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WANYOIKE DRGICHUHIJOSEPH, K. PROFSINEISAMUEL, OTIENO DRODAWAFRANCISXAVIER. "Cohen R, Joseph Gichuhi, Rukaria R, Sinei SK, Gultai S.Investigation of immunogenetic correlates for Chlamydia trachomatis associated tubal infertility. American Journal of Obstetric and Gynaecology Vol 101 .". In: American Journal of Obstetric and Gynaecology Vol 101 . Central artificial Insemination Station Magazine; 2003. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
Wanyoike MW. "Technology and Provision of Quality and Inclusive Education.". In: International Conference on “Uplifting the Poor”, Linkoping University and University of Nairobi February 15th -16th 2013. University of Nairobi; 2013.
WANYOIKE DRGICHUHIJOSEPH, K. PROFSINEISAMUEL, OTIENO DRODAWAFRANCISXAVIER. "Cohen R, Joseph Gichuhi, Rukaria R, Sinei SK, Gultai S.Investigation of immunogenetic correlates for Chlamydia trachomatis associated tubal infertility. American Journal of Obstetric and Gynaecology Vol 101 .". In: American Journal of Obstetric and Gynaecology Vol 101 . Starmat Designers & Allied, Nairobi; 2003. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Reproductive Health: Abortion, Pregnancy, Fertility, Contraception A chapter in: Forensic medicine, Medical Law and Ethics in East Africa (2005). Contribution from: J. Wanyoike Gichuhi, Peter Kimani, Editors: Mahomed A. Dada, Kirasi A. Olumbe, David J. Mc.". In: Journal of Obstetrics and Gynaecology of East Africa. Vol. 18 No. 1:1-66 May 2005. Starmat Designers & Allied, Nairobi; 2005. Abstract
{ OBJECTIVE: To examine the effect of human immunodeficiency virus (HIV)-1 infection on treatment outcome of laparoscopically verified acute salpingitis. METHODS: Women aged 18-40 years with laparoscopically verified acute salpingitis received antibiotic therapy that included cefotetan 2 g intravenously and doxycycline 100 mg orally every 12 hours and laparoscopically guided drainage of tuboovarian abscesses of 4 cm or more. Clinical investigators blinded to HIV-1 serostatus used predetermined clinical criteria, including calculation of a clinical severity score and a standard treatment protocol to assess response to therapy. RESULTS: Of the 140 women with laparoscopically confirmed acute salpingitis, 61 (44%) women had mild, 38 (27%) had moderate, and 41 (29%) had severe disease (ie, pyosalpinx, tuboovarian abscesses, or both). Fifty-three (38%) were HIV-1-infected. Severe disease was more common in HIV-1-infected in comparison with HIV-1-uninfected women (20 [38%] compared with 21 [24%]
WANYOIKE DRGICHUHIJOSEPH, WANYOIKE DRGICHUHIJOSEPH. "Mugo NR, Kiehlbauch JA, Nguti R, Meier A, Gichuhi JW, Stamm WE, Cohen CR. Department of Obstetrics and Gynecology, Kenyatta National Hospital, Nairobi, Kenya. Effect of human immunodeficiency virus-1 infection on treatment outcome of acute salpingitis.Obs.". In: PMID: 16582116 [PubMed - indexed for MEDLINE]. Starmat Designers & Allied, Nairobi; 2006. Abstract
{ OBJECTIVE: To examine the effect of human immunodeficiency virus (HIV)-1 infection on treatment outcome of laparoscopically verified acute salpingitis. METHODS: Women aged 18-40 years with laparoscopically verified acute salpingitis received antibiotic therapy that included cefotetan 2 g intravenously and doxycycline 100 mg orally every 12 hours and laparoscopically guided drainage of tuboovarian abscesses of 4 cm or more. Clinical investigators blinded to HIV-1 serostatus used predetermined clinical criteria, including calculation of a clinical severity score and a standard treatment protocol to assess response to therapy. RESULTS: Of the 140 women with laparoscopically confirmed acute salpingitis, 61 (44%) women had mild, 38 (27%) had moderate, and 41 (29%) had severe disease (ie, pyosalpinx, tuboovarian abscesses, or both). Fifty-three (38%) were HIV-1-infected. Severe disease was more common in HIV-1-infected in comparison with HIV-1-uninfected women (20 [38%] compared with 21 [24%]
Wanyoike MW. "Educational Reforms and Value-creating education in post-colonial Kenya: A Historical perspective.". In: International Conference on Value-Creating Education and Sustainable Development. University of Nairobi; 2016.
WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Amniotic fluid embolism: case report and review. Wanyoike J G Journal of Obstetrics and Gynaecology of Eastern and central Africa. Vol 18 NO 1:1-66 May 2005.". In: Journal of Obstetrics and Gynaecology of Eastern and central Africa. Vol 18 NO 1:1-66 May 2005. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 2005. Abstract
Effects of calcium supplementation in patient at risk of pregnancy induced Hypertension. (This was an experimental double blind randomized clinical trial.) J. Obset. Gynaecol. East Cent.Afr 2005, 18:49-59
WANYOIKE DRGICHUHIJOSEPH. "Incidence of wound infection after caesarean delivery in a district hospital in central Kenya. East Afr Med J. 2005 Jul;82(7):357-61.". In: East Afr Med J. 2005 Jul;82(7):357-61. Starmat Designers & Allied, Nairobi; 2005. Abstract
OBJECTIVE: To determine the incidence of post-caesarean wound infection. DESIGN: Prospective descriptive study. SETTING: Maternity unit of Kiambu District Hospital in Central Province of Kenya. SUBJECTS: All women undergoing caesarean delivery during the study period. MAIN OUTCOME MEASURES: Overall incidence of post-caesarean wound infection, relationship between incidence and socio-demographic characteristics, pre-operative labour events, intrapartum events as well as HIV status. RESULTS: The caesarean delivery rate was 7.8%. The overall post-caesarean wound infection rate was 19%. The incidence was 32% among single women as compared to 16% among married women, but this difference is not statistically significant. Among the 35% of women who laboured for more than 12 hours, the incidence of wound infection was 33% compared to 15% among those who laboured for 12 hours or less (p < 0.01). Rupture of membranes (ROM) for more than 12 hours was associated with high incidence of wound infection than among women in whom ROM was 12 hours or less (38% and 14% respectively, p < 0.001). Also duration of operation exceeding 60 minutes was associated with much higher incidence of wound infection (71%) compared to when the operation lasted 60 minutes or less (16%, p < 0.001). The incidence of post-caesarean wound infection does not appear to be significantly affected by HIV status or whether caesarean delivery was emergency or elective. CONCLUSION: The overall post-caesarean wound infection rate is quite high. Prolonged pre-operative duration of labour, prolonged ROM and long duration of operation are associated with significantly higher incidence of wound infection. This should be seen against a background of a relatively low caesarean delivery rate and high incidence of prolonged labour. Strict labour management policies need to be inculcated in labour wards in District Hospitals in order to ensure timely caesarean delivery interventions, and hence, reduce post-caesarean wound infection rates.
Wanyoike, MM; Wahome RG. "Small-scale farming systems."; 2004.
Wanyoike M, Holmes W. "The effects of winter nutrition on the subsequent Jive-we ght performance and intake of herbage by beef cattle.". 1981. Abstract

Thirty-six Friesian and Friesian cross-bred cattle about 11 months old were fed to grow at the rates of 0·50 (low) and 1·08 (high) kg/day in a 12-week winter feeding period and then turned out on high quality pasture. For 12 weeks after turning out the ‘low’ and ‘high’ animals gained weight at 1·17 and 0·90 kg/day respectively. There was a negative correlation (– 0·57, P < 0·01) between winter and grazing live-weight gain. On two occasions herbage intake was estimated. Average intake of ‘low’ animals was 12% higher than of ‘high’ animals although herbage digestibility, estimated from faecal N, was similar for the two treatments. Differences in live-weight gain on pasture between treatments were largely accounted for by differences in intake. The low rate of winter growth did not have any significant effects on age at slaughter, carcass weights or grades attained by the restricted animals.

WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Amniotic fluid embolism: case report and review. Wanyoike J G Journal of Obstetrics and Gynaecology of Eastern and central Africa. Vol 18 NO 1:1-66 May 2005.". In: Journal of Obstetrics and Gynaecology of Eastern and central Africa. Vol 18 NO 1:1-66 May 2005. Starmat Designers & Allied, Nairobi; 2005. Abstract
{ OBJECTIVE: To examine the effect of human immunodeficiency virus (HIV)-1 infection on treatment outcome of laparoscopically verified acute salpingitis. METHODS: Women aged 18-40 years with laparoscopically verified acute salpingitis received antibiotic therapy that included cefotetan 2 g intravenously and doxycycline 100 mg orally every 12 hours and laparoscopically guided drainage of tuboovarian abscesses of 4 cm or more. Clinical investigators blinded to HIV-1 serostatus used predetermined clinical criteria, including calculation of a clinical severity score and a standard treatment protocol to assess response to therapy. RESULTS: Of the 140 women with laparoscopically confirmed acute salpingitis, 61 (44%) women had mild, 38 (27%) had moderate, and 41 (29%) had severe disease (ie, pyosalpinx, tuboovarian abscesses, or both). Fifty-three (38%) were HIV-1-infected. Severe disease was more common in HIV-1-infected in comparison with HIV-1-uninfected women (20 [38%] compared with 21 [24%]
Wanyoike AN, Oleche OM. "Determinants of Utilization of Health Care Services in Kenya." International Journal of Academic Research in Business and Social Sciences. 2017;7(10).
WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Gachuno O W, Wanyoike Gichuhi J, Rukaria R M K Effects of calcium supplementation in patients at risk of pregnancy induced hypertension Journal of Obstetrics and Gynaecology of East Africa. Vol. 18 No. 1:1-66 May 2005. Gachuno O W, Wanyoike Gichuhi J, Ruk.". In: Journal of Obstetrics and Gynaecology of East Africa. Vol. 18 No. 1:1-66 May 2005. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 2005. Abstract
Effects of calcium supplementation in patient at risk of pregnancy induced Hypertension. (This was an experimental double blind randomized clinical trial.) J. Obset. Gynaecol. East Cent.Afr 2005, 18:49-59
Wanyoike, MM; Wahome RG; MSG, Wahome, RG; Mbogoh SG, Wahome, RG; Mbogoh SG. "Issues Constraining Production, Processing and Marketing of Dairy and Other Livestock Products."; 2005.
Wanyoike G, Rukaria RK, Gachuno OW. "Risk factors associated with tubal infertility.". 2009.
WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Wanyoike J G. A case of reproductive technology in Africa: Wanyoike J G. Journal of Obstetrics and Gynaecology of Eastern and central Africa. Volume 17 No 1:1-80 February 2004.". In: Journal of Obstetrics and Gynaecology of Eastern and central Africa. Volume 17 No 1:1-80 February 2004. Starmat Designers & Allied, Nairobi; 2004. Abstract
OBJECTIVE: To determine the incidence of post-caesarean wound infection. DESIGN: Prospective descriptive study. SETTING: Maternity unit of Kiambu District Hospital in Central Province of Kenya. SUBJECTS: All women undergoing caesarean delivery during the study period. MAIN OUTCOME MEASURES: Overall incidence of post-caesarean wound infection, relationship between incidence and socio-demographic characteristics, pre-operative labour events, intrapartum events as well as HIV status. RESULTS: The caesarean delivery rate was 7.8%. The overall post-caesarean wound infection rate was 19%. The incidence was 32% among single women as compared to 16% among married women, but this difference is not statistically significant. Among the 35% of women who laboured for more than 12 hours, the incidence of wound infection was 33% compared to 15% among those who laboured for 12 hours or less (p < 0.01). Rupture of membranes (ROM) for more than 12 hours was associated with high incidence of wound infection than among women in whom ROM was 12 hours or less (38% and 14% respectively, p < 0.001). Also duration of operation exceeding 60 minutes was associated with much higher incidence of wound infection (71%) compared to when the operation lasted 60 minutes or less (16%, p < 0.001). The incidence of post-caesarean wound infection does not appear to be significantly affected by HIV status or whether caesarean delivery was emergency or elective. CONCLUSION: The overall post-caesarean wound infection rate is quite high. Prolonged pre-operative duration of labour, prolonged ROM and long duration of operation are associated with significantly higher incidence of wound infection. This should be seen against a background of a relatively low caesarean delivery rate and high incidence of prolonged labour. Strict labour management policies need to be inculcated in labour wards in District Hospitals in order to ensure timely caesarean delivery interventions, and hence, reduce post-caesarean wound infection rates.
Wanyoike MM;, Wahome RG. "Small-scale farming systems."; 2004.
WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Wanyoike J G. A case of reproductive technology in Africa: Wanyoike J G. Journal of Obstetrics and Gynaecology of Eastern and central Africa. Volume 17 No 1:1-80 February 2004.". In: Journal of Obstetrics and Gynaecology of Eastern and central Africa. Volume 17 No 1:1-80 February 2004. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 2004. Abstract
Effects of calcium supplementation in patient at risk of pregnancy induced Hypertension. (This was an experimental double blind randomized clinical trial.) J. Obset. Gynaecol. East Cent.Afr 2005, 18:49-59
WANYOIKE DRGICHUHIJOSEPH, OTIENO DRODAWAFRANCISXAVIER. "Gachuno O W, Wanyoike Gichuhi J, Rukaria R M K Effects of calcium supplementation in patients at risk of pregnancy induced hypertension Journal of Obstetrics and Gynaecology of East Africa. Vol. 18 No. 1:1-66 May 2005. Gachuno O W, Wanyoike Gichuhi J, Ruk.". In: Journal of Obstetrics and Gynaecology of East Africa. Vol. 18 No. 1:1-66 May 2005. Starmat Designers & Allied, Nairobi; 2005. Abstract
{ OBJECTIVE: To examine the effect of human immunodeficiency virus (HIV)-1 infection on treatment outcome of laparoscopically verified acute salpingitis. METHODS: Women aged 18-40 years with laparoscopically verified acute salpingitis received antibiotic therapy that included cefotetan 2 g intravenously and doxycycline 100 mg orally every 12 hours and laparoscopically guided drainage of tuboovarian abscesses of 4 cm or more. Clinical investigators blinded to HIV-1 serostatus used predetermined clinical criteria, including calculation of a clinical severity score and a standard treatment protocol to assess response to therapy. RESULTS: Of the 140 women with laparoscopically confirmed acute salpingitis, 61 (44%) women had mild, 38 (27%) had moderate, and 41 (29%) had severe disease (ie, pyosalpinx, tuboovarian abscesses, or both). Fifty-three (38%) were HIV-1-infected. Severe disease was more common in HIV-1-infected in comparison with HIV-1-uninfected women (20 [38%] compared with 21 [24%]
Wanyoike AN, Oleche OM. "Determinants of Demand for Healthcare Services in Private Hospitals in Kenya." International Journal of Novel Research in Marketing Management and Economics . 2017;4(3):9-30.
WanyanguSamuel, AngolioA, MachariaS, LitamoiJK, OdongoMahacla. "A preliminary serological survey for leptospiral agglutinins in sheep and goats in Kenya." The East African Agricultural and Forestry Journal. 1990;56 (1):15-19.
Wanyande, Peter; Omosa M; CL. "Governance and Transition Politics in Kenya .". 2007.Website
Wanyande P. "Reflections on Electoral Systeme and Practice in Kenya in Hekima ." A Journal of Humanities and Social Sciences. 2003;Volume 11(May-JULY 2003-1):PP23-25.
Wanyande P, Odhiambo-Mbai C. Public Service Ethics in Kenya.; 2001.Website
Wanyande P. "Nationalism In Kenya: Weakening the Ties that Bind." Maseno University Journal. 2012;volume 1:pp207-219.
Wanyande P, and Asingo PO. "Beyond Election Campaign Rhetoric: Challenges Facing NARC Government in Kenya." African Review Journal . 2004;31 ( 1&2 ):38-56.
Wanyande P. "Refugees and Internally Displaced Persons: A Governance Perspective. In Regional Development Studies." A journal of the United Nations Centre for Regional Development. 2006:pp145-160.
Wanyande P, Njeru G, Mute L, Owiti MOD. Civic Education for Marginalised Communities.; 2001.
Wanyande P, Omosa M, Ludeki C. Governance Issues in Kenya: An Overview.; 2007.Website
Wanyama J, Mpoke L, Mbaria JM, Kaburia HFA, Gathuma JM. "Participatory validation of medicinal plants used to treat livestock diseases by pastoralists of Kenya: A case of Samburu and Turkana pastoralists.". In: Proceedings of the First National Workshop on medicinal, aromatic and other underutilized plant species in Kenya. Kenya Wildlife Service Training Institute, Naivasha, Kenya; 2001.
Wanyama HN, Karega LN, Chimoita EL. "Effect of Use of Tacit Knowledge Transfer Techniques on Organizational Performance of Kenya Agricultural and Livestock Research Organization Researchers." Journal of Agricultural Extension, Economics &Sociology. 2022;0(10)(0(10): 492-502):DOI: 10.9734/AJAEES/2022/v40i1031103.effectof_use_of_tacit_knowledgetransfer_techniques.pdf
WANJOHI PROFWARUTADOUGLAS. "Religion as a Source of Oppresion or Resistance, in S. Maimela, Ed., Culture, Religion and Liberation, Pretoria, S.A.: UNISA.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1994. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Scratching where it itches: Developing Christian Literature in Africa, a paper presented at a Conference on the production of Christian Education materials in Africa, Limuru, Kenya.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1983. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Pastoral Counselling in the African Perspective, in D. W. Waruta, Ed., Caring and Sharing: Pastoral Counselling in the African Perspective, Nairobi: Uzima Press.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1995. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "The Church as a Teaching Community in J.N.K. Mugambi, Ed. Christian Mission and Social Transformation, Nairobi, Initiatives & NCCK.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1989. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "A Gospel of Community, Compassion and Continuity in Daniel Carro and Richard E. Wilson, Contemporary Gospel Accents: Coing Theology in Africa, Asia, and Latin America, Macon, Georgia: Mercer University Press.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1997. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "Oriental Religions in J.N.K. Mugambi, Ed. Comparative Religion, Nairobi, University of Nairobi Press.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Who Is Jesus in Africa? Priest, Prophet and King in J.N.K.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1998. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "Oriental Religions in J.N.K.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
Wanjohi M, Gitao CG, Bebora L. "Subclinical mastitis affecting hygienic quality of marketed camel milk from North - Eastern Province, Kenya." Microbiology Research International. 2013;1(1):6-15. Abstract13-012.pdf

North Eastern Province, camel is the dominant livestock; it provides subsistence to many people especially during the frequent droughts when other animals either die or are unthrifty. This is beca use camel is highly suited for hot environments. In this region, camels number approximately 3 million and are the main producers of milk for the residents, who are mainly of Somali origin, and are pastoralists. Currentl y, the milk is also sold in Nairobi and other far places; and there is a fast growing demand for it. This has necessitated examination of the milk quality, in response to food safety awareness, especially noting that some of the bacteria causing subclinical mastitis can cause disease in humans. This study was carried out to establish the hygienic quality of camel milk from this area, zeroing down to 2 districts, Garissa and Wajir. T hree hundred and eighty four bulk camel milk samples were collected in volumes of 200 to 300 ml. They wer e transport ed to the laboratory in cold/ice boxes and bacterial isolation and characterization done not later than 24 h after arrival at the laboratory. Before culturing, the milk samples were screened using Ca lifornia Mastitis Test (CMT); samples testing positive (a n indication of subclinical mastitis) were then subjected to bacteriological investigation, using standard methods. Results of this study have shown that subclin ical mastitis is prevalent in dromedary camels of Garissa and Wajir districts of North Eastern province of Kenya, and that Gram positive cocci ( Staphylococcus and Streptococcus) are the dominant mastitis pathogens isolated. Other isolated bacteria included Klebsiella/Enterobacter, E scherichia coli and Bacillus. The positive correlation of CMT with the presen ce of mastitis pathogens in camel milk showed that CMT is a useful screening test in the detection of subclinical mastitis in camels; it is thus a useful tool for farm ers, aiding them in picking the affected animals, segregating and treating them. The resu lts also contribute towards coming up with respective control measures so as to keep camel milk fresh for longer periods and als o make it safe for human consumption.

WANJOHI PROFWARUTADOUGLAS. "Marriage and Family in Africa, in D. W. Waruta and H.W. Kinoti, Eds., Pastoral Care in African Christianity: Challenging Essays in Pastoral Theology, Nairobi: Uzima Press.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 2001. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "Tribalism as a Moral Problem in Contemporary African Society, in J.N.K. Mugambi and A. Nasimiyu Wasike, Eds. Moral and Ethical Issues in African Christianity: Innovative Essays in Moral Theology, Nairobi: Uzima Press.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1992. Abstract
The Educational Mission of the Church: An African Perspective
Wanjohi LM, Moturi CA. "Smartphones Supporting Monitoring Functions: Experiences from Sweet Potato Vine Distribution in sub-Saharan Africa.". In: Digital Technologies for Agricultural and Rural Development in the Global South. Oxfordshire: CAB International; 2018.
WANJOHI PROFWARUTADOUGLAS. "Meaning of Mission in Africa Today; Nairobi.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1994. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Religious Situation in Africa, A paper presented at International Missions Conference, Limuru, Kenya.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1982. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Marriage and Family in Africa.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1994. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Ecumenical Initiatives in Eastern Africa: The Current Situation.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1989. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Biblical Hermeneutics in the African Instituted Churches in H.W. Kinoti and J.M. Waligo, Eds., Nairobi, Uzima Press.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1997. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "Marriage and the Changing Values in the African Family.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Bible and Prayer in Africa in The International Bible Commentary: A Catholic and Ecumenical Commentary for the 21st Century, William R. Farmer, General Editor, Collegeville, Minnesota, USA: Liturgical Press.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1998. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "The Recovery of African Spirituality, A paper presented at the Regional Conference of Ecumenical Association of Third World Theologians (EATWOT), Nairobi.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "The Educational Mission of the Church: An African Perspective, in A. Nasimiyu Wasike and D. W. Waruta, Eds., Mission in African Christianity: Critical Essays in Missiology, Nairobi: Uzima Press.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 2000. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "The Effect of the Debt Crisis on the Family in Africa.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1991. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "The Educational Mission of the Church: An African Perspective.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1993. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Cast Away Fear, A Joint Contribution to the African Synod, Nairobi: ew People.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1994. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "S. G. Kibicho and D. W. Waruta, African 'Religion in BRP 201 and 202 Lecture Series.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1989. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Pastoral Counselling in the African Perspective.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1995. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Biblical Authority and Interpretation.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Who Is Jesus in Africa: Priest, Prophet and King in J.N.K. Mugambi and L. Magesa, Eds., Jesus in African Christianity: Experimentation and Diversity in African Christology, Nairobi Initiatives.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1998. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "owards an African Church: A Critical Assessment of Alternative Forms and Structures in J.N.K. Mugambi and L. Magesa, Eds. The Church in African Christianity: Innovative Essays in Ecclesiology, Nairobi: Initiatives.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
WANJOHI PROFWARUTADOUGLAS. "Social-Historical Structures of Racism in Denton Lotz, Ed., Baptists Against Racism, McLean, Birginia, USA: Baptist World Allicance.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 1999. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "Towards an African Church: A Critical Assessment of Alternative Forms and Structures.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1990. Abstract
The Educational Mission of the Church: An African Perspective
Wanjohi M, Gitao CG, Bebora L. "The Prevalence of Brucella spp. in camel milk marketed from North Eastern Province, Kenya." Research Opinions in Animal & Veterinary Sciences. 2012;2(7):425-434. Abstractcamel_milk_brucellosis.pdf

The camel is the dominant livestock in North Eastern province where it provides sustenance to many people especially during the frequent dry periods when other animals die or are unthrifty. Garissa and Wajir districts in the arid Northern Kenya hosts about 54% of the national camel herd estimated to number over 3 million. Camel milk from North Eastern Province in Kenya is widely marketed in those areas but is also currently being sold in distant markets in Nairobi and other places. An expanded camel milk market provides an opportunity for increased income that can lead to improved pastoral livelihoods. Most of the milk is collected from individual pastoralists, bulked and then taken by transporters to urban areas. While some milk is boiled before sale, some of the milk however is marketed as raw thus exposing the population to zoonotic diseases. In an investigation to find the prevalence of Brucellosis, the main zoonotic agent in milk, samples of milk for marketing were collected as well as serum samples from camels in North Eastern Province A total of three hundred and eighty four (384) camel milk samples from Garrissa and Wajir Districts were tested using the Milk Ring Test (MRT) and out of the total, fifty nine (59) samples (15.36%) tested positive while three hundred and twenty five (325) samples tested negative. From Garrissa District (n = 230), 35 samples (15.22%) were positive for MRT while 24 samples (15.58%) from Wajir District (n = 154) were positive. All the milk samples examined were negative for Brucella Modified Ziehl- Neelsen’s stain as well as primary isolation of Brucella on Tryptose Soy agar (TSA) under high carbon-dioxide (CO2) concentration. The results of the milk ring test on the samples tested indicated that 15.36% of the samples were positive for the presence of Brucella antibodies in milk. A total of two hundred (200) camel serum samples from Garrissa and Wajir Districts were tested using the Rose Bengal Plate Test (RBPT). Four (4) samples (2.0%) tested positive. From Garrissa District (n = 72), 2 samples (2.78%), were positive while 2 samples (1.56%) from Wajir District (n = 128) were positive. The two hundred (200) camel serum samples from Garrissa and Wajir Districts were also tested using the Serum Micro-agglutination Test (SAT). From Garrissa District (n = 72), 13 samples (18.06%) were positive while 8 samples (6.25%) from Wajir District (n = 128) were positive. The seroprevalence of brucellosis in camels is low in extensively kept pastoralist camels. Some of the recommendations to avoid the risk of zoonotic diseases include increased awareness on pasteurization of camel milk, proper milk handling and milk testing before pooling

WANJOHI PROFWARUTADOUGLAS. "Co-Editor:Africa Challenge.". In: All Africa Journal of Theology, Sponsored by the All Africa Conference of Churches (AACC) and Conference of African Theological Institutions (CATI), Vol. 1. Starmat Designers & Allied, Nairobi; 2001. Abstract
Cohen CR, Gichui J, Rukaria R, Sinei SS, Gaur LK, Brunham RC. Departments of Obstetrics and Gynecology, University of Washington, Box 356460, Seattle, WA 98195, USA. crcohen@u.washington.edu OBJECTIVE: To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS: We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082, -819, and -592 promoters; interleukin 6-174 promoter; and interferon gamma+874 codon 1) among Kenyan women with confirmed tubal infertility with and without C trachomatis microimmunofluorescence antibody. RESULTS: Two class II alleles, HLA-DR1*1503 and DRB5*0101, were detected less commonly in C trachomatis microimmunofluorescence seropositive women than in C trachomatis microimmunofluorescence seronegative women with infertility (0% versus 20%; odds ratio [OR] 0.05; 95% confidence interval [CI] 0, 0.7, and 6% versus 26%; OR 0.2; 95% CI 0.02, 1.0, respectively). These alleles are commonly linked as a haplotype at the DRB locus. This finding could not be explained through linkage disequilibrium with the other studied HLA or cytokine genes. CONCLUSION: These alleles may lead to an immunologically mediated mechanism of protection against C trachomatis infection and associated tubal damage, or alternatively increase risk for tubal scarring due to another cause. PMID: 12636945 [PubMed - indexed for MEDLINE]
WANJOHI PROFWARUTADOUGLAS. "Religious Tolerance in a Pluralistic World.". In: Tangaza Occassional Papers, No. 1. Starmat Designers & Allied, Nairobi; 1992. Abstract
The Educational Mission of the Church: An African Perspective
WANJIRU. DRGITARIPATRICIA. "Tris(2-pyridyl) phosphine oxide; how C-H.". In: Acta Crystallographica C. International Union of Crystallography; 2004. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
WANJIRU. DRGITARIPATRICIA. "Synthesis and characterization of alkyltris(2-pyridyl)phosphonium salts.". In: Phosphorus, Sulphur, and Silicon and the Related Elements. Taylor & Francis; 2006. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
WANJIRU. DRGITARIPATRICIA. "Synthesis and reactions of mixed N, P ligands.". In: European Journal of Inorganic Chemistry. Wiley Interscience; 2005. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
WANJIRU. DRGITARIPATRICIA. "Antimalarial Pyrido[1,2-a]benzimidazoles.". In: 5th African Crop Science Society International Conference in Lagos Nigeria October 21-26 2001. American Chemical Society; 2011. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
WANJIRU. DRGITARIPATRICIA. "2, 2.". In: Acta Crystallographica C. International Union of Crystallography; 2004. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
WANJIRU. DRGITARIPATRICIA. "A substance or composition for the treatment of cancer.". In: European Patent Office. World Intellectual Property Organisation; 2009. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
Wanjiru Patricia G. Antimalarial Pyrido[1,2-a]benzimidazoles.; 2011.
WANJIRU DRGICHUHIAGNES. "Murang.". In: Measure Macro International, Maryland. John Benjamins Publishing Company; 2002. Abstract

Fresh blood lymphocytes from nine health donors have been compared with samples from the same donors, recovered after period of 2 to 21 months storage in liquid nitrogen, for the capacity to respond to a range of mitogens in vitro. A microculture assay was used, requireing aliquots of only 25,000 cells. The mean levels of 14C-thymidine uptake for fresh and frozen samples were closely comparable when the cells had been stimulated by PHA, Pokeweed or mitomycin-C-treated allogeneic lymphoblastoid cells. Lymphocytes from six East African donors, frozen by a very simple technique, were recovered after 3 or more years storage in liquid nitrogen. Five of the samples were in good condition as judged by cell viability and the capacity to form spontaneous 'E' rosettes with sheep erythrocytes. These five samples also responded extremely well to PHA, PWM and mitomycin-C-treated allogeneic lymphoblastoid cells using the microculture assay. This study extends the range of applications of cell banks in which small aliquots of blood lymphocytes are stored in liquid nitrogen for periods of several years.

Wanjiru TM. "Nairobi.". 2012.Website
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W. (1996) contribution on rabies and worms in .". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1996. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU MRSKARIUKILUCY, KINYUA DRNGUUEDWARD, W. DRKINYANJUIPETER, BULIMO DRDIMBUSONWALLACE. "L.W. Kariuki, E.K. Nguu, R.M. Njogu, P. W. Kinyanjui, J.O.Midiwo, W.D. Bulimo, J.K.Kiaira. MAESANIN: A BENZOQUINONE FROM MAESA LANCEOLATA THAT COMPLETELY INHIBITS RESPIRATION IN BLOODSTREAM TRYPANOSOMA BRUCEI BRUCEI.". In: 5th International Congress of the African Association of Physiological Sciences (AAPS). ELSAYED EL BANHAWY,1 L. IRUNGU1 & H. MUGO2; 2008.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W., Skoglund, L.A., Skjelbred, P. and Lokken, P. (1988): Effects of a glucocorticoid in the post-operative course following experimented orthopaedic surgery in dogs. Acta. Vet. Scand. 29, 415-419.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1988. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Justus Nyameyio Agoti, The impact of dividend announcements on firm value: An event study of the case of the NSE, University of Nairobi, 2004." The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2004.
WANJIRU DRNGUGIROSE. "Rose W. Ngugi, Victor Murinde, and Christopher Green, , Key microstructure and policy issues for emerging stock markets. What have we learned? Finance and Development Research Programme Working Paper # 16 May, ISBN 1902518780, Being revised for the SUERF .". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2000. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
Wanjiru KG. "Instructional Resources for preschool children; Teaching Children: Ahandbook for preschool teachers. .". In: A handbook for preschool teachers. NAIROBI: Vidic Investment Ltd. ; 2014.
WANJIRU PROFMBUGUASUSAN. "Mande, J.D., I.B.J. Buoro, S.W. Mbugua and P.M.F. Mbithi (2002) Experimental Models of Osteoarthritis. A Review The Kenya Vet. (23) 67-69.". In: East Afri. Med J. 1988 May; 65(5):330-4. IBIMA Publishing; 2002. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W., Skoglund, L.A., Djoseland, O. and Lokken, P. (1988): Adrenocortical suppression by a glucocorticoid: Effect of a single i.m. injection of betamethasone depot versus placeto given prior to orthopaedic surgery in dogs. Acta. Vet. Scand., 29, 4.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1988. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Growth of the NSE primary market: what can we learn? KIPPRA Discussion Paper # 47." The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2005.
Wanjiru KG. "Computer Based Instruction and Gender effect on learners’ performance in Art and Design in public secondary schools in Kenya." International Journal of Education and Research.. 2017;5(6):ISSN:2309-0404 .
WANJIRU PROFMBUGUASUSAN. "Bwangamoi, O., Buoro, I.B.J., Price, J.E., DaCosta, R.P.R. and Mbugua, S.W., (1989). Natural Trypanosoma Vivax infection in a domestic cat in Nairobi. Bull. An. Hlth. and prod. in Africa, Special Issue, 147-157.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1989. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU MRSKARIUKILUCY, KINYUA DRNGUUEDWARD, W. DRKINYANJUIPETER, BULIMO DRDIMBUSONWALLACE. "L.W. Kariuki, E.K. Nguu, R.M. Njogu, P. W. Kinyanjui, J.O.Midiwo, W.D. Bulimo, J.K.Kiaira. MAESANIN: A BENZOQUINONE FROM MAESA LANCEOLATA THAT COMPLETELY INHIBITS RESPIRATION IN BLOODSTREAM TRYPANOSOMA BRUCEI BRUCEI.". In: 5th International Congress of the African Association of Physiological Sciences (AAPS). MBA; 2008.
WANJIRU DRNGUGIROSE. "Rose W. Ngugi , Development of the NSE: A historical perspective, KIPPRA Discussion Paper # 27.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2003. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Karim, F., Kanui, T.I. and, Mbugua S.W.(1993). Effects of codein, naproxen and dexamethasone on formalin-induced pain in the naked mole rat (Heterocephalus Glaber). Nuero Report. Vol.1, No.1, Pg.25-28.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1993. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Rose W. Ngugi , Determinants of Interest rate spread in Kenya, African Journal of Economic Policy.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2003. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU DRNGUGIROSE. "Njuguna Isaac Kiambo; an empirical study of the efficient market hypothesis on the NSE, 1998, University of Nairobi.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1998. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W., (1994). Establishing a breeding kennel; Care of the bitch and neonates. Kenya Veterinary Association - Central Branch scientific meeting.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1994. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Ndiritu, C.G., S.W. Mbogwa, P.D. Sayer (1977) Extragenitally located transmissible venereal tumour in dogs. Modern Vet. Practice. 940-946.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1977. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRGICHUHIAGNES. "Gichuhi, W. and E. K. Bauni.". In: Measure Macro International, Maryland. John Benjamins Publishing Company; 1998. Abstract

Fresh blood lymphocytes from nine health donors have been compared with samples from the same donors, recovered after period of 2 to 21 months storage in liquid nitrogen, for the capacity to respond to a range of mitogens in vitro. A microculture assay was used, requireing aliquots of only 25,000 cells. The mean levels of 14C-thymidine uptake for fresh and frozen samples were closely comparable when the cells had been stimulated by PHA, Pokeweed or mitomycin-C-treated allogeneic lymphoblastoid cells. Lymphocytes from six East African donors, frozen by a very simple technique, were recovered after 3 or more years storage in liquid nitrogen. Five of the samples were in good condition as judged by cell viability and the capacity to form spontaneous 'E' rosettes with sheep erythrocytes. These five samples also responded extremely well to PHA, PWM and mitomycin-C-treated allogeneic lymphoblastoid cells using the microculture assay. This study extends the range of applications of cell banks in which small aliquots of blood lymphocytes are stored in liquid nitrogen for periods of several years.

WANJIRU DRNGUGIROSE. "Owen Nyango'ro, Tax and Capital structure: Case of listed firms in Kenya, University of Nairobi, 2003.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2003. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Perry, B.D., Kyendo, T.M., Mbugua, S.W., Price, J.E. and Varma, S.(1995). Increasing rabies vaccination coverage in urban dog populations of high human population density suburbs - A case study in Nairobi, Kenya.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1995. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W., (1987). Steroidal and non-steroidal anti-inflammatories in surgery. Paper presented during Kenya Veterinary Association - Coast Branch scientific meeting in Mombasa.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1987. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRGICHUHIAGNES. "Gichuhi, Wanjiru, Sarah Bradley and Karen Hardee. 2004. Provision and Use of Family Planning in the Context of HIV/AIDS in Kenya: Perspectives of Providers, Family Planning and Antenatal Care Clients and HIV-Positive Women.". In: Policy Project, Futures Group. International, Washington DC. John Benjamins Publishing Company; 2004. Abstract

Fresh blood lymphocytes from nine health donors have been compared with samples from the same donors, recovered after period of 2 to 21 months storage in liquid nitrogen, for the capacity to respond to a range of mitogens in vitro. A microculture assay was used, requireing aliquots of only 25,000 cells. The mean levels of 14C-thymidine uptake for fresh and frozen samples were closely comparable when the cells had been stimulated by PHA, Pokeweed or mitomycin-C-treated allogeneic lymphoblastoid cells. Lymphocytes from six East African donors, frozen by a very simple technique, were recovered after 3 or more years storage in liquid nitrogen. Five of the samples were in good condition as judged by cell viability and the capacity to form spontaneous 'E' rosettes with sheep erythrocytes. These five samples also responded extremely well to PHA, PWM and mitomycin-C-treated allogeneic lymphoblastoid cells using the microculture assay. This study extends the range of applications of cell banks in which small aliquots of blood lymphocytes are stored in liquid nitrogen for periods of several years.

WANJIRU DRNGUGIROSE. "Njuguna Ndung'u and Rose W. Ngugi. Banking Sector Interest Rate Spread in Kenya. KIPPRA Discussion Paper # 5.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2000. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
Wanjiru KG. Art and Craft for early childhood education (Module). . NAIROBI: University of Nairobi: Open and Distance learning.; 2012.
WANJIRU PROFMBUGUASUSAN. "Mande, J.D., , I.B.J. Buoro, P.M.F. Mbithi, and S.W. Mbugua (2002) Polysulfated Glycosaminoglycans in the Treatment of Osteoarthritis: A Review. The Kenya Vet.(23) 70-71.". In: East Afri. Med J. 1988 May; 65(5):330-4. IBIMA Publishing; 2002. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mburu, D.N., Mbugua, S.W., Skoglund, L.A and lokken, P. (1988): Effects of paracetamol and acetylsalicylic acid on the post-operative course after experimental orthopaedic surgery in dogs. J.Vet. Pharmacol. Therap. 11, 163-171.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1988. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE, Ngugi RW. "Luka Kandie Kiptui, Exchange rate pass-through to domestic prices in Kenya: 1972-2004, University of Nairobi, 2005." The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2004.
WANJIRU DRMWANGIJANE, G PROFGATEIDAVID. "Hepatitis B virus, hepatocellular carcinoma and liver cirrhosis in Kenya. East Afr Med J. 1993 Apr;70(4 Suppl):34-6.". In: East Afr Med J. 1993 Apr;70(4 Suppl):34-6. RIVERBRROKS COMMUNICATIONS; 1993. Abstract
Hepatocellular carcinoma is the third most common malignancy in Kenyan males occurring with a peak incidence at 40 years of age. A worldwide correlation has been noted between the incidence of hepatocellular carcinoma and prevalence of hepatitis B virus. Liver biopsies with histological diagnosis of hepatocellular carcinoma (HCC), cirrhosis and the normals were reviewed by the authors. They were then stained for hepatitis B surface antigen (HBsAg) and hepatitis e core antigen (HBcAg). Only 2.5% of normal livers were positive for HBsAg compared with 33% of HCC and 25% of cirrhosis respectively. Hepatitis core antigen was not demonstrated in normal liver biopsies but it was present in 11.5% of HCC and 14% of cirrhosis. Background cirrhosis was noted in 52% of biopsies showing HCC. It is clear that a causal association exists between hepatitis B virus (HBV) and both liver cirrhosis and hepatocellular carcinoma. Higher antigen markers, up to 80% have been reported in South East Asia and India. This difference may be due to the type of biopsy examined (needle biopsy vs open biopsy) but the possibility that other factors such as aflatoxin and non A/non B hepatitis viruses play a more significant role in the causation of liver disease in Kenya than has previously been assumed should be explored.
WANJIRU DRNGUGIROSE. "Rose W. Ngugi, An Empirical Analysis of Interest Rate Spread in Kenya. AERC Research Paper # 106.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2001. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
Wanjiru KG, Samwel Owino Mwanda, Ronnie Midigo. "Computer Based Instruction and Learner Achievement; Implications for Training Art and Design in Kenya’s Secondary Schools." Journal of Academic Research. . 2017;5(5):19-31.
WANJIRU PROFMBUGUASUSAN. "Mande, D.J., P.M.F.Mbithi, S.W. Mbugua.I.B.J. Buoro and P. K. Gathumbi (2003) Volume of the Ligamentum Capitis Femoris in Osteoarthritic Hip Joints of Adult Dogs. J. S. Afr.Vet. Ass. 74 (1) 11-13.". In: East Afri. Med J. 1988 May; 65(5):330-4. IBIMA Publishing; 2003. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W., Skoglund, L.A. and Lokken, P. (1989): Effects of phenylbutazone and indomethacin on the post-operative course following experimental orthopaedic surgery in dogs. Acta. Vet. Scand., 30, 27-35.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1989. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Deregulation and management of interest rates, IPAR Discussion Paper # 38." The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2003.
WANJIRU DRNGUGIROSE. "Rose, W. Ngugi, Ikiara, M. M. and Makhoha J., 1996. Solid waste management in the city of Nairobi, perceptions, practices, and possibilities, SYLFF Working Paper # 2 November (JREX International Award Winning Research Paper, a condition for the publicatio.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1996. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W. (1993). A Perspective of the Kenya Veterinary Board on curriculum development and veterinary needs into the 21st century. Kenya Veterinary Association annual scientific meeting in Nairobi.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1993. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU MRSKARIUKILUCY, KINYUA DRNGUUEDWARD, W. DRKINYANJUIPETER, BULIMO DRDIMBUSONWALLACE. "L.W. Kariuki, E.K. Nguu, R.M. Njogu, P. W. Kinyanjui, J.O.Midiwo, W.D. Bulimo, J.K.Kiaira. MAESANIN: A BENZOQUINONE FROM MAESA LANCEOLATA THAT COMPLETELY INHIBITS RESPIRATION IN BLOODSTREAM TRYPANOSOMA BRUCEI BRUCEI.". In: 5th International Congress of the African Association of Physiological Sciences (AAPS). Heinrich Boll Foundation.; 2008.
WANJIRU DRNGUGIROSE. "Makoma, L. Wanza; the demand for municipal solid waste disposal services; An econometric analysis of willingness to pay; 1998, University of Nairobi.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1998. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W. (1994) Rabies: A practical approach. Presented in 3 workshops ( Ngecha, Gatundu and Kathiani in Kenya) for the Kenya Veterinary Association.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1994. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mbogwa S.W., J.G Wandera: ( 1977). Lymphosarcoma in Dog: A case report. The Kenya Veterinarian Vol. 1. No. 2 pg 15-16.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1977. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRGICHUHIAGNES. "Gichuhi, W.". In: Measure Macro International, Maryland. John Benjamins Publishing Company; 1993. Abstract

Fresh blood lymphocytes from nine health donors have been compared with samples from the same donors, recovered after period of 2 to 21 months storage in liquid nitrogen, for the capacity to respond to a range of mitogens in vitro. A microculture assay was used, requireing aliquots of only 25,000 cells. The mean levels of 14C-thymidine uptake for fresh and frozen samples were closely comparable when the cells had been stimulated by PHA, Pokeweed or mitomycin-C-treated allogeneic lymphoblastoid cells. Lymphocytes from six East African donors, frozen by a very simple technique, were recovered after 3 or more years storage in liquid nitrogen. Five of the samples were in good condition as judged by cell viability and the capacity to form spontaneous 'E' rosettes with sheep erythrocytes. These five samples also responded extremely well to PHA, PWM and mitomycin-C-treated allogeneic lymphoblastoid cells using the microculture assay. This study extends the range of applications of cell banks in which small aliquots of blood lymphocytes are stored in liquid nitrogen for periods of several years.

WANJIRU DRNGUGIROSE. "Rose W. Ngugi, Health Seeking Behavior in Reform Process for Rural Households The Case of Mwea-Kirinyaga District. AERC Research paper # 95.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1999. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU MRSKARIUKILUCY, KINYUA DRNGUUEDWARD, W. DRKINYANJUIPETER, BULIMO DRDIMBUSONWALLACE. "L.W. Kariuki, E.K. Nguu, R.M. Njogu, P. W. Kinyanjui, J.O.Midiwo, W.D. Bulimo, J.K.Kiaira. MAESANIN: A BENZOQUINONE FROM MAESA LANCEOLATA THAT COMPLETELY INHIBITS RESPIRATION IN BLOODSTREAM TRYPANOSOMA BRUCEI BRUCEI.". In: 5th International Congress of the African Association of Physiological Sciences (AAPS). Kisipan, M.L.; 2008.
WANJIRU DRWANGARIVERONICA. "KNOWLEDGE, ATTITUDES AND PERCEPTIONS OF PARENTS OF CHILDREN AGED 3-12 ON ASSOCIATION OF THUMB SUCKING, TONGUE THRUSTING AND ANTERIOR OPEN BITE.". In: oral health sciences journal. Wangari Veronica Wanjiru; 2009.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W.(1995) The role of the Kenya Veterinary Board in the veterinary profession. Paper presented in the Kenya Veterinary Association Annual Scientific Conference..". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1995. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Nyaga, P.W., S.M. Njiro, C.G. Ndiritu, S.W. Mbugua (1980) Pulmonary geotrichosis in Kenya: Bulletin of Animal Production in Africa, Vol, 4 No. 1 pg 6-9.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1980. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRGICHUHIAGNES. "Malawi National Strategic Framework HIV/AIDS Programme: Monitoring and Evaluation Plan,National Aids Commission.". In: Measure Macro International, Maryland. John Benjamins Publishing Company; 2002. Abstract

Fresh blood lymphocytes from nine health donors have been compared with samples from the same donors, recovered after period of 2 to 21 months storage in liquid nitrogen, for the capacity to respond to a range of mitogens in vitro. A microculture assay was used, requireing aliquots of only 25,000 cells. The mean levels of 14C-thymidine uptake for fresh and frozen samples were closely comparable when the cells had been stimulated by PHA, Pokeweed or mitomycin-C-treated allogeneic lymphoblastoid cells. Lymphocytes from six East African donors, frozen by a very simple technique, were recovered after 3 or more years storage in liquid nitrogen. Five of the samples were in good condition as judged by cell viability and the capacity to form spontaneous 'E' rosettes with sheep erythrocytes. These five samples also responded extremely well to PHA, PWM and mitomycin-C-treated allogeneic lymphoblastoid cells using the microculture assay. This study extends the range of applications of cell banks in which small aliquots of blood lymphocytes are stored in liquid nitrogen for periods of several years.

WANJIRU DRNGUGIROSE. "Kiragu M.R.; Market concentration and firm's profitability in the food processing sub-sector, 1999, University of Nairobi.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1999. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Mbugua, S.W., A. Bencivenga,S. Varma, J. Wambua, E. Wambua, T. Manyibe and G. Muchemi (1998) Repair of Posterior Cruciate and Collateral Ligaments Rupture in a Male Cheetah.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1998. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mburu, D.N., Mbugua, S.W., Skoglund, L.A and lokken, P. (1988): Effects of paracetamol and acetylsalicylic acid on the post-operative course after experimental orthopaedic surgery in dogs. J.Vet. Pharmacol. Therap. 11, 163-171.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1988. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Rose W. Ngugi. Financial Reform Process in Kenya 1989-1996, African Development Review.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2000. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Mande, D.J., P.M.F.Mbithi, S.W. Mbugua.I.B.J. Buoro and P. K. Gathumbi (2003) Volume of the Ligamentum Capitis Femoris in Osteoarthritic Hip Joints of Adult Dogs. J. S. Afr.Vet. Ass. 74 (1) 11-13.". In: East Afri. Med J. 1988 May; 65(5):330-4. IBIMA Publishing; 2003. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Bwangamoi, O., price, J.E., Mbugua, S.W., Mbaka, M. Gathumbi, P. and DaCosta, R.P.R. (1989): An Outbreak of canine distemper in Nairobi. Bull. Anim. Hlth. and Prod. in Africa, Special Issue, 79-86.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1989. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Yong Yoon; World economic booms and crisis, adjustment policies and the current account: A decomposition analysis for Kenya 1972-1993, University of Nairobi.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1993. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
Wanjiru KG, Digolo Patrick Ochieng Obonyo, Boniface N, Owino MS. "Effect of Computer Based Instruction on Learners’ Performance in Art and Design in public secondary schools in Kenya. ." The International Journal of Humanities & Social Studies.. 2017;5(6).
WANJIRU PROFMBUGUASUSAN. "Njuki, P.K., Gathumbi, P.K. and Mbugua, S.W., (1991): Tyzzer.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1991. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Rose W. Ngugi, What defines the liquidity of stock market? The case for Nairobi Stock Exchange, KIPPRA Discussion Paper # 29.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 2003. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU DRNGUGIROSE. "Chacha, R. Njeri; Factors determining the development of NSE, 1998, University of Nairobi.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1998. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Karim, F., Kanui, T.I. and Mbugua S.W.(1993). Effects of pethidine, acetylsalicylic acid and hydrocortisone on formalin-induced pain in the naked mole rat (Heterocephalus Glaber). African Journal of Neurosciences,Vol.1,No.1,Pg.91.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1993. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Muhammed S.I., S.W. Mbogwa: ( 1974) :Isolation of Microsporum nanum from a dog with skin lesions. The Vet. Rec. Dec. 574.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1974. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU DRNGUGIROSE. "Onyancha C.; Are foreign exchange and stock markets related? An empirical analysis of the Kenyan case, 1998, University of Nairobi.". In: Paris 2011 World Cup in Paris, France. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1998. Abstract
In contrast with mammalian cells, little is known about the control of Ca2+ entry into primitive protozoans. Here we report that Ca2+ influx in pathogenic Trypanosoma brucei can be regulated by phospholipase A2 (PLA2) and the subsequent release of arachidonic acid (AA). Several PLA2 inhibitors blocked Ca2+ entry; 3-(4-octadecyl)-benzoylacrylic acid (OBAA; IC50 0.4+/-0.1 microM) was the most potent. We identified in live trypanosomes PLA2 activity that was sensitive to OBAA and could be stimulated by Ca2+, suggesting the presence of positive feedback control. The cell-associated PLA2 activity was able to release [14C]AA from labelled phospholipid substrates. Exogenous AA (5-50 microM) also initiated Ca2+ entry in a manner that was inhibited by the Ca2+ antagonist La3+ (100 microM). Ca2+ entry did not depend on AA metabolism or protein kinase activation. The cell response was specific for AA, and fatty acids with greater saturation than tetraeicosanoic acid (AA) or with chain lengths less than C20 exhibited greatly diminished ability to initiate Ca2+ influx. Myristate and palmitate inhibited PLA2 activity and also inhibited Ca2+ influx. Overall, these results demonstrate that Ca2+ entry into T. brucei can result from phospholipid hydrolysis and the release of eicosanoic acids.
WANJIRU PROFMBUGUASUSAN. "Mbithi, P.M.F., Mbiuki, S.M., Mbugua, S.W. and Mitema, E. (1994). Pseudoarthrosis and arthrodesis of the bovine fetlock. Tanzania Vet. Journal.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1994. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRU PROFMBUGUASUSAN. "Mbogwa S.W., W.V Lumb, K.W. Smith: . (1978) Plating of Canine Scapular Fractures: Am. J. Vet. ResVol. 39 No. 8: 1327-1330.". In: Proceedings: Biannual Conference of the Faculty of Veterinary Medicine. IBIMA Publishing; 1978. Abstract
Measurement of tooth lengths was carried out on 537 extracted human teeth. The teeth were collected from adults aged 17 years and above and preserved in formalin. The tooth lengths were obtained by taking measurements off calibrated graph paper. The lengths obtained in this study were comparable to previous data reported in the literature. However, this new data will provide useful guidelines in Kenya for the management of endodontic patients especially in the purchase and stocking of the most appropriate endodontic instruments.
WANJIRA DRNJUGUNAPAMELA. "Validity and reliability of the 'Ten Questions' questionnaire for detecting moderate to severe neurological impairment in children aged 6-9 years in rural Kenya. Mung'ala-Odera V, Meehan R, Njuguna P, Mturi N, Alcock K, Carter JA, Newton CR.Neuroepidemiol.". In: Neuroepidemiology. 2004 Jan-Apr;23(1-2):67-72. East African Medical Journal; 2004. Abstract

BACKGROUND: The 'Ten Questions' Questionnaire (TQQ) is used to detect severe neurological impairment in children living in resource-poor countries. Its usefulness has been established in Asia and the Caribbean, but there are a few published studies from Africa. We evaluated the TQQ as part of a larger study of neurological impairment in a rural community, on the coast of Kenya. METHODS: The study was conducted in two phases from June 2001 to May 2002; in phase one, a community household screening of 10,218 children aged 6-9 years using the TQQ was performed. Phase two involved a comprehensive clinical and psychological assessment of all children testing positive on the TQQ (n = 810) and an equivalent number of those testing negative (n = 766). Data were interpreted using the impairment-specific approach. RESULTS: Overall, the sensitivity rates for screening the different impairments were: cognitive (70.0%), motor (71.4%), epilepsy (100%), hearing (87.4%) and visual (77.8%). All the specificity rates were greater than 96%. However, the positive predictive values were low, and ranged from 11 to 33%. CONCLUSIONS: These results are similar to those from other continents and provide evidence that the TQQ can be used to compare the epidemiology of moderate/severe impairment in different parts of the world. Furthermore, the TQQ can be used to screen for moderately/severely impaired children in resource-poor countries; however, the low positive predictive values mean that other assessments are required for confirmation. Copyright 2004 S. Karger AG, Basel

WANJIRA DRNJUGUNAPAMELA. "Prevalence and risk factors of neurological disability and impairment in children living in rural Kenya. Mung'ala-Odera V, Meehan R, Njuguna P, Mturi N, Alcock KJ, Newton CR.Int J Epidemiol. 2006 Jun;35(3):683-8. Epub 2006 Feb 21.". In: Int J Epidemiol. 2006 Jun;35(3):683-8. Epub 2006 Feb 21. East African Medical Journal; 2006. Abstract
BACKGROUND: There is little data on the burden of neurological impairment (NI) in developing countries, particularly in children of Africa. METHODS: We conducted a survey of NI in children aged 6-9 years in a rural district of Kenya. First, we screened for neurological disability by administering the Ten Questions Questionnaire (TQQ) to parents/guardians of children in a defined population. In phase two, we performed a comprehensive clinical and psychological assessment on children who tested positive on TQQ and on a similar number of children who tested negative. RESULTS: A total of 10 218 children were screened, of whom 955 (9.3%) were positive on TQQ. Of these, 810 (84.8%) were assessed, and of those who tested negative 766 (8.3%) were assessed. The prevalence for moderate/severe NI was 61/1000 [95% confidence interval (95% CI) 48-74]. The most common domains affected were epilepsy (41/1000), cognition (31/1000), and hearing (14/1000). Motor (5/1000) and vision (2/1000) impairments were less common. Of the neurologically impaired children (n = 251), 56 (22%) had more than one impairment. Neonatal insults were found to have a significant association with moderate/severe NI in both the univariate [odds ratio (OR) = 1.70; 95% CI 1.12-2.47] and multivariate analyses (OR = 1.30; 95% CI 1.09-1.65). CONCLUSIONS: There is a considerable burden of moderate/severe NI in this area of rural Kenya, with epilepsy, cognition, and hearing being the most common domains affected. Neonatal insults were identified as an important risk factor.
WANJIRA DRNJUGUNAPAMELA. "Computerized tomography scan of the brain in a community study of neurological impairment in Kenya. Njuguna PW, Mungala-Odera V, Chong WK, Meehan RA, Newton CR. J Child Neurol. 2007 Jan;22(1):26-32.". In: J Child Neurol. 2007 Jan;22(1):26-32. East African Medical Journal; Submitted. Abstract
Neurological impairment is common in resource-poor countries, but its causes are not clear. Computerized tomography (CT) of the brain has been used to determine the cause of brain insults that may manifest as neurological impairments. The authors conducted a community survey in Kilifi of 10 218 children aged 6 to 9 years to detect neurological impairment. From this survey, 34 children were identified, of whom 16 had motor deficits, 11 complex partial seizures, 4 microcephaly or macrocephaly, and 3 severe developmental delay. These children were assessed with elicitation of history, physical examination, and CT scan of the brain. Sixteen (47%) of the scans showed abnormalities: cerebral atrophy (n = 9), schizencephaly (n = 3), periventricular leukomalacia (n = 2), porencephalic cyst (n = 1), and agenesis of the corpus callosum (n = 1). The minimum prevalence of abnormalities on the CT scan of the brain is 1.56 of 1000, and the prevalence of schizencephaly is 0.29 of 1000. Motor impairments were more likely to show abnormality than the other indications. CT abnormalities are common in children with neurological impairment in Kenya, but the appearances did not identify a major cause.
WANJIRA DRNJUGUNAPAMELA. "Perturbations in electrolyte levels in kenyan children with severe malaria complicated by acidosis. Maitland K, Pamba A, Fegan G, Njuguna P, Nadel S, Newton CR, Lowe B.Clin Infect Dis. 2005 Jan 1;40(1):9-16. Epub 2004 Dec 6.". In: Clin Infect Dis. 2005 Jan 1;40(1):9-16. Epub 2004 Dec 6. East African Medical Journal; 2004. Abstract
BACKGROUND: To date, information about the frequency of electrolyte disturbances among children with severe falciparum malaria is limited. METHODS: We describe changes in potassium, calcium, magnesium, and phosphate levels in 56 Kenyan children (42 who survived and 14 who died) admitted to the hospital with clinical features of severe malaria (impaired consciousness or deep breathing) complicated by acidosis (base deficit, >8 mmol/L). RESULTS: Mild-to-moderate hypercalcemia was common at admission, particularly among children with severe anemia. Severe hyperkalemia complicated falciparum malaria in 9 children (16%), of whom 7 (78%) died, generally soon after admission. Hypokalemia, hypomagnesemia, and hypophosphatemia were uncommon (<7% of children) at admission but developed in >30% of children within 24 h. Hypocalcemia was infrequent (<5% of children) at any time point. Apart from administration of potassium, electrolyte deficiencies were not corrected and were not associated with an adverse outcome. CONCLUSIONS: At admission to the hospital, hyperkalemia may complicate cases of acidosis due to severe malaria and is associated with high, early mortality. After admission, mild asymptomatic deficiencies in magnesium and phosphate levels were common but were not associated with any deleterious effect. Thus, routine correction when serial measurement of electrolyte levels cannot be performed is unwarranted. Asymptomatic potassium deficiency developed despite provision of this electrolyte at maintenance doses. Further studies are justified but are unlikely to be a major research priority because, as these data suggest, the impact on mortality would at most be limited.
WANJIRA DRNJUGUNAPAMELA. "Management of severe falciparum malaria. Njuguna P, Newton C. J Postgrad Med. 2004 Jan-Mar;50(1):45-50.". In: J Postgrad Med. 2004 Jan-Mar;50(1):45-50. East African Medical Journal; 2004. Abstract
Plasmodium falciparum is the most common cause of severe and life-threatening malaria. Falciparum malaria causes over one million deaths every year. In Africa, a vast majority of these deaths occur in children under five years of age. The presentation of severe malaria varies with age and geographical distribution. The mortality rate is higher in adults than in children but African children develop neuro-cognitive sequelae following severe malaria more frequently. The management of severe malaria includes prompt administration of appropriate parenteral anti-malarial agents and early recognition and treatment of the complications. In children, the complications include metabolic acidosis (often caused by hypovolaemia), hypoglycaemia, hyperlacticacidaemia, severe anaemia, seizures and raised intracranial pressure. In adults, renal failure and pulmonary oedema are more common causes of death. In contrast, concomitant bacterial infections occur more frequently in children and are associated with mortality in children. Admission to critical or intensive care units may help reduce the mortality, and the frequency and severity of sequelae related to severe malaria.
WANJIRA DRNJUGUNAPAMELA. "Prevalence, incidence and risk factors of epilepsy in older children in rural Kenya.Mung'ala-Odera V, White S, Meehan R, Otieno GO, Njuguna P, Mturi N, Edwards T, Neville BG, Newton CR. Seizure. 2008 Jul;17(5):396-404. Epub 2008 Jan 14.". In: Seizure. 2008 Jul;17(5):396-404. Epub 2008 Jan 14. East African Medical Journal; 2008. Abstract
BACKGROUND: There is little data on the burden or causes of epilepsy in developing countries, particularly in children living in sub-Saharan Africa. METHODS: We conducted two surveys to estimate the prevalence, incidence and risk factors of epilepsy in children in a rural district of Kenya. All children born between 1991 and 1995 were screened with a questionnaire in 2001 and 2003, and those with a positive response were then assessed for epilepsy by a clinician. Active epilepsy was defined as two or more unprovoked seizures with one in the last year. RESULTS: In the first survey 10,218 children were identified from a census, of whom 110 had epilepsy. The adjusted prevalence estimates of lifetime and active epilepsy were 41/1000 (95% CI: 31-51) and 11/1000 (95% CI: 5-15), respectively. Overall two-thirds of children had either generalized tonic-clonic and/or secondary generalized seizures. A positive history of febrile seizures (OR=3.01; 95% CI: 1.50-6.01) and family history of epilepsy (OR=2.55; 95% CI: 1.19-5.46) were important risk factors for active epilepsy. After the second survey, 39 children from the same birth cohort with previously undiagnosed epilepsy were identified, thus the incidence rate of active epilepsy is 187 per 100,000 per year (95% CI: 133-256) in children aged 6-12 years. CONCLUSIONS: There is a considerable burden of epilepsy in older children living in this area of rural Kenya, with a family history of seizures and a history of febrile seizures identified as risk factors for developing epilepsy.
Wanjira J, Ndiwa TC, Gichuki N, Wykstra M. "Evaluating the efficacy of flashing lights in deterring livestock attacks by predators: a case study of Meibae Community Conservancy, Northern Kenya." East African Journal of Science, Technology and Innovation. 2021;2(3).
Wanjiku Ng’ang’a AL, Carlson L. "Multilingual Generation of Live Math Problems in WebALT." In: Mika Seppälä, Sebastian Xambo OC, ed. Proceedings of the First WebALT Conference and Exhibition.; 2006:. Abstract
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Wanjiku Ng'ang'a, Anni Laine LC. Natural Language Generation from OpenMath.; 2006. Abstract
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WANJIKU DRMUMENYASIPHILA. "Mumenya S.W., Tait R.B. and Alexander M.G.: Mechanical behavior of textile concrete under accelerated ageing conditions.". In: Research paper submitted to Cement and Concrete Composites journal. Materials Research Society; 2003. Abstract
1. Singh C. B.  .  August . .
WANJIKU DRNJUGUNAMARGARET. "Njuguna M, Msukwa G, Shilio B, Tumwesigye C, Courtright P, Lewallen S. Causes of severe visual impairment and blindness in children in schools for the blind in eastern Africa: changes in the last 14 years. Ophthalmic Epidemiol. 2009 May-Jun;16(3):151-5.". In: East African Journal of Ophthalmology. Livestock Research for Rural Development; 2009. Abstract

PURPOSE: To determine the causes of severe visual impairment and blindness in children attending schools for the blind in Kenya, Malawi, Uganda, and Tanzania and to compare the findings with those of a 1994 study. METHODS: Children attending schools for the blind or annexes in 4 eastern African countries were examined. The major anatomical site of and underlying etiology of severe visual impairment and blindness was recorded using the standardized World Health Organization (WHO) reporting form. RESULTS: A total of 1062 children aged below 16 years were examined of whom 701 (65.2%) had severe visual impairment or blindness. The major anatomical sites of visual loss overall (% and 95% CI) were cornea scar/phthisis bulbi (19%,16.1-21.9), whole globe lesions (15.7%,13.0-18.4), retina (15.4 %, 12.7-18.1), lens related disorders (13.1%, 10.7-15.5), and optic nerve disorders (12.3%, 9.9-14.7). Corneal scar/phthisis was not distributed equally among the countries and was highest in Malawi, similar to findings in 1995. The major etiology of visual loss was childhood factors (29.9%) and an estimated 40% of severe visual impairment and blindness was due to potentially avoidable causes. CONCLUSION: The major causes of severe visual impairment and blindness overall have not changed appreciably since 1995. There are important differences among countries, however, and using overall estimates for planning may be misleading.

PMID: 19437309 [PubMed - indexed for MEDLINE]

WANJIKU DRMUMENYASIPHILA. "Mumenya S.W., Tait R.B. and Alexander M.G.: An appropriate specimen geometry for direct tensile testing of textile concrete.". In: Proceedings of 3rd Young Concrete Engineers, Practitioners and Technologists, pp. 1-10, Cape Town and Mindrand, 2006. Materials Research Society; 2006. Abstract
1. Singh C. B.  .  August . .
Wanjiku J;, Ackello – Ogutu C;, Kimenye LN;, Place F. "Socio-economic Factors Influencing Use Of Improved Fallows In Crop Production By Small-scale Farmers In Western Kenya."; 2003. Abstract

Abstract This study analysed the factors influencing the intensity of adoption of improved fallows in Western Kenya. Three hundred farmers were interviewed. Descriptive results showed the adopters to be older, more educated and had more contact with technology promoters than the non-adopters. Partial budgets were constructed and marginal rates of returns (MRR) showed that the technology is profitable. Based on the censored Tobit, the results indicate that the intensity of adoption was significantly influenced by age, experience of the household head and spouse, total land area, contact with technology promoters, technology profitability and use of other soil fertility replenishment options. It is recommended that education efforts be intensified. There is need to strengthen contact with the technology promoters. In order to ensure information flow to all, there is need for improvement in the approach and methods employed in on-farm research. Further, there is need to establish and strengthen networks of information exchange among relevant and interested organisation

Wanjiku PW, Moturi CA. Cloud Computing: Transforming Medium and High Tech Industries in Kenya. Durban, South Africa; 2016. Abstract

Cloud Computing provides novel perspectives in internetworking technologies and has the potential to dramatically change business models. This study aimed at establishing Cloud Computing adoption in Medium and High Tech Industries in Kenya, with an ultimate intention of recommending an appropriate model for its adoption. Using questionnaires, data was collected from 126 Medium and High Tech Industries within Nairobi and interviews were conducted with 25 Cloud Computing providers. Data analysis was done using SPSS and qualitative content analysis. Approximately 70% of cloud users and providers had recognized Cloud Computing as a force that is reshaping ICT and powering innovation. The major factors influencing the adoption of Cloud Computing were identified as cost, performance and reliability of The Cloud application. After analysis of four existing models for technology adoption, the Unified Theory of Acceptance and Use of Technology (UTAUT) model is recommend for adoption of Cloud Computing.

WANJIKU DRMUMENYASIPHILA. "Mumenya S.W., Tait R.B. and Alexander M.G.: Evaluation of pseudo-ductile behavior of textile concrete.". In: Research Paper aimed at Materials and Structures Journal. Materials Research Society; 2003. Abstract
1. Singh C. B.  .  August . .
WANJIKU DRNJUGUNAMARGARET. "Tumwesigye C, Msukwa G, Njuguna M, Shilio B, Courtright P, Lewallen S. Inappropriate enrollment of children in schools for the visually impaired in east Africa. Ann Trop Paediatr. 2009 Jun;29(2):135-9.". In: East African Journal of Ophthalmology. Livestock Research for Rural Development; 2009. Abstract

BACKGROUND: Many visually impaired children can learn to read print with appropriate training and simple visual aids. This may allow them to attend normal schools and to be integrated into society, which has lifelong benefits. Yet, in Africa, many visually impaired children are enrolled in special schools and taught only Braille. The purpose of this analysis was to document the extent of inappropriate enrollment of visually impaired children in special schools and annexes for the blind in four African countries. METHODS: Schools were selected through a population-proportional-to-size method so that they would represent all children attending special schools in Kenya, Malawi, Tanzania and Uganda. Children were examined by ophthalmologists trained in standardised methods to determine visual acuity and the cause of decreased acuity. RESULTS: Of 1062 children examined in special schools and annexes for the blind, 361 (34%, 95% CI 31.2, 36.8) had visual acuity >or=6/60; the most common cause of visual impairment was retinal disease. Of the 120 children with normal vision (>or=6/18), 69 (57.5%) had two normal eyes, 21 (17.5%) had an obvious ocular disfigurement in the fellow eye and 10 (8.4%) had had successful cataract surgery. CONCLUSIONS: In these countries, many children are placed inappropriately in special schools and annexes for the blind. The reasons are multiple and to rectify the situation will require advocacy and cooperation between ministries of health and education.

PMID: 19460267 [PubMed - indexed for MEDLINE]

WANJIKU DRMUMENYASIPHILA. "2. Tait R.B., Mumenya S.W., Alexander M.G., and Hourahane D.: Textile concrete provides special architectural and permanent shuttering opportunities.". In: Paper presented at the conference: Developing concrete to serve practical needs, Mindrand, South Africa, 13th -14th October 2004. Publication ISBN Number 1-920-01717-8 pp. 281-289. Materials Research Society; 2004. Abstract
1. Singh C. B.  .  August . .
WANJIKU DRNJUGUNAMARGARET, M DRWANYOIKEMILICENT. "Msiska V, Njuguna M, Kariuki M. Magnitude and pattern of significant refractive errors in primary school children of Ntcheu, a rural district in Malawi. East Afr. j. ophthalmol. 2009 Jul; 15(1): 18-20.". In: East African Journal of Ophthalmology. Livestock Research for Rural Development; 2009. Abstract

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Objectives: To determine the prevalence and pattern of significant refractive errors in rural primary school children.

 

Design: Cross sectional community based study.

 

Setting: Nine primary schools from Muluma, Kasinje and Bunyenga education zones in Ntcheu district, Malawi.

 

Subjects: One thousand two hundred and seventy eight primary school pupils aged 12

WANJIKU DRMUMENYASIPHILA. "Mumenya S.W., Tait R.B. and Alexander M.G.: Evaluation of toughness of textile concrete:.". In: Conference Paper to be presented to: Advanced Concrete Materials Conference at Stellenbosch, November 2009. Materials Research Society; 2009. Abstract
1. Singh C. B.  .  August . .
WANJIKU DRNJUGUNAMARGARET, STEPHEN DRGICHUHI. "Ocular injuries in children. East Afr Med J. 2008 Jan;85(1):39-45. PMID: 18543526 [PubMed - indexed for MEDLINE] Murithi I, Gichuhi S, Njuguna MW.". In: East Afr Med J. 2008 Jan;85(1):39-45. Livestock Research for Rural Development; 2008. Abstract

Department of Ophthalmology, College of Health Sciences, University of Nairobi, Nairobi, Kenya. OBJECTIVES: To describe the epidemiology, referral system and visual outcomes of eye injuries in children. DESIGN: Retrospective case series. SETTING: Kenyatta National Hospital (KNH) Nairobi, Kenya. SUBJECTS: Children aged upto 15 years with eye injuries hospitalised between January 1 st, 2000 and December 31st, 2004. RESULTS: There were 182 cases. Male: female ratio was 2:1. Median age was seven years (IQR 4-10) with bimodal peaks at four and seven years. The most common cause (35%) was sticks. One hundred and twenty seven cases (70%) were open- globe injuries. One hundred and fourty one (77%) presented with visual acuity worse than 6/60 seven eyes were badly damaged and were removed (evisceration enucleation). Ninety five children (52%) were referred from Central and Eastern provinces while 87 (48%) were from Nairobi province. Most [26 (31%)] cases in Nairobi were from Kibera, Dandora and Kariobangi. Median duration between injury and arrival at first medical facility was one day but three days from injury to KNH after referral. Only 29% got tetanus toxoid, antibiotics, analgesics or eyepads at the referring facility. Median hospitalisation was seven days with a median bill of KSh 5,275/= (US$ 70.00). Fourty four children (24%) had their bills waived for inability to pay. At the last recorded follow-up 81 (57%) children had better visual acuity, 16.9% had light perception (PL). Corneal scar was the most common complication. CONCLUSIONS: Eye injuries in KNH are severe, mostly affecting pre-school children from low-income settings. There is delay in arriving at KNH and inadequate care at the referring centres. Outcomes were poor although better than on admission. This may affect education, careers and quality-of-life. Injury-prevention programmes are recommended. PMID: 18543526 [PubMed - indexed for MEDLINE]

WANJIKU DRMUMENYASIPHILA. "Mumenya S.W., Tait R.B. and Alexander M.G.: Textile concrete: Preliminary mechanical characterization of a new ductile material.". In: Proceedings of Materials Research Society Conference, Witwatersrand, Johannesburg, 12th December 2003. Materials Research Society; 2003. Abstract
1. Singh C. B.  .  August . .
WANJIKU DRNJUGUNAMARGARET. "Msukwa G, Njuguna M, Tumwesigye C, Shilio B, Courtright P, Lewallen S. Cataract in children attending schools for the blind and resource centers in eastern Africa. Ophthalmology. 2009 May;116(5):1009-12.". In: East African Journal of Ophthalmology. Livestock Research for Rural Development; 2009. Abstract

OBJECTIVE: The aim of this study was to describe results of a representative sample of children who have undergone cataract surgery in schools for the blind in 4 African countries. DESIGN: Cross-sectional study. PARTICIPANTS: Children enrolled at schools for the blind in Kenya, Malawi, Tanzania, and Uganda. METHODS: We used a population-proportional-to-size methodology to select a representative sample of schools for the blind and annexes and included all the children attending the selected schools. Trained teams using standardized examination methods and a modified World Health Organization form examined the children. The form was modified specifically to collect information on outcomes of cataract surgery. MAIN OUTCOME MEASURES: Operative status and postoperative visual acuity. RESULTS: Of 1062 children examined, 196 (18%) had undergone cataract surgery or had cataract as the major cause of visual impairment; 140 (71%) had bilateral surgery, 24 (12%) had unilateral surgery, and 32 (16%) had not had surgery. Of operated eyes, 118 (41%) had visual acuity > or =20/200. Intraocular lenses were implanted in 65% of the operated eyes. Eyes with intraocular lens were more likely to have better vision than those without (P for trend = 0.04). Amblyopia was the most common cause of poor visual acuity in children who had undergone cataract surgery. CONCLUSIONS: The number of children in the schools who receive cataract surgery has increased greatly since 1995. The high rate of amblyopia highlights the critical need for programs to find children earlier and to ensure adequate follow-up after surgery. Without such programs, the value of training pediatric surgeons will not be fully realized. FINANCIAL DISCLOSURE(S): The authors have no proprietary or commercial interest in any materials discussed in this article.

PMID: 19410959 [PubMed - indexed for MEDLINE]

WANJIKU DRMUMENYASIPHILA. "Mumenya S.W., Tait R.B. and Alexander M.G.: Effect of environmental exposure on the microstructure of textile concrete.". In: Presented to the Seventh International RILEM Symposium on Fibre Reinforced Concrete: Design and applications (BEFIB 2008), Chennai, India, 17th -19th September 2008, pp. 293 -302. Materials Research Society; 2008. Abstract
1. Singh C. B.  .  August . .
Wanjiku J;, Manyengo JU;, Oluoch-Kosura W;. Gender differentiation in the analysis of alternative farm mechanization choices on small farms in Kenya.; 2007. AbstractWebsite

Using multinomial logit we analyze factors that influence the choice of mechanization technologies in Nyanza Province. The results show that farmers are aware of the attributes of the mechanization technologies, and that animal traction is the most commonly used. Gender, formal and informal training of the household head, and technology attributes influence the choice of mechanization technology. This study recommends increased formal and informal training, extension, credit, and tractor hire services to facilitate knowledge transfer, credit, and tractor availability. The study also recommends enactment of laws that increase women's access and control of productive resources.

Wanjeri JK, Kinoti M, Olewe THAM. "Risk factors for burn injuries and fire safety awareness among patients hospitalized at a public hospital in Nairobi, Kenya: A case control study." Burns. 2018;Jan 29(pii: S0305-4179(17)):Burns. 2018 30611-3. doi: 10.1016/j.burns.2017.11.007.
Wanjekeche E;, Imungi JK;, Karuri EG. "Effect of Soaking on the Cookability and Nutritional Quality of Mucuna Bean."; 2010. Abstract

Mucuna (Mucuna pruriens) is a legume with high but unexploited potential for food and soil fertility improvement. Use of the seed as food is limited by the hard-to-cook defect and the presence of several antinutritional factors notably the non-protein amino acid, 3, 4 ...

Wanjekeche E;, Imungi JK;, Karuri EG. "Effect of Soaking on the Cookability and Nutritional Quality of Mucuna Bean."; 2010. Abstract

Mucuna (Mucuna pruriens) is a legume with high but unexploited potential for food and soil fertility improvement. Use of the seed as food is limited by the hard-to-cook defect and the presence of several antinutritional factors notably the non-protein amino acid, 3, 4 .

Wanjare, J. & Ojwang P(2016). "Behavioral Factors and Financial Decisions by Traders in Kibuye Market, Kisumu City, Kenya." Online Journal of Social Sciences Research, ISSN 2277-0844. 2016;Vol 5, 29 - 39.
Wanjare, J. OOP & O. "Organizational Characteristics that are Antecedents to Organizational Learning: A Case of Maseno University, Kenya." An International Journal of Arts and Humanities. 2012;Vol 1:305-321.

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