McLigeyo SO.Gromerular diseases in Kenya-another look at diseases characterised by nephrotic proteinura. Afr J Health Sci. 1994 Nov;1(4):185-190.

Citation:
O PROFMCLIGEYOSETH. "McLigeyo SO.Gromerular diseases in Kenya-another look at diseases characterised by nephrotic proteinura. Afr J Health Sci. 1994 Nov;1(4):185-190.". In: African Journal of Medical Practice 1(5):129-132, 1994. University of Nairobi.; 1994.

Abstract:

Renal biopsies were evaluated in 422 patients with nephrotic syndrome at the Kenyatta National Hospital between 1982 and 1993. Three hundred and fifty five (84.1%) of the patients were less than 30 years old (range: 7 months to 66 years; mean=SD: 28.4 - 9.2 years). The commonest histological lesions were mesangial proliferative glomerulonephritis (25.1%), minimal change nephropathy (17.5%) and focal segmental glomerulosclerosis (15.2%). Poststreptococcal aetiology was implicated in diffuse proliferative glomerulonephritis while use of skin lightening cosmetics appeared to play a role in the aetiology of minimal change nephrophathy in females. No aetiological role was apparent for hepatitis B virus, human immunodeficiency virus, malarial or schistosomal infection. All patients with minimal change nephropathy, focal segmental glomerulosclerosis and mesangial proliferative glomerulonephritis were treated with steroids and/or cytotoxics with a variable response.

Notes:

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