7a-O-methyldequelol, a modified rotenoid with an open ring-C from the roots of derris trifolianta Phytochemistry, Vol. 66, 653-657.

Citation:
DR. KABARU JACQUESM. "7a-O-methyldequelol, a modified rotenoid with an open ring-C from the roots of derris trifolianta Phytochemistry, Vol. 66, 653-657.". In: Massachusetts. CABI. Pp 209. African Meteorological Society; 2005.

Abstract:

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The crude methanol extract of the seeds of Derris trifoliata showed potent and dose dependent larvicidal activity against the 2nd instar larvae of Aedes aegypti. From this extract two unusual rotenoid derivatives, a rotenoloid (named 7a-O-methyl-12a-hydroxydeguelol) and a spirohomooxarotenoid (named spiro-13-homo-13-oxaelliptone), were isolated and characterised. In addition a rare natural chromanone (6,7-dimethoxy-4-chromanone) and the known rotenoids rotenone, tephrosin and dehydrodeguelin were identified. The structures were assigned on the basis of spectroscopic evidence. The larvicidal activity of the crude extract is mainly due to rotenone.

Notes:

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