Bio

Publications


2010

Mwangangi, LEM, Juma R, Scott DK, Nyamu DG, Kuria KAM.  2010.  Risk factors, management and outcomes of adverse drug reactions in adult patients on antiretrovirals at Kenyatta National Hospital, Nairobi. Abstract

Antiretrovirals have been associated with serious adverse drug reactions. Several factors have been suggested as independent risk factors for their development. Identification of these factors may help in prevention and management of the adverse drug reactions.Current standard regimens in resource-limited countries are associated with an increased risk of adverse drug reactions. Almost half of adverse reactions are managed by addition of a non-anti-retroviral drug alone but 41% necessitated a change of anti-retrovirals.

2009

Mwangangi, LEM, Juma R, Scott DK, Nyamu DG, Kuria KAM.  2009.  Prevalence of adverse drug reactions in adult patients on anti-retrovirals at Kenyatta National Hospital, comprehensive care centre. Abstract

There has been an increased access to anti-retrovirals in resource constrained settings. However, few studies have addressed the area of adverse drug reactions in these settings.This study indicates a high prevalence of adverse drug reactions among HIV/AIDS patients on anti-retroviral therapy at Kenyatta National Hospital, Comprehensive Care Centre.

2006

MUTUIRI, DRBURURIAJOHN, NDIRANGU DKARIMIPETER, MAHINDRA DRMARUSHITAL, MOSES DRKURIAKIMANIARTHUR.  2006.  P.N. Karimi, S.M. Maru, J.M. Bururia, K.A.M. Kuria and P.A. Odhiambo (2006). Prevalence and Antimicrobial Susceptibility of Staphylococcus aureus at the Kenyatta National Hospital, Nairobi. East Centr. Afr. J. Pharm. Sci.9:71-73.. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

2004

Ndungu, TK, Maru SM, Kuria KAM, Karimi PN, Bururia JM.  2004.  Prescription audit carried out at the pharmacy practice centre of the University of Nairobi between June and November 2004. Abstract

A retrospective descriptive study was carried out from June to November 2004 in a retail pharmacy situated at the School of Pharmacy, University of Nairobi within the Kenyatta National Hospital complex. The objective was to evaluate prescribing habits and to determine the frequency of prescribing of commonly used drug classes in a hospital. The average number of drugs per prescription was 2.20  1.16. The prevalence of prescribing was 28.6% anti-infective drugs, 21.1% musculoskeletal agents, 16.6% respiratory system drugs, 8.1% cardiovascular system drugs, 7.2% central nervous system drugs, 7.1% gastrointestinal system drugs, 4.3% minerals and vitamins, 2.1% ear, nose and throat drugs, 1.1% endocrine drugs, 2% skin preparations, 0.9% anticancer drugs and 0.74% eye preparations. The prescribing habits evaluated were compared to the legal requirements in Kenya and to recommended international practice. The information gathered may serve as a basis for rational use of drugs.

2003

MOSES, DRKURIAKIMANIARTHUR.  2003.  D. K. Kariuki, J.O. Miaron, A.K. Kuria, J. Mugweru and A. Mwaura (2003). Synergistic Effects of �� -Cypermethrin and Dimethoate against Insect Pests. The East and Central African Journal of Pharmaceutical Sciences, 6, 64-68.. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

2002

MOSES, DRKURIAKIMANIARTHUR.  2002.  K.A.M. Kuria, G. Muriuki, I. Kibwage, W. Masengo, A.M. Mwaura, P. De Witte, G. M Laekman. Cytotoxic activity of Ajuga remota. Submitted in February 2002 for publication in Fitoterapia.. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
MOSES, DRKURIAKIMANIARTHUR.  2002.  Kimani A.M.Kuria, Hezekiah Chepkwony, Cindy Govaerts, Eugene Roets, Roger Busson, Peter De Witte, Istvan Zupko, Georges Hoornaert, Ludo Quirynen, Louise Maes, Leen Janssens, Jos Hoogmartens and Gert Laekeman (2002). The Antimalarial Activity of Isolates f. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
MOSES, DRKURIAKIMANIARTHUR.  2002.  K.Njunge, Gichuru Muriuki, J.W. Mwangi and K.A.M. Kuria (2002). Analgesic and Antipyretic Effects of Myrica salicifolia (Myricaceae).Phytother. Res. 16, S73 - S74. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

2001

MOSES, DRKURIAKIMANIARTHUR.  2001.  K.A.M. Kuria, S. De Coster, G. Muriuki, W. Masengo, I. Kibwage, J. Hoogmartens, G.M. Laekeman (2001). Antimalarial activity of Ajuga remota Benth (Labiatae) and Caesalpinia volkensii Harms (Caesalpiniaceae): in vitro confirmation of ethnopharmacological u. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract

A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

MOSES, DRKURIAKIMANIARTHUR.  2001.  K.A.M. Kuria, M. De Proft, W.Masengo,I.Kibwage, L.Quirynen, L.Maes, L.Janssen, J.Hoogmartens and G.M. Laekeman (2001). Cultivating the African plant Ajuga remota in Belgium and confirming its biological activity against Plasmodium falciparum. Zeitschrift . East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
MOSES, DRKURIAKIMANIARTHUR.  2001.  Arthur Kimani Kuria. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

1987

MOSES, DRKURIAKIMANIARTHUR.  1987.  A.N. Guantai, J.W. Mwangi, Gichuru Muriuki and K.A.M. Kuria (1987). Effects of the active constituents of Catha edulis on the neuromuscular junction. Neuropharmacology 26(5), 401 - 405.. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
MOSES, DRKURIAKIMANIARTHUR.  1987.  A.N. Guantai, J.W. Mwangi, Gichuru Muriuki and K.A.M. Kuria (1987). Effects of the active constituents of Catha edulis on the neuromuscular junction. Neuropharmacology 26(5), 401 - 405.. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

1984

MOSES, DRKURIAKIMANIARTHUR.  1984.  K.A.M. Kuria and G. Muriuki (1984). A New Cardiotonic Agent from Ajuga Remota Benth (Labiatae). East African Med. J. 61, 533-538 (July 1984).. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

1978

MOSES, DRKURIAKIMANIARTHUR.  1978.  Rees JE,. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

1976

MOSES, DRKURIAKIMANIARTHUR.  1976.  K.A.M. Kuria (1976). Ajuga remota Benth. Isolation and characterisation of the herb's bitter principle. M.Sc.(Pharmacy) thesis.. East Centr. Afr. J. Pharm. Sci.. : EAMJ Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.

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