Peripheral Neuropathy among Patients with Type Diabetes mellitus attending Kenyatta National Hospital

Citation:
NJAMBI DRCHEGEMARGARET. "Peripheral Neuropathy among Patients with Type Diabetes mellitus attending Kenyatta National Hospital."; 2012.

Abstract:

2nd East Africa Neuroscience Conference, 18-19 June 2012, Nairobi,
Kenya
Peripheral Neuropathy among Patients with Type Diabetes mellitus attending
Kenyatta National Hospital
Stephen Kainga1
,2, Margaret Chegel, Miriam Wagoro\ Samuel Kiman!' ~
'University of Nairobi and 2Ministry of Medical Services, Government of Kenya.
Diabetes mellitus (DM) has become the epidemic of the 21st century with the
poorest nations bearing the greatest burden. DM affects both central and peripheral
nerves causing dysfunctional sensory activity with peripheral neuropathy (PN)
being the most common complication. Peripheral neuropathy has been associated
with lower limbs pain and ulceration among diabetic patients resulting to increased
morbidity, disability and reduced quality of life. Objective: We determined the
prevalence ofPN among patients with type 2 DM attending Kenyatta National
Hospital. Methods: We carried out descriptive cross-sectional study involving 147
patients with DM attending the KNH. Clinical history and physical findings were
captured using questionnaires and a focused physical examination. Data was
analyzed using SPSS software (version 17). Statistical significance was set at a cut
off value of 0.05. Results: Based on history and signs of peripheral numbness and
pain, 60 (41.1 %) participants with DM had PN. Peripheral neuropathy was
significantly associated with coexistence of DM and hypertension. Furthermore,
the duration of DM, participants' age and difficulties in healthcare financing were
significantly associated with PN. However, our study did not elicit any association
between smoking, alcohol consumption and prevalence of PN among the
participants. Conclusion: Our findings underscore the role ofDM on the
occurrence ofPN, the main cause of morbidity, disability, and reduced quality of
life among patients. Early diagnosis and adequate management of DM can
significantly reduce diabetic neuropathy and should be incorporated

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