PROF. JUMA FRANCIS D
MBChB (Nairobi), Ph.D (London)
Physical Address: 19676 00100 Nairobi GPO
2724092, 3874527
Email: fdjuma@uonbi.ac.ke
Physical Address: 19676 00100 Nairobi GPO
2724092, 3874527
Email: fdjuma@uonbi.ac.ke
Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), isouvaretin (5), diuvaretin (6), and uvangoletin (7). The structural elucidation of compounds 1 and 2 in spectroscopic studies is described. C-Benzylated dihydrochalcones, especially 1, 2, 4, and 6, showed considerable cytotoxicity toward human promyelocytic leukemia HL-60 cells.
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