PROF. OGENDO HASTINGS W. OKOTH- (DECEASED)
LL.B(E.A),B.LL(OXON),JSD(YALE),FKNAS,FWAAS(KENYA).
Physical Address: KENYA SCHOOL OF LAW P.O. BOX 30197, NAIROBI
254-020-340858,254-020-88494919,0722/518319,/ 0722
Email: okoth@uonbi.ac.ke
Physical Address: KENYA SCHOOL OF LAW P.O. BOX 30197, NAIROBI
254-020-340858,254-020-88494919,0722/518319,/ 0722
Email: okoth@uonbi.ac.ke
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
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