Phytochemical and Anthelmintic Study of the Root Bark of Teclea Trichocarpa, Engl. (Rutaceae)

Citation:
Muema SM, Abuga KO, Yenesew A, Thoithi GN. "Phytochemical and Anthelmintic Study of the Root Bark of Teclea Trichocarpa, Engl. (Rutaceae)." East Cent. Afr. J. Pharm.. 2014;17(2):44-47.

Abstract:

The root bark of Teclea trichocarpa exhibited anthelmintic activity against egg hatching and larval development of sheep nematodes (Strongyloides). Three compounds, namely lupeol, melicopicine and 6-methoxytecleanthine were isolated from the dichloromethane-methanol (50:50) extract of the plant. Melicopicine and 6-methoxytecleanthine exhibited mild anthelmintic activity. The present study lends scientific credence to the traditional use of Teclea trichocarpa in the treatment of human helminth infections.

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