Ochanda,J.O., Oduor, EAC.,Mumcuoglu,K.Y., Imbuga,M.O, Oduol,V.O BenYakir, and Galun, R. Characterization of body louse midgut proteins. Proceedings of the First Meeting of Federation of African Society of Biochemistry and Molecular Biology. Page (305-314)

Citation:
O. PROFOCHANDAJAMES. "Ochanda,J.O., Oduor, EAC.,Mumcuoglu,K.Y., Imbuga,M.O, Oduol,V.O BenYakir, and Galun, R. Characterization of body louse midgut proteins. Proceedings of the First Meeting of Federation of African Society of Biochemistry and Molecular Biology. Page (305-314).". In: Proceedings of the fifth international in situ and on . East African Medical Journal; 1998.

Abstract:

OBJECTIVE: Screening and biochemical characterisation of trypanosome-lysing factor (trypanolysin) from non-vector insect, Schistocerca gregaria. DESIGN: Laboratory based experiment. SETTING: Department of Biochemistry, University of Nairobi. RESULTS: Lysis of isolated trypanosomes was demonstrated with midgut homogenates of natural vector Glossina morsitans centralis as well in non-vector insects. The highest trypanolytic activity was observed in midgut homogenate of the desert locust. Schistocerca gregaria followed by the cockroach, Periplaneta americana (L). Further studies on the S. gregaria trypanolytic factor showed its proteinaceous nature due to its sensitivity to temperatures above 40 degrees C and to proteases. Additionally, the factor showed lectin-like properties since the activity was blocked by D-glucosamine. CONCLUSION: The trypanolytic factor has the potential of being used to modulate tsetse fly vectorial capacity.

Notes:

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