Presentation and initial assessment of laryngeal cancer at Kenyatta National Hospital

Oburra HO. "Presentation and initial assessment of laryngeal cancer at Kenyatta National Hospital.". In: MEDICOM: The African Journal of Hospital and Scientific Medicine, (2010) Vol 25: 33 - 36. MEDICOM; 2010.


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Herbert O. Oburra, Tobias Sholz,  Jochen A. Werner,  Isaac M. Macharia,  Peter Masinde,  Joyce Aswani,  Anselmy Opiyo
MEDICOM The African Journal of Hospital and Scientific Medicine, (2010) Vol  25: 33 - 36
Head and neck cancer occupies over 50% of in-patient beds at the Ear, Nose and Throat-Head and Neck Surgery Unit of the Kenyatta National Hospital. Laryngeal cancer is the third most common head and neck cancer after nasopharyngeal and oral cancers.
Aim: To determine the demographic features, symptomatology, morbid anatomy, histology and disease stage of laryngeal cancer, and to assess the efficiency of the hospital facility in coping with initial work-up and diagnosis of the patients with laryngeal cancer from 1996 to 2001.
Setting: Department of Ear, Nose and Throat/Head and Neck Surgery at The Kenyatta National Hospital
Study design: Retrospective review of case notes of 100 patients admitted to the unit between 1996 and 2001.
Results: Male to female ratio was 24:1. The peak age at presentation was 50 to 70 years with a mean of 60.6 years. Duration of delay between onset of symptoms and presentation to the unit was 4 to 300 weeks with a mean of 50 weeks. Long history of hoarseness of voices and respiratory stridor were the most frequent symptoms. Preoperative tracheostomy rate was 81%. Vocal cords were involved in 54% of cases, 33% supraglottic, 6% subglottic and 7% indeterminate. Delay in obtaining histological results after biopsy ranged from 1 to 71 days with a mean of 43 days. Ninety five per cent of cases had various grades of squamous cell carcinoma. GI differentiation was found in 36%, G2 in 25% and G3 carcinomas involving the vocal cords tended to be well differentiated.




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