SYNTHETIC TRANSFORMATION OF SELECTED FLAVONOIDS

Citation:
Mwaniki JM. "SYNTHETIC TRANSFORMATION OF SELECTED FLAVONOIDS.". In: 12th NAPRECA SYMPOSIUM, Hotel Africana, Kampala Uganda, Tuesday 24th July 2007. Napreca; 2007.

Abstract:

Chalcones, flavanones and other flavonoids have been shown to have varied anti-plasmodium activity. In this work, chalcones were synthesized from corresponding flavanones  extracted from Senecio roseiflorus, Erythina abysinica and Polygonum senegalense, using conventional organic reagents and green chemistry approach.Dihydrochalcones were converted to homoisoflavones using the Kostanecki reaction. Characterization and bioassay on the synthetic derivatives was also undertaken.

Notes:

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