of incident M. genitalium (adjusted odds ratio = 3.49; 95% confidence interval: 1.86, 6.56). This strong association suggests that BV may enhance susceptibility to M. genitalium infection.

Otange BO, Birech Z, Okonda J, Rop R. "Conductive silver paste smeared glass substrates for label-free Raman spectroscopic detection of HIV-1 and HIV-1 p24 antigen in blood plasma." Anal Bioanal Chem. 2017;409(12):3253-3259. Abstract

We report on application of conductive silver paste smeared glass slides as Raman spectroscopy sample substrates for label-free detection of HIV-1 p24 antigen in blood plasma. We also show that the same substrates can be applied in Raman spectroscopic screening of blood plasma for presence of HIV. The characteristic Raman spectrum of HIV-1 p24 antigen displayed prominent bands that were assigned to ribonucleic acids (RNA) and proteins that constitute the antigen. This spectrum can be used as reference during Raman spectroscopic screening for HIV in plasma within the first few days after exposure (<7 days). The Raman spectra obtained from HIV+ plasma displayed unique peaks centered at wavenumbers 928, 990, 1270, 1397, and 1446 cm(-1) attributed to the Raman active vibrations in the virion carbohydrates, lipids, and proteins. Other bands similar to those reported in literature were also seen and assignments made. The attachment of the HIV virions to silver nanoparticles via gp120 glycoprotein knobs was thought to be responsible for the enhanced Raman signals of proteins associated with the virus. The principal component analysis (PCA) applied on the combined spectral data showed that HIV- and HIV+ spectra had differing spectral patterns. This indicated the great power of Raman spectroscopy in HIV detection when plasma samples are deposited onto silver paste smeared glass substrates. The Raman peaks responsible for the segregation of the spectral data in PCA were mainly those assigned to the viral proteins (645, 725, 813, 1270, and 1658 cm(-1)). Excellent results were obtained from Artificial Neural Network (ANN) applied on the HIV+ Raman spectral data around the prominent peak centered at 1270 cm(-1) with R (coefficient of correlation) and R (2) (coefficient of determination) values of 0.9958 and 0.9895, respectively. The method has the potential of being used as quick blood screening for HIV before blood transfusion with the Raman peaks assigned to the virion proteins acting as reference. Graphical Abstract The HIV type 1 virus particle gets attached to the silver nanoparticle contained in the conductive silver paste smear onto a glass slide. This results in strong Raman signals associated with the components of the virion. The signals are collected, dispersed in a spectrometer and displayed on a computer screen. Method can be used as a label-free and rapid HIV screening in blood plasma.

Vlasova AN, Amimo JO, Saif LJ. "Porcine Rotaviruses: Epidemiology, Immune Responses and Control Strategies." Viruses. 2017;9(3). Abstract

Rotaviruses (RVs) are a major cause of acute viral gastroenteritis in young animals and children worldwide. Immunocompetent adults of different species become resistant to clinical disease due to post-infection immunity, immune system maturation and gut physiological changes. Of the 9 RV genogroups (A-I), RV A, B, and C (RVA, RVB, and RVC, respectively) are associated with diarrhea in piglets. Although discovered decades ago, porcine genogroup E RVs (RVE) are uncommon and their pathogenesis is not studied well. The presence of porcine RV H (RVH), a newly defined distinct genogroup, was recently confirmed in diarrheic pigs in Japan, Brazil, and the US. The complex epidemiology, pathogenicity and high genetic diversity of porcine RVAs are widely recognized and well-studied. More recent data show a significant genetic diversity based on the VP7 gene analysis of RVB and C strains in pigs. In this review, we will summarize previous and recent research to provide insights on historic and current prevalence and genetic diversity of porcine RVs in different geographic regions and production systems. We will also provide a brief overview of immune responses to porcine RVs, available control strategies and zoonotic potential of different RV genotypes. An improved understanding of the above parameters may lead to the development of more optimal strategies to manage RV diarrheal disease in swine and humans.

Buttolph J, Inwani I, Agot K, Cleland CM, Cherutich P, Kiarie JN, Osoti A, Celum CL, Baeten JM, Ruth Nduati, John Kinuthia, James N Kiarie, Hallett TB, Alsallaq R, Kurth AE. "Gender-Specific Combination HIV Prevention for Youth in High-Burden Settings: The MP3 Youth Observational Pilot Study Protocol." JMIR Res Protoc. 2017;6(3):e22. Abstract

Nearly three decades into the epidemic, sub-Saharan Africa (SSA) remains the region most heavily affected by human immunodeficiency virus (HIV), with nearly 70% of the 34 million people living with HIV globally residing in the region. In SSA, female and male youth (15 to 24 years) are at a disproportionately high risk of HIV infection compared to adults. As such, there is a need to target HIV prevention strategies to youth and to tailor them to a gender-specific context. This protocol describes the process for the multi-staged approach in the design of the MP3 Youth pilot study, a gender-specific, combination, HIV prevention intervention for youth in Kenya.

Balkus JE, Srinivasan S, Anzala O, Kimani J, Andac C, Schwebke J, Fredricks DN, McClelland SR. "Impact of Periodic Presumptive Treatment for Bacterial Vaginosis on the Vaginal Microbiome among Women Participating in the Preventing Vaginal Infections Trial." J. Infect. Dis.. 2017;215(5):723-731. Abstract

Evidence suggests that specific vaginal bacteria associated with bacterial vaginosis (BV) may increase the risk of adverse health outcomes in women. Among women participating in a randomized, double-blinded trial, we assessed the effect of periodic presumptive treatment (PPT) on detection of select vaginal bacteria.

Bork KA, Cames C, Newell M-L, Read JS, Ayassou K, Musyoka F, Mbatia G, Cournil A. "Formula-Feeding of HIV-Exposed Uninfected African Children Is Associated with Faster Growth in Length during the First 6 Months of Life in the Kesho Bora Study." J. Nutr.. 2017;147(3):453-461. Abstract

Background: Early feeding patterns may affect the growth of HIV-exposed children and thus their subsequent health and cognition.Objective: We assessed the association of infant feeding (IF) mode with length-for-age z score (LAZ) and stunting from age 2 d to 18 mo in HIV-exposed African children within a controlled randomized trial, which evaluated triple antiretrovirals initiated during pregnancy and continued for 6 mo postpartum to prevent HIV transmission.Methods: HIV-infected pregnant women with CD4(+) counts of 200-500 cells/mm(3) from Burkina Faso, Kenya, and South Africa were advised to exclusively breastfeed for up to 6 mo or to formula-feed from birth. Factors associated with LAZ were investigated in all uninfected children by using mixed-effects linear models; those associated with stunting (LAZ <-2) at 6 or 12 mo were assessed in multiple logistic regression after exclusion of children stunted at age 2 d. Independent variables were IF mode: formula feeding (FF), exclusive breastfeeding (EBF) <3 mo, or EBF ≥3 mo (reference); sex; trial arm; maternal characteristics; and site.Results: Among 728 children, FF was associated with a greater increase in LAZ from 2 d to 6 mo (+0.07 z score/mo, P < 0.001). Between 6 and 18 mo, FF and EBF <3 mo were both associated with greater mean LAZ than was EBF ≥3 mo (+0.52 z scores and +0.43 z scores, respectively, P < 0.001). Among children not stunted at 2 d, FF was independently associated with a reduced risk of stunting at 6 mo (OR: 0.24; 95% CI: 0.07, 0.81; P = 0.021), whereas EBF <3 mo was not (OR: 0.49; 95% CI: 0.22, 1.10; P = 0.09).Conclusions: In this observational study of HIV-exposed uninfected infants, growth in length in the first 6 mo of life was faster in formula-fed infants than in exclusively breastfed infants. The plausibility of residual confounding and reverse causality is discussed. This trial was registered at as ISRCTN71468401.

Wall KM, Rida W, Haddad LB, Kamali A, Karita E, Lakhi S, Kilembe W, Allen S, Inambao M, Yang AH, Latka MH, Anzala O, Sanders EJ, Bekker L-G, Edward VA, Price MA. "Pregnancy and HIV Disease Progression in an Early Infection Cohort from Five African Countries." Epidemiology. 2017;28(2):224-232. Abstract

Understanding associations between pregnancy and HIV disease progression is critical to provide appropriate counseling and care to HIV-positive women.

Gichuhi S, Kabiru J, Zindamoyen AM'bongo, Rono H, Ollando E, Wachira J, Munene R, Onyuma T, Sagoo MS, Macleod D, Weiss HA, Burton MJ. "Delay along the care-seeking journey of patients with ocular surface squamous neoplasia in Kenya." BMC Health Serv Res. 2017;17(1):485. AbstractWebsite


In Africa, accessing eye health services is a major challenge. Ocular surface squamous neoplasia (OSSN) is a substantial ocular health problem in Africa related to solar UV light exposure and HIV infection among other risk factors. The disease causes visual loss and even death in advanced cases. This study was conducted to assess referral pathway and treatment delay for patients with OSSN in Kenya.

Adults with conjunctival lesions presenting to four eye centres were asked about their occupations, when they noticed the growth, health facilities visited in seeking care, cost of consultation, surgery, medicines and histopathology and dates at each step. The time-to-presentation was divided into quartiles and correlates analysed using ordinal logistic regression.

We evaluated 158 first-time presenters with OSSN. Most were women (102 [65%]), living with HIV (78/110 tested [71%]), with low to medium income (127 [80%]). Most of the HIV patients (49/78 [63%]) were in antiretroviral care programs. About half (88/158, [56%]) presented directly to the study centres while the rest were referred. Indirect presenters sought care earlier than direct presenters (median 2.0 months vs 5.5 months) and travelled a shorter distance to the first health facility (median 20 km vs 30 km) but had surgery later (median 12.5 months vs 5.5 months). Visits beyond the first health facility for indirect presenters markedly increased delay (median 7.3, 29.0, 37.9, and 32.0 months for 1-4 facilities, respectively). Delay was associated with number of health facilities visited (adjusted ordered OR = 9.12; 95%CI 2.83-29.4, p < 0.001) and being female (adjusted ordered OR = 2.42; 95%CI 1.32-4.44, p = 0.004). At the time of presentation at the study centres for surgery the median tumour diameter in both directly and indirectly presenting patients was 6 mm (p = 0.52) and the histological spectrum of OSSN was similar between the groups (p = 0.87).

Referral delays definitive treatment for OSSN. Women were more likely to experience delay. Despite regular contact with the health system for those with known HIV infection, delays occurred. Early detection and referral of OSSN in the HIV service might reduce delays, but reassuringly delay did not give rise to a larger proportion with more advanced grade of OSSN.

Nyombayire J, Anzala O, Gazzard B, Karita E, Bergin P, Hayes P, Kopycinski J, Omosa-Manyonyi G, Jackson A, Bizimana J, Farah B, Sayeed E, Parks CL, Inoue M, Hironaka T, Hara H, Shu T, Matano T, Dally L, Barin B, Park H, Gilmour J, Lombardo A, Excler J-L, Fast P, Laufer DS, Cox JH. "First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus-Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens." J. Infect. Dis.. 2017;215(1):95-104. Abstract

 We report the first-in-human safety and immunogenicity assessment of a prototype intranasally administered, replication-competent Sendai virus (SeV)-vectored, human immunodeficiency virus type 1 (HIV-1) vaccine.

Okaru AO, Abuga KO, Kamau FN, Ndwigah SN, Lachenmeier DW. "A Robust Liquid Chromatographic Method for Confirmation of Drug Stability of Azithromycin in Bulk Samples, Tablets and Suspensions." Pharmaceutics. 2017;9(1). Abstract

A simple, isocratic and robust RP-HPLC method for the analysis of azithromycin was developed, validated and applied for the analysis of bulk samples, tablets and suspensions. The optimum chromatographic conditions for separation were established as a mobile phase comprised of acetonitrile-0.1 M KH₂PO₄ pH 6.5-0.1 M tetrabutyl ammonium hydroxide pH 6.5-water (25:15:1:59 v/v/v/v) delivered at a flow rate of 1.0 mL/min. The stationary phase consisted of reverse-phase XTerra(®) (250 mm × 4.6 mm i.d., 5 µm particle size) maintained at a temperature of 43 °C with a UV detection at 215 nm. The method was found to be linear in the range 50%-150% (r² = 0.997). The limits of detection and quantification were found to be 0.02% (20 µg) and 0.078% (78 µg), respectively, with a 100.7% recovery of azithromycin. Degradation products of azithromycin in acidic and oxidative environments at 37 °C were resolved from the active pharmaceutical ingredient and thus the method is fit for the purpose of drug stability confirmation.

Newman LP, Njoroge A, Magaret A, Chohan BH, Gitomea VW, Wald A, Gorstein J, Overbaugh J, Dalton Wamalwa, Maleche-Obimbo E, Ruth Nduati, Farquhar C. "Sustained Responses to Measles Revaccination at 24 Months in HIV-Infected Children on Antiretroviral Therapy in Kenya." Pediatr. Infect. Dis. J.. 2017. Abstract

There are limited data on whether HIV-infected children in resource-limited countries who are receiving antiretroviral therapy (ART) are able to produce sustained, protective levels of measles antibody after multiple measles vaccinations.

Goyette MS, Wilson KS, Deya R, Masese LN, Shafi J, Richardson BA, Mandaliya K, Jaoko W, McClelland SR. "Brief Report: Association Between Menopause and Unprotected Sex in High-Risk HIV-Positive Women in Mombasa, Kenya." J. Acquir. Immune Defic. Syndr.. 2017;74(5):488-492. Abstract

Many HIV-positive women now live well beyond menopause. Postmenopausal women are no longer at risk for pregnancy, and some studies suggest that they may use condoms less often than premenopausal women. This study tests the hypothesis that, in HIV-positive women who report trading sex for cash or in-kind payment, unprotected sex is more common at postmenopausal visits compared with premenopausal visits.

Ronen K, Dingens AS, Graham SM, Jaoko W, Mandaliya K, McClelland SR, Overbaugh J. "Comprehensive Characterization of Humoral Correlates of Human Immunodeficiency Virus 1 Superinfection Acquisition in High-risk Kenyan Women." EBioMedicine. 2017;18:216-224. Abstract

HIV-1 superinfection, in which an infected individual acquires a second HIV-1 infection from a different partner, is one of the only settings in which HIV acquisition occurs in the context of a pre-existing immune response to natural HIV infection. There is evidence that initial infection provides some protection from superinfection, particularly after 6months of initial infection, when development of broad immunity occurs. Comparison of the immune response of superinfected individuals at the time of superinfection acquisition to that of individuals who remain singly infected despite continued exposure can shed light on immune correlates of HIV acquisition to inform prophylactic vaccine design. We evaluated a panel of humoral immune responses in the largest published group of superinfected individuals (n=21), compared to a set of 3:1 matched singly infected controls from the same cohort. The immune functions studied included plasma neutralization, plasma and cervical antibody-dependent cellular cytotoxicity, and plasma IgG and IgA binding to a panel of 18 envelope antigens, including correlates of HIV acquisition in the RV144 vaccine trial, IgG binding to V1V2 and IgA binding to gp140. Association between each immune function and HIV superinfection was evaluated using conditional logistic regression. No significant associations were detected between any of the immune functions and superinfection acquisition. This study constitutes the most comprehensive and detailed characterization of multiple immune correlates of superinfection to date. The results suggest that immune responses not commonly measured in current HIV studies may be important in protection from HIV infection, and these or a more robust humoral response than that seen in naturally infected women may be needed for a protective vaccine.

Nordstrom MPC, Westercamp N, Jaoko W, Okeyo T, Bailey RC. "Medical Male Circumcision Is Associated With Improvements in Pain During Intercourse and Sexual Satisfaction in Kenya." J Sex Med. 2017;14(4):601-612. Abstract

Two cohort studies using data from randomized controlled trials in Africa offer the best evidence to date on the effects of voluntary medical male circumcision (VMMC) on male sexual function and satisfaction, suggesting no significant impairments in sexual function or satisfaction and some improvements in sexual function after male circumcision.

Dziuban EJ, DeVos J, Ngeno B, Ngugi E, Zhang G, Sabatier J, Wagar N, Diallo K, Nganga L, Katana A, Yang C, Rivadeneira ED, Mukui I, Odhiambo F, Redfield R, Raizes E. "High Prevalence of Abacavir-associated L74V/I Mutations in Kenyan Children Failing Antiretroviral Therapy." Pediatr. Infect. Dis. J.. 2017;36(8):758-760. Abstract

A survey of 461 HIV-infected Kenyan children receiving antiretroviral therapy found 143 (31%) failing virologically. Drug resistance mutations were found in 121; 37 had L74V/I mutations, with 95% receiving abacavir (ABC)-containing regimens. L74V/I was associated with current ABC usage (P = 0.0001). L74V/I may be more prevalent than previously realized in children failing ABC-containing regimens, even when time on treatment has been short. Ongoing rigorous pediatric drug resistance surveillance is needed.

Oiye S, Mwanda W, Mugambi M, Filteau S, Owino V. "Exclusive Breastfeeding Is More Common Among HIV-Infected Than HIV-Uninfected Kenyan Mothers at 6 Weeks and 6 Months Postpartum." Breastfeed Med. 2017;12:283-289. Abstract

To compare breastfeeding practices determined by mothers' own recall versus a stable isotope technique (deuterium oxide dilution) among human immunodeficiency virus (HIV)-infected and HIV-uninfected mothers at 6 weeks and 6 months postpartum.

Birech Z, Mwangi PW, Bukachi F, Mandela KM. "Application of Raman spectroscopy in type 2 diabetes screening in blood using leucine and isoleucine amino-acids as biomarkers and in comparative anti-diabetic drugs efficacy studies." PLoS ONE. 2017;12(9):e0185130. Abstractapplication_of_raman_spectroscopy_in_type_2_journal.pone_.0185130.pdf

Diabetes is an irreversible condition characterized by elevated blood glucose levels. Currently, there are no predictive biomarkers for this disease and the existing ones such as hemoglobin A1c and fasting blood glucose are used only when diabetes symptoms are noticed. The objective of this work was first to explore the potential of leucine and isoleucine amino acids as diabetes type 2 biomarkers using their Raman spectroscopic signatures. Secondly, we wanted to explore whether Raman spectroscopy can be applied in comparative efficacy studies between commercially available anti-diabetic drug pioglitazone and the locally used anti-diabetic herbal extract Momordica spinosa (Gilg.)Chiov. Sprague Dawley (SD) rat's blood was used and were pipetted onto Raman substrates prepared from conductive silver paste smeared glass slides. Prominent Raman bands associated with glucose (926, 1302, 1125 cm-1), leucine (1106, 1248, 1302, 1395 cm-1) and isolecucine (1108, 1248, 1437 and 1585 cm-1) were observed. The Raman bands centered at 1125 cm-1, 1395 cm-1 and 1437 cm-1 associated respectively to glucose, leucine and isoleucine were chosen as biomarker Raman peaks for diabetes type 2. These Raman bands displayed decreased intensities in blood from diabetic SD rats administered antidiabetic drugs pioglitazone and herbal extract Momordica spinosa (Gilg.)Chiov. The intensity decrease indicated reduced concentration levels of the respective biomarker molecules: glucose (1125 cm-1), leucine (1395 cm-1) and isoleucine (1437 cm-1) in blood. The results displayed the power and potential of Raman spectroscopy in rapid (10 seconds) diabetes and pre-diabetes screening in blood (human or rat's) with not only glucose acting as a biomarker but also leucine and isoleucine amino-acids where intensities of respectively assigned bands act as references. It also showed that using Raman spectroscopic signatures of the chosen biomarkers, the method can be an alternative for performing comparative efficacy studies between known and new anti-diabetic drugs. Reports on use of Raman spectroscopy in type 2 diabetes mellitus screening with Raman bands associated with leucine and isoleucine molecules acting as reference is rare in literature. The use of Raman spectroscopy in pre-diabetes screening of blood for changes in levels of leucine and isoleucine amino acids is particularly interesting as once elevated levels are noticed, necessary interventions to prevent diabetes development can be initiated.

Tamimi IFM, Patel NB. "Open field ethogram and olfactory preference in naked mole rat (Heterocephalus glabus). .". In: Society of Neuroscientists of Africa. Entebbe, Uganda; 2017.imaan_-_sona_poster__27_may_2017.pdf
Marangu D, Mwaniki H, Nduku S, Maleche-Obimbo E, Jaoko W, Babigumira J, John-Stewart G, Rao D. "Stakeholder perspectives for optimization of tuberculosis contact investigation in a high-burden setting." PLoS ONE. 2017;12(9):e0183749. Abstract

Optimal tuberculosis contact investigation impacts TB prevention, timely case finding and linkage to care, however data on routine implementation in high burden contexts is limited.

Amimo JO, Otieno TF, Okoth E, Onono JO, Bett B. "Risk factors for rotavirus infection in pigs in Busia and Teso subcounties, Western Kenya." Trop Anim Health Prod. 2017;49(1):105-112 . Abstract

We analysed data that were previously collected for molecular characterisation of rotavirus (RV) groups A and C in pigs from Teso and Busia subcounties in Kenya to determine risk factors for its infection. The data included records from 239 randomly selected piglets aged between 1 and 6 months raised in free range and backyard production systems. RV infection was confirmed by screening of fresh faecal samples by using reverse transcription polymerase chain reaction (RT-PCR); selected positive samples were subsequently sequenced and used for phylogenetic analysis. In this analysis, RV infection status was used as outcome variable, while the metadata collected at the time of sampling were used as predictors. A Bayesian hierarchical model which used integrated nested Laplace approximation (INLA) method was then fitted to the data. The model accounted for the spatial effect by using stochastic partial differential equations (SPDEs). Of the 239 samples screened, 206 were available for the analysis. Descriptive analyses showed that 27.7 % (57/206) of the samples were positive for rotaviruses groups A and C, 18.5 % were positive for group A rotaviruses, 5.3 % were positive for group C rotaviruses, while 3.9 % had co-infections from both groups of rotaviruses. The spatial effect was insignificant, and a simple (non-spatial) model showed that piglets (≤4 months) and those pigs kept in free range systems had higher risk of exposure to rotavirus infection as compared to older pigs (>4 months) and those tethered or housed, respectively. Intervention measures that will target these high-risk groups of pigs will be beneficial to farmers.

Mitema A, Rafudeen S, Okoth S, Iyer R. "Heterokaryon incompatibility and phenotypic characterisation of Aspergillus flavus isolates in low and high risk zones in Kenya.". In: The 14th International Aspergillus Meeting Asperfest 14. Asilomar Conference Center, PG, CA, USA; 2017.
Steven Awino, Afullo A. "Analytic BER of OFDM Powerline Communication at different IAT of Impulsive Noise.". In: SAUPEC. StellenBosch, South Africa; 2017.
Odhiambo JA, Lukhoba CW, Dossaji SF. "Corms as an additional feature to identify Gladiolus spp.". In: XXI AETFAT congress.; 2017. Abstractuse_of_corms_as__additional_features_to_identify.ppt

Gladiolus is a genus that consists of underground corms and strikingly showy flowers. The corms are mostly rounded and symmetrical enveloped with fibrous tunics. Presently the main and sure way to identify these plants is by their use of showy flowers; however, this becomes a challenge in during the dry seasons when the plants don’t flower. This study investigated the use of corms as additional feature for identification of Gladiolus species found in Kenya; Gladiolus watsonoides, G. goetzenii, G. ukambanensis and G. newii. Physical and histological features of the corms were evaluated according to Rolls, 2011, to investigate any differences across the different species. Although the analysis of the cells of corms did not reveal any obvious differences, their outward morphologies including the colour, shape and texture of the tunics were different across the species investigated. Therefore, corms form an additional feature of taxonomic value for identification and collection of these plants in the absence of flowers.
Key words: Gladiolus, Corms, Identification

Musila FM, Lukhoba CW, Dossaji SF, Nguta JM. "Molecular Phylogeny of ten Kenyan Plectranthus species in the Coleus clade.". In: XXI AETFAT congress. Catholic University of Eastern Africa, Nairobi, Kenya; 2017. Abstractaetfat_2017-fredrick_m.ppt

Plectranthus is one important genus of flowering plants whose member species have a variety of uses in the horticultural and in the medical field. Plectranthus species are difficult to distinguish morphologically and many species have been given different names by different authors. Use of morphological characters is not sufficiently enough to delimit the genus successfully. Molecular, anatomical and biochemical markers are better in studying interspecific variation compared to gross morphological markers. So far no study on molecular phylogeny of the Kenyan Plectranthus species has been conducted. By comparing the same gene sequence across species within a genus, a phylogenetic tree can be constructed which can support or give new insights into the existing classification and rule out the confusion brought by synonymy. As a result, the current study used molecular characters to classify ten Plectranthus species in the Coleus clade within the Plectranthus genus. The molecular characters used in the study were DNA sequences of two chloroplast genes: MatK and Rbcl genes considered as universal molecular markers. Genomic DNA from the ten species was obtained followed by amplification and sequencing of the two genes in each species. From the results, a phylogenetic tree reconstructed using MatK genes groups P. caninus, P. otostegioides, P. barbatus and P. lanuginosus together and all the four species form a monophyletic group. These four species together with P.aegyptiacus form a larger monophyletic group. The same pattern can be observed in the phylogenetic tree created using the Rbcl genes. Again based on the MatK genes; P. pseudomarruboides, P. ornatus, P. montanous and P. amboinicus have been showed to be closely related and are monophyletic. Again these four species together with P.edulis form a larger monophyletc group. This close relationship of these species can also be observed in phylogenetic tree produced using the Rbcl genes. The present study has grouped the ten study Plectranthus species using molecular characters into phylogenies which are supported by previous studies and proved that molecular characters can aid in plant identification and phylogenetic studies.
Key words; Plectranthus, Molecular phylogeny, MatK gene, Rbcl gene.

Olali T. "" A Critical Exposition of Jihad Trope as a Religious Philosophy in the Epic of Rasi'l Ghuli (1850-1855).". In: African Literature Association. Yale University, New Haven, Connecticut; 2017.
Birkin F, Ramos M, Makunda C, Margerison J, Polesie T, Balanzo A. "Revising the ontological status of traditional modes of living: The concepts and their practical consequences in sustainability issues in China, Kenya, Colombia and Sweden.". In: The 23rd International Sustainable Development Research Society (ISDRS) Conference. Bogota, Colombia; 2017.
Kimeu M. "Sustainable Design: Environmental Issues in Construction in Kenya.". In: The Board of Registration of Architects and Quantity Surveyors Professional Examination Candidates Training. Central Examination Centre, Chiromo Campus, University of Nairobi.; 2017.
Lydia W. Njenga, Rachael E.N. Njogu, Kariuki DK, Yusuf AO, Wendt OF. "Tris-Cyclometalated Iridium (III) Complexes as Photoredox Catalysts in Organic Synthesis.". In: Oorgandagarna - Inorganic Days,. Nynäshamn, Sweden; 2017.
Kilekwang L, Patel NB. "Catha edulis Forsk (khat) induces conditioned place preference in mice.". In: Society of Neuroscientists of Africa.; 2017.cpp_poster.pdf
WAITA SEBASTIAN, Aduda B. "Structural and Optical Characterization of Polymer based TiO2 films for Photovoltaic Applications.". In: Solar World Congress, 2017. Abu Dhabi, United Arab Emirates; 2017.
Kanyinga K. "Kenya and the August 2017 elections: A review of Key Drivers.". In: Commonwealth Foundation International Observers . Kenya; 2017.
Ndohvu JB. " African Values and Children's Rights Instruments.". In: In Jackson Wafula Muyila (Ed),African Values and the Rights of the Child: Challenges and Prospects. Saarbrucken: Editions Universitaires Europeennes; 2017.
M KP. " Influence of Legal Framework in Enhancing Democratic Governance Process in Kenya." Journal of Public Policy & Governance . 2017;1(2):43-57.
" Quality primary education in Kenya: Implications of teachers’ characteristics. ." European Journal of Education Studies. 2017;3(8):635-650.
Odada E, Zalasiewicz J, Williams M, Waters CN, Barnosky AD, et al. " Scale and diversity of the physical technosphere: A geological perspective." The Anthropocene Review. 2017;4(1):9-22. AbstractFull Text

We assess the scale and extent of the physical technosphere, defined here as the summed material output of the contemporary human enterprise. It includes active urban, agricultural and marine components, used to sustain energy and material flow for current human life, and a growing residue layer, currently only in small part recycled back into the active component. Preliminary estimates suggest a technosphere mass of approximately 30 trillion tonnes (Tt), which helps support a human biomass that, despite recent growth, is ~5 orders of magnitude smaller. The physical technosphere includes a large, rapidly growing diversity of complex objects that are potential trace fossils or ‘technofossils’. If assessed on palaeontological criteria, technofossil diversity already exceeds known estimates of biological diversity as measured by richness, far exceeds recognized fossil diversity, and may exceed total biological diversity through Earth’s history. The rapid transformation of much of Earth’s surface mass into the technosphere and its myriad components underscores the novelty of the current planetary transformation.

Onsomu Z, Kaijage E, Aduda J, Iraya C. "), Demographics and Investor Biases at the Nairobi Securities Exchange, Kenya." International Journal of Arts and Commerce. 2017;6(15):51-60.
Cherotich, M.G., Kalai, J.M., Kebenei PJ, Rose A. "). Prospects of Deputy Principals’ professional preparation on administrative tasks in boarding public secondary schools inBomet County, Kenya." The Cradle of Knowledge African Journal of educational and Social Science Research. 2017;5(2):109-117.
Mumma-Martinon CA. ". A brief on Total in Exploration & Production( Page 74) .". In: 60 Years of Total in Kenya: Celebrating 60 Years of Service . Nairobi : Total Kenya; 2017.
Jimmy ML, Nzuve F, Flourence O, Manyasa E, Muthomi J. ". Genetic variability, heritability, genetic advance and trait correlations in selected sorghum (Sorghum bicolor L. Moench) varieties." International Journal of Agronomy and Agricultural Research. 2017;11(5):47-56.
Opanga SA, Mwang’ombe NJ, Okalebo FA, Kuria KAM. ". Impact of neurosurgical site infections on patient expenditure at a national referral hospital in Kenya: a cost of illness study. ." African Journal of Pharmacology and Therapeutics. 2017;6(2):72-76.
Ngowi BV, Tonnang HEZ, Khamis F, Mwangi EM, Nyambo B, Ndegwa PN, Subramanian S. "14.5 Population dynamics of Plutella xylostella (Lepidoptera: Plutellidae) and Its Parasitoids Along Altitudinal Gradients of the Eastern Afromontane." Symposium on Biological Control of Arthropods. 2017:231.
Mburu MM, Collins K Mweresa, Philemon Omusula, Alexandra Hiscox, Takken W, Wolfgang R Mukabana. "2-Butanone as a carbon dioxide mimic in attractant blends for the Afrotropical malaria mosquitoes Anopheles gambiae and Anopheles funestus." Malaria journal. 2017;16(1):351.
Ambale 1. CA, Sinei KA, Amugune BK, Oluka MN. "Accessibility of medicines used in the management of substance use disorders in selected hospitals in Nairobi." African Journal of Pharmacology and Therapeutics. 2017;6(2):102-108.
A. S. Azi, Riechi A. R., Khatete I. W. "Adequacy Assessment of Government’s Budgetary Allocations for the Provision of Lecture Halls in Nigeria’s Federal Universities." International Journal of Social Sciences and Information Technology. 2017;II(XI):1455-1467.abstract_5.doc
Wanjala, G., Akumu Maurice O. "Adminstrative Strategies Towards Disaster Awareness and Preparedness in Secondary Schools in Homa-Bay County, Kenya." International Journal of Development Research . 2017;7(10):16420-16423 .abstract3.pdf
Sherrif SS, Madadi V. "Adsorption of Lambda Cyhalothrin onto Athi River Sediments: Apparent Thermodynamic Properties." International Journal of Scientific Research in Science, Engineering and Technology. 2017;3(3):568-574.
Muinde VM, Onyari JM, Wamalwa B, Wabomba J, Nthumbi RM. "Adsorption of Malachite Green from Aqueous Solutions onto Rice Husks: Kinetic and Equilibrium Studies." Journal of Environmental Protection. 2017;8(03):215. AbstractWebsite

A study was done to evaluate the removal of a cationic dye from simulated waste water onto rice husks (RH). Spectroscopic methods such as FTIR and SEM/EDX were used for adsorbent characterization. Experimental dependency on solution pH, initial dye concentration, agitation speed, adsorbentparticle size, temperature of the solution and contact time was evaluated. The adsorption data was tested using both Langmuir and Freundlich isotherms. The data fitted well into Langmuir isotherm model with a monolayer adsorption capacity of 6.5 mg/g. Further, the separation factor (RL) value was less than unity indicating a favorable adsorption process. Adsorption kinetics was determined using pseudo-first-order, pseudo-second-order and intra-particle diffusion models. The results showed that the adsorption of malachite green onto rice husks followed pseudo-second-order model with a determination coefficient of 0.986. This work has revealed that rice husks have a great potential to sequester cationic dyes from aqueous solutions and therefore it can be utilized to clean contaminated effluents.

Muinde VM, Onyari JM, Wamalwa B, Wabomba J, Nthumbi RM. "Adsorption of malachite green from aqueous solutions onto rice husks: Kinetic and equilibrium studies." Journal of Environmental Protection. 2017;8(03):215. Abstract

A study was done to evaluate the removal of a cationic dye from simulated waste water onto rice husks (RH). Spectroscopic methods such as FTIR and SEM/EDX were used for adsorbent characterization. Experimental dependency on solution pH, initial dye concentration, agitation speed, adsorbentparticle size, temperature of the solution and contact time was evaluated. The adsorption data was tested using both Langmuir and Freundlich isotherms. The data fitted well into Langmuir isotherm model with a monolayer adsorption capacity of 6.5 mg/g. Further, the separation factor (RL) value was less than unity indicating a favorable adsorption process. Adsorption kinetics was determined using pseudo-first-order, pseudo-second-order and intra-particle diffusion models. The results showed that the adsorption of malachite green onto rice husks followed pseudo-second-order model with a determination coefficient of 0.986. This work has revealed that rice husks have a great potential to sequester cationic dyes from aqueous solutions and therefore it can be utilized to clean contaminated effluents.

Henry M. "Advances in Embryo Transfer Techniques." KVA Kisumu Branch Conference, Kisumu; 2017.
Okaru AO, Abuga KO, Kibwage IO, Hausler T, Luy B, Kuballa T, Rehm J, Lachenmeier DW. "Aflatoxin contamination in unrecorded beers from Kenya – A health risk beyond ethanol." Food Control. 2017;79:344-348. Abstract

Samples of unrecorded opaque beers (n=58; 40 based on maize, 5 on sorghum and 13 on other plants) and recorded wines (n=8) in Kenya were screened for aflatoxins using a rapid ELISA technique followed by confirmation using liquid chromatography-tandem mass spectrometry. Six of the maize beers were obtained from Kibera slums in Nairobi County. Aflatoxin contamination was detected in six unrecorded beers (10%), but in none of the recorded wines. Remarkably, three of the aflatoxin positive samples were from the Kibera slums.
The concentration of aflatoxins in the positive samples had a mean of 3.5 µg/L (range 1.8–6.8 µg/L), corresponding for an average consumption of 500 mL (1 standard drink) to a margin of exposure (MOE) of 36 (range: 15–58), which is considered as risk. On the other hand, the alcoholic strength of the aflatoxin positive samples had a mean of 4.3% vol (range 3.5-4.8%) corresponding to a MOE of 2.5 (range of 2.2-3.0) for the equivalent consumption volume. While aflatoxins pose a risk to the consumer, this risk is about 10 times lower than the risk of ethanol.
The Joint FAO/WHO Expert Committee on Food Additives sets no acceptable daily intake for aflatoxins since they are genotoxic carcinogens and instead recommends for the reduction of aflatoxin dietary exposure as an important public health goal, particularly in populations who consume high levels of any potentially aflatoxins contaminated food. Nevertheless, ethanol still posed a considerably higher risk in the unrecorded beers examined. However, consumers should be informed about aflatoxins, as these are an involuntary and unknown risk to them. In addition, producers should be educated about measures to reduce aflatoxins.

Okaru AO, Abuga KO, Kibwage IO, Hausler T, Luy B, Kuballa T, Rehm J, Lachenmeier DW. "Aflatoxin contamination in unrecorded beers from Kenya – A health risk beyond ethanol." Food Control. 2017;79(9):344-348.Website
Udomkun P, Wiredu AN, Mutegi C, Atehnkeng J, Nagle M, Nielsen F, Müller J, Vanlauwe B, Bandyopadhyay R. "Aflatoxin distribution in crop products from Burundi and Eastern Democratic Republic of Congo.". 2017:1.
Genga EK, Oyoo O, Espinoza LR, Adebajo A. "Africa Journal of Rheumatology: enhancing the visibility of rheumatology in Africa.". 2017. Abstractajr_enhancing_the_visibility_of_rheumatology_in_africa_2017-clinical_rheumatology.pdf

Africa Journal of Rheumatology: enhancing the visibility
of rheumatology in Africa
Eugene K. Genga1,2 & Omondi Oyoo1,2 & Luis R. Espinoza3 & Adewale Adebajo4
Received: 5 July 2017 /Accepted: 10 July 2017
# International League of Associations for Rheumatology (ILAR) 2017
Clinical Rheumatology welcomes the African Journal of
Rheumatology as an important development for the furtherance
of rheumatological scholarship and education on the
African continent and for rheumatology research in
Africans. It is hoped that this development will in turn raise
the profile of rheumatological conditions in Africa and among
Africans. In particular, it is hoped that this will lead to the
much needed collection of African musculoskeletal epidemiological
and health services data, assist in the training of
African rheumatologists, help to open up African rheumatology
to the global rheumatology community, and ultimately
improve the quality of care for myriads of Africans with rheumatic
The current population of Africa is 1,241,858,354
which is equivalent to 16.36% of the total world population
based on the latest United Nations estimates [1].
There are many challenges facing Africa including limited
financial resources, misuse of finances, malnutrition, poor
water, and sanitation among others. Despite these many
challenges faced in Africa, in recent times, the continent
has undergone rapid economic growth and development.
The available healthcare resources are overburdened by
the high burden of communicable diseases and the rising
prevalence of non-communicable diseases. Rheumatic
diseases are therefore not considered a high priority by
the various African governments. Part of the reason for
this is due to the limited epidemiological data on rheumatic
diseases and their burden in Africa. Scientific
journals play a central role in the dissemination of research
results which will ultimately impact on policy
change. Horton et al. [2] noted that researchers and policy
makers in developing countries believe that the main way
to solve problems of developing countries is by using
information from Western research rather than using local
data to solve regional problems. He, however, noted that
in Africa “there is already a well-developed local information
culture that needs support, not swamping,” noting,
moreover, the lack of African journals in MEDLINE [2].
Researchers in Africa and the developing world require
access not only as readers but also as authors: for them
to feel part of the global science community, they need
not only to obtain information but also to be able to contribute
to it and take part in the global discourse. The
continent’s resources are prioritized towards infectious
diseases like HIV and malaria over the now increasing
non-communicable diseases. Data on rheumatic diseases
in Africa has been limited partly due to lack of infrastructure
thus under diagnosis but also due to low scholarly
output. Thus, the Africa Journal of Rheumatology was
born. Since its inception 5 years ago, it has provided an
uninterrupted forum through which medical practitioners
and scientists from Africa and beyond can publish their
rheumatology research. It has become a rich source of
information about rheumatic disorders in the continent
and a timely addition to our worldwide rheumatology
community [3]. The journal has published various research
articles on diseases once thought to be rare in Africa. They
* Adewale Adebajo
1 Department of Clinical Medicine and Therapeutics, College of
Health Sciences, University of Nairobi/Kenyatta National Hospital,
Nairobi, Kenya
2 Nairobi Arthritis Clinic, Nairobi, Kenya
3 Louisiana State University School of Medicine, New Orleans, LA,
4 Faculty of Medicine, Dentistry and Health, University of Sheffield,
Sheffield, UK
Clin Rheumatol
DOI 10.1007/s10067-017-3761-z
range from rheumatoid arthritis, lupus, gout, myositis to rheumatology
in HIV. Research articles published in the journal
shows rheumatoid arthritis, juvenile idiopathic arthritis, systemic
lupus erythematosus, and antiphospholipid syndrome to
be increasing in frequency in the indigenous populations of
East, West, Central, and Southern Africa [4–7]. The HIV pandemic
has changed the epidemiological spectrum of diseases
in Africa. It has led to an increase in a variety of previously
rarely seen conditions like spondyloarthropathies, fibromyalgia,
pyomyositis, and scleroderma. Various scholars have
shared their experiences in the journal [8–12]. The journal
has also provided a forum through which scholars have been
able to share their experiences in management of the rheumatic
diseases with biologic therapy. The results have been similar
to data from around the world [13, 14]. Case reports of rare
diseases and review articles have not been left out and have
enriched the content of the journal bringing diversity in the
articles published.
The visibility of the journal is hampered by the low scholarly
output. This is in part due to severe limitations in the
overall economic development and especially in research infrastructure.
Researchers have limited access to funding for
research as most African countries have no national agencies
that are responsible for research. This is compounded by limitations
in scientific writing, designing, and conducting research
and in reporting the results. Partnership with international
journals like the African Journal Partnership Project is
welcome to bridge that gap by training African health researchers
to improve the quality and visibility of their research
and make the Africa journal of rheumatology a better resource
for local researchers and policy makers [15].
This journal has become a site for exchange of knowledge
of local rheumatic diseases, research, and debate and providing
a forum through which international research can be made
applicable to the African set-up. The Africa Journal of
Rheumatology encourages international agencies, which conduct
research in the region to support the journal through
submission of research and subscription to the publication. It
is our hope that this journal will provide a big step to bridge
the big gaps in rheumatology in Africa.
Compliance with ethical standards
Disclosures None.
1. Worldometers (2017) (
2. Horton R (2000a) Development aid: manna or myth? Lancet 356:
3. Espinoza LR (2014) Welcoming an African asset: African Journal
of Rheumatology. Afr J Rheumatol 2(2):47–48
4. Otieno FO, Moots RJ, Oyoo GO (2017) Rheumatoid arthritis in
Kenya. Afr J Rheumatol 5(1):1–2
5. Akintayo RO, Aworinde OO, Olawumi HO, Yusuf IA (2016)
Antiphospholipid syndrome in Africa: a review. Afr J Rheumatol
6. Genga EK, Otieno FO, Oyoo GO (2015) Clinical profiles of patients
SLE in Nairobi. Afr J Rheumatol 3(2):62–66
7. Adelowo F (2013) Systemic lupus erythematosus: not a rare disease
among black Africans. Afr J Rheumatol 1(2):46–47
8. Oyoo GO, Genga EK, Otieno FO, Omondi EA (2016) Clinical
patterns of juvenile idiopathic arthritis: a single tertiary centre experience
in Kenya Nairobi. Afr J Rheumatol 4(2):66–71
9. Venkat R, Jawad ASM, Chikanza IC (2014) Spontaneous resolution
of a case of anti-retroviral treatment-naïve HIV-associated
polymyositis. Afr J Rheumatol 2(2):78–84
10. Ilovi S, Oyoo G (2013) Characteristics of systemic sclerosis patients
in Nairobi, Kenya: a retrospective study. Afr J Rheumatol 1(1):8–12
11. Malombe NM, Oyoo GO, Maritim MC, Kwasa J (2013) Prevalence
of fibromyalgia in ambulatory HIV positive patients with musculoskeletal
pain at Comprehensive Care Clinic, Kenyatta National
Hospital. Afr J Rheumatol 1(2):70–75
12. Ouédraogo DD, Ouédraogo T, Kaboré F et al (2013) Prevalence of
HIV infection among the patients with an avascular necrosis of the
femoral head in Ouagadougou, Burkina Faso Ouédraogo. Afr J
Rheumatol 1(2):57–60
13. Oyoo GO, Otieno FO, Mbuthia B, Omondi EA, Genga EK (2015)
Experience with rituximab in patients with rheumatoid arthritis in
Nairobi, Kenya. Afr J Rheumatol 3(1):17–21
14. Elhabbash B, Tarsin R (2017) Certolizumab effect in a cohort of 60
Libyan patients with rheumatic diseases. Afr J Rheumatol 5(1):19–
15. Muula AS (2008) Medical journals and authorship in low-income
countries. Croat Med J 49:681–683

Gor SO. "The African Regional Integration Index: a Selective Audit." Trade and Development Review. 2017;9(1-2):86-98.
Wachege PN, Cherono F. "African Socio-religio Cultural Understanding of Family and Parenting: A Case of the Agikuyu, Kenya." The International Journal of Humanities and Social Studies. 2017;5(3):23-28.wachege_cherono_article2.pdf
Nyamai C, Daniel Ichang'i, Wamunyu AW, Feneyrol J, Giuliani G, et al. "Age and origin of the tsavorite and tanzanite mineralizing fluids in the Neoproterozoic Mozambique Metamorphic Belt." The Canadian Mineralogist. 2017;55(4):763-786. AbstractFull Text

The genetic model previously proposed for tsavorite- (and tanzanite-) bearing mineralization hosted in the Neoproterozoic Metamorphic Mozambique Belt (stretching from Kenya through Tanzania to Madagascar) is refined on the basis of new Sm-Nd age determinations and detailed Sr-O-S isotope and fluid-inclusion studies. The deposits are hosted within meta-sedimentary series composed of quartzites, graphitic gneisses, calc-silicate rocks intercalated with meta-evaporites, and marbles. Tsavorite occurs either in nodules (also called “boudins”) oriented parallel to the metamorphic foliation in all of the deposits in the metamorphic belt or in quartz veins and lenses located at the hinges of anticlinal folds (Lelatema fold belt and Ruangwa deposits, Tanzania). Gem tanzanite occurs in pockets and lenses in the Lelatema fold belt of northern Tanzania.

The Sm-Nd isotopic data for tsavorites and tanzanites hosted in quartz veins and lenses from Merelani demonstrate that they formed at 600 Ma, during the retrograde metamorphic episode associated with the East African Orogeny. The tsavorites hosted in nodules do not provide reliable ages: their sedimentary protoliths had heterogeneous compositions and their Sm-Nd system was not completely rehomogenized, even at the local scale, by the fluid-absent metamorphic recrystallization.

The initial 87Sr/86Sr isotopic ratios of calcite from marble and tanzanites from Merelani fit with the strontium isotopic composition of Neoproterozoic marine carbonates. Seawater sediment deposition in the Mozambique Ocean took place around 720 Ma.

The quartz-zoisite O-isotopic thermometer indicates a temperature of formation for zoisite between 385 and 448 °C.

The sulfur isotopic composition of pyrite (between –7.8 and –1.3‰ V-CDT) associated with tsavorite in the Lelatema fold belt deposits suggests the contribution of reduced marine sulfate. The sulfur in pyrite in the marbles was likely derived from bacterial sulfate reduction which produced H2S. Fluid inclusion data from tsavorite and tanzanite samples from the Merelani mine indicate the presence of a dominant H2S-S8±(CH4)±(N2)±(H2O)-bearing fluid. In the deposits in Kenya and Madagascar, the replacement of sulfate by tsavorite in the nodules and the boron isotopic composition of tourmaline associated with tsavorite are strong arguments in favor of the participation of evaporites in garnet formation.

Chimoita EL, Onyango CM, Kimenju JW, ph -Onyango JGP. "Agricultural Agents influence on the Uptake of Improved Sorghum Technologies." Journal of Agricultural Research. 2017;5(4):219-225.
Chimoita EL, Onyango CM, John W. Kimenju, Gweyi-Onyango JP. "Agricultural Extension Approaches Influencing Uptake of Improved Sorghum Technologies in Embu County, Kenya." Universal Journal of Agricultural Research . 2017;5(1):45-51.
Kibera AN, Kuria MW, Kokonya DA. "Alcohol Use Disorders among HIV and AIDS Patients at Kenyatta National Hospital (KNH) Comprehensive Care Centre, Nairobi, Kenya." International Journal of Research and Health Sciences. 2017;2(7):21-30.
Inyega HN, Inyega JO. All teachers teaching reading all children reading: a pedagogical shift in teacher education in Kenya. Nairobi: Jo-Vansallen Publishing Company ; 2017.
Mureithi AW, Onyari JM, Wanyonyi WC, Mulaa FJ. "Amino acid Composition of Gelatin Extracted from the Scales of Different Marine Fish Species in Kenya.". 2017. AbstractFull text link

Gelatin in this study was extracted by an enzymatic process from the scales of three marine fish species; Lutjanus
sebea (Red snapper), Lethrinus harak (Black spot emperor) and Scalus ghobban (Blue barred parrot fish).
Concentration of bacteria for mass production of enzyme was done in a fermentation medium using a bio reactor.
Scales were hydrolyzed at 500C and the pH maintained at 12. Complete hydrolysis took between 20 and 23 days for
all species. The yield for the dried gelatin was between 28.2% and 41.4% for the marine fish scales under study.
Fourier transform infrared spectra showed the presence of amide bands and two other additional absorption bands,
indicating the presence of amide bonds for all the three species. The amino acid composition analysis for the gelatin
of three species was then done showing the presence of 16 amino acids. Glycine was the most abundant for all the
three species with about 35% followed by Alanine both adding up to around 50% of the total amino acid
compositions. The amount of Proline was high for red snapper at over 14.2% compared to 11.1% and 11.6% for
blue barred parrot fish and black spot emperor respectively.

Mukaria SM, Thenya T, Raphael G Wahome, Karatu K. "Analysis and Perception of Health Impact of Motor Vehicle Emissions on Traffic Police in Nairobi, Kenya." Journal of Environment Pollution and Human Health. 2017;5(3):104-110.
Roberts LC, Otieno DJ, Nyikal RA. "An analysis of determinants of access to and use of credit by smallholder farmers in Suakoko district, Liberia." African Journal of Agricultural Research (AJAR). 2017;12(24)(ISSN – 1991-637x):2093-2100.
Madadi VO, Wandiga SO, Ndunda EN, Mavuti KM. "Analysis of Organochlorine Pesticides in Lake Naivasha Catchment." IJSRSET. 2017;3(5):139-149.
NDIRANGU MAINADAVID, CHIRA ROBERTMUTUGI, Wang’ondu V, Kairo JG. "Analysis of wave energy reduction and sediment stabilization by mangroves in Gazi Bay, Kenya." Bonorowo Wetlands. 2017;7(2):83-94.
NDIRANGU MAINADAVID, CHIRA ROBERTMUTUGI, Wang’ondu V, Kairo JG. "Analysis of wave energy reduction and sediment stabilization by mangroves in Gazi Bay, Kenya." Bonorowo Wetlands. 2017;7(2):83-94.
IRIBEMWANGI PI. "Analytical Issues in Standard Kiswahili Phonology." Reyono Journal of Interdisciplinary Studies. 2017;6(1):52-68.20180523_172417.jpg20180523_172417.jpg
Makokha E, WAKASIAKA S, Inyama H, Oyieke J. "Antenatal care and birth outcomes relatedto HIV status among pregnant women at Pumwani Maternity Hospital. ." Kenya Journal of Nursing & Midwifery . 2017;2(2).
Odwory M, Oyieke JBO, Machoki JM, Osoti A. "Antental care visits and pregnancy outcomes at a Kenyan rural District Hospita.". 2017.
Musi, C, MIRIKAU, N, D. "Antibacterial and antifungal activities of 10 Kenyan Plectranthus species in the Coleus clade." Journal of Pharmacy Research. 2017;11(8):1003-1014 . Abstractantibacterial_antifungal_plectranthus_2017.pdfWebsite

Background Information: Plectranthus L’Hér. is an economically important genus with horticultural, medicinal and food uses. Most Plectranthus species are used in traditional medicine and have attracted the interest of researchers who have studied them in attempt to explore the bioactivities of their phytoconstituents.
Materials and Methods: The current study investigated the antimicrobial activities of 10 Kenyan Plectranthus species through disc diffusion and broth dilution method.
Results:Results indicated that, dichloromethane/methanol (1:1) total leaf extracts from Plectranthus barbatus displayed the highest antimicrobial activity compared to the other nine Plectranthus species with minimum inhibitory concentration (MIC) values of 25, 40, 100, 50, and 100 mg/ml against methicillin resistant Staphylococcus aureus (MRSA), Bacillus cereus, Escherichia coli, Candida albicans, and Aspergillus niger, respectively. At a concentration of 200 mg/ml, the antibacterial activity of total leaf extracts of P. barbatus (MIC value = 25 mg/ml) and Plectranthus lanuginosus (MIC value = 40 mg/ml) againstMRSA was not significantly different from positive control drug; amoxicillin. Similarity, at a concentration of 200 mg/ml,total leaf extracts from Plectranthus ornatus (MIC value= 50 mg/ml) and P. barbatus (MIC value = 50 mg/ml) exhibited antifungal activity against C. albicans which was not significantly different from that of the positive control; ketoconazole.
Conclusion: The study reports for the first time, the antimicrobial activity of Plectranthus pseudomarrubioides, Plectranthus edulis, Plectranthus aegyptiacus, Plectranthus Otostegioides, and Plectranthus lanuginosus. The study has demonstrated broad bacteriostatic activity of P. barbatus and thus recommends further studies on this plant aimed at discovery of novel antimicrobial agents.
KEY WORDS: Antimicrobial activity, Bioguidance, Minimum inhibitory concentration, Plectranthus

Musila FM, Nguta JM, Lukhoba CW, Dossaji SF. "Antibacterial and antifungal activities of 10 Kenyan Plectranthus species in the Coleus clade." Journal of Pharmacy Research| Vol. 2017;11(8):1003.
Musila, F.M., Nguta, CM, Lukhoba CW, S.F. D. "Antibacterial and antifungal activities of 10 Kenyan Plectranthus species in the Coleus clade." Journal of Pharmacy Research . 2017;11(8):1003-1014.
Musila FM, Lukhoba CW, Dossaji SF. "Antibacterial and antifungal activities of 10 Kenyan Plectranthus species in the Coleus clade." Journal of Pharmacy Research. 2017;Vol. 11,(Issue 8):pp 1003-1014.
and Gakuubi MWAWJM 4. "Antifungal activity of essential oil of Eucalyptus camaldulensis Dehnh. against selected Fusarium spp.". 2017. Abstract

The objective of this study was to evaluate the antifungal activity of essential oil (EO) of
Eucalyptus camaldulensis Dehnh. against five Fusarium spp. commonly associated with
maize. The essential oil had been extracted by steam distillation in a modified Clevenger-
type apparatus from leaves of E. camaldulensis and their chemical composition
characterized by gas chromatography mass spectrometry. Poisoned food technique was
used to determine the percentage inhibition of mycelial growth, minimum inhibitory …

Kawaljit S, Okombo J, Brunschwig C, Ndubi F, Barnard L, Wilkson C, Njogu PM, Njoroge M, et al. "Antimalarial pyrido[1,2-a]benzimidazoles: Lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics and in vivo oral efficacy in a mouse model." J. Med. Chem. 2017;60(4):1432-1448.
Mubiu JK, Ndwigah SN, Abuga KO, Ongarora DSB. "Antimicrobial activity of extracts and phytosterols from the root bark of Lonchocarpus eriocalyx." East Cent. Afr. J. Pharm. Sci. . 2017;20:13-16. Abstract

The root bark of Lonchocarpus eriocalyx was dried, powdered and extracted using chloroform, methanol and hot water. The extracts exhibited antibacterial activity against Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus and antifungal activity against Saccharomyces cerevisiae. The decoction (100mg/ml) was more active than the chloroform and methanol extracts against the four microorganisms. Chromatographic fractionation of the chloroform extract using normal phase silica yielded the phytosterols lupeol and lupenone. At 100 mg/ml, the compounds were active against all the four microorganisms, with lupeol being more active than lupenone. This is the first report of the isolation of lupenone from Lonchocarpus eriocalyx.

Mubiu JK, Ndwigah SN, Abuga KO, Ongarora DSB. "Antimicrobial activity of extracts and phytosterols from the root bark of Lonchocarpus eriocalyx." East and Central African Journal of Pharmaceutical Sciences. . 2017;20:13-16.
Chalo DM, Lukhoba CW, Dossaji, S. F. "Antimicrobial activity, toxicity and phytochemical screening of selected medicinal plants of Losho, Narok County, Kenya. ." Journal of Natural Product Biochemistry. 2017;Vol 15((1)):pp. 29-43.
Waithaka PN, Mwaura FB, Wagacha JM, Gathuru EM, Githaiga BM. "Antimicrobial Properties of Actinomycetes Isolated from Menengai Crater in Kenya." CellBio. 2017;06(2):13.
Kama-Kama F, Omosa LK, Nganga J, Maina N, Osanjo G, Yaouba S, Ilias M, Midiwo J, Naessens J. "Antimycoplasmal Activities of Compounds from Solanum aculeastrum and Piliostigma thonningii against Strains from the Mycoplasma mycoides Cluster." Frontiers in Pharmacology. 2017;9:920.
Kama-Kama F, Omosa LK, Nganga J, Maina N, Osanjo G, Yaouba S, Ilias M, Midiwo J, Naessens J. "Antimycoplasmal Activities of Compounds from Solanum aculeastrum and Piliostigma thonningii against Strains from the Mycoplasma mycoides Cluster." Frontiers in pharmacology. 2017;8:920. Abstract

Infections caused by Mycoplasma species belonging to the ‘mycoides cluster’ negatively affect the agricultural sector through losses in livestock productivity. These Mycoplasma strains are resistant to many conventional antibiotics due to the total lack of cell wall. Therefore there is an urgent need to develop new antimicrobial agents from alternative sources such as medicinal plants to curb the resistance threat. Recent studies on extracts from Solanum aculeastrum and Piliostigma thonningii revealed interesting antimycoplasmal activities hence the motivation to investigate the antimycoplasmal activities of constituent compounds. The CH2Cl2/MeOH extracts from the berries of S. aculeastrum yielded a new β-sitosterol derivative (1) along with six known ones including; lupeol (2), two long-chain fatty alcohols namely undecyl alcohol (3) and lauryl alcohol (4); two long-chain fatty acids namely; myristic acid (5) and nervonic acid (6) as well as a glycosidic steroidal alkaloid; (25R)-3β-{O-α-L-rhamnopyranosyl-(1→2)-O-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranosyloxy-22α-N-spirosol-5-ene (7) from the MeOH extracts. A new furan diglycoside, (2,5-D-diglucopyranosyloxy-furan) (8) was also characterized from the CH2Cl2/MeOH extract of stem bark of P. thonningii. The structures of the compounds were determined on the basis of spectroscopic evidence and comparison with literature data. Compounds 1, 3, 4, 7 and 8 isolated in sufficient yields were tested against the growth of two Mycoplasma mycoides subsp. mycoides (Mmm), two M.mycoides. capri (Mmc) and one M. capricolum capricolum (Mcc) using broth dilution methods, while the minimum …

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