J. M. Mbaria, T. E. Maitho and D. J. Muchiri (1991). Effects of pyrethrins on Haemonchus contortus in vitro.

Citation:
MUCUNU DRMBARIAJ. "J. M. Mbaria, T. E. Maitho and D. J. Muchiri (1991). Effects of pyrethrins on Haemonchus contortus in vitro.". In: Proceedings of the first inter-university pharmacology and Toxicology subject meeting held in Arusha, Tanzania from 24th-28th September, 1991. Kluwer Academic Publishers; 1991.

Abstract:

ABSTRACT: The efficacies of pyrethrum marc and of albendazole against experimental sheep gastrointestinal nematode infection were compared. Sheep were infected orally with 10000 larvae (Haemonchus spp. (60.1%), Oesophagostomum spp. (13.9%), Trichostrongylus spp. (13.2%), Cooperia spp. (8.3%), Nematodirus spp. (3.5%), Strongyloides spp. (0.8%) and Ostertagia spp. (0.2%)). Faecal egg count reduction in albendazole-treated sheep was 100% by day 4 following treatment, compared to 37.03%, 31.3%, 38.9% and 51.8% on days 4, 6, 8 and 10 in pyrethrum marc-treated sheep. These reductions were statistically significant on days 8 and 10 post-treatment (p<0.05). The potential for using pyrethrins for helminth treatment is discussed.

Notes:

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