Publications

Found 47248 results

Sort by: Author Title Type [ Year  (Desc)]
1982
RAI MRVYASYASHWANT. ""Doctors and Standard of Medical Care", New Straits Times, Kuala Lumpur (November 16.". In: Nairobi Law Monthly 29, 31.; 1982. Abstract
n/a
DR. AKUNDA ELIJAHM. "E. M. W. Akunda, S. K. Imbamba and D. Kumar. Responses of coffee Arabia to pruning in Kenya.". In: Journal of science and technology (B) (1982) 3: 83 . Kisipan, M.L.; 1982. Abstract
n/a
MWIGA PROFMWABUGERMANO. "The Economics of Primary Health Care.". In: Proceedings Sixth College on Thin Film Technology, July 24th . University of Nairobi; 1982. Abstract
The role of pastoralist women in conflict resolution and management (study funded by SIDA though IMPACT)
O PROFBWIBONIMROD. "The effect of chronic childhood malnutrition on pubertal growth and development. Am J Clin Nutr . 1982 Sep; 36 ( 3 ): 527-36 . PMID: 7113957 [PubMed - indexed for MEDLINE] Kulin HE, Bwibo N, Mutie D, Santner SJ.". In: Am J Clin Nutr . 1982 Sep; 36 ( 3 ): 527-36. Anim. Hlth. Prod. Afr. 2008; 1982. Abstract

Pubertal growth and development were compared in 342 privileged, urban children and 347 impoverished rural adolescents from Kenya. Measurements of height, weight, upper arm circumference, and triceps skinfolds revealed marked differences between the two study groups just before the onset of sexual maturation. These differences were also found in the early stages of puberty but notable catch-up was evident throughout the later period of the maturational process. Early stages of sexual maturity were delayed by 3 yr in malnourished boys with a 2.1-yr lag in the age of onset of menarche in rural girls. Derived estimates of body fat as well as direct anthropometry revealed that the onset of puberty is not size related under the circumstances of chronic childhood malnutrition.

PMID: 7113957 [PubMed - indexed for MEDLINE]

IKIARA MRGERRISHONK. "The Effects of Increased Energy Costs on Balance of Payments and Real Incomes in Kenya.". In: ILO Proejct paper. Asian Economic and Social Society; 1982. Abstract
JASPA Working Paper, ILO, Addis Ababa
P. PROFMUREITHILEOPOLD. "Employment, Technology and Industrialization in Kenya: A Study in Development Strategy. Dissertation Abstracts International Seriess A Vol. 35, No. 1.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1982. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
PROF. KHAMALA CANUTEPM. "Establishment of Pine Woolly Aphid Pineus pini (L) (Homoptera: Adelgidae) on some host trees.". In: Kenya J. Sci. Tech.3:61-68. Opuscula Mathematica,; 1982. Abstract
n/a
A. PROFKARANIFLORIDA. ""Evaluating the Process and Products of a Programme".". In: Presented at the UNICEF second Sub-Regional workshop: Nazareth, Ethiopia, November 1982. Journal of BiochemiPhysics; 1982. Abstract
   
A. PROFKARANIFLORIDA. ""Evaluating the Process and Products of a Programme".". In: Presented at the UNICEF second Sub-Regional workshop: Nazareth, Ethiopia, November 1982. Journal of BiochemiPhysics; 1982. Abstract

 

 

A. PROFKARANIFLORIDA. ""Evaluation Models".". In: Presented at the Institute of Adult Studies, University of Nairobi seminar, 1982. Journal of BiochemiPhysics; 1982. Abstract
   
A. PROFKARANIFLORIDA. ""Evaluation Models".". In: Presented at the Institute of Adult Studies, University of Nairobi seminar, 1982. Journal of BiochemiPhysics; 1982. Abstract

 

 

SAMUEL PROFKIBICHO. ""Evolution and the christian teaching on creation," Salam Journal for Religious Education.". In: Proceedings of 3rd Int. Conf. On bearing capacity of roads and airfields PP 743-756, Trondeihm, Norway. Longhorn; 1982. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
K DRNDERUFM. "Exposure of calves to taeniid eggs of wild carnivore origin. Bull. Animal Prod. In Africa 30(1) 1982.". In: M.Sc. Thesis University of Nairobi. East African Journal of Development Studies; 1982. Abstract
A double antibody enzyme linked immunosorbent assay for identification of thermostable muscle antigens of autoclaved meat samples is described. The assay differentiates heterologous thermostable muscle antigens from homologous at P 0.001. In model meat mixtures, the assay detects adulterants at the level of 1% at p0.001 even in phylogenetically related species such as buffalo and cattle.
ISAAC PROFJUMBA, OYOO PROFWANDIGASHEM. "Factors affecting the simultaneous determination of cooper, lead, cadmium and zinc concentrations in human head hair using different pulse anodic stripping voltametry method.". In: Kenya J. Sci. Technol. (A) 3, 9-25. Academic Press Elsevier. Int.; 1982. Abstract
n/a
NJUGUNA PROFNGETHE. "Final Evaluation of Foot and Mouth Disease in Kenya. On behalf of Ministry of Livestock Development, Nairobi, 1982. IDS Consultancy Report No. 9 1982.". In: In Search of NGOS In Eastern and Southern Africa. IDS Occasional Paper No. 58:.; 1982. Abstract
n/a
MUCHAI PROFKAGIKOM, MWANGI PROFGATHUMAJ. "Gathuma, J.M., Nyaga, P.N., Omuse, J.K., Nderu, F. M. K. and Kaminjolo, J.S. (1982). Exposure of calves to taeniid eggs of wild carnivore origin. Bull. Anim. Hlth. Prod. Afr. 30 (1), 55 .". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
MUCHAI PROFKAGIKOM, MWANGI PROFGATHUMAJ. "Gathuma, J.M., Nyaga, P.N., Omuse, J.K., Nderu, F. M. K. and Kaminjolo, J.S. (1982). Exposure of calves to taeniid eggs of wild carnivore origin. Bull. Anim. Hlth. Prod. Afr. 30 (1), 55 .". In: journal. au-ibar; 1982. Abstract
Antisera to thermostable muscle antigens from 13 wild animals: Buffalo, Waterbuck, Bushbuck, Eland, Oryx, Kongoni, Bushpig, Warthog, Topi, Thomson’s gazelle, Grant’s gazelle, Sheep, Pig, Horse, Camel & Dog, were raised in rabbits and/or goats. Absorptions of the antisera with copolymerized pooled serum from the 20 species and the thermostable muscle antigens rendered most of the antisera mmonospecific. It was possible to identify the species of origin of saline extracts of both cooked and fresh meat samples in immunodiffusion tests. The method is promising for use in identification of the species origin of fresh and cooked animal meats.
O PROFBARONGOJUSTUS. "Geoelectric structure below Eburru geothermal field, Rift Valley, Kenya,.". In: Proceedings of the regional seminar on geothermal energy in Eastern and southern Africa, 15-21 June, 1982, Nairobi, Kenya. Canadian Center of Science and Education; 1982. Abstract
Barongo, J.O.,1982. Proceedings of the regional seminar on geothermal energy in Eastern and southern Africa, 15-21 June, 1982, Nairobi, Kenya.
O PROFNYAMBOKISAAC. "Geological excursion guide to the Kenya Rift Valley (Nairobi-Kijabe- Naivasha-Gilgil).". In: 6th Conference of African Geology, Nairobi. 15p. Wiley Interscience; 1982. Abstract
Nyambok, I.O.
K PROFMAITAICHARLES, N PROFGUANTAIA. "Guantai AN, Maitai CK.Relative distribution of cathinone and D-norpseudoephedrine in Catha edulis (Miraa) growing in Kenya.East Afr Med J. 1982 Jun;59(6):394-8.". In: East Afr Med J. 1982 Jun;59(6):394-8. A. N. GUANTAI, J. W. MWANG1, G1CHURU MURIUKI and K. A. M. KURIA; 1982. Abstract
Cathinone, a potent psychostimulant isolated from young shoots of Catha edulis was given to four human volunteers. Examination of urine collected from the volunteers at predetermined intervals showed the presence of unchanged cathinone, d-norpseudoephedrine, and two unidentified basic substances. The observed biotransformation of cathinone to the less potent psychostimulant, d-norpseudoephedrine involves reduction of a ketone group to alcohol, a common metabolic pathway in humans.
JAMEELA PROFHASSANALI. "Hassanali J, Odhiambo JW. Estimation of calendar age from eruption times of permanent teeth in Kenyan Africans and Asians. Ann Hum Biol. 1982 Mar-Apr;9(2):175-7.". In: American Journal of Physical Anthropology : 59: 317-319. Dar-es-salaam University Press (DUP) in 1996.; 1982. Abstract
Eruption data for permanent teeth, obtained from a previous cross-sectional study of 2847 African and Asian school children aged 4-14 years in Nairobi, Kenya, were used to calculate the median age and the 10th-90th percentile range of age, for a given number of teeth present. For a limited period (5-13 years) up to the time of eruption of second molars, the total number of permanent teeth erupted can be used to estimate the age of a child, with an error which increases with the number of teeth present. The range of this error is about 18-30% of the median age for African males, 21-29% for African females, 15-33% for Asian males and 18-33% for Asian females, with a 1 in 5 chance that the error may exceed these limits.
JAMEELA PROFHASSANALI. "Hassanali J.Incidence of cusp of Carabelli in Kenyan Africans and Asians. American Journal of Physical Anthropology : 59: 317-319(1982).". In: American Journal of Physical Anthropology : 59: 317-319. Dar-es-salaam University Press (DUP) in 1996.; 1982. Abstract

Examination for incidence of Carabelli's trait was done on 1267 Africans and 781 Asian school children, 298 dental plaster casts and 248 skulls of Africans. The African sample is composed of 80% Bantu, 20% Nilote, and Nilo-Hamitic people. When observed intraorally, the trait is present in 31-35% of Africans and 26-27% of Asians. In the dental casts and skull sample of Africans, the trait is present as pit in 23-28%, groove in 20%, and as tubercle and cusp in 22%. The total trait frequency in Africans is 68%.

MWIGA PROFMWABUGERMANO. "Health Care Decision.". In: Proceedings Sixth College on Thin Film Technology, July 24th . University of Nairobi; 1982. Abstract
The role of pastoralist women in conflict resolution and management (study funded by SIDA though IMPACT)
S. PROFMBINDYOBENJAMIN. "Heda, P.M., Jeshirani, M.K., Mbindyo, B.S.Tension-Band wiring of the olecranon fractures Proc. Ass. of Surgeons of E.A. pp 83-86 vol 5, 1982.". In: Ass. of Surgeons of E.A. pp 83-86 vol 5, 1982. University of Nairobi.; 1982. Abstract
Kenya is a country of marked environmental and ethnic diversity. A study of osteogenic sarcoma occurring in Kenya from 1968 to 1978 revealed 251 cases, representing between 89% and 100% of the predicted number. Variations in age, sex and anatomical location were within classical limits. However, the incidence of osteogenic sarcoma amongst the Central Bantu was significantly higher than predicted (P less than 0.0001), whilst the incidence among the Western Bantu was significantly lower (P less than 0.002), despite their similar ethnic origins. Two geographically dissimilar areas likewise exhibited significant differences in incidence. The Eastern province showed a higher incidence (P less than 0.02), whereas the Nyanza Province (P less than 0.001) and the adjacent Western Province (P less than 0.005) showed a lower than predicted incidence. These observations suggest that in Kenya a geomedical variable affects the incidence of osteogenic sarcoma and that genetic variation has no effect on incidence.
G PROFKARANJAJOSEPH. "Hormonal patterns during the menstrual cycles in healthy black Kenyan women.J Obstet Gynaecol East Cent Africa. 1982 Dec;1(4):140-4. Links.". In: J Obstet Gynaecol East Cent Africa. 1982 Dec;1(4):140-4. Links. Korean Society of Crop Science and Springer; 1982. Abstract
PIP: 17 regularly mentruating young black Kenyan women were studied during a mentrual cylcle for their reproductive hormonal patterns. The serum concentrations of Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Prolactin (PRL) were determined by World Health Organization Matched Reagent Programme Radioimmunoassay (WHO-MR-RIA). A biphasic basal body temperature (BBT) record was also noted. The hormonal patterns showed a mid-cycle LH surge and rise in plasma progesterone beginning with the LH peak and lasting a maximum of 6-8 days after the LH peak. Cycle lengths ranged from 25-32 days with a mean of 28 plus or minus 2 days. The follicular phase ranged from 10-17 days, and the luteal phase lasted from 13-15 days. When the mean LH and FSH concentrations and the mean BBT curve were synchronized on the day of the mid-cycle LH peak, the temperature elevation occured about 48 days after the LH peak. Along with the LH, the FSH showed a mid-cycle peak. The results of this study are consistent with those already documented for Caucasian, Asian and African females
P. PROFMUREITHILEOPOLD. "Investment Linkages of Rural Access roads in Kenya (Kenya Ministry of Transport and Communications November with B.P Finucane.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1982. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
JOAB PROFBWAYOJOB. "Isopycnic Isolation of African Trypanosomes on Percoll gradients formed in situ. Grab DJ. Bwayo JJ. (1982). Acta Topics, 39: 363?366.". In: Acta Topics, 39: 363?366. Asian Economic and Social Society; 1982. Abstract
The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. This cross-sectional study was conducted to measure the association between circumcision status and infection with HIV-1 among men with genital ulcer disease. Eight hundred and ten men participated in the study, of whom 190 (23%) were HIV-1-positive. A logistic regression model adjusted for behavioral and historical showed that HIV-1 positivity was independently associated with being uncircumcised (adjusted odds ratio [OR], 4.8; 95% confidence interval [CI], 3.3-7.2) and with a history of urethral discharge (adjusted OR, 2.0; 95% CI, 1.4-2.8). This association could not be explained by measures of sexual exposure to HIV-1 among this population. Male circumcision should be considered as an intervention strategy for AIDS control.
W PROFMWANGIJULIUS. "J.W. Mwangi, C.K. Maitai, and Talalaj (1982). Essential oil content of Eucalyptus citriodora (Hooker) growing in Kenya. Kenya J. Sci. Tech. 3: 55-56.". In: Kenya J. Sci. Tech. 3: 55-56. The Kenya Medical Association; 1982. Abstract
The effect of acqueous extract of the tuber of Adenia globosa on the isolated preparation of the rat uterus was determined. The crude drug caused a dose-dependent contraction of the tissue preparation. This action was enhanced by a small dose of oxytocin. The results are discussed in relation to the traditional uses of this plant.
S. PROFMBINDYOBENJAMIN. "Jeshirani, M.K., Bencivenga, A., Mbindyo, B.S., Heda, P.K., Gakuu, L.N. The management of post-traumatic limb length discrepancies Proc. Ass. of Surgeons of E.A. pp 181-186 vol 5 1982.". In: Ass. of Surgeons of E.A. pp 181-186 vol 5 1982. University of Nairobi.; 1982. Abstract
Kenya is a country of marked environmental and ethnic diversity. A study of osteogenic sarcoma occurring in Kenya from 1968 to 1978 revealed 251 cases, representing between 89% and 100% of the predicted number. Variations in age, sex and anatomical location were within classical limits. However, the incidence of osteogenic sarcoma amongst the Central Bantu was significantly higher than predicted (P less than 0.0001), whilst the incidence among the Western Bantu was significantly lower (P less than 0.002), despite their similar ethnic origins. Two geographically dissimilar areas likewise exhibited significant differences in incidence. The Eastern province showed a higher incidence (P less than 0.02), whereas the Nyanza Province (P less than 0.001) and the adjacent Western Province (P less than 0.005) showed a lower than predicted incidence. These observations suggest that in Kenya a geomedical variable affects the incidence of osteogenic sarcoma and that genetic variation has no effect on incidence.
S. PROFMBINDYOBENJAMIN. "Jeshirani, M.K., Bencivenga, A., Mbindyo, B.S., Heda, P.M., Gakuu, L.N.Non-union of Humerus: The consequences of unstable intramedullary nailingProc. Ass. of Surgeons of E.A. pp 171-175 vol. 6 1982.". In: Ass. of Surgeons of E.A. pp 171-175 vol. 6 1982. University of Nairobi.; 1982. Abstract
Kenya is a country of marked environmental and ethnic diversity. A study of osteogenic sarcoma occurring in Kenya from 1968 to 1978 revealed 251 cases, representing between 89% and 100% of the predicted number. Variations in age, sex and anatomical location were within classical limits. However, the incidence of osteogenic sarcoma amongst the Central Bantu was significantly higher than predicted (P less than 0.0001), whilst the incidence among the Western Bantu was significantly lower (P less than 0.002), despite their similar ethnic origins. Two geographically dissimilar areas likewise exhibited significant differences in incidence. The Eastern province showed a higher incidence (P less than 0.02), whereas the Nyanza Province (P less than 0.001) and the adjacent Western Province (P less than 0.005) showed a lower than predicted incidence. These observations suggest that in Kenya a geomedical variable affects the incidence of osteogenic sarcoma and that genetic variation has no effect on incidence.
KANYUA PROFMUGAMBIJESSENDWIGA. "Jesse Mugambi, J. Mutiso-Mbinda and J. Vollbrecht, Ecumenical Initiatives in Eastern Africa, Nairobi: AACC/AMECEA, 188 pp.".; 1982. Abstract

Introduction to Philosophy of Religion, University of Nairobi, 1988

MUCHAI PROFKAGIKOM. "Kagiko, M.M. Biological Weapons .". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
MUCHAI PROFKAGIKOM. "Kagiko, M.M. Limitations of Biological control of Arthropods. Kenya Farmer, June 1982, pp. 41.". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
MUCHAI PROFKAGIKOM. "Kagiko, M.M. Staphylococcal Food Intoxication. Kenya Farmer, August 1982, pp. 17.". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
MUCHAI PROFKAGIKOM. "Kagiko, M.M. Waging Biological Warfare Against Pests, Kenya Farmer, April 1982, pp.21.". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
OLE PROFMALOIYGEOFFREYM. "KAMAU, J.M.Z. and MALOIY, G.M.O.(1982) Heat balance of the dik-dik in the field and laboratory. Journal of Physiology London 322, 60P.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
OLE PROFMALOIYGEOFFREYM. "KAMAU, J.M.Z. and MALOIY, G.M.O.(1982) The relationship between rate of oxygen consumption, heart rate and thermal conductance of the dik-dik antelope (Rhynchotragus kirkii) at various ambient temperatures. Comparative Biochemistry and Physiology 73A, 21-.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
WILLIAM PROFMUNYUAKIMANI. "Kanyari, P.W.N., Allonby, E.W., Wilson, A.J. and Munyua, W.K.(1982): Trypanotolerance and economics among East African goats compared to their crosses with two exotic goat breeds. In: Karbe, E. and Freitas, E.K. (eds) 1982 pp. 93-99.". In: Proc. 8th Inter. Congress of Parasitol. (I.C.O.P.A.) October 10-14, Izmir-Turkey. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} The research sought to find out the extent to which mobile phone users were aware about safe disposal of mobile phones. In addition the research went ahead to establish the avenues available to mobile phone manufacturers and users in order to enhance safe mobile disposal through a survey.  The research revealed that there was the need for the mobile manufacturers to manufacture handsets from recyclable materials. The manufacturers should also avail information on handset disposal at the point of sale and do a follow-up using the available media. The mobile services providers can also play an important role on mobile phone disposal by availing the information on the face of the scratch cards. In addition they can notify the subscribers on the available disposal channels through text messages. The government through the designated agencies such as the Communications Commission of Kenya (CCK) and National Environmental Management Authority (NEMA) needs to be more assertive in mobile phone disposal measures. Key words: Recycle, Disposal; Mobile Phone; handsets; Environment; Design; Kenya
R PROFMUTIGAERASTUS. "Kanyongo-Male, H., Karue, C.N. and Mutiga, E.R. 1982. The effect of preconception supplementation on the productivity of dairy heifers grazed on medium quality pasture under East African conditions. Bull. Anima. Hlth. Prod. 30:65-72.". In: Disc and Innov. Acd. Sci. Publ. Vol.1 No.4, 39-43 (1989). Erick Onyango Odada; 1982. Abstract
Data relating to reproductive parameters of German shepherd bitches were collected from registered German shepherd dog (GSD) breeders with information kept over a 15-year period (1982-1997). The information obtained was verified using the East African Kennel Club records. A total of 594 bitches from 280 breeders were recorded. From these, 798 heats were observed, 594 of which were used for breeding, resulting in 3592 puppies. The mean age at puberty was 519.0 +/- 41 days. Heats occurred throughout the year, although significantly (P < 0.05) higher and lower incidences were observed in October and April respectively Pregnancy significantly (P < 0.01) increased interoestrous interval, which was 247.8 +/- 99.6 and 183 +/- 52 days among bred/pregnant and non-bred bitches respectively. Most bitches in oestrus (73.7%) were bred, and breeding was carried out throughout the year, with a distribution closely related to that of heat incidence. Subsequently, whelping occurred throughout the year, and 95.5% of the bitches that were mated whelped. A mean gestation period of 60.6 +/- 5.1 days was observed. The mean litter size was 6.4 +/- 0.4 puppies, and did not differ significantly between months. The preweaning losses were low, with 2.3% stillbirths, 0.9% culls and 11.4% mortalities.
S DRKARANJAHDOMINIC. "Karanja D.S .". In: The Limnology, Climatology and Palaeoclimatology of the East African Lakes pp. 413-431, Gordon and Breach Publishers, Amsterdam. June 1996 b) Books Reference Date. Earthscan, London. 978-1-84407-469-3 (*); 1982. Abstract
n/a
S PROFKIGONDUCHRISTINE. "Karanja J.G., Gwayi-Chore M.O., Sekadde-Kigondu C.B.,Lequin R.M., Mati J.K.G.J. Obstet. Gynaecol. E. Central Afr. 1:140, 1982 Hormonal patterns during the menstrual cycle of healthy black Kenyan women.". In: Obstet. Gynaecol. E. Central Afr. 1:140, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Karanja J.K., Gwayi-Chore M.D., Sekadde-Kigondu C.B., et al J. Obstet. Gynaecol. E. Central Afr. 108, 1982. Value of FSH, LH and PRL assays in diagnosis of amenorrhoea.". In: et al J. Obstet. Gynaecol. E. Central Afr. 108, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Karanja JG, Gwanyi-chore MO, Sekadde-kigondu CB, Lequin RM, Mati JK. Hormonal patterns during the menstrual cycles in healthy black Kenyan women. J Obstet Gynaecol East Cent Africa. 1982 Dec;1(4):140-4.". In: J. Obs/Gyn. East Central Africa 1:126(1982). uon press; 1982. Abstract
PIP: 17 regularly mentruating young black Kenyan women were studied during a mentrual cylcle for their reproductive hormonal patterns. The serum concentrations of Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Prolactin (PRL) were determined by World Health Organization Matched Reagent Programme Radioimmunoassay (WHO-MR-RIA). A biphasic basal body temperature (BBT) record was also noted. The hormonal patterns showed a mid-cycle LH surge and rise in plasma progesterone beginning with the LH peak and lasting a maximum of 6-8 days after the LH peak. Cycle lengths ranged from 25-32 days with a mean of 28 plus or minus 2 days. The follicular phase ranged from 10-17 days, and the luteal phase lasted from 13-15 days. When the mean LH and FSH concentrations and the mean BBT curve were synchronized on the day of the mid-cycle LH peak, the temperature elevation occured about 48 days after the LH peak. Along with the LH, the FSH showed a mid-cycle peak. The results of this study
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG, GWAYI-CHORE MO, SEKADDE-KIGONDU CB, LEQUIN RM and MATI JKG: Hormonal patterns during the menstrual cycle in Healthy Black Kenyan women. J.Obstet.Gynae. East Centr. Afr. 1: 140, 1982.". In: J.Obstet.Gynae. East Centr. Afr. 1: 140, 1982. Korean Society of Crop Science and Springer; 1982. Abstract
This was a cross sectional descriptive study to discuss the median age of menopause in a rural area of Western Kenya. The broad objective of the study was to describe the demographic and biophysical characteristics of the study population and determine the age of menopause. A review of the current and medieval records shows average age of menopause has remained relatively constant at 50 years in contrast to the receeding age of menarche. A total of 1078 women aged between 40-60 years were interviewed. The majority (98.8%) were from one ethnic group, the Luhya. Of the 1078 women, 880 (81.4%) were married and 198 (18.6%) were single. The average number of children per woman was 7.74. Most of the women (75.1%) had attained primary school education. Their husbands were unskilled workers in 30.1% of the cases. The mean weight and height of the women was 60.74 kg and 161.1 cm respectively. Using methods of probit analysis, the median and modal age of menopause was found to be 48.28 years in this group of western Kenya women. If generalised for the whole country, these results suggest that an average Kenyan woman lives for over ten years beyond menopause. It is recommended that more attention should be given to the special health problems of postmenopausal population. PIP: This study describes the demographic and biophysical characteristics of rural menopausal women in Western Kenya. Menopause occurs as the gradual unresponsiveness of the human ovary to gonadotropins, premature ovarian failure at under 40 years, and menopause following surgical procedures of the uterus and ovaries. A 3-phase process starts with low serum estradiol and progesterone, followed by a rise in follicle stimulating hormone, and a rise in luteinizing hormone. Clinical symptoms include vasomotor ones, genitourinary ones, osteoporosis and increased incidence of bone fractures, increased incidence of thromboembolic and ischemic heart disease, and psychological symptoms of anxiety, depression, and memory loss. The age of menopause varies with socioeconomic conditions, race, parity, height, weight, skinfold thickness, lifestyle, and education. Data were obtained for this study from a sample of 1078 women from 7 sublocations in Vihiga division, Kenya. Women were aged 40-60 years. The most populous ethnic group was the Luhya. 81.6% were married, 15.6% were widowed, and 0.7% were divorced. 4 women had never been married. 75.1% had a primary school education; 18.6% had not received any formal education. 30.1% had husbands who were unskilled workers, 28.8% had husbands who were farmers, and 20.6% had husbands who were skilled workers. 1.3% had no children, and 1 woman had 17 children. The average number of children was 7.74. 9 of the nulliparous women were menopausal. The mean height was 161.1 cm. The median age at menopause was 48.28 years. Almost all women were menopausal by 55 years. The total fertility period averaged 35 years. Female life expectancy was 59 years
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG, GWAYI-CHORE MO, SEKADDE-KIGONDU CB, LEQUIN RM and MATI JKG: Hormonal patterns during the menstrual cycle in Healthy Black Kenyan women. J.Obstet.Gynae. East Centr. Afr. 1: 140, 1982.". In: J.Obstet.Gynae. East Centr. Afr. 1: 140, 1982. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG, MATI JKG, SEKADDE-KIGONDU CB: The value of FSH LH and prolactin assays in aetiological diagnosis of ammenorrhea. J.Obstet.Gynae. East Centr. Afr. 1:108, 1982.". In: J.Obstet.Gynae. East Centr. Afr. 1:108, 1982. Korean Society of Crop Science and Springer; 1982. Abstract
This was a cross sectional descriptive study to discuss the median age of menopause in a rural area of Western Kenya. The broad objective of the study was to describe the demographic and biophysical characteristics of the study population and determine the age of menopause. A review of the current and medieval records shows average age of menopause has remained relatively constant at 50 years in contrast to the receeding age of menarche. A total of 1078 women aged between 40-60 years were interviewed. The majority (98.8%) were from one ethnic group, the Luhya. Of the 1078 women, 880 (81.4%) were married and 198 (18.6%) were single. The average number of children per woman was 7.74. Most of the women (75.1%) had attained primary school education. Their husbands were unskilled workers in 30.1% of the cases. The mean weight and height of the women was 60.74 kg and 161.1 cm respectively. Using methods of probit analysis, the median and modal age of menopause was found to be 48.28 years in this group of western Kenya women. If generalised for the whole country, these results suggest that an average Kenyan woman lives for over ten years beyond menopause. It is recommended that more attention should be given to the special health problems of postmenopausal population. PIP: This study describes the demographic and biophysical characteristics of rural menopausal women in Western Kenya. Menopause occurs as the gradual unresponsiveness of the human ovary to gonadotropins, premature ovarian failure at under 40 years, and menopause following surgical procedures of the uterus and ovaries. A 3-phase process starts with low serum estradiol and progesterone, followed by a rise in follicle stimulating hormone, and a rise in luteinizing hormone. Clinical symptoms include vasomotor ones, genitourinary ones, osteoporosis and increased incidence of bone fractures, increased incidence of thromboembolic and ischemic heart disease, and psychological symptoms of anxiety, depression, and memory loss. The age of menopause varies with socioeconomic conditions, race, parity, height, weight, skinfold thickness, lifestyle, and education. Data were obtained for this study from a sample of 1078 women from 7 sublocations in Vihiga division, Kenya. Women were aged 40-60 years. The most populous ethnic group was the Luhya. 81.6% were married, 15.6% were widowed, and 0.7% were divorced. 4 women had never been married. 75.1% had a primary school education; 18.6% had not received any formal education. 30.1% had husbands who were unskilled workers, 28.8% had husbands who were farmers, and 20.6% had husbands who were skilled workers. 1.3% had no children, and 1 woman had 17 children. The average number of children was 7.74. 9 of the nulliparous women were menopausal. The mean height was 161.1 cm. The median age at menopause was 48.28 years. Almost all women were menopausal by 55 years. The total fertility period averaged 35 years. Female life expectancy was 59 years
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG, MATI JKG, SEKADDE-KIGONDU CB: The value of FSH LH and prolactin assays in aetiological diagnosis of ammenorrhea. J.Obstet.Gynae. East Centr. Afr. 1:108, 1982.". In: J.Obstet.Gynae. East Centr. Afr. 1:108, 1982. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG, SEKADDE-KIGONDU CB, MATI JKG, LEQUIN RM: Pulsitile release and diurnal rhythm of gonadotropins and prolactin in young healthy Kenyan men. J.Obstet.Gynae. East Centr. Afr.1: 77, 1982.". In: J.Obstet.Gynae. East Centr. Afr.1: 77, 1982. Korean Society of Crop Science and Springer; 1982. Abstract
This was a cross sectional descriptive study to discuss the median age of menopause in a rural area of Western Kenya. The broad objective of the study was to describe the demographic and biophysical characteristics of the study population and determine the age of menopause. A review of the current and medieval records shows average age of menopause has remained relatively constant at 50 years in contrast to the receeding age of menarche. A total of 1078 women aged between 40-60 years were interviewed. The majority (98.8%) were from one ethnic group, the Luhya. Of the 1078 women, 880 (81.4%) were married and 198 (18.6%) were single. The average number of children per woman was 7.74. Most of the women (75.1%) had attained primary school education. Their husbands were unskilled workers in 30.1% of the cases. The mean weight and height of the women was 60.74 kg and 161.1 cm respectively. Using methods of probit analysis, the median and modal age of menopause was found to be 48.28 years in this group of western Kenya women. If generalised for the whole country, these results suggest that an average Kenyan woman lives for over ten years beyond menopause. It is recommended that more attention should be given to the special health problems of postmenopausal population. PIP: This study describes the demographic and biophysical characteristics of rural menopausal women in Western Kenya. Menopause occurs as the gradual unresponsiveness of the human ovary to gonadotropins, premature ovarian failure at under 40 years, and menopause following surgical procedures of the uterus and ovaries. A 3-phase process starts with low serum estradiol and progesterone, followed by a rise in follicle stimulating hormone, and a rise in luteinizing hormone. Clinical symptoms include vasomotor ones, genitourinary ones, osteoporosis and increased incidence of bone fractures, increased incidence of thromboembolic and ischemic heart disease, and psychological symptoms of anxiety, depression, and memory loss. The age of menopause varies with socioeconomic conditions, race, parity, height, weight, skinfold thickness, lifestyle, and education. Data were obtained for this study from a sample of 1078 women from 7 sublocations in Vihiga division, Kenya. Women were aged 40-60 years. The most populous ethnic group was the Luhya. 81.6% were married, 15.6% were widowed, and 0.7% were divorced. 4 women had never been married. 75.1% had a primary school education; 18.6% had not received any formal education. 30.1% had husbands who were unskilled workers, 28.8% had husbands who were farmers, and 20.6% had husbands who were skilled workers. 1.3% had no children, and 1 woman had 17 children. The average number of children was 7.74. 9 of the nulliparous women were menopausal. The mean height was 161.1 cm. The median age at menopause was 48.28 years. Almost all women were menopausal by 55 years. The total fertility period averaged 35 years. Female life expectancy was 59 years
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG, SEKADDE-KIGONDU CB, MATI JKG, LEQUIN RM: Pulsitile release and diurnal rhythm of gonadotropins and prolactin in young healthy Kenyan men. J.Obstet.Gynae. East Centr. Afr.1: 77, 1982.". In: J.Obstet.Gynae. East Centr. Afr.1: 77, 1982. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG: Review of Caesarean Section deliveries at Kenyatta National Hospital 1980. M.Med Dissertation, University of Nairobi, 1982.". In: M.Med Dissertation, University of Nairobi, 1982. Korean Society of Crop Science and Springer; 1982. Abstract
This was a cross sectional descriptive study to discuss the median age of menopause in a rural area of Western Kenya. The broad objective of the study was to describe the demographic and biophysical characteristics of the study population and determine the age of menopause. A review of the current and medieval records shows average age of menopause has remained relatively constant at 50 years in contrast to the receeding age of menarche. A total of 1078 women aged between 40-60 years were interviewed. The majority (98.8%) were from one ethnic group, the Luhya. Of the 1078 women, 880 (81.4%) were married and 198 (18.6%) were single. The average number of children per woman was 7.74. Most of the women (75.1%) had attained primary school education. Their husbands were unskilled workers in 30.1% of the cases. The mean weight and height of the women was 60.74 kg and 161.1 cm respectively. Using methods of probit analysis, the median and modal age of menopause was found to be 48.28 years in this group of western Kenya women. If generalised for the whole country, these results suggest that an average Kenyan woman lives for over ten years beyond menopause. It is recommended that more attention should be given to the special health problems of postmenopausal population. PIP: This study describes the demographic and biophysical characteristics of rural menopausal women in Western Kenya. Menopause occurs as the gradual unresponsiveness of the human ovary to gonadotropins, premature ovarian failure at under 40 years, and menopause following surgical procedures of the uterus and ovaries. A 3-phase process starts with low serum estradiol and progesterone, followed by a rise in follicle stimulating hormone, and a rise in luteinizing hormone. Clinical symptoms include vasomotor ones, genitourinary ones, osteoporosis and increased incidence of bone fractures, increased incidence of thromboembolic and ischemic heart disease, and psychological symptoms of anxiety, depression, and memory loss. The age of menopause varies with socioeconomic conditions, race, parity, height, weight, skinfold thickness, lifestyle, and education. Data were obtained for this study from a sample of 1078 women from 7 sublocations in Vihiga division, Kenya. Women were aged 40-60 years. The most populous ethnic group was the Luhya. 81.6% were married, 15.6% were widowed, and 0.7% were divorced. 4 women had never been married. 75.1% had a primary school education; 18.6% had not received any formal education. 30.1% had husbands who were unskilled workers, 28.8% had husbands who were farmers, and 20.6% had husbands who were skilled workers. 1.3% had no children, and 1 woman had 17 children. The average number of children was 7.74. 9 of the nulliparous women were menopausal. The mean height was 161.1 cm. The median age at menopause was 48.28 years. Almost all women were menopausal by 55 years. The total fertility period averaged 35 years. Female life expectancy was 59 years
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG: Review of Caesarean Section deliveries at Kenyatta National Hospital 1980. M.Med Dissertation, University of Nairobi, 1982.". In: M.Med Dissertation, University of Nairobi, 1982. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG: The value of FSH, LH and prolactin assays in aetiological diagnosis of ammenorrhoea. M.Med Dissertation, University of Nairobi, 1982.". In: M.Med Dissertation, University of Nairobi, 1982. Korean Society of Crop Science and Springer; 1982. Abstract
This was a cross sectional descriptive study to discuss the median age of menopause in a rural area of Western Kenya. The broad objective of the study was to describe the demographic and biophysical characteristics of the study population and determine the age of menopause. A review of the current and medieval records shows average age of menopause has remained relatively constant at 50 years in contrast to the receeding age of menarche. A total of 1078 women aged between 40-60 years were interviewed. The majority (98.8%) were from one ethnic group, the Luhya. Of the 1078 women, 880 (81.4%) were married and 198 (18.6%) were single. The average number of children per woman was 7.74. Most of the women (75.1%) had attained primary school education. Their husbands were unskilled workers in 30.1% of the cases. The mean weight and height of the women was 60.74 kg and 161.1 cm respectively. Using methods of probit analysis, the median and modal age of menopause was found to be 48.28 years in this group of western Kenya women. If generalised for the whole country, these results suggest that an average Kenyan woman lives for over ten years beyond menopause. It is recommended that more attention should be given to the special health problems of postmenopausal population. PIP: This study describes the demographic and biophysical characteristics of rural menopausal women in Western Kenya. Menopause occurs as the gradual unresponsiveness of the human ovary to gonadotropins, premature ovarian failure at under 40 years, and menopause following surgical procedures of the uterus and ovaries. A 3-phase process starts with low serum estradiol and progesterone, followed by a rise in follicle stimulating hormone, and a rise in luteinizing hormone. Clinical symptoms include vasomotor ones, genitourinary ones, osteoporosis and increased incidence of bone fractures, increased incidence of thromboembolic and ischemic heart disease, and psychological symptoms of anxiety, depression, and memory loss. The age of menopause varies with socioeconomic conditions, race, parity, height, weight, skinfold thickness, lifestyle, and education. Data were obtained for this study from a sample of 1078 women from 7 sublocations in Vihiga division, Kenya. Women were aged 40-60 years. The most populous ethnic group was the Luhya. 81.6% were married, 15.6% were widowed, and 0.7% were divorced. 4 women had never been married. 75.1% had a primary school education; 18.6% had not received any formal education. 30.1% had husbands who were unskilled workers, 28.8% had husbands who were farmers, and 20.6% had husbands who were skilled workers. 1.3% had no children, and 1 woman had 17 children. The average number of children was 7.74. 9 of the nulliparous women were menopausal. The mean height was 161.1 cm. The median age at menopause was 48.28 years. Almost all women were menopausal by 55 years. The total fertility period averaged 35 years. Female life expectancy was 59 years
G PROFKARANJAJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "KARANJA JG: The value of FSH, LH and prolactin assays in aetiological diagnosis of ammenorrhoea. M.Med Dissertation, University of Nairobi, 1982.". In: M.Med Dissertation, University of Nairobi, 1982. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
A. PROFKETERJOSEPHKIPKORIR. "Keter, J.K.A. and J.G.A. Fiskell. 1982. Maize response to phosphate sources and rates and to auxin on two Kenya soils. Soil Crop Sci. Soc. Fla. 41 :188-192.". In: First International Workshop on Capacity Building in Soil and Water Management in Africa, Kampala, Uganda, 9-11 November, 1992. Academic Science Publishers, Nairobi, Kenya. ISBN: 9966-831-15-0. University of Nairobi Press; 1982. Abstract
OBJECTIVE: To determine the accuracy and sensitivity of diagnostic peritoneal lavage in the assessment of intra-abdominal injury using the dipstick method. DESIGN: Prospective study, involving the performance of diagnostic peritoneal lavage in the out patient department and surgical wards prior to surgical intervention. SETTING: Kenyatta National Hospital-General Surgical and Orthopaedic wards and outpatient department. The study was conducted over a duration of six months, starting from January 1995 to July 1995. RESULTS: Ninety six patients with penetrating (68) and blunt (28) abdominal trauma underwent diagnostic peritoneal lavage as evaluation of the severity of abdominal trauma. Dipstick (combur 9 strips) was used to evaluate lavage effluent for red blood cells, white blood cells, protein and bilirubin. Forty three patients had positive diagnostic peritoneal lavage (DPL) results, of which 40 (93%) had positive findings at laparatomy and three (7%) had negative findings at laparatomy. The remaining 53 patients had negative DPL results and were managed conservatively. One patient with a negative DPL result became symptomatic and had a positive laparatomy. Conservatively managed patients were discharged after 24 hours observations without any complications. DPL had an accuracy and sensitivity of 93% and specificity of 98%. CONCLUSION: Diagnostic peritoneal lavage is a cheap, safe and reliable method for assessment of abdominal trauma. The method is easy to perform by trained junior doctors in the OPD, or as a bedside procedure. Use of this method reduced negative laparotomy rate from 50% to 6.9% and average duration of stay from 6.5 days to 1.9 days. This method is recommended as a basic tool in the assessment of abdominal trauma patients.
C PROFKIPTOONJAPHETH. "Kiptoon J.C., Waiyaki P.G. and Mugera G.M. (1982): Haematological and Biochemical Changes in Cattle poisoned by Gnidia latifolia (Meisn): Toxicology journ. Vol.125 p.129-139.". In: Scientific Conference of Kenya Veterinary Association 21-22 October. 1986. ICASTOR Journal of Engineering; 1982.
WAMITILA PROFKYALLOWADI. "The Kiswahili Writer and the critic: A response to Mwenda Mbatia's polemics KISWAHILI Vol 60. Institute of Kiswahili Research, University of Dar es Salaam, Tanzania.". In: Proceedings of the African Regional Symposium on Biotechnology for Rapid Development ,Nairobi, Kenya, 17th - 21, February, 1992. pp 233-239. Bull. Environ. Contam. Toxicol; 1982. Abstract
This report concerns an outbreak that occurred during July/August 1997. Ten pigs from a herd of 181 pigs in a medium-scale, semi-closed piggery in Kiambu District, Kenya, contracted the clinical disease. The main clinical findings in affected pigs included: fever (40.5-41.8 degrees C), prostration, inappetence, dog-sitting posture, abortion, erythema and raised, firm to the touch and easily palpated light pink to dark purple diamond-shaped to square/rectangular spots on the skin around the belly and the back. Based on the pathognomonic skin lesions, a clinical diagnosis of swine erysipelas was made. The diagnosis was confirmed by the isolation of Erysipelothrix rhusiopathiae organisms from the blood and skin biopsies taken from the affected pigs. Response to treatment with a combination of procaine penicillin and dihydrostreptomycin at the dosage rate of 20,000 IU/kg body weight (based on procaine penicillin) for 3 days was good and all the affected pigs recovered fully. The farm was placed under quarantine to prevent spread of the disease
W. PROFMWANGOMBEAGNES. "Laboratory evaluation of new fungicides against coffee berry disease. Proceedings of the 1st Workshop .". In: Proceedings of the 1st Workshop . J Hum Ecol, 26(3): 163-173 (2009).; 1982. Abstract
Fusarium wilt caused by Fusarium udum Butler, is an economically important disease of pigeonpea (Cajanus cajan (L.) Mill). Information on the mechanisms of resistance to this disease in pigeonpea is limited. To study the role of vascular occlusion in wilt resistance, isolates of F.udum were inoculated onto resistant and susceptible varieties of pigeonpea and observed under light and transmission electron microscopes. The presence of F. udum in wilt susceptible plants was characterized by mycelia and conidia in the xylem vessels, plugging in some vessels, disintegration of xylem parenchyma cells in the infected areas, and the formation of cavities due to heavy colonization in the pith cortex vascular bundle. Resistance to F. udum in the roots and stems of wilt resistant plants was associated with low fungal colonization and high occlusion due to tyloses and gels in the xylem vessels. There were significant differences (P = 0:05) in the number of xylem vessels occluded by tyloses in resistant and susceptible plants with a maximum of 22.5% and 8.0% occlusion, respectively. It is probable that tyloses and gels formed as a result of F. udum interaction in wilt resistant plants are part of a resistance mechanism. Key words: Fusarium wilt,cajanus cajan, resistance, tylose, vascular occlusion
CHANDRA DRSAMANTAPURNA. "Land Characteristics, Economic Policy and Rhodesian Dualism, Africa Quarterly, Vol.20, Nos. 1 - 2 April,.". In: Annals of Tropical Medicine and Parasitology, Vol. 103, No. 3., pp. 211-220. Journal of Natural Products; 1982. Abstract
Although early diagnosis and treatment are key factors in the effective control of human African trypanosomiasis (HAT), many cases of the disease delay taking appropriate action, leading to untold suffering. As a better understanding of treatment-seeking behaviour should help in identifying the obstacles to early diagnosis and effective treatment, the treatment pathways followed by 203 former HAT cases in western Kenya and eastern Uganda have recently been explored. About 86% of the HAT cases had utilized more than two different healthcare options before being correctly diagnosed for HAT, with about 70% each using more than three different health facilities. Only about 8% of the cases reported that they had been correctly diagnosed the first time they sought treatment. Just over half (51%) of the HAT cases had been symptomatic for >2 months before being correctly diagnosed for HAT, and such time lags in diagnosis contributed to 72% of the cases receiving their first appropriate treatment only in the late stage of the disease. The likelihood of a correct diagnosis increased with the time the case had been symptomatic. These observations indicate an urgent need to build the diagnostic capacity of the primary healthcare facilities in the study area, so that all HAT cases can be identified and treated in the early stage of the disease.
PROF. SIBOE GEORGEM. "Leaf blotch and fruit rot of pomegranate.". In: FAO Plant Protection Bulletin, Vol. 30: 161-162. Taylor & Francis; 1982. Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
OKOTH PROFOKOMBODUNCAN. "Linguistics and History of Nasal Compounds in dholuo.' In Proceedings of the International Symposium on Languages and History of the Nilotic People. Collogne 1982.". In: A book review in Journal of African Languages and Linguistics Vol. 15 - 1, 80-85. CIGR Electocic Journal; 1982. Abstract
isolated from preterm neonates during the outbreak of gastroenteritis in hospital in Nairobi, Kenya, were resistance to trimethoprin-sulfathoxaxole, Chloramphenicol, oxytetracycline and ampicilin, but only a few strains were resistant to cefazolin, cefamandole, cefataximine, amikacin and nalidixic acid. Fourteen different antimicrobial resistance patterns were observed in the 229 strains of E.coli analyzed. Eighty-two percent of the EPEC strains belonged to two resistance patterns. There was no consistent relationship between palsmid profile group and antimicrobial resistance pattern, although one resistance pattern was more frequently observed in EAF-positive strins belonging to the dominant plasmid profile group. Nine percent of the EPEC strins were resistant to gentamicin compared to 37% in the non-EPEC group. No correlation was observed between administration of gentamicin and percentage of resistant strains isolated. None of the nine neonates receiving gentamicin died during the outbreak. Gentamicin resistance was observed in E.coli strains from six out of these nine neonates. Five out of fourteen neonates who received other antimicrobials, or no antibiotic at all, died. Key words: Enteropathogenic Escherichia Coli; antimicrobial resistance;
N PROFNYAGAP. "M.G. Binta, P.N. Nyaga, T.B. Tjaberg and M. Valland. Market fish hygiene in Kenya, J. Hyg. Camb. Vol. 89, 1982: 47-52.". In: Proceedings: 10th Convention, Indian Society for Veterinary Surgery, Nov. 1986. au-ibar; 1982. Abstract

According to the statements made by a number of scholars, in the 80's East African Anglophone novel, which once received a nickname of "social documentary", began to lose gradually its social commitment. Many of the writers known previously as the most active supporters of the social trend, moved their attempts to other literan areas - criminal novel ("Weapon of hunger" by Meja Mцangi, 1989), love story (Yussuf Dawood's "Off my chest", 1988), even children's literature (books for children in Gikuyu, written by Ngugi wa Thiong'o). However, in the late 80's and early 90's East African Anglophone novel stepped onto a new level of social trend, moving from "social documentary" to "social epic". The authors now are trying to sum up the historical experience of East African countries over a large time span, and to that effect appeal mostly to elaborate and spacious literary forms, such as epic novel. These authors, although chosen one and the same literary form, are showing clearly their inclinations towards different styles of writing. For example, Tanzanian author Moyez Vassanji in his novel "The gunny sack" (1989) makes a rather convincing attempt to replant on East African soil the method of "mythological writing", previously used by such author as Gabriel Garcia Marquez. The novel definitely appeals not only to local reader, but to a wider international audience; on its pages the author manages to restore not only the fate of several generations of Indian family, but even the slightest details of their mentality, using myth as one of the basic means for changing the dimensions of time and space, according to the logic of the narration. The development of Kenyan novel in the early 90's confirms also one of the main tendencies in modem literature - bridging between "elite" and popular fiction. The first attempt of an epic novel in Kenyan Anglophone literature was, oddly enough, made by the veteran of Kenyan popular fiction David Maillu in his "Broken drum" H991). The novel hardly aims the widest reading public - nevertheless, stylistically it bears distinct features of popular fiction, such as crime story, romance, etc. Popular novel in East Africa also shows certain inclination towards urgent social themes, but the authors inevitably uses the artistic means they feel most happy with - that is, the style of popular fiction. For example, the "clash of cultures" - the experience of young Africans studying abroad - is presented in the form of a picaresque ("Times beyond" by Omondi Makoloo, 1992) or love story ("The girl from Uganda" by Tengio Urrio, 1993); feministic problems are spiced with sentimentalism ("Judy the nun" by P .Waweru, 1990); the thoughts on the hardships of younger generation are guised in Bildungs roman ("The plight of succession" by a Tanzanian Prosper Rwegoshora, 1990). At the same time, some authors, who have been ploughing successfully the field of pop fiction for a few decades, show their interest in more elaborate literary forms ("Dedan Kimathi: the real story" by Samuel Kaluga, 1990). All the mentioned facts do not allow us to state that the division into popular and elite novel will disappear within the foreseeable future. However, the most interesting developments seem to take place precisely in the field of bridging between these two branches of East African fiction.

N PROFNYAGAP. "M.G. Binta, P.N. Nyaga, T.B. Tjaberg and M. Valland.Vibrio parahaemolyticus: Occurence in marine sea fish. Shellfi6h, water and sediment in Kenya. E. Afric. Med. Journ. Yol. 59 (7),1982: 442-445.". In: Proceedings: 10th Convention, Indian Society for Veterinary Surgery, Nov. 1986. au-ibar; 1982. Abstract

According to the statements made by a number of scholars, in the 80's East African Anglophone novel, which once received a nickname of "social documentary", began to lose gradually its social commitment. Many of the writers known previously as the most active supporters of the social trend, moved their attempts to other literan areas - criminal novel ("Weapon of hunger" by Meja Mцangi, 1989), love story (Yussuf Dawood's "Off my chest", 1988), even children's literature (books for children in Gikuyu, written by Ngugi wa Thiong'o). However, in the late 80's and early 90's East African Anglophone novel stepped onto a new level of social trend, moving from "social documentary" to "social epic". The authors now are trying to sum up the historical experience of East African countries over a large time span, and to that effect appeal mostly to elaborate and spacious literary forms, such as epic novel. These authors, although chosen one and the same literary form, are showing clearly their inclinations towards different styles of writing. For example, Tanzanian author Moyez Vassanji in his novel "The gunny sack" (1989) makes a rather convincing attempt to replant on East African soil the method of "mythological writing", previously used by such author as Gabriel Garcia Marquez. The novel definitely appeals not only to local reader, but to a wider international audience; on its pages the author manages to restore not only the fate of several generations of Indian family, but even the slightest details of their mentality, using myth as one of the basic means for changing the dimensions of time and space, according to the logic of the narration. The development of Kenyan novel in the early 90's confirms also one of the main tendencies in modem literature - bridging between "elite" and popular fiction. The first attempt of an epic novel in Kenyan Anglophone literature was, oddly enough, made by the veteran of Kenyan popular fiction David Maillu in his "Broken drum" H991). The novel hardly aims the widest reading public - nevertheless, stylistically it bears distinct features of popular fiction, such as crime story, romance, etc. Popular novel in East Africa also shows certain inclination towards urgent social themes, but the authors inevitably uses the artistic means they feel most happy with - that is, the style of popular fiction. For example, the "clash of cultures" - the experience of young Africans studying abroad - is presented in the form of a picaresque ("Times beyond" by Omondi Makoloo, 1992) or love story ("The girl from Uganda" by Tengio Urrio, 1993); feministic problems are spiced with sentimentalism ("Judy the nun" by P .Waweru, 1990); the thoughts on the hardships of younger generation are guised in Bildungs roman ("The plight of succession" by a Tanzanian Prosper Rwegoshora, 1990). At the same time, some authors, who have been ploughing successfully the field of pop fiction for a few decades, show their interest in more elaborate literary forms ("Dedan Kimathi: the real story" by Samuel Kaluga, 1990). All the mentioned facts do not allow us to state that the division into popular and elite novel will disappear within the foreseeable future. However, the most interesting developments seem to take place precisely in the field of bridging between these two branches of East African fiction.

W MRMAINAFRANCIS, S PROFKIGONDUCHRISTINE. "Maina F.W., Mati J.K.G., Sekadde-Kigondu C.B. .". In: J. Obs/Gyn. East Central Africa 1:126(1982). uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
W MRMAINAFRANCIS, S PROFKIGONDUCHRISTINE. "Maina F.W., Mati J.K.G., Sekadde-Kigondu C.B. .". In: J. Obs/Gyn. East Central Africa 1:126(1982). EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
K PROFMAITAICHARLES. "Maitai CK.Bioavailability of drugs. East Afr Med J. 1982 Aug;59(8):503-4.". In: East Afr Med J. 1982 Aug;59(8):503-4. African Crop Science Society; 1982. Abstract
Cathinone, a potent psychostimulant isolated from young shoots of Catha edulis was given to four human volunteers. Examination of urine collected from the volunteers at predetermined intervals showed the presence of unchanged cathinone, d-norpseudoephedrine, and two unidentified basic substances. The observed biotransformation of cathinone to the less potent psychostimulant, d-norpseudoephedrine involves reduction of a ketone group to alcohol, a common metabolic pathway in humans.
OLE PROFMALOIYGEOFFREYM. "MALOIY, G.M.O.(1982) Elephant. In: The World Book Encyclopaedia, Vol. 6, pp. 178-180.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
OLE PROFMALOIYGEOFFREYM. "MALOIY, G.M.O.(1982) Physiology and ecology of the topi antelope in Masai Mara Game Reserve, Kenya. National Geographic Research Reports 13, 419-429.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
OLE PROFMALOIYGEOFFREYM. "MALOIY, G.M.O., CLEMENS, E.T. and KAMAU, J.M.Z. (1982) Aspects of digestion and in vitro rumen fermentation rate in six species of East African wild ruminants. Journal of Zoology London 197, 245-253.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
OLE PROFMALOIYGEOFFREYM. "MALOIY, G.M.O., KAMAU, J.M.Z., SHKOLNIK, A., MEIR, M. and ARIELI, R.(1982) Thermoregulation and metabolism in a small desert carnivore: the fennec fox (Fennecus zerda). Journal of Zoology London 198, 279-292.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
P. PROFMUREITHILEOPOLD. "Manpower and Employment in Kenya An Overview. Paper written with F.M Muhindi for the Ministry of Higher Education's Pre-investment Study on Business Education.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1982. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
P. PROFMUREITHILEOPOLD. "Market Study Report on Bamba - Ganze -Vitengeni water Supply Project: Kilifi District Kenya Ministry of Water Development with S.M Ngola.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1982. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
S PROFMASINDEMICHAEL. "Masinde, M. S. Hyphema study at Kenyatta National Hospital East. African Journal of Ophthalmology 6: 32 .". In: African Journal of Ophthalmology 6: 32 .; 1982. Abstract
OBJECTIVE: To determine the prevalence of Xerophthalmia among Kenyan children aged four to seven years in high risk using Conjuctival Impression Cytology and transfer. DESIGN: A cross sectional community based study. SETTING: Mathare slum in Nairobi and Tiva/Ithiani area of Kitui. SUBJECTS: Children aged four to seven years residing in the above areas were assessed for both clinical and cytological features of vitamin A deficiency. RESULTS: Of the 342 children included in this study, 316 (92.0%) were normal, five (1.5%) had XN, 19 (5.9% had XIA and two (0.6%) had XIB. No signs of corneal Xerophthalmia were seen in this study. Conjuctival impression cytology and transfer (CICT) was used to asses for squamous metaplastic changes associated with Vitamin A deficiency (VAD). Seventy five (23.1%) of the children were normal by CICT while 249 (76.9%) were abnormal. In comparing the two areas of study, only 13.2% of the children in Mathare had normal CICT compared to 50% in Kitui. For each of the age groups studied there was significant difference between the two areas with children from Mathare being more deficient than those from Kitui. CONCLUSION: VAD is a significant health problem in the high risk areas assessed by CICT in this study.
ONYALO PROFYAMBOMAURI. "Mauri Yambo, "Socio-Economic Factors in the Development and Diffusion of New Wood/Charcoal Stoves: Some Theoretical and Methodological Considerations." In African Journal of Sociology, Vol. II, No. 2, November, 1982 (pp. 159-185).". In: In POST (A journal of the Kenya National Academy of Sciences) Volume XI Number 1 of 1986. University of Nairobi Press, Open and Distance Learning; 1982. Abstract
{ This paper proposes a new theory, a theory of the memetic sphere; and outlines its main features, based on library research. In Dawkinsian parlance, memes are ideas, phrases and sentences with a gene-like capacity to replicate. The theory maps the chain-reaction in the form of which this replication becomes what we know as the information explosion, and attempts to show what lies beyond the explosion. No known study has highlighted the similitudes between the memetic sphere and the physical universe. The theory is summarized in an Einsteinian equation
C PROFKIPTOONJAPHETH. "Mbiuki S.M. and Kiptoon J.C. (1982): Fibrosarcoma in an Avrshire Heifer .". In: Scientific Conference of Kenya Veterinary Association 21-22 October. 1986. ICASTOR Journal of Engineering; 1982.
MUNGAI DRMBUGUAPAUL. "Mbugua P M Thairu K and Telang B V (1982): Identification and estimation of a cholinomimetic substance in the venom of Dendroaspis polylepis Res. Commun. Chem. Pathol. Pharmacol. 36: 187-.". In: Federation of Analytical Chemistry and Spectroscopy Society (FACSS) XV, Boston, November 1988. AWC and FES; 1982. Abstract

Mbugua PM, Thairu K, Ng'ang'a JN, Telang BV.

A cholinomimetic substance was isolated from desiccated venom of Dendroaspis polylepis by one-dimensional ascending paper chromatography. The migratory and staining properties of the substance were compared with those of standard acetylcholine. Pharmacological and biochemical identification was carried out on various in vitro and in vivo biological test objects as well as with high-voltage paper electrophoresis. The assay of the cholinomimetic substance was done on both superfused guinea pig ileum and hamster stomach strips. The cholinomimetic substance content was 2.44 - 3.46mg/0.96gm of total protein in the desiccated venom.

PMID: 7100627 [PubMed - indexed for MEDLINE]

MUNGAI DRMBUGUAPAUL. "Mbugua P M Thairu K and Telang B V (1982): Neuropharmacological studies of certain snake venoms Indian J Pharmacol 14: 115-.". In: Federation of Analytical Chemistry and Spectroscopy Society (FACSS) XV, Boston, November 1988. AWC and FES; 1982. Abstract

Mbugua PM, Thairu K, Ng'ang'a JN, Telang BV.

A cholinomimetic substance was isolated from desiccated venom of Dendroaspis polylepis by one-dimensional ascending paper chromatography. The migratory and staining properties of the substance were compared with those of standard acetylcholine. Pharmacological and biochemical identification was carried out on various in vitro and in vivo biological test objects as well as with high-voltage paper electrophoresis. The assay of the cholinomimetic substance was done on both superfused guinea pig ileum and hamster stomach strips. The cholinomimetic substance content was 2.44 - 3.46mg/0.96gm of total protein in the desiccated venom.

PMID: 7100627 [PubMed - indexed for MEDLINE]

DANIEL DRNJAI, SAMSON PROFMEMEJULIUS. "Meme J. S., Njai D., Kyambi, Kungu A. Antral mucosal Diaphragm. An obstructing lesion of the stomach. E. Afr. Med. J. 59: 161, 1982.". In: E. Afr. Med. J. 59: 161, 1982. au-ibar; 1982. Abstract
Department of Veterinary Medicine, Faculty of Veterinary Medicine, Makerere University, Kampala, Uganda. Pulmonary oedema is a common sign of East Coast fever (ECF, Theileria parva infection) of cattle. A trial was conducted on farms in Uganda to compare a product containing both the antitheilerial compound parvaquone and the diuretic compound frusemide with one containing only parvaquone, in the treatment of ECF. The trial involved 40 clinical cases of ECF, some of them complicated by other infections, in cattle of all ages and on several farms. Confirmed cases were treated with either parvaquone+frusemide (P+F) or parvaquone alone (P). Survival after treatment with P+F was 77% compared with 71% with P. Five of the 10 fatalities were complicated cases. The cure rate for severe but uncomplicated ECF was 89% with P+F and 40% with P. Pulmonary signs were resolved within 24-48 h after treatment with P+F and clinical recovery was noticeably more rapid than with P. The antiparasitic effect of the two treatments was similar. P+F could be particularly useful when reporting, diagnosis or laboratory confirmation of ECF is delayed, because advanced cases are more likely to be encountered under these circumstances.
M. PROFKYAMBIJ. "Meme JS, Njai DM, Kyambi JM, Kung'u A.Antral mucosal diaphragm: an obstructing lesion of the stomach.East Afr Med J. 1982 Feb;59(2):161-4.". In: East Afr Med J. 1982 Feb;59(2):161-4. East African Orthopaedic Journal; 1982. Abstract
At the beginning of the century, splenectomy was used in the treatment of kala-azar, but now is rarely needed, the major indication being for drug resistant kala-azar. Inadvertent splenectomy prior to the diagnosis of kala-azar continues to occur, probably because of a reluctance to perform splenic aspiration in the investigation of splenomegaly. Five Kenyan children underwent splenectomy for drug resistant kala-azar. All were immediately improved, but one died of overwhelming post splenectomy infection (OPSI) two months later and another of a malignant lymphoma seven months after surgery. The other three patients appear to be cured. Splenectomy was considered in a sixth child with kala-azar because of a Salmonella abscess in the spleen, but the abscess ruptured catastrophically before surgery could be arranged.
ODERA PROFALILAPATRICK. "Migot-Adholla, S.E., Ruigu, G., Socio-Economic Evaluation of Small Scale Village Irrigation Projects in Tana south, Coast Province, SSIU, Ministry of Agriculture, Nairobi, May 1982.". In: The Development of the National Economy Colourprint Ltd. Nairobi, 1993. International Union of Crystallography; 1982. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
MITEMA PROFSEO. "Mitema, E.S. (1982). Effects of chronic chloramphenicol administration on the bovine hematology and bone marrow. Vet. Hum. Toxicol. 24 S: 162-166.". In: journal. BEP Electronic Press; 1982. Abstract
Two groups of 6 rats each received subcutaneous injections of 2.3 mg/kg or 5.0 mg/kg of quinuronium, respectively, on two consecutive days, while 5 rats injected with physiological saline served as controls. Clinical signs of muscular tremors, jumps, enlarged and hyperemic eyeballs, lacrimation, depression and anorexia were observed following administration of quinuronium. One rat receiving 5 mg/kg died before termination of the study. When killed 48 h after the first injection, the quinuronium-treated rats had a higher liver weight/body weight ratio compared to the controls. Quinuronium resulted in hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH). The present findings suggest that glutathione depletion does not seem to be involved in quinuronium hepatotoxicity.
MITEMA PROFSEO. "Mitema, E.S. (1982). The influence of Quinuronium sulfate on Serum Glutamic Oxaloacetictrasnasaminase (SGOT) in cattle. Acta Vet. (Beorgrad) 32: 307-312.". In: journal. BEP Electronic Press; 1982. Abstract
Two groups of 6 rats each received subcutaneous injections of 2.3 mg/kg or 5.0 mg/kg of quinuronium, respectively, on two consecutive days, while 5 rats injected with physiological saline served as controls. Clinical signs of muscular tremors, jumps, enlarged and hyperemic eyeballs, lacrimation, depression and anorexia were observed following administration of quinuronium. One rat receiving 5 mg/kg died before termination of the study. When killed 48 h after the first injection, the quinuronium-treated rats had a higher liver weight/body weight ratio compared to the controls. Quinuronium resulted in hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH). The present findings suggest that glutathione depletion does not seem to be involved in quinuronium hepatotoxicity.
S PROFMASINDEMICHAEL. "Mnjalla, N., Masinde M. S. Trachoma survey in primary schools in Machakos District, Kenya E. African of Ophthalmology 5: 25 .". In: Kenya E. African of Ophthalmology 5: 25 .; 1982. Abstract
OBJECTIVE: To determine the prevalence of Xerophthalmia among Kenyan children aged four to seven years in high risk using Conjuctival Impression Cytology and transfer. DESIGN: A cross sectional community based study. SETTING: Mathare slum in Nairobi and Tiva/Ithiani area of Kitui. SUBJECTS: Children aged four to seven years residing in the above areas were assessed for both clinical and cytological features of vitamin A deficiency. RESULTS: Of the 342 children included in this study, 316 (92.0%) were normal, five (1.5%) had XN, 19 (5.9% had XIA and two (0.6%) had XIB. No signs of corneal Xerophthalmia were seen in this study. Conjuctival impression cytology and transfer (CICT) was used to asses for squamous metaplastic changes associated with Vitamin A deficiency (VAD). Seventy five (23.1%) of the children were normal by CICT while 249 (76.9%) were abnormal. In comparing the two areas of study, only 13.2% of the children in Mathare had normal CICT compared to 50% in Kitui. For each of the age groups studied there was significant difference between the two areas with children from Mathare being more deficient than those from Kitui. CONCLUSION: VAD is a significant health problem in the high risk areas assessed by CICT in this study.
MWANGI DRMUCHEMIG. "Muchemi G.K.M. (1982). A study of Muscle Cysticercosis in Wild animals of Kenya. MSc thesis University of Guelph, Ontario Canada.". In: East African Agricultural and Forestry Journal. EAMJ; 1982. Abstract
Department of Medical Microbiology, College of Health Sciences, University of Nairobi, Nairobi. Four hundred and thirty six pupils in two primary schools in Kibwezi, Kenya aged between seven and sixteen years and positive for S. mansoni were treated as follows: 320 pupils with a single dose of praziquantel at 40 mg/kg body weight and 116 controls with a placebo. Immediate and delayed side effects of praziquantel were observed. The main side-effects were abdominal pain (36.3%), headache (35.3%) and nausea (13.1%). There was correlation between frequencies of these side-effects and intensity of infection measured as eggs per gram of faeces. Other side-effects included dizziness (9.7%), fever (7.8%), urticaria and bloody diarrhoea. Overall, the side-effects of praziquantel were mild and transient, and did not require any intervention. For ethical reasons, all pupils who served as controls were treated with praziquantel after the study. PMID: 8898462 [PubMed - indexed for MEDLINE]
NDEGWA DRGICHUKIFRANCIS. "Muchiri, G. and Gichuki F.N. 1982. ."; 1982. Abstract
n/a
C PROFKIPTOONJAPHETH. "Mugera G.M. Kiptoon J.C. and Waiyaki P.G. (1982): Studies on the Toxicity of Gndia latifolia (Meisn) in cattle. Bull Anim. Hlth. & Prod. Afr. Vol.30.250-257.". In: Scientific Conference of Kenya Veterinary Association 21-22 October. 1986. ICASTOR Journal of Engineering; 1982.
S PROFKIGONDUCHRISTINE. "Mukasa F., Mati J.K.G., Sekadde-Kigondu C.B., Lequin R.M. J. Obstet. Gynaecol. E. Central Afr. 1:160, 1982 Pituitary reserve for gonadotrophin and prolactin in women using long term depo-provera.". In: J. Obstet. Gynaecol. E. Central Afr. 1:160, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Mukasa FR, Sekadde-kigondu CB, Mati JK, Njoroge JK. The pituitary reserve for gonadotrophins and prolactin in women under long-term use of depo-medroxyprogesterone acetate (DMPA) as a contraceptive. J Obstet Gynaecol East Cent Africa. 1982 Dec;1(4):160-3.". In: J. Obs/Gyn. East Central Africa 1:126(1982). uon press; 1982. Abstract
PIP: Pituitary reserve was assessed in women who had used depo-medroxyprogesterone acetate (DMPA) for 1, 5 and 10 years, and their responses were compared to 2 control groups–IUD users and noncontraceptive users. 100 ug GnRH and 200ug TRH were injected as a bolus and the Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Prolaction (PRL) responses noted. The basal PRL levels were similar in all groups. The PRL response to stimulation was significantly greater among 5 and 10 year DMPA users and also IUD users. The mean basal levels of LH were within the normal follicular phase range in all groups. However, the response to stimulation was significantly higher among 1 and 5 year DMPA users when compared with noncontraceptive users. The basal serum FSH levels in both the study and control groups were comparable to those of normally cycling women in the follicular phase. The response to stimulation was greater in the 10 year DMPA users when compared to both the noncontraceptive users and IUD users. The study shows that basal levels of FSH, LH and PRL were similar in the study and control groups. The observed amplified response to stimulation among longterm DMPA users could be the result of failure of gonadotropin cyclic release, possibly resulting in increased pituitary reserves.
MUNGE PROFMUKUNYAD. "Mukunya, D.M. 1982. Development of crop varieties for disease resistance.". In: Proceedings of the third FAO/SIDA seminar on . Plant Molecular Biology Reporter Vol. 27, pp. 79-85.; 1982. Abstract
The gene Q13L coding for the Capripoxvirus group specific structural protein P32 was expressed in Escherichia coli using plasmid pGEX-2T as a fusion protein with glutathione-s-transferase and purified on glutathione sepharose affinity chromatography column. The protein was then employed for diagnosis of sheeppox, goatpox and lumpyskin disease, by a latex agglutination test (LAT) using the purified P32 antigen and guinea pig detector antiserum raised against the P32 antigen. The LAT and virus neutralization test (VNT) were used to screen one hundred livestock field sera for antibodies to Capripoxvirus, in comparison the LAT was simpler, rapid and 23% more sensitive than the VNT. In addition the LAT was found to be specific for Carpripoxvirus because it did not pick antibodies to Orthopoxvirus and Parapoxvirus. The LA test can be taken for a simple and quick diagnostic tool for primary screening of Carpripoxvirus infection and will reduce the reliance of diagnostic laboratories on tissue culture facilities. Keywords: Carpripox, latex agglutination test, attachment gene J. Trop. Microbiol. Biotechnol. Vol. 3 (2) 2007: pp. 36-43
MUNGE PROFMUKUNYAD. "Mukunya, D.M. 1982. UNDP/FAO Evaluation study on National Agricultural Research, Kenya 195 +35 Annex tables, FAO, ROME.". In: Proceedings of the Workshop on root and Tuber crops held in Burundi. IITA. Ibadan, Nigeria. Plant Molecular Biology Reporter Vol. 27, pp. 79-85.; 1982. Abstract
The gene Q13L coding for the Capripoxvirus group specific structural protein P32 was expressed in Escherichia coli using plasmid pGEX-2T as a fusion protein with glutathione-s-transferase and purified on glutathione sepharose affinity chromatography column. The protein was then employed for diagnosis of sheeppox, goatpox and lumpyskin disease, by a latex agglutination test (LAT) using the purified P32 antigen and guinea pig detector antiserum raised against the P32 antigen. The LAT and virus neutralization test (VNT) were used to screen one hundred livestock field sera for antibodies to Capripoxvirus, in comparison the LAT was simpler, rapid and 23% more sensitive than the VNT. In addition the LAT was found to be specific for Carpripoxvirus because it did not pick antibodies to Orthopoxvirus and Parapoxvirus. The LA test can be taken for a simple and quick diagnostic tool for primary screening of Carpripoxvirus infection and will reduce the reliance of diagnostic laboratories on tissue culture facilities. Keywords: Carpripox, latex agglutination test, attachment gene J. Trop. Microbiol. Biotechnol. Vol. 3 (2) 2007: pp. 36-43
MUNGE PROFMUKUNYAD. "Mukunya, D.M. et al. 1982. Citrus greening disease in Kenya and recommendations for its control. Ministry of Agriculture Publication. 128 p.". In: Proceedings of the Workshop on root and Tuber crops held in Burundi. IITA. Ibadan, Nigeria. Plant Molecular Biology Reporter Vol. 27, pp. 79-85.; 1982. Abstract
The gene Q13L coding for the Capripoxvirus group specific structural protein P32 was expressed in Escherichia coli using plasmid pGEX-2T as a fusion protein with glutathione-s-transferase and purified on glutathione sepharose affinity chromatography column. The protein was then employed for diagnosis of sheeppox, goatpox and lumpyskin disease, by a latex agglutination test (LAT) using the purified P32 antigen and guinea pig detector antiserum raised against the P32 antigen. The LAT and virus neutralization test (VNT) were used to screen one hundred livestock field sera for antibodies to Capripoxvirus, in comparison the LAT was simpler, rapid and 23% more sensitive than the VNT. In addition the LAT was found to be specific for Carpripoxvirus because it did not pick antibodies to Orthopoxvirus and Parapoxvirus. The LA test can be taken for a simple and quick diagnostic tool for primary screening of Carpripoxvirus infection and will reduce the reliance of diagnostic laboratories on tissue culture facilities. Keywords: Carpripox, latex agglutination test, attachment gene J. Trop. Microbiol. Biotechnol. Vol. 3 (2) 2007: pp. 36-43
A DRMASIGAMARY. "Muriithi, H., Masiga, M.A., Chindia, M.L. Paediatric dental injuries at Kenyatta N. Hospital.(EAMJ 82: 592-597).". In: (EAMJ 82: 592-597). University of Nairobi.; 1982. Abstract

Four hundred and forty-six children attending nursery schools in Nairobi were examined for caries and gingivitis. Assessment of social class was based on the occupation of the head of the child's household. Amongst 3-year-old children, 62% were caries-free and the mean dmft was 1.35. Amongst 5-year-olds 50% were caries-free and the mean dmft was 1.88. Thirty-seven per cent of the children had evidence of gingivitis, with the proportion changing little with age. There was no evidence of either caries or gingivitis being significantly related to social class, although children in the higher classes had more filled teeth.

A. PROFWAMOLAISAAC. "Mutanda LN, WAMOLA I.A and Kaviti JN. The Relationship Between the most commonly occurring Shigella serotypes and ages of patients. Medicom 4: 147, 1982.". In: Medicom 4: 147, 1982. IBIMA Publishing; 1982. Abstract
A study that devised a modified method of reporting antibiotic sensitivity results was undertaken. Enterobacteriaceae and Gram positive cocci were tested for drug sensitivity by a disc diffusion method. Zones of bacterial growth inhibition were measured, dividing the isolates into four groups: the highly sensitive, the moderately sensitive, the slightly sensitive and the resistant ones. The slightly sensitive isolates were taken as indicators of antibiotic resistance acquisition. By that system, when more than 50% of the isolates fell into the slightly and resistant groups, that meant that the antibiotic concerned would be discontinued for some time until the bacteria reverted to being moderately sensitive. The study also provided a method of making antibiotic discs from local blotting papers, and a sample of a form on which antibiotic sensitivity results could be recorded was presented. The method is considered to be easy and very appropriate for developing countries in detecting gradual and abrupt acquisition of antibiotic resistance by bacteria.
R PROFMUTIGAERASTUS. "Mutiga, E.R. and Baker A.A. 1982. Superovulation of sheep using PMSG at different days of the oestrus cycle.". In: Proc. 2nd World Confr. on Embryo Transfer and vitro fertilization. Annecy France. Abst. Erick Onyango Odada; 1982. Abstract
Data relating to reproductive parameters of German shepherd bitches were collected from registered German shepherd dog (GSD) breeders with information kept over a 15-year period (1982-1997). The information obtained was verified using the East African Kennel Club records. A total of 594 bitches from 280 breeders were recorded. From these, 798 heats were observed, 594 of which were used for breeding, resulting in 3592 puppies. The mean age at puberty was 519.0 +/- 41 days. Heats occurred throughout the year, although significantly (P < 0.05) higher and lower incidences were observed in October and April respectively Pregnancy significantly (P < 0.01) increased interoestrous interval, which was 247.8 +/- 99.6 and 183 +/- 52 days among bred/pregnant and non-bred bitches respectively. Most bitches in oestrus (73.7%) were bred, and breeding was carried out throughout the year, with a distribution closely related to that of heat incidence. Subsequently, whelping occurred throughout the year, and 95.5% of the bitches that were mated whelped. A mean gestation period of 60.6 +/- 5.1 days was observed. The mean litter size was 6.4 +/- 0.4 puppies, and did not differ significantly between months. The preweaning losses were low, with 2.3% stillbirths, 0.9% culls and 11.4% mortalities.
R PROFMUTIGAERASTUS. "Mutiga, E.R. and Baker, A.A. 1982B. Ovarian response, ova recovery and fertility in Merino ewes superovulated either during the luteal phase of their oestrous cycle of after intravaginal progestagen treatment. Theriogenology 17 (5) : 537-544.". In: Disc and Innov. Acd. Sci. Publ. Vol.1 No.4, 39-43 (1989). Erick Onyango Odada; 1982. Abstract
Data relating to reproductive parameters of German shepherd bitches were collected from registered German shepherd dog (GSD) breeders with information kept over a 15-year period (1982-1997). The information obtained was verified using the East African Kennel Club records. A total of 594 bitches from 280 breeders were recorded. From these, 798 heats were observed, 594 of which were used for breeding, resulting in 3592 puppies. The mean age at puberty was 519.0 +/- 41 days. Heats occurred throughout the year, although significantly (P < 0.05) higher and lower incidences were observed in October and April respectively Pregnancy significantly (P < 0.01) increased interoestrous interval, which was 247.8 +/- 99.6 and 183 +/- 52 days among bred/pregnant and non-bred bitches respectively. Most bitches in oestrus (73.7%) were bred, and breeding was carried out throughout the year, with a distribution closely related to that of heat incidence. Subsequently, whelping occurred throughout the year, and 95.5% of the bitches that were mated whelped. A mean gestation period of 60.6 +/- 5.1 days was observed. The mean litter size was 6.4 +/- 0.4 puppies, and did not differ significantly between months. The preweaning losses were low, with 2.3% stillbirths, 0.9% culls and 11.4% mortalities.
R PROFMUTIGAERASTUS. "Mutiga, E.R. and Baker, AA. 1982a. Superovulatory response in Merino ewes to three PMSG dosage levels. Theriogenology 17 (1). 100 abst.". In: Disc and Innov. Acd. Sci. Publ. Vol.1 No.4, 39-43 (1989). Erick Onyango Odada; 1982. Abstract
Data relating to reproductive parameters of German shepherd bitches were collected from registered German shepherd dog (GSD) breeders with information kept over a 15-year period (1982-1997). The information obtained was verified using the East African Kennel Club records. A total of 594 bitches from 280 breeders were recorded. From these, 798 heats were observed, 594 of which were used for breeding, resulting in 3592 puppies. The mean age at puberty was 519.0 +/- 41 days. Heats occurred throughout the year, although significantly (P < 0.05) higher and lower incidences were observed in October and April respectively Pregnancy significantly (P < 0.01) increased interoestrous interval, which was 247.8 +/- 99.6 and 183 +/- 52 days among bred/pregnant and non-bred bitches respectively. Most bitches in oestrus (73.7%) were bred, and breeding was carried out throughout the year, with a distribution closely related to that of heat incidence. Subsequently, whelping occurred throughout the year, and 95.5% of the bitches that were mated whelped. A mean gestation period of 60.6 +/- 5.1 days was observed. The mean litter size was 6.4 +/- 0.4 puppies, and did not differ significantly between months. The preweaning losses were low, with 2.3% stillbirths, 0.9% culls and 11.4% mortalities.
A MRMUTULIDANIEL, A MRMUTULIDANIEL. "Mutuli, D.A. (1982) The general position paper for the coffee factories section of the Ministry of Agriculture. Government Working Paper (unpublished).". In: World Employment Programme Research Working Papers, No. 45. Geneva: International Labour Office. Cambridge: Cambridge University Press.; 1982. Abstract

A description is given of a novel liquid phase immunoassay for the measurement of testosterone in peripheral venous plasma from men and women. The procedure involves: (i) competitive binding of the analyte and tritiated antigen to specific antibodies; (ii) enzymatic conjugation of the free ligand with glucuronic acid; and (iii) separation of the antibody-bound and free ligand by partition of the reactants into an organic and aqueous phase. The technique has been called ligand differentiation immunoassay (LIDIA). The mean sensitivity was 5 pg/tube (equivalent to 0.35 nmol/l female plasma; 0.87 nmol/l male plasma). The mean reagent blank (+/- SD) was 0.24 (0.12) nmol/l female plasma; 0.61 (0.30) nmol/l male plasma. A precision profile gave values less than 50%; the within batch variation was less than 8.3% and the between batch variation over three months was 12.3%. An accuracy profile between the second and penultimate points on the calibration curve gave values between 77 and 103%. The correlation coefficient 'r' between LIDIA and a heterogeneous radioimmunoassay was 0.92 when applied to plasma from men and 0.95 to samples from women.

S PROFKIGONDUCHRISTINE. "Mwalali P.N., Mati J.K.G., Sekadde-Kigondu C.B., Lequin R.M., J. Obstet. Gynaecol. E. Central Africa,1:64, 1982 The Effects of GnRH and TRH on pituitary secretion of FSH, LH and PRL in Normal Kenyan Males.". In: J. Obstet. Gynaecol. E. Central Africa,1:64, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
PROF. MWANGI RICHARDW. "Mwangi, R.W. (1982). Locust antifeedant activity from Melia volkensii. Entomol. Exp. Appl. 32, 277-280.". In: Proc. 3 int. Conf. trop. climates. 235-237 (1985). The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1982.
S PROFKIGONDUCHRISTINE. "Nana O.F., Mati J.K.G., Lequin R.M., Sekadde-Kigondu C.B.,J. Obster. Gynaecol. E. and Central Africa, 1:1, 42, 1982:Pituitary-Ovarian Function during and afterpelvic Irradiation for carcinoma of the cervix.". In: Obster. Gynaecol. E. and Central Africa, 1:1, 42, 1982:. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Ndeto G.W., Mati J.K.G., Sekadde-Kigondu C.B., et al J. Obstet. Gynaecol. E. Central Afr. 1:58, 1982 Prolactin release in subjects with uterine fibroid.". In: J. Obstet. Gynaecol. E. Central Afr. 1:58, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Ndeto G.W.T., Mati J.K.G., Sekadde-Kigondu C.B., Lequin R.M. Prolactin response in patients with hypertensive disease in pregnancy J. Obstet. Gynaecol. E. Central Afr. 1:166, 1982.". In: J. Obstet. Gynaecol. E. Central Afr. 1:166, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
KURIA PROFMBUGUASAMUEL. "Nitrates/nitrites and Nitrosamines in foodstuff, and their public health implications. KIFST bulletin No. May 1982.". In: AFS/UNU workshop on Development of Indigenous Fermented foods and food technology in Africa, 14 18 Octobe3r 1985. Douala Cameroon. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1982. Abstract
Nine patients with acute liver failure due to Plasmodium falciparum liver injury admitted to the Rajgarhia Liver Unit of the All-India Institute of Medical Sciences during 1982-84 are presented. The liver was palpable in all the patients, and eight had splenomegaly. Investigations revealed mild to moderate abnormality in liver function tests. All were negative for the markers of acute infection due to hepatitis A and B viruses. Blood film examination showed P. falciparum alone in seven and along with P. vivax in the remaining two patients. Liver histology, which was identical in all eight patients where liver biopsy was done, showed centrizonal necrosis and hyperplastic Kupffer cells loaded with malarial pigment. All the patients recovered with specific anti-malarial and supportive treatment. Our observations suggest that malaria due to P. falciparum may present as jaundice and encephalopathy which stimulates acute hepatic failure due to fulminant hepatitis.
L. PROFWANJALACHRISTOPHER. "Notes on Grace Ogot's Land Without Thunder for O-levels, Authored, Nairobi.". In: Nyange Publishers.; 1982. Abstract

A random sample survey using personal interviews was conducted in Machakos and Makueni Districts of Kenya in 1992 to estimate the level of rabies vaccination of the dog population. To substantiate the results of the interviews, a sample of the surveyed dogs 3 months old and above were bled for serum rabies antibody determination using an inhibition enzyme immunoassay (INH EIA). Of the 266 surveyed 3 months old and above, only 29% (77/266) were reportedly vaccinated against rabies. Out of the 197 dog sera titrated for rabies antibody, only 29% (57/197) had detectable antibodies and only 16% (32/197) had antibody tires equal to or greater than the threshold considered protective of 0.5 I.U/ml. There was a strong positive association between a history of previous vaccination and the detection of rabies antibodies. Of 133 dogs with no history of previous vaccination, 20% (26/133) had detectable antibodies. With the rabies incidence in Machakos and Makueni Districts still unacceptably high, the level of vaccination estimated in this survey is clearly inadequate for rabies control and measures designed to increase it are discussed.

MUCHAI PROFKAGIKOM, MWANGI PROFGATHUMAJ. "Nyaga, P.N., Kagiko, M.M. and Gathuma, J.M. (1982). Milk hygiene in nomadic herds in Kenya evaluated by bacterial isolation, in vitro bacterial viability trials in traditionally fermented milk and drug sensitivity. Bull. Anim. Hlth. Prod. Afr. 30 (1) 19 .". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
MUCHAI PROFKAGIKOM, MWANGI PROFGATHUMAJ. "Nyaga, P.N., Kagiko, M.M. and Gathuma, J.M. (1982). Milk hygiene in nomadic herds in Kenya evaluated by bacterial isolation, in vitro bacterial viability trials in traditionally fermented milk and drug sensitivity. Bull. Anim. Hlth. Prod. Afr. 30 (1) 19 .". In: journal. au-ibar; 1982. Abstract
Antisera to thermostable muscle antigens from 13 wild animals: Buffalo, Waterbuck, Bushbuck, Eland, Oryx, Kongoni, Bushpig, Warthog, Topi, Thomson’s gazelle, Grant’s gazelle, Sheep, Pig, Horse, Camel & Dog, were raised in rabbits and/or goats. Absorptions of the antisera with copolymerized pooled serum from the 20 species and the thermostable muscle antigens rendered most of the antisera mmonospecific. It was possible to identify the species of origin of saline extracts of both cooked and fresh meat samples in immunodiffusion tests. The method is promising for use in identification of the species origin of fresh and cooked animal meats.
O PROFOBELARTHUR. "Obel AO. Goitre and fluorosis in Kenya. East Afr Med J. 1982 Jun;59(6):363-5. No abstract available.". In: East Afr Med J. 1982 Jun;59(6):363-5. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Goitre and fluorosis in Kenya. East Afr Med J. 1982 Jun;59(6):363-5. No abstract available.". In: East Afr Med J. 1982 Jun;59(6):363-5. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

O PROFOBELARTHUR. "Obel AO. Management of chronic pain: practical therapeutics. East Afr Med J. 1982 Jul;59(7):429-34. No abstract available.". In: East Afr Med J. 1982 Jul;59(7):429-34. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Management of chronic pain: practical therapeutics. East Afr Med J. 1982 Jul;59(7):429-34. No abstract available.". In: East Afr Med J. 1982 Jul;59(7):429-34. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

O PROFOBELARTHUR. "Obel AO. Pharmacokinetics in medicine. East Afr Med J. 1982 Nov;59(11):703-4. No abstract available.". In: East Afr Med J. 1982 Nov;59(11):703-4. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Pharmacokinetics in medicine. East Afr Med J. 1982 Nov;59(11):703-4. No abstract available.". In: East Afr Med J. 1982 Nov;59(11):703-4. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

O PROFOBELARTHUR. "Obel AO. Practical therapeutics: advances in antibiotic therapy. East Afr Med J. 1982 Sep;59(9):573-8. No abstract available.". In: East Afr Med J. 1982 Sep;59(9):573-8. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Practical therapeutics: advances in antibiotic therapy. East Afr Med J. 1982 Sep;59(9):573-8. No abstract available.". In: East Afr Med J. 1982 Sep;59(9):573-8. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

O PROFOBELARTHUR. "Obel AO. Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs. East Afr Med J. 1982 Jun;59(6):366-73. Review. No abstract available.". In: East Afr Med J. 1982 Jun;59(6):366-73. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs. East Afr Med J. 1982 Jun;59(6):366-73. Review. No abstract available.". In: East Afr Med J. 1982 Jun;59(6):366-73. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

O PROFOBELARTHUR. "Obel AO. Related Articles, Links Practical therapeutics: the use of insulin. East Afr Med J. 1982 May;59(5):301-5. No abstract available.". In: East Afr Med J. 1982 May;59(5):301-5. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Related Articles, Links Practical therapeutics: the use of insulin. East Afr Med J. 1982 May;59(5):301-5. No abstract available.". In: East Afr Med J. 1982 May;59(5):301-5. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

O PROFOBELARTHUR. "Obel AO. Related Articles, Links Practical therapeutics–use of oral anti-diabetic agents. East Afr Med J. 1982 Feb;59(2):91-5. No abstract available.". In: East Afr Med J. 1982 Feb;59(2):91-5. E Afr Med J; 1982. Abstract
The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.
O PROFOBELARTHUR. "Obel AO. Related Articles, Links Practical therapeutics–use of oral anti-diabetic agents. East Afr Med J. 1982 Feb;59(2):91-5. No abstract available.". In: East Afr Med J. 1982 Feb;59(2):91-5. E Afr Med J; 1982. Abstract

The antihypertensive effect of the fixed combination of timolol, a beta-blocking agent, hydrochlorothiazide, a thiazide diuretic, and amiloride, a potassium sparing agent, was compared against that of methyldopa in an open study lasting 16 weeks in 32 ambulatory African patients with previously untreated diastolic blood pressure of 95-120 mm Hg. A significant fall in mean diastolic and systolic blood pressure was achieved in both groups up to 8 weeks of treatment and was sustained in the timolol-hydrochlorothiazide-amiloride group during the entire follow-up. In the methyldopa group, mean diastolic and systolic blood pressure rose during follow-up. At 16 weeks the fall in mean diastolic and systolic blood pressure was significantly greater in the timolol-hydrochlorothiazide-amiloride treated patients than in the methyldopa group. Adverse reactions were more frequent and severe in the methyldopa group than in timolol-hydrochlorothiazide-amiloride treated patients. It is concluded that the fixed drug combination of timolol-hydrochlorothiazide-amiloride (Moducren) is effective in controlling mild to moderate hypertension in Africans and is better tolerated than methyldopa in these patients. It is further noted that hypertensive patients can be treated with a combination tablet once a day. This is of crucial significance as it would promote better compliance and, hence, minimize the sequelae of poorly controlled hypertension.

S PROFKIGONDUCHRISTINE. "Obwaka J.M., Mati J.K.G., Lequin R.M.,Sekadde-Kigondu C.B., et al J. Obstet. Gynaecol E and Central Africa Afr. 1:96, 1982. Baseline studies in semen and hormonal parameters in normal Kenyan males.". In: et al J. Obstet. Gynaecol E and Central Africa Afr. 1:96, 1982. uon press; 1982. Abstract
PIP: Menstrual blood loss (MBL) was evaluated in 74 nulliporous Kenyan women aged between 20 and 27 years. The hemoglobin levels were all in normal range with the mean of 13.65 +or- 0.8, 13.84 +or- 1.2 and 13.04 +or- 1.2 g/100 ml respectively in 3 populations. The MBL was comparable in the 3 populations with the mean of 35.1 +or- 12.6, 30.6 +or- 8.7 and 32.2 +or- 9.4 ml respectively. There was no difference of statistical significance between the 2 periods studied per each individual. This study objectively assesses the menstrual blood loss in 3 population groups–2 urban and 1 rural. The data can be used to evaluate menstrual blood loss before and after initiation of various contraceptives used in Kenya. Subjects were volunteers who were not on any contraception except barrier or natural rhythm methods, not under psychological stress and who exhibited normal physical female characteristics on examination. Those who wished to drop out, became pregnant or desired contraception, were excluded. The study confirms the individual constancy of the menstrual blood loss in this population. This has important practical implications since a single determination of the menstrual blood loss may be a fairly good expression for the average blood loss in a woman. The immediate effect of various treatments such as IUD insertion or oral contraceptives on the MBL may easily be evaluated quantitatively by measurements in consecutive periods using only 1 period as a control. The quick method can be easily used in evaluating pathological conditions e.g. iron-deficiency due to heavy bleeding, IUD-associated hemorrhage, menorrhagia and uterine fibroid. PMID: 12267056 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Obwaka JM, Mati JK, Lequin RM, Sekadde-kigondu CB, Muitta MN, Nthale JM, Njoroge JK. Baseline studies on semen and hormonal parameters in fertile Black males in Kenya. J Obstet Gynaecol East Cent Africa. 1982 Jun;1(2):96-9.". In: J. Obs/Gyn. East Central Africa 1:126(1982). uon press; 1982. Abstract

PIP: Masturbatory semen specimen from 49 fertile Black African males in Kenya whose wives were pregnant was obtained after at least 3 days of abstinence for the analysis of parameters which included volume motility, vitality, sperm concentration, pH, fructose and acid phosphatase levels. About 1/2 the spermatozoa was actively progressive in motility, while 40% was nonmotile. Vitality in the 1st hour revealed that 81.4% of the sperm was alive. About 90% of the semen specimens had more than 40% idea forms of spermatozoa. Spermatozoal abnormalities were a frequent feature. There was no correlation between age and the testicular volume, but seminal fluid volume and sperm density tended to decrease with age. Serum levels of Follicle Stimulating Hormone, Luteinizing Hormone, Prolactin and Testosterone were determined in the subjects' sera, enabling the establishment of reference values for these parameters in African Kenyan males.

ODUOR PROFOKELLODOMINIC. "ODUOR-OKELO, D. & NEAVES, W.B. (1982). The choriallantoic placenta of the spotted hyena (Crocuta crocuta Erxleben): An electron microscopic study. Anat. Rec.204: 215-222.". In: J. Comp. Biochem. Physiol. 111 C (2): 191-196. Kisipan, M.L.; 1982. Abstract
Adult female Sprague-Dawley rats were injected with corn oil or 5 mg, 20 mg, 25 mg or 30 mg per kg body weight of heptachlor solution every other day for up to 18 days. The rats were killed at the end of the experimental period, and blood samples were assayed for progesterone and oestrogen by radioimmunoassay. Ovarian cells from the rats were isolated and incubated either on their own, or in the presence of LH or FSH, and production of progesterone and oestrogen determined. Control incubations consisted of cells from corn oil-treated rats. The latter were also incubated on their own or in the presence of LH or FSH. Heptachlor significantly suppressed blood progesterone and oestradiol levels (P < 0.05 to P < 0.001), the degree of suppression depending on the dose and the stage of the oestrous cycle in which samples were obtained. Production of oestradiol by ovarian cells from heptachlor-treated rats was lower than for corn oil-treated controls. Cells from rats treated with low doses of heptachlor (5 mg per kg body weight) showed an increased production of progesterone, while high doses (> 20 mg per kg body weight) suppressed production.
ODUOR PROFOKELLODOMINIC. "ODUOR-OKELO, D., & GOMBE, S. (1982). Placentation in the African cane rats (Thryonomys swinderianus) Afric. J. Ecol. 20: 249-266.". In: J. Comp. Biochem. Physiol. 111 C (2): 191-196. Kisipan, M.L.; 1982. Abstract
Adult female Sprague-Dawley rats were injected with corn oil or 5 mg, 20 mg, 25 mg or 30 mg per kg body weight of heptachlor solution every other day for up to 18 days. The rats were killed at the end of the experimental period, and blood samples were assayed for progesterone and oestrogen by radioimmunoassay. Ovarian cells from the rats were isolated and incubated either on their own, or in the presence of LH or FSH, and production of progesterone and oestrogen determined. Control incubations consisted of cells from corn oil-treated rats. The latter were also incubated on their own or in the presence of LH or FSH. Heptachlor significantly suppressed blood progesterone and oestradiol levels (P < 0.05 to P < 0.001), the degree of suppression depending on the dose and the stage of the oestrous cycle in which samples were obtained. Production of oestradiol by ovarian cells from heptachlor-treated rats was lower than for corn oil-treated controls. Cells from rats treated with low doses of heptachlor (5 mg per kg body weight) showed an increased production of progesterone, while high doses (> 20 mg per kg body weight) suppressed production.
OKOTH PROFOKOMBODUNCAN. "OKOMBO (1982) Dholuo Morphophomemic in (a) Generative Framework. Dietrich Reimer Verlag.". In: A book review in Journal of African Languages and Linguistics Vol. 15 - 1, 80-85. CIGR Electocic Journal; 1982. Abstract
isolated from preterm neonates during the outbreak of gastroenteritis in hospital in Nairobi, Kenya, were resistance to trimethoprin-sulfathoxaxole, Chloramphenicol, oxytetracycline and ampicilin, but only a few strains were resistant to cefazolin, cefamandole, cefataximine, amikacin and nalidixic acid. Fourteen different antimicrobial resistance patterns were observed in the 229 strains of E.coli analyzed. Eighty-two percent of the EPEC strains belonged to two resistance patterns. There was no consistent relationship between palsmid profile group and antimicrobial resistance pattern, although one resistance pattern was more frequently observed in EAF-positive strins belonging to the dominant plasmid profile group. Nine percent of the EPEC strins were resistant to gentamicin compared to 37% in the non-EPEC group. No correlation was observed between administration of gentamicin and percentage of resistant strains isolated. None of the nine neonates receiving gentamicin died during the outbreak. Gentamicin resistance was observed in E.coli strains from six out of these nine neonates. Five out of fourteen neonates who received other antimicrobials, or no antibiotic at all, died. Key words: Enteropathogenic Escherichia Coli; antimicrobial resistance;
NDONG&#39;A PROFOMONDILUCIA. "Omondi, L.N. 1982. The Major Syntactic Structures of Dholuo. Supplement 1. Language and Dialect Atlas of Kenya. Diatrich Reimer Verlag, Berlin.". In: Faculty of Education, Kenyatta University. Gitau, W., Ogallo L. A. and Mutemi, J. N.,; 1982.
P PROFONIANG&#39;OCLEMENTM. "Oniang'o, C.M.P. "A Theory of Religion, Ideology and Utopia in Marx".". In: A Journal of Philosophy and Social Action, vol. VIII, No.4 1982 (pp 7-14).; 1982. Abstract
n/a
MUNGE PROFMUKUNYAD. "Onyango, D. and D.M. Mukunya. 1982. Bacterial blight of cassava, Xanthomonas manihotis in Kenya.". In: Proceedings of the Workshop on root and Tuber crops held in Burundi. IITA. Ibadan, Nigeria. Plant Molecular Biology Reporter Vol. 27, pp. 79-85.; 1982. Abstract
The gene Q13L coding for the Capripoxvirus group specific structural protein P32 was expressed in Escherichia coli using plasmid pGEX-2T as a fusion protein with glutathione-s-transferase and purified on glutathione sepharose affinity chromatography column. The protein was then employed for diagnosis of sheeppox, goatpox and lumpyskin disease, by a latex agglutination test (LAT) using the purified P32 antigen and guinea pig detector antiserum raised against the P32 antigen. The LAT and virus neutralization test (VNT) were used to screen one hundred livestock field sera for antibodies to Capripoxvirus, in comparison the LAT was simpler, rapid and 23% more sensitive than the VNT. In addition the LAT was found to be specific for Carpripoxvirus because it did not pick antibodies to Orthopoxvirus and Parapoxvirus. The LA test can be taken for a simple and quick diagnostic tool for primary screening of Carpripoxvirus infection and will reduce the reliance of diagnostic laboratories on tissue culture facilities. Keywords: Carpripox, latex agglutination test, attachment gene J. Trop. Microbiol. Biotechnol. Vol. 3 (2) 2007: pp. 36-43
FREDRICK DRONYANGOJOHN. "Onyango, J.F.: Cleft Lip/Cleft Palate and Oral Facial Defect Management: The need for Oro-facial cleft center in Kenya. Medicom. 1982; 4:.". In: Medicom. 1982; 4:. University of Nairobi Press; 1982. Abstract
This communication presents the first case report of ossifying fibroma of the jaw from Kenya and reviews the literature including the available published case reports from Africa. The relationship between ossifying fibroma and other related benign fibro-osseous lesion of the jaws is briefly discussed. Intensified research work on this condition in Africans is called for so that more cases should be published since it is reportedly more common in black race. The majority of the African cases are generally reported in advanced stages indicating neglect or delay in seeking for medical help. Since ossifying fibroma is a well encapsulated and expansile benign bone neoplasm, surgical enucleation appears to be the treatment of choice; recurrence is rare.
N PROFKANYARIPAULW. "P. W. N. KANYARI (1982). " Goat Trypanosomiasis: Effect of chemotherapy using isometamedium chloride on production in three goat breeds". Kenya Veterinarian 6 (2): 9.". In: Congress of Parasitology (ICOPA), University of Queensland, Brisbane, Australia. August 24th - 29th 1986. Korean Society of Crop Science and Springer; 1982. Abstract
Eimeria christenseni and Eimeria arloingi were used separately to infect one month-old goat kids which were then killed 34 days post-infection. Their small intestines contained small nodular lesions made of several endogenous stages mainly macrogametocytes and macrogametes. Electron microscope studies of macrogametocytes revealed a prominent central nucleus and nucleolus. Other cellular components were mitochondria, wall forming bodies(WFB) type 1( homogenous) and type 2(reticular). Polysaccharide granules of E.christenseni had a chain like arrangement in the young cells, and increased dramatically with maturation of the macrogemetes to become the main cytoplasmic component along with the WFB. Type 1 WFB were peripheral while type 2 were more central but in E.christeseni macrogametes, some type 2 WFB appeared to give rise to membranous vesicles at the areas of wall formation.. The macrogamete nucleus was small and usually indented with polysaccharide granules and reticular bodies, named nuclear derived bodies(NBD), arising from the perinuclear regions. Within the periparasitic areas of both species, membranous/dark bodies were seen. E. arloingi had a large and well defined parasitophorous vacuole(PV), within which an inner lighter, and outer layer with dark granules were found. Both species had some poorly developed intravacuolar tubes(IVT), which occurred at certain points in the case of E.arloingi, while in E.christenseni, they had a diffuse distribution
N PROFKANYARIPAULW. "P. W. N. KANYARI, W. K. MUNYUA, A. J. WILSON, E. W. ALLONBY (1982) "Trypanotolerance and economics among East African goats compared to their crosses with two exotic Breeds". In Karbe, E. and Freitas, E. K. (Eds); pp. 93 - 99.". In: Congress of Parasitology (ICOPA), University of Queensland, Brisbane, Australia. August 24th - 29th 1986. Korean Society of Crop Science and Springer; 1982. Abstract
Eimeria christenseni and Eimeria arloingi were used separately to infect one month-old goat kids which were then killed 34 days post-infection. Their small intestines contained small nodular lesions made of several endogenous stages mainly macrogametocytes and macrogametes. Electron microscope studies of macrogametocytes revealed a prominent central nucleus and nucleolus. Other cellular components were mitochondria, wall forming bodies(WFB) type 1( homogenous) and type 2(reticular). Polysaccharide granules of E.christenseni had a chain like arrangement in the young cells, and increased dramatically with maturation of the macrogemetes to become the main cytoplasmic component along with the WFB. Type 1 WFB were peripheral while type 2 were more central but in E.christeseni macrogametes, some type 2 WFB appeared to give rise to membranous vesicles at the areas of wall formation.. The macrogamete nucleus was small and usually indented with polysaccharide granules and reticular bodies, named nuclear derived bodies(NBD), arising from the perinuclear regions. Within the periparasitic areas of both species, membranous/dark bodies were seen. E. arloingi had a large and well defined parasitophorous vacuole(PV), within which an inner lighter, and outer layer with dark granules were found. Both species had some poorly developed intravacuolar tubes(IVT), which occurred at certain points in the case of E.arloingi, while in E.christenseni, they had a diffuse distribution
N PROFNYAGAP. "P.N. Nyaga, M.M. Kagiko, and J.M. Gathuma. Milk hygiene in nomadic herds in Kenya evaluated by bacterial isolation, bacterial viability trials in traditionally fermenting milk and drug sensitivity. Bull. Anim. Prod. Hlth. Prod. Afric. Vol. 30(1), 1982: 19.". In: Proceedings: 10th Convention, Indian Society for Veterinary Surgery, Nov. 1986. au-ibar; 1982. Abstract

According to the statements made by a number of scholars, in the 80's East African Anglophone novel, which once received a nickname of "social documentary", began to lose gradually its social commitment. Many of the writers known previously as the most active supporters of the social trend, moved their attempts to other literan areas - criminal novel ("Weapon of hunger" by Meja Mцangi, 1989), love story (Yussuf Dawood's "Off my chest", 1988), even children's literature (books for children in Gikuyu, written by Ngugi wa Thiong'o). However, in the late 80's and early 90's East African Anglophone novel stepped onto a new level of social trend, moving from "social documentary" to "social epic". The authors now are trying to sum up the historical experience of East African countries over a large time span, and to that effect appeal mostly to elaborate and spacious literary forms, such as epic novel. These authors, although chosen one and the same literary form, are showing clearly their inclinations towards different styles of writing. For example, Tanzanian author Moyez Vassanji in his novel "The gunny sack" (1989) makes a rather convincing attempt to replant on East African soil the method of "mythological writing", previously used by such author as Gabriel Garcia Marquez. The novel definitely appeals not only to local reader, but to a wider international audience; on its pages the author manages to restore not only the fate of several generations of Indian family, but even the slightest details of their mentality, using myth as one of the basic means for changing the dimensions of time and space, according to the logic of the narration. The development of Kenyan novel in the early 90's confirms also one of the main tendencies in modem literature - bridging between "elite" and popular fiction. The first attempt of an epic novel in Kenyan Anglophone literature was, oddly enough, made by the veteran of Kenyan popular fiction David Maillu in his "Broken drum" H991). The novel hardly aims the widest reading public - nevertheless, stylistically it bears distinct features of popular fiction, such as crime story, romance, etc. Popular novel in East Africa also shows certain inclination towards urgent social themes, but the authors inevitably uses the artistic means they feel most happy with - that is, the style of popular fiction. For example, the "clash of cultures" - the experience of young Africans studying abroad - is presented in the form of a picaresque ("Times beyond" by Omondi Makoloo, 1992) or love story ("The girl from Uganda" by Tengio Urrio, 1993); feministic problems are spiced with sentimentalism ("Judy the nun" by P .Waweru, 1990); the thoughts on the hardships of younger generation are guised in Bildungs roman ("The plight of succession" by a Tanzanian Prosper Rwegoshora, 1990). At the same time, some authors, who have been ploughing successfully the field of pop fiction for a few decades, show their interest in more elaborate literary forms ("Dedan Kimathi: the real story" by Samuel Kaluga, 1990). All the mentioned facts do not allow us to state that the division into popular and elite novel will disappear within the foreseeable future. However, the most interesting developments seem to take place precisely in the field of bridging between these two branches of East African fiction.

O PROFGENGARIEWA. "R. O. Genga Strongly Coupling Effect on Plasma Dispersion in a Magnetic Field; Ph.D. Thesis 1982, Boston College, U.S.A. (Unpublished).". In: International Journal of Theoretical Physics (November 1993 issue. Journal of School of Continuous and Distance Education ; 1982.
G PROFGATEIDAVID. "Rees PH, Gatei DG, de Cock KM, Tosswill J. Some preliminary observations on the investigation of splenomegaly in Kenya. East Afr Med J. 1982 Oct;59(10):658-64. No abstract available.". In: East Afr Med J. 1982 Oct;59(10):658-64. No abstract available. RIVERBRROKS COMMUNICATIONS; 1982. Abstract
Small-intestinal function was studied in 10 patients with visceral leishmaniasis. Vitamin-A absorption was impaired in 7 and d-xylose in 1. In 5 of the 10 patients Leishmania were demonstrated in biopsy specimens of intestinal mucosa. Parasitised macrophages were present in villous tips and less commonly in the lamina propria and submucosa; a moderate inflammatory infiltrate was composed of lymphocytes and plasma cells. 2 patients had partial villous atrophy. There was no correlation between intensity of parasitisation and severity of malabsorption. After treatment with sodium stibogluconate there was a significant improvement in absorption of vitamin A and d-xylose, and biopsy specimens became normal. In 1 patient visceral leishmaniasis was thought to be the cause of chronic diarrhoea.
N PROFGUANTAIA. "Relative distribution of cathinone and D-norpseudoephedrine in Catha edulis (Miraa) growing in Kenya. East Afr Med J. 1982 Jun;59(6):394-8.". In: East Afr Med J. 1982 Jun;59(6):394-8. A. N. GUANTAI, J. W. MWANG1, G1CHURU MURIUKI and K. A. M. KURIA; 1982. Abstract
Cathinone, a potent psychostimulant isolated from young shoots of Catha edulis was given to four human volunteers. Examination of urine collected from the volunteers at predetermined intervals showed the presence of unchanged cathinone, d-norpseudoephedrine, and two unidentified basic substances. The observed biotransformation of cathinone to the less potent psychostimulant, d-norpseudoephedrine involves reduction of a ketone group to alcohol, a common metabolic pathway in humans.
N PROFGUANTAIA. "Relative distribution of cathinone and D-norpseudoephedrine in Catha edulis (Miraa) growing in Kenya. East Afr Med J. 1982 Jun;59(6):394-8.". In: East Afr Med J. 1982 Jun;59(6):394-8. A. N. GUANTAI, J. W. MWANG1, G1CHURU MURIUKI and K. A. M. KURIA; 1982. Abstract
Cathinone, a potent psychostimulant isolated from young shoots of Catha edulis was given to four human volunteers. Examination of urine collected from the volunteers at predetermined intervals showed the presence of unchanged cathinone, d-norpseudoephedrine, and two unidentified basic substances. The observed biotransformation of cathinone to the less potent psychostimulant, d-norpseudoephedrine involves reduction of a ketone group to alcohol, a common metabolic pathway in humans.
P PROFPOKHARIYALGANESH. "Relativistic Significance of Curvature Tensors.". In: Internet. Jour. of Math and Mathematical Sci. (USA), Vol.5, No.1, pp. 133-139. Kenya Journal of Sciences(KJS),; 1982. Abstract
This paper investigates the possibilities of applying emerging management theories and techniques to constitutionally created offices in Kenya and East African region. The benefits from application of these theories, particularly in the judicial services are highlighted.
WANJOHI PROFWARUTADOUGLAS. "Religious Situation in Africa, A paper presented at International Missions Conference, Limuru, Kenya.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1982. Abstract
The Educational Mission of the Church: An African Perspective
SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1981: Activities of the Education and Publications Committee for Geodesy in Africa: 1977 - 1981". A report presented to the Second International Symposium on Geodesy in Africa, Nairobi, November, 1981.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1982.
SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1982: Education in Geodesy at the University of Nairobi. Presented paper at the First International Symposium on Education in Geodesy, Gratz, Austria, September 1982.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1982.
SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1982: Electronics cut errors and legworks. Kenya Engineers, January/February, 1982.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1982.
SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1982: State of Geodetic education in African countries. Presented paper at the First International Symposium on Education in Geodesy, Gratz, Austria, September 1982.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1982.
PROF. KOKWARO JOHNO. "Rutaceae (Orange family) of East African flora, London,.". In: Journal of the East African Natural history Society 75:1-12. University of Nairobi Press; 1982. Abstract
Total number of pages: 515, including 35 pages of colour illustrations.
PROF. KHAMALA CANUTEPM. "Sampling techniques for Populations of Pine Woolly Aphid Pineus pini (Gmelin) (Homoptera).". In: Kenya Sci. & Tech., 3:9-18. Opuscula Mathematica,; 1982. Abstract
n/a
KAUR DRSEHMIJASWANT, KAUR DRSEHMIJASWANT. "Sehmi J.K. et. Al.; Self Sufficiency. M.oH., NPHLS, Nutrition / Food Contaminant Laboratory, Nairobi International Show.". In: M.Sc. thesis, University of Nairobi, Kenya. Canadian Center of Science and Education; 1982. Abstract
Twenty variceal banding sessions were performed in eight patients between February 1995 and September 1996. A total of 69 rings were used to band the varices and at each session between two to six rings were used. Two of the eight had active bleeding and both underwent variceal banding to successfully arrest their bleeding as inpatients. Sixteen other variceal banding sessions were performed on an outpatient basis to obliterate their varices. Four of the eight patients had had sclerotherapy before and varices were still present. No acute or long term complications were noted. In one patient, variceal banding could not be performed as he developed stridor upon placement of the overtube. All the patients had advanced varices (Grade III or IV) and extended for more than 15 cms in the oesophagus. Endoscopic variceal obliteration remains the treatment of choice for patients with portal hypertension with variceal bleeding. Variceal banding is associated with a superior outcome when compared with sclerotherapy; the variceal kill time is shorter, infective complications less, rebleeding occurs less commonly and transfusion requirements are lower.
O PROFBWIBONIMROD, MASIBO PROFWAFULAEZEKIEL. "Serological determination of prevalence of congenital syphilis in two hospitals in Kenya. East Afr Med J . 1982 Nov; 59 ( 11 ): 750-3 . No abstract available. PMID: 6764198 [PubMed - indexed for MEDLINE] Wafula EM, Bwibo NO.". In: East Afr Med J . 1982 Nov; 59 ( 11 ): 750-3 . EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1982. Abstract
No abstract available.
O PROFBWIBONIMROD, MASIBO PROFWAFULAEZEKIEL. "Serological determination of prevalence of congenital syphilis in two hospitals in Kenya. East Afr Med J . 1982 Nov; 59 ( 11 ): 750-3 . No abstract available. PMID: 6764198 [PubMed - indexed for MEDLINE] Wafula EM, Bwibo NO.". In: East Afr Med J . 1982 Nov; 59 ( 11 ): 750-3 . Anim. Hlth. Prod. Afr. 2008; 1982. Abstract

No abstract available.

RUTE DRMARETEGIDEONNTEERE. ""Shocking National Tragedy" a review of Bhabani Bhattacharva's So Many Hungers! In Daily Nation Jan.1982.". In: East African Medical Journal. 68, 526-531. Journal of School of Continuous and Distance Education ; 1982. Abstract
Kamau RK, Osoti AO, Njuguna EM. Department of Obstetrics and Gynaecology, College of Health Sciences, University of Nairobi, P.O. Box 1%76-00202, Nairobi, Kenya. BACKGROUND: Cancer of the uterine cervix is the most common female cancer in Kenya. Despite being preventable, it is often diagnosed when it is already late. For this reason, only palliative therapy is provided. Hence, it is expected that their daily routines and that of their caregivers are severely disrupted. OBJECTIVES: To determine the extent to which diagnosis and treatment of inoperable cervical carcinoma affects quality of life (QOL). DESIGN: Cross-sectional descriptive study. Setting Radiotherapy Department at the Kenyatta National Hospital. SUBJECTS: Women undergoing radiotherapy for inoperable cervical cancer. RESULTS: There is high prevalence of profound disruptions in nearly all domains of QOL. In the social domain, between 33% and 44% had the perception that family members and friends had withdrawn social support. Reduction in various economic facets was reported by 47.4%-52.6%, with 44.7% reporting a fall in the overall living standards. There were significant changes in the sexual domain, as a result in which 28.3% reported marital discordance. In the personality domain, decreased self-esteem and self-projection in life occurred in 30.9% and 36.2% respectively. On functional outcomes (EORTC QLQ-C30), only 32%-41% reported not being affected in the various facets of emotional function. Physical functions were affected in 19%-79%, role functions in 69%-75%; symptoms in 49%-80%; cognitive functions in 46%-56%; social functions in 63%-71% and financial aspects by 63%. On global QOL, 53% and 47% respectively reported high level disruption in overall physical health and overall QOL. CONCLUSION: Severe deterioration of QOL occurs as a result of diagnosis of inoperable cervical cancer and subsequent therapies. For this reason there is need to establish severe disease and end-of-life research and management services that would ensure better coping with cancer for patients and for home-based caregivers. PMID: 17633581 [PubMed - indexed for MEDLINE]
NDEGWA PROFELIJAHNJUGUNA. "Spatial Framework for Regional and National Development. A discussion paper prepared in conjunction with Mr. /. Maleche. Department ol Urban and Regional Planning. 1982.". In: Community Diagnosis and Health Action. A manual for Tropical and Rural areas. Chapter 15. PP130 . African Wildlife Foundation. Nairobi; 1982. Abstract

{ OBJECTIVES To compare sociodemographic profiles, child care, child feeding practices and growth indices of children born to HIV-1 seropositive and seronegative mothers. METHODS: A cohort study of 234 children (seropositive and seronegative) born to HIV-1 seropositive mothers and 139 children born to seronegative mothers in Pumwani Maternity Hospital which serves a low-income population in Nairobi, Kenya from December 1991 and January 1994. RESULTS: With few exceptions, at the time of their birth children in all three cohorts had parents with similar characteristics, lived in similar housing in similar geographical areas, had their mothers as their primary care givers, had similar feeding practices and similar growth status and patterns. However, the HIV-1 seropositive mothers were slightly younger (23.8 years vs. 25.0 years, P < 0.01), if married they were less likely to be their husband's first wife (79% vs. 91%

N. PROFKARANJANANCYK. "Ssali, H. and Mureria, N.K. 1982. Interaction between soil pH, Rhizobium phaseoli strains and bean variety. E. Afric. Agric. and For. J, 45 (1).". In: Poster presented at the 8th Congress of the African Association for Biological Nitrogen Fixation (AABNF), 23-27 November, 1998.; 1982. Abstract
n/a
MWANGI DRMUCHEMIG. "Stevenson, P., Muchemi G. and Karstad, L. 1982 Taenia saginata infection in East African antelopes. Veterinary Record 111:322.". In: East African Agricultural and Forestry Journal. EAMJ; 1982. Abstract
Department of Medical Microbiology, College of Health Sciences, University of Nairobi, Nairobi. Four hundred and thirty six pupils in two primary schools in Kibwezi, Kenya aged between seven and sixteen years and positive for S. mansoni were treated as follows: 320 pupils with a single dose of praziquantel at 40 mg/kg body weight and 116 controls with a placebo. Immediate and delayed side effects of praziquantel were observed. The main side-effects were abdominal pain (36.3%), headache (35.3%) and nausea (13.1%). There was correlation between frequencies of these side-effects and intensity of infection measured as eggs per gram of faeces. Other side-effects included dizziness (9.7%), fever (7.8%), urticaria and bloody diarrhoea. Overall, the side-effects of praziquantel were mild and transient, and did not require any intervention. For ethical reasons, all pupils who served as controls were treated with praziquantel after the study. PMID: 8898462 [PubMed - indexed for MEDLINE]
P PROFPOKHARIYALGANESH. "Study of a new Curvature Tensor in Sasakian Manifold.". In: Tensor (N.S.) Vol.36 ,No.2, pp. 222-26. Kenya Journal of Sciences(KJS),; 1982. Abstract
This paper investigates the possibilities of applying emerging management theories and techniques to constitutionally created offices in Kenya and East African region. The benefits from application of these theories, particularly in the judicial services are highlighted.
P PROFPOKHARIYALGANESH. "Study of a Tensor in Sasakian Manifold.". In: Prog. of Math,Vol.15, pp. 23-27. Kenya Journal of Sciences(KJS),; 1982. Abstract
This paper investigates the possibilities of applying emerging management theories and techniques to constitutionally created offices in Kenya and East African region. The benefits from application of these theories, particularly in the judicial services are highlighted.
OUMA PROFPAMBAHANNINGTON. "Taylor L.G., Okelo G.B.A.and Pamba H.O.:Comparison of Mebendazole (Vermox). Combatrin and Alcopar iln the Treatment of Intestinal Nematodes. Afr. Med. J. 59: 1982.". In: Afr. Med. J. 59: 1982. Opuscula Mathematica,; 1982. Abstract
This paper investigates the possibilities of applying emerging management theories and techniques to constitutionally created offices in Kenya and East African region. The benefits from application of these theories, particularly in the judicial services are highlighted.
OLE PROFMALOIYGEOFFREYM. "TAYLOR, C.R., HEGLUND, N.C. and MALOIY, G.M.O. (1982) Energetics and mechanisms of terrestrial locomotion I. Metabolic energy consumption as a function of speed and body size in birds and mammals. Journal of Experimental Biology 97, 1-21.". In: Proceedings of the 7th Pan-African Ornithological Congress, p. 17. EAMJ; 1982. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
CIARUNJI PROFCHESAINA. "'The Theme of Regeneration in Robert Serumaga's Return to the Shadows' in Africa Thought and Practice Vol. 4 No. 1.". In: Macmillan Kenya. uon press; 1982. Abstract
coming soon at the webstie
S. PROFNTEEREJACOB. "The theory of Achivement Motivation and its Applicability to sport and Physical Education University of Manchester, 1982.". In: University of Manchester, 1989. Institute of African Studies, University of Nairobi; 1982. Abstract
Introduction The Centre for Open and Distance Learning has been established to facilitate the Internal Faculties in launching and managing their programmes using distance mode with a view to increasing access to university education and provide equity in higher education to the learners all over the country. Operational Strategies The operational strategies that have been set up involve collaborative arrangements between the CODL and the Internal Faculties in the development of Study Materials and Learner support Services for off-campus students. The professional in open and distance learning are availed by the Centre to serve the Faculties as trainers while the Faculties provide academic expertise who are facilitated through participatory methods involving application of knowledge, skills and strategies to develop study materials in their respective subjects. Focus The Centre is currently working with Faculties of Science, Commerce and Arts. The Material development process involves training, writing, reviewing and editing followed by conversion to e-content and audio modes. Conclusion These collaborative arrangements will increase access to higher education make significant contribution in the realization of educational Millennium Goals in Kenya where only 20% of all those who qualify obtain admission in the public universities.
P PROFONIANG&#39;OCLEMENTM. "A Theory of Religion, Ideology and Utopia in Marx.". In: A Journal of Philosophy and Social Action, Vol.VIII, No.1982, pp.7-14.; 1982. Abstract
n/a
NGUGI MRTHIMBADAVID. "Thimba D.N and F.M. Itulya, 1982 Rooting of purple passion fruit(Passiflora Edulis Forma edulis Sims)stem cuttings. 11-Influence of Indolebutyric acid (IBA) E.Afr.Agri.For.J.48(1) 5-9.". In: Proceedings of workshop on . RIVERBRROKS COMMUNICATIONS; 1982. Abstract
PMID: 614126 [PubMed - indexed for MEDLINE]
L. PROFWANJALACHRISTOPHER. ""Twilight Years are the Years of Counsel and Wisdom", History and Culture in Western Kenya: The People of Bungoma District through Time, Edited by Simiyu Wandibba [Nairobi G.S. Were Press, 1982] 78 -90.". In: Nyange Publishers.; 1982. Abstract

A random sample survey using personal interviews was conducted in Machakos and Makueni Districts of Kenya in 1992 to estimate the level of rabies vaccination of the dog population. To substantiate the results of the interviews, a sample of the surveyed dogs 3 months old and above were bled for serum rabies antibody determination using an inhibition enzyme immunoassay (INH EIA). Of the 266 surveyed 3 months old and above, only 29% (77/266) were reportedly vaccinated against rabies. Out of the 197 dog sera titrated for rabies antibody, only 29% (57/197) had detectable antibodies and only 16% (32/197) had antibody tires equal to or greater than the threshold considered protective of 0.5 I.U/ml. There was a strong positive association between a history of previous vaccination and the detection of rabies antibodies. Of 133 dogs with no history of previous vaccination, 20% (26/133) had detectable antibodies. With the rabies incidence in Machakos and Makueni Districts still unacceptably high, the level of vaccination estimated in this survey is clearly inadequate for rabies control and measures designed to increase it are discussed.

MUCHAI PROFKAGIKOM, MWANGI PROFGATHUMAJ. "Ushewokunze-Obatolu, U.H.F., Froslie, A., Gathuma, J.M. and Nafsad, I. (1982). Residues of Quintiofos in cattle milk after dermal application of Bacdip. Bull. Anim. Hlth. Prod. Afr. 30 287 .". In: journal. FARA; 1982. Abstract
Experimentally, two hydatid cyst fluid (HCF) antigens (antigens 4 and 5) were found to be the most immunogenic antigens in HCF.  The two antigens were precipitated together from HCF.  This was done by adding 2M phosphotungstic acid and 2M magnesium chloride pollutions to clarified HCF whilte continuously stirring the mixture.  The precipitate formed was suspend in physiological saline (PS).  This antigens solutions was used to coat microtitre plates fro indirect ELISA.  Indirect ELISA was performed on 180 randomly selected bovine sera. The sensitivity of the test was found to be 98% while the specificity was 70%.  The predictive value was 89%.  Although the specificity of the test was relatively low, the test using these partially purified antigens was found to be useful because of its high sensitivity.
MUCHAI PROFKAGIKOM, MWANGI PROFGATHUMAJ. "Ushewokunze-Obatolu, U.H.F., Froslie, A., Gathuma, J.M. and Nafsad, I. (1982). Residues of Quintiofos in cattle milk after dermal application of Bacdip. Bull. Anim. Hlth. Prod. Afr. 30 287 .". In: journal. au-ibar; 1982. Abstract
Antisera to thermostable muscle antigens from 13 wild animals: Buffalo, Waterbuck, Bushbuck, Eland, Oryx, Kongoni, Bushpig, Warthog, Topi, Thomson’s gazelle, Grant’s gazelle, Sheep, Pig, Horse, Camel & Dog, were raised in rabbits and/or goats. Absorptions of the antisera with copolymerized pooled serum from the 20 species and the thermostable muscle antigens rendered most of the antisera mmonospecific. It was possible to identify the species of origin of saline extracts of both cooked and fresh meat samples in immunodiffusion tests. The method is promising for use in identification of the species origin of fresh and cooked animal meats.
KIMANI PROFWAITHAKA. "Waithaka, Kimani and Wanjao, L.W. 1982. The effect of duration of cold treatment on growth and flowering of Liatris. Scientia Horticulturae, 18:153-158.". In: Paper presented at Plant Biotechnology Workshop on . EAMJ; 1982. Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
KIMANI PROFWAITHAKA. "Waithaka, Kimani and Wanjao, L.W. 1982. The influence of corm source, age and size on growth and flowering of Liatris spicata L. Acta Horticulturae, 134:95-100.". In: Paper presented at Plant Biotechnology Workshop on . EAMJ; 1982. Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
C PROFKIPTOONJAPHETH. "Waiyaki P.G., Kiptoon J.C. and Mugera G.M. (1982): Gnidia latifolia (Meisn) toxicity in Rats. The Kenya veterinarian Vol.6 p.10-14.". In: Scientific Conference of Kenya Veterinary Association 21-22 October. 1986. ICASTOR Journal of Engineering; 1982.
KIMANI PROFWAITHAKA. "Wanjao, L.W. and Waithaka, Kimani. 1982. The effect of GA3 application on growth and flowering of Liatris. Scientia Horticulturae, 19: 343-348.". In: Paper presented at Plant Biotechnology Workshop on . EAMJ; 1982. Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
NYAMBURA PROFKIMANIVIOLET. "Why patients go to the traditional healers. Katz SH, Kimani VN.East Afr Med J. 1982 Mar;59(3):170-4.". In: East Afr Med J. 1982 Mar;59(3):170-4. Kireti VM, Atinga JEO; 1982. Abstract

45 Kenyan traditional healers were interviewed with respect to the diagnosis and treatment of eye diseases. Traditional management of eye diseases is based on the healers' concept of the disease causation as well as their knowledge of the herbal, animal and chemical substances that possess (or are reported to possess) remedial effect on the disease. While many of the healers interviewed failed to give a clear distinction between the various eye conditions, diseases such as cataract, foreign bodies and injuries were recognized easily. In almost all cases the medicinal substances were first diluted in water before they were applied to the eyes. Human milk, blood and the white of the egg were the animal substances listed as medicinal to various eye conditions. A solution of sugar was one of the chemical substances used in the treatment of specific eye conditions. Given correct information, some of these healers could f

"Wildlife conservation and decline of pastoralism in Kenya." African Journal of Sociology, vol. II, No. 2, pp. 74 ; 1982. Abstract
n/a
P. PROFMUREITHILEOPOLD. "Writings on the Economy of Kenya in Ole Norgaard Kenya in the Social Sciences An Annoteted Bibliography Nairobi Kenya Literature Bureau.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1982. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
1981
E.N. PN. "Opening speech to Coast Branch N.N.A.K. AGM on team work and nurses welfare.". In: Opening speech to Coast Branch N.N.A.K. AGM on team work and nurses welfare.; 1981. Abstract

Kenya Nurs J. 1981 Jun;10(1):21-2.
Opening speech to Coast Branch N.N.A.K. AGM on team work and nurses welfare.
Ngugi EN.

PMID:
6913629
[PubMed - indexed for MEDLINE]

The following toggler user interface control may not be accessible. Tab to the next button to revert the control to an accessible version.
Destroy user interface controlMeSH Terms

E.N. PN. "Setting the pace: new approaches in nursing practice: paper presented to the International Council of Nurses Congress at the 17th ICN Quadrennial Congress held in Los Angeles in June, 1981.". In: International Council of Nurses Congress at the 17th ICN Quadrennial Congress held in Los Angeles in June, 1981. Los Angeles; 1981. Abstract

Kenya Nurs J. 1981 Dec;10(2):13-5.
Setting the pace: new approaches in nursing practice: paper presented to the International Council of Nurses Congress at the 17th ICN Quadrennial Congress held in Los Angeles in June, 1981.
Ngugi EN.
PMID:
6921385
[PubMed - indexed for MEDLINE]

MOHAMED PROFABDULAZIZ. "A Lexicalist Approach to Bantu Morphology.". In: Annual Conference of the Linguistic Society. Australian National University, Canberra; 1981.
MOHAMED PROFABDULAZIZ. "Language Planning with special reference to East African Countries." University of Washington, Seattle; 1981.
Gichaga FJ. "Industrial Training for Engineering Undergraduates.". In: Engineers Seminar. Nairobi; 1981.
Maitai CK, Talalaj S, Talalaj D, Njoroge D. "Smooth muscle stimulating substances in the stinging nettle tree Obetia pinnatifida." Toxicon. 1981;19(1):186-8.
MOHAMED PROFABDULAZIZ. "1981." The Object Prefix in Bantu. 1981.
"AFFIRMATIVE ACTION AND MINORITY AND WOMEN FACULTY.". In: NAWDAC Annual Convention. San Francisco, California; 1981.
Mutinga MJ, Kaddu, J.B., Irungu LW. "Animal model for feeding Kenyan wild-caught phebotomine sandflies (Diptera: Phlebotomidae)." Insect Sc. Appl. . 1981;2:149-152.
Obel AO, J N, W G. "Antipyrine half - life in hyperthyroidism." East African Medical Journa l . 1981;(58):258-62.
Kokwaro JO. Aquatic resources of Kenya. Mombasa, Kenya; 1981.

UoN Websites Search