Karanja, DN;, Ngatia TA;, Wabacha JK;, Bebora LC.  2008.  The Sensitivity And Specificity Of Clinical Signs, Post-mortem Findings And Isolation Of Escherichia Coli In Diagnosing Edema Disease Of Swine.. Abstract

Commonly used diagnost ic techniques for edema disease in Kenya were tested for their sensitivity and specificity on 84 pig carcasses submitted to Department of Veterinary Pathology and Microbiology between June 2004 and June 2007. Clinical signs gathered from anamnesis, post - mortem lesions revealed at autopsy and E. coli isolated from intestinal contents and characterized using biochemical tests and polymerase chain reacti on were compared using receiver - operating characteristic analyses. A combination of clinical signs, post - mortem findings and isolation of E. coli carrying F18 and shiga - toxin type II variant genes were used as gold standard test. Forty nine (58.3%) cases w ere diagnosed as edema disease, based on clinical signs and post - mortem findings . Of these, thirty eight (77.6%) had variable amounts of edema in various body si tes and clinically, twenty six (53.1%) had neurological signs, 18 (36.7%) were found dead, 3 ( 6.1%) had swollen eyelids and 2 (4.1%) expressed respiratory distress. Hemolytic E. coli carrying the tested genes were isolated from thirty one (62.2%) of these cases. Presence of edema in various body cavities and observation of defined clinical signs h ad 75.3% and 57.4% sensitivity, respectively. Considered individually, the sensitivity was 64.7% for found dead, 50% for neurological signs and 84.4% for isolating hemolytic E. coli. All had a specificity of 81.3%. The results show that none of the diagnos tic techniques had the expected 100% sensitivity and specificity, but isolation of hemolytic E. coli may be an important screening test for suspected edema disease cases


Abuom, TO;, Mogoa EG;, Gitonga P;, Ngatia TA;, Maingi AN.  2006.  Sebaceous Gland Adenocarcinoma In A Cow..
Gichohi, CM;, Mbuthia PG;, Waruiru RM;, Ngatia TA;, Maingi EM;, Weda EH;, Otieno R.  2006.  Preliminary study on the occurrence of endoparasites and their associated pathological lesions in four fish species.


Kanyari, PWN;, Ngatia TA;, Mathiu PM;, Oyejide A;, Srivastava KK.  2005.  Some Causes of Poor performance and chick mortality in farmed ostriches in Alabama[USA] and Kenya.


Maina, AN;, Mbuthia PG;, Ngatia TA;, Waruiru R;, Bebora LC.  2004.  Staphylococcus aureus, Listeria species and parasitic lungworm infection in marketed indidenous chickens.
  2004.  Characterisation of Theileria parva isolates from Kiambu district, Kenya.. Veterinary Parasitolology. 121(3):247-53.


Karanja, DN;, Ngatia TA;, Gathumbi JK.  2002.  Edema Disease Of Swine: A Major Disease Problem In Kenya. ..



Kabuage, LW;, Mbugua PN;, Mitaru BN;, Ngatia TA.  1998.  Utilisation Of Minerals In Grain Amaranth Diets By Broiler Chickens.


Ngatia, TA;, Mbuthia PG;, Waruiru RM;, Njiro SM;, Kanyari PWN;, Munyua W k;, Weda EH;, Ngotho J.  1997.  Parasites And Microscopic Lesions In The Livers Of Slaughtered Wild Animals In Kenya"..


Kabuage, LW;, Mbugua PN;, Mitaru BN;, Ngatia TA.  1996.  Effect Of Amino Acid Supplementation Of Raw And Thermal Processed Amaranth Diets On Broiler.


Karanja., DN;, Ngatia TA;, Wandera JG.  1994.  The Role of Donkeys in Trypanosoma congolense infections..


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