I.O. Kibwage , J. Hoogmartens, E. Roets, H. Vanderhaeghe, L. Ver bist, M. Dubost, C. Pascal, P. Petitjean and G. Levol. Antibacterial activity of erythromycins A,B,C and D and some of their derivatives. J. Antimicrob. Agents Chemother. 28(5) : 630 - 633

Citation:
"I.O. Kibwage , J. Hoogmartens, E. Roets, H. Vanderhaeghe, L. Ver bist, M. Dubost, C. Pascal, P. Petitjean and G. Levol. Antibacterial activity of erythromycins A,B,C and D and some of their derivatives. J. Antimicrob. Agents Chemother. 28(5) : 630 - 633.". 1985.

Abstract:

The MICs of erythromycins A, B, C, and D and some of their derivatives wcrc determined against 21
gram-positive and 15 gram-negative microorganisms. Antibacterial activity was conlined 10 gram-positive and
very few gram-ncgative bacteria. Erythromycin It was somewhat less active than crythromycin A, and
erythromycin C and D showed about half Ihal activity or even less. Most olher derivatives had negligible
activity. Determination of potency by diffusion and turbidimetric assays were in line with MICs. The
cxuminauon of Ihe results of these assays, however, revealed that Ihere are differences between thc data of
dittcrent laboratories, depending on the microorganisms and conditions used,

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