Bio

DR ISACC MAPENAY

Dr. I.M Ole Mapenay is a lecturer in Pharmacology and Toxicology in the academic department of Public Health, Pharmacology and Toxicology. He obtained his MSc (Pharmacology and Toxicology) and PhD (Pharmacology) from the University of Nairobi in 1994 and 2006 respectively. He has a teaching experience of over 13 years at both undergraduate and postgraduate level. He has supervised several MSc and PhD candidates to completion. Dr. Mapenay has published over 12 papers in peer reviewed academic Journals of international repute.  Dr.

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Publications


2005

OLE, DRMAPENAYISAACM.  2005.  The performance of Orma Boran and Maasai Zebu crossbreeds in. journal. : EAEP Abstract
Studies on the trypanotolerance of Orma Boran X Maasai Zebu (Orma Zebu) crossbred cattle (F1 progeny) and pure-bred Maasai Zebu contemporaries were carried out in Nguruman, south western Kenya. The two groups were monitored from birth for a period of 2 years. The incidence of trypanosomosis, parasitaemia, packed cell volume (PCV), body mass and average daily mass gain were monitored. During the study period, overall trypanosomosis incidence was low (3%).The crossbred cattle had a higher incidence of infection (61% vs 39%). The mean PCV and the mean mass gain for the crossbred cattle was higher than that of the Maasai Zebu. The mean calf body mass at weaning (8 months) for the Orma Zebu and Maasai Zebu was 72 kg and 64 kg, respectively, while at 18 months of age their mean body mass was 164 kg and 123 kg, respectively. During the rainy season significant differences in average daily mass gains were noted (p<0.05). The superior mass gain of the Orma Zebu observed during the rainy season, despite higher infection rates, indicate an enhanced trypanotolerance. Moreover, the better performance of the Orma Zebu is an attribute that could be exploited in the adoption of the trypanotolerance genotype, as a sustainable trypanosomosis control strategy.   Keywords: Cattle, productivity, Maasai Zebu, Orma Boran, Orma Zebu, trypanotolerance

2004

OLE, DRMAPENAYISAACM.  2004.  Maasai ethnoveterinary: an avenue for anthelmintic biosprospecting.. Proc. Fac. Vet. Med. Scientific conf. Kenya Veterinarian Vol. 6. : EAEP Abstract
Studies on the trypanotolerance of Orma Boran X Maasai Zebu (Orma Zebu) crossbred cattle (F1 progeny) and pure-bred Maasai Zebu contemporaries were carried out in Nguruman, south western Kenya. The two groups were monitored from birth for a period of 2 years. The incidence of trypanosomosis, parasitaemia, packed cell volume (PCV), body mass and average daily mass gain were monitored. During the study period, overall trypanosomosis incidence was low (3%).The crossbred cattle had a higher incidence of infection (61% vs 39%). The mean PCV and the mean mass gain for the crossbred cattle was higher than that of the Maasai Zebu. The mean calf body mass at weaning (8 months) for the Orma Zebu and Maasai Zebu was 72 kg and 64 kg, respectively, while at 18 months of age their mean body mass was 164 kg and 123 kg, respectively. During the rainy season significant differences in average daily mass gains were noted (p<0.05). The superior mass gain of the Orma Zebu observed during the rainy season, despite higher infection rates, indicate an enhanced trypanotolerance. Moreover, the better performance of the Orma Zebu is an attribute that could be exploited in the adoption of the trypanotolerance genotype, as a sustainable trypanosomosis control strategy.   Keywords: Cattle, productivity, Maasai Zebu, Orma Boran, Orma Zebu, trypanotolerance

2002

OLE, DRMAPENAYISAACM.  2002.  TRYPANOSOMOSIS AND HELMINTHOSIS IN CAMELS: COMPARISON OF RAN. journal. : EAEP

2000

OLE, DRMAPENAYISAACM.  2000.  Prevalence of trypanosomosis in camel calves: A pilot study. journal. : EAEP

1999

OLE, DRMAPENAYISAACM.  1999.  Preliminary analysis on the performance of the Orma bull, a trypanotolerant breed at Nguruman.. Proceedings of the Commonwealth Veterinary Association for East, Central and Southern Africa held on 20th . : EAEP

1998

OLE, DRMAPENAYISAACM.  1998.  Adaptability of Maasai Zebu/Orma boran calves raised in a trypanosomosis endemic region.. Proceedings of the 7th Ketri Annual Internal Scientific Review on 22nd - 26th June 1998, No. 66 Pp 21-22.. : EAEP
OLE, DRMAPENAYISAACM.  1998.  Trypanocidal drug use in selected trypanosomes endemic areas in Kenya: a survey.. Proceedings of the 7th Ketri Annual Internal Scientific Review on 22nd - 26th June 1998, No. 66 Pp 28.. : EAEP

1997

Mitema, ES, Ole-Mapenay IM.  1997.  Efficacy of doxycycline in a goat model of Pasteurella pneumonia: research communication. Abstract

The clinical efficacy of doxycycline (Doxycen(R), Cenavisa, Spain), a long-acting preparation, was evaluated for treatment of Pasteurella haemolytica infection in 6 goats. One goat was not infected and served as a control. The disease was induced by intratracheal inoculation of 107 to 109 cfu of P. haemolytica. Confirmation of respiratory disease was based on evidence of appropriate clinical signs. Before and after initiation of doxycycline treatment on day 10, each goat was examined daily. Three clinical responses to doxycycline treatment were noted. Mean rectal temperatures decreased from 40.1 oC to normal, while mean respiratory rate decreased from the pre-treatment value of 32 to 27/min after 4 days. Other clinical signs associated with pneumonia resolved within 3-5 days post treatment. In addition the minimum inhibitory concentration of DOTC for the P. haemolytica isolate was found to be <0.5 mg/mℓ. The present study indicates that DOTC may be a useful antimicrobial agent in the treatment of caprine pasteurellosis.

MITEMA, PROFSEO, OLE DRMAPENAYISAACM, ELIAS PROFMAITHOT.  1997.  ASPECTS OF THE PHARMACOKINETICS OF DOXYCYCLINE GIVEN TO HEAL. journal. : EAEP
OLE, DRMAPENAYISAACM, MITEMA PROFSEO.  1997.  Eficacy of doxycycline in goats. journal. : EAEP
OLE, DRMAPENAYISAACM, MITEMA PROFSEO.  1997.  SOME PHARMACOKINETIC PARAMETERS OF DOXYCYCLINE IN EAST AFRIC. journal. : EAEP

1995

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