K.O. Abuga, P.M. Mwagiru, G.N. Thoithi, J.M. Nguyo, J .K. Ngugi, O.K. King’ondu, H.N. Mugo and I.O. Kibwage. Quality of Antiretroviral Drugs Analyzed in the Drug Analysis and Research Unit during 2000-2003.

Citation:
"K.O. Abuga, P.M. Mwagiru, G.N. Thoithi, J.M. Nguyo, J .K. Ngugi, O.K. King’ondu, H.N. Mugo and I.O. Kibwage. Quality of Antiretroviral Drugs Analyzed in the Drug Analysis and Research Unit during 2000-2003. ." East Cent. Afr. J. Pharm. Sci.. 2003;6(1):20-23.

Abstract:

Dombeya rotundifolia (Planch) belongs to the Sterculiaceae family and is wide spread in Kenya growing at an altitude of between 900 and 2250m [1]. It is used in traditional medicine in the treatment of rheumatism and diarrhea [2] syphilis [3], heart problems, hemorrhoids, dyspepsia, to regulate the menses and to hasten the onset of labor [4], to manage abdominal pains, intestinal ulceration, headache and haemorrhage, as a tonic and to cause abortion [5-6]
Some general phytochemical and pharmacological studies have been carried out on D. rotundifolia. It has notable anti-bacterial and anti infalammatory activity, and has been found to contain cardiac glycosides, saponins and tannins. It does not contain cyanogenic glycosides and alkaloids [6] the ethanol leaf extract are bacteriostatic against staphylococcus aureus. Ethanol and water extraxt and antibacterial activity against Bacillus subtilis and S. aureus [6-7]. There is no report on previous isolation of compounds from this plant

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