Synthesis of aminoalkyl vernolamides from vernonia oil at varied conditions

Citation:
Mbugua MN. "Synthesis of aminoalkyl vernolamides from vernonia oil at varied conditions." Journal of Kenya Chemical Society. 2006;3(1):1-8.

Abstract:

The oil extracted from the seeds of Vernonia galamensis ssp. nairobensis was reacted with 1,6-diaminohexane and 1,8-diaminooctane using a 1:3 molar ratio of vernonia oil to amine to give the corresponding vernolamides. Varied temperatures and solvents were applied. The vernolamides exhibited antibacterial activity against gram-positive (Bacillus subtilis) and on gram-negative (Escherichia coli) bacteria. The vernolamides did not show any antifungal activity.

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