R. Scott McClelland, Jared M. Baeten, Barbra A. Richardson, Ludo Lavreys, Sandra Emery, Kishorchandra Mandaliya, Jeckoniah O. Ndinya-Achola and Julie Overbaugh. A Comparison of Genital HIV-1 Shedding and Sexual Risk Behaviour Among Kenyan Women Based on E

Citation:
O. PROFNDINYA-ACHOLAJ. "R. Scott McClelland, Jared M. Baeten, Barbra A. Richardson, Ludo Lavreys, Sandra Emery, Kishorchandra Mandaliya, Jeckoniah O. Ndinya-Achola and Julie Overbaugh. A Comparison of Genital HIV-1 Shedding and Sexual Risk Behaviour Among Kenyan Women Based on E.". In: J. Acquir Immune Defic Syndr, April 2006, Vol. 41, No. 5. IBIMA Publishing; 2006.

Abstract:

We conducted a prospective study among women in Mombasa, Kenya, to determine whether Trichomonas vaginalis infection was associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) infection. At monthly follow-up visits, laboratory screening for HIV-1 and genital tract infections was conducted. Among 1335 HIV-1-seronegative women monitored for a median of 566 days, there were 806 incident T. vaginalis infections (23.6/100 person-years), and 265 women seroconverted to HIV-1 (7.7/100 person-years). Trichomoniasis was associated with a 1.52-fold (95% confidence interval, 1.04-2.24-fold) increased risk of HIV-1 acquisition after adjustment for potential confounding factors. Treatment and prevention of T. vaginalis infection could reduce HIV-1 risk in women.

Notes:

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