Publications


1994

NJUGUNA, DRMBURUJOHN.  1994.  J.N. Mburu, M.S. Badamana. and J.M.Z. Kamau. Faecal and Urinary Losses of Nitrogen in Cobalt-Deficient Small East African Goats. Indian Journal of Animal Science 64 (1994), 1264-1267.. Insitute for Communication Research, Stanford University.. : au-ibar Abstract
Two groups of 6 rats each received subcutaneous injections of 2.3 mg/kg or 5.0 mg/kg of quinuronium, respectively, on two consecutive days, while 5 rats injected with physiological saline served as controls. Clinical signs of muscular tremors, jumps, enlarged and hyperemic eyeballs, lacrimation, depression and anorexia were observed following administration of quinuronium. One rat receiving 5 mg/kg died before termination of the study. When killed 48 h after the first injection, the quinuronium-treated rats had a higher liver weight/body weight ratio compared to the controls. Quinuronium resulted in hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH). The present findings suggest that glutathione depletion does not seem to be involved in quinuronium hepatotoxicity
NJUGUNA, DRMBURUJOHN.  1994.  J.N. Mburu, J.M.Z. Kamau and M.S. Badamana and P.N.Mbugua Use of Serum Vitamin B12 in Diagnosis of Cobalt Deficiency in Small East African Goats. Bull. Anim. Hlth.Prod. Afr. 42 (1994), 141-146.. Insitute for Communication Research, Stanford University.. : au-ibar Abstract
Two groups of 6 rats each received subcutaneous injections of 2.3 mg/kg or 5.0 mg/kg of quinuronium, respectively, on two consecutive days, while 5 rats injected with physiological saline served as controls. Clinical signs of muscular tremors, jumps, enlarged and hyperemic eyeballs, lacrimation, depression and anorexia were observed following administration of quinuronium. One rat receiving 5 mg/kg died before termination of the study. When killed 48 h after the first injection, the quinuronium-treated rats had a higher liver weight/body weight ratio compared to the controls. Quinuronium resulted in hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH). The present findings suggest that glutathione depletion does not seem to be involved in quinuronium hepatotoxicity
NJUGUNA, DRMBURUJOHN.  1994.  J.N. Mburu, J.M.Z. Kamau and M.S. Badamana. Thyroid Hormones and Metabolic Rate During Induction of Vitamin B12 Deficiency in Goats. New Zealand Veterinary Journal 42 (1994), 187-189.. Insitute for Communication Research, Stanford University.. : au-ibar Abstract
Two groups of 6 rats each received subcutaneous injections of 2.3 mg/kg or 5.0 mg/kg of quinuronium, respectively, on two consecutive days, while 5 rats injected with physiological saline served as controls. Clinical signs of muscular tremors, jumps, enlarged and hyperemic eyeballs, lacrimation, depression and anorexia were observed following administration of quinuronium. One rat receiving 5 mg/kg died before termination of the study. When killed 48 h after the first injection, the quinuronium-treated rats had a higher liver weight/body weight ratio compared to the controls. Quinuronium resulted in hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH). The present findings suggest that glutathione depletion does not seem to be involved in quinuronium hepatotoxicity

1993

NJUGUNA, DRMBURUJOHN.  1993.  J.N. Mburu, J.M.Z. Kamau and M.S. Badamana. Changes in Serum Levels of Vitamin B12, Feed Intake, Liveweight and Hematological parameters in Cobalt Deficient Small East African Goats. Internat. J. Vit. Nutr.Res.63 (1993), 135-139.. Insitute for Communication Research, Stanford University.. : au-ibar Abstract
Two groups of 6 rats each received subcutaneous injections of 2.3 mg/kg or 5.0 mg/kg of quinuronium, respectively, on two consecutive days, while 5 rats injected with physiological saline served as controls. Clinical signs of muscular tremors, jumps, enlarged and hyperemic eyeballs, lacrimation, depression and anorexia were observed following administration of quinuronium. One rat receiving 5 mg/kg died before termination of the study. When killed 48 h after the first injection, the quinuronium-treated rats had a higher liver weight/body weight ratio compared to the controls. Quinuronium resulted in hepatic centrilobular fatty degeneration, but no depletion of hepatic glutathione (GSH). The present findings suggest that glutathione depletion does not seem to be involved in quinuronium hepatotoxicity

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