The root and stem bark of Erythrina species are widely used in traditional medicine for the treatment of microbial infections: In our interest on the phytochemistry of Erythrina species of Kenya, we have isolated several flavonoids, including new flavanones (eg. 1) and isoflav-3-enes (eg 2) from Erythrina burttii; isoflavones (eg. 3) and isoflavanones (eg. '1) from Erythrina sac/euxii. Some of these compounds show antibacterial, anti-fimgal, anti-malarial and anti-oxidant activities. The structure elucidation and biological activities of some of these compounds will be discussed.