J.A. Orwa, L.K. Keter, S.P.A. Ouko, I.O. Kibwage and G.M. Rukunga. Influence of Manufacturing Practices on Quality of Pharmaceutical products Manufactured in Kenya.

Citation:
"J.A. Orwa, L.K. Keter, S.P.A. Ouko, I.O. Kibwage and G.M. Rukunga. Influence of Manufacturing Practices on Quality of Pharmaceutical products Manufactured in Kenya. ." E.Afr. Med. J. 2004;81(6):287-292.

Abstract:

Dombeya rotundifolia (Planch) belongs to the Sterculiaceae family and is wide spread in Kenya growing at an altitude of between 900 and 2250m [1]. It is used in traditional medicine in the treatment of rheumatism and diarrhea [2] syphilis [3], heart problems, hemorrhoids, dyspepsia, to regulate the menses and to hasten the onset of labor [4], to manage abdominal pains, intestinal ulceration, headache and haemorrhage, as a tonic and to cause abortion [5-6]
Some general phytochemical and pharmacological studies have been carried out on D. rotundifolia. It has notable anti-bacterial and anti infalammatory activity, and has been found to contain cardiac glycosides, saponins and tannins. It does not contain cyanogenic glycosides and alkaloids [6] the ethanol leaf extract are bacteriostatic against staphylococcus aureus. Ethanol and water extraxt and antibacterial activity against Bacillus subtilis and S. aureus [6-7]. There is no report on previous isolation of compounds from this plant

UoN Websites Search