Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia

Citation:
Mwirigi M, Nkando I, Olum M, Attah-Poku S, Ochanda H, Berberov E, Potter A, Gerdts V, Perez-Casal J, Wesonga H, Soi R, Naessens J. "Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia." Veterinary Immunology and Immunopathology. 2016;178:64-69.

Abstract:

Abstract Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease
caused by Mycoplasma mycoides subsp. mycoides (Mmm) which is widespread in Africa.
The capsule polysaccharide (CPS) of Mmm is one of the few identified virulence
determinants. In a previous study, immunization of mice against CPS generated antibodies,
but they were not able to prevent multiplication of Mmm in this model animal. However, mice
cannot be considered as a suitable animal model, as Mmm does not induce pathology in ...

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