Foetal outcomes in women with pregnancy related acute kidney injury in a referral facility in Kenya.

Citation:
JM K, JK K, AO W, Q Z. "Foetal outcomes in women with pregnancy related acute kidney injury in a referral facility in Kenya. ." IOSR Journal of Dental and Medical Sciences (IOSR-JDMS). 2019;18(11):52-56.

Abstract:

Background: Pregnancy related acute kidney injury (PRAKI) is an obstetric complication,which can occur at
any stage of pregnancy and in postpartum,often associated with significant adverse foetaloutcomes.
Objective:To determine foetal outcomes among patients with PRAKI at Kenyatta National Hospital (KNH),
Kenya.
Methods:We carried out a descriptive study on pregnant women with gestation age equal or above 28 weeks
and postpartum women within six weeks after deliverywho were admitted in labour ward or the post-natal
wards at KNH. Study commenced following approval by the KNH- University of Nairobi Ethics and Research
Committee. Data was obtained from both the patient and the medical records. Participants were followed up
until discharge orfor a maximum of two weeks. Patient management was at the discretion of attending clinician.
Results: ATotalof 66participants with a mean age of 28years and peak age between 26-30 years were enrolled
into the study out of 2068 admissions. The prevalence of PRAKI was 3.2%. Sixty (91%) participants gave birth
during the follow-up period and sixremained pregnant pastthe two weeks after enrollment. Average gestation
age at delivery was 35 weeks. Life infant were 43(71.7%) and fresh still births were 17(28.3%). Preterm births
were the majority33(55%),of whom 23were life infants and 10 were fresh still births.Comparing between
participants and women without PRAKI, the ratio of fresh still births was 1:4 while the ratio of fresh still births
among women without PRAKI was 1:23deliveries.
Conclusion:We demonstrate anaverage gestation age of 35 weeks and a six (6) fold increase in fresh still births
among women with pregnancy related acute kidney injury at KNH.
Key Words: PRAKI, KNH, Gestation age, Fresh still births, Kenya

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