PROF. ABUGA, KENNEDY OMONDI
BPharm (UoN), MPharm (KUL), PhD (UoN)
Department of Pharmaceutical Chemistry, School of Pharmacy, Kenyatta National Hospital Campus, off Hospital road.+254202314294; koabuga@uonbi.ac.ke
Department of Pharmaceutical Chemistry, School of Pharmacy, Kenyatta National Hospital Campus, off Hospital road.+254202314294; koabuga@uonbi.ac.ke
The aerial parts of Nicandra physaloides plant collected from Kenyatta National Hospital grounds were dried and subjected to acid-base extraction and partitioned to obtain alkaloidal and non-alkaloidal extracts. The non-alkaloidal extract yielded three compounds; withanicandrin, β-sitosterol and stigmasterol after column chromatography. Withanicandrin exhibited antifungal activity against Saccharomyces cerevisiae and Candida albicans but lacked antibacterial activity.