Bioavailability of cobalt, Zinc and Selenium and Anthelmintic effects of fortified and non fortified Albendazole in Sheep. J.M.Nguta; J.M.Mbaria

Citation:
NGUTA DRJOSEPHMWANZIA. "Bioavailability of cobalt, Zinc and Selenium and Anthelmintic effects of fortified and non fortified Albendazole in Sheep. J.M.Nguta; J.M.Mbaria.". In: The Kenya Veterinarian, Volume 35, Issue 1, 2011. The Kenya Veterinary Association; Submitted.

Abstract:

Abstract: The present study was carried out to compare the use of liver and plasma analysis as methods of assessing the status of cobalt, zinc and selenium in sheep, and also to assess the anthelmintic efficacy of fortified and non-fortified albendazole preparations. plasma and liver samples were collected in duplicate from fourteen sheep aged nine to twelve months. Plasma samples were collected on days 0, 7, 14, 21 and 28 and liver samples  on days 0, 14 and 28 post treatment, upon sacrifice of the study animals. Various trace elements were isolated from the organic matrix by wet oxidation for mineral analysis using atomic absorption spectrophotometry. data was statistically analysed using repeated measurement test. Significance was noted at p < 0.05. Both the fortified albendazole and non fortified albendazole cleared all the worms in the treated sheep by day 14 post treatment. All the trace elements were shown to be more bioavailable in the liver and plasma of fortified albendazole (Group B) treated sheep compared to the non-fortified albendazole (Group A) treated sheep. The current study has shown that the liver is a better indicator of cobalt, zinc and selenium status in sheep compared to plasma.
Key words: Plasma; Liver; Cobalt; Zinc and Selenium

Notes:

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