The main intention of this thesis is to establish design principles and evolve a design for Kayole District Centre within the North Eastern part of Nairobi city region. The design of Kayole District Centre should be seen as an evolution of design principles which can also be applied in designing other district centres now that decentralization of Nairobi City Centre is imminent. The first chapter is a discussion of one of the major design determinants; the context within which Kayole district centre will grow. In this chapter the geographical placement of Kayole District Centre in respect to other surrounding urban centres has been analysed in an attempt to establish the catchment population it will serve at various strategic years. The first chapter also shows the correlation between the catchment population arid the planned infrastructure. In this way it has been established that the planned infrastructure can support both Kayole District Centre and its catchment population for various strategic years. Chapters two and three are case studies of two suburban centres, Westlands and Eastleigh. The intention in these two chapters is a critical study, in an attempt to discern the forces behind the functional zoning movement patterns, structure, and urban form of the two centres. Westlands and Eastleigh have been chosen because they cater for different income Chapter five is the design of Kayole District groups and evolved from different urban cultures. Thus Westlands serves a high income group and is western in outlook. Eastleigh on the other hand serves a low income group and was an Asian settlement at its inception. In their nature the two case studies constitute a spectrum of the urban reality in Nairobi City region. The design determinants discerned in chapters two and three have been embodied in chapter four which is a conclusion of the case studies. In the fourth chapter as in the design, the more sensory determinants have been given greater emphasis. Centre. As far as has been possible, the design incorporates what has been learned in the case studies. The centre is in two sectors. The main sector constitutes a majority of commercial, residential, social and administrative facilities. This sector is complete in itself and is the only sector, that the design goes into detail. The second sector to the East has some major institutions and future extensions of commercial and residential activities of the Centre. The institutions in this sector are so specialized that it is beyond the scope of this thesis to design them to any detail. Only the required amounts of land has been set aside. Although the future commercial and residential activities have pot been designed to any detail, the design principles used in the design of the first sector, to the West should apply.