Githang'a JN, Dave P. Bone marrow examination at a paediatric hospital in Kenya. East Afr Med J. 2001 Jul;78(7 Suppl):S37-9.

Citation:
N DRGITHANGAJESSIE. "Githang'a JN, Dave P. Bone marrow examination at a paediatric hospital in Kenya. East Afr Med J. 2001 Jul;78(7 Suppl):S37-9.". In: Pharmacogenetics. 2001 Apr;11(3):217-21. Douglas McLean Publishing; 2001.

Abstract:

OBJECTIVE: To investigate the main indications for, and common conditions found in bone marrow examinations (BME) of children. METHODS: This was a retrospective study from September 1, 1993 to September 3 1998. All bone marrow aspirate and trephine biopsy results were retrieved. The clinical data provided by clinicians were also noted. RESULTS: A total of 97 BME were recorded from patients aged two months to 13 years. The peak ages for BME were six to eight years (24% of patients). The more frequent indications for BME were unexplained anaemia found in 26% request forms, investigation for solid tumours (10%) and lymphoma (10%) and remission assessment after treatment for leukaemia (26%). The main findings were malignancy (27%) with leukaemia being commonest (ALL) 16% of patients and acute myeloblastic leukaemia (5%). Haematinic deficiency was seen in 12.7% of cases with iron deficiency being the commonest. There were some notable differences and similarities in the study as compared to a similar one performed at a local referral hospital. CONCLUSION: The importance of BME as a crucial investigational tool in the management of patients is underscored. Interpretation is more meaningful when the haematologist has adequate clinical data.

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