This paper is based on a condition assessment survey of a historic house and museum, Karen Blixen. The aim was to assess the potential risks that historic buildings are exposed to through external and internal forms of aggression. The study revealed that the building suffers structural problems that need urgent attention if it is to continue serving an important role as part of the Kenyan cultural heritage. It was further observed that some basic housekeeping policies should be instituted in order to control the rate of deterioration on the collections. This paper raises a series of conservation issues and makes recommendations that should be discussed and worked out in a collaborative manner by the various stakeholders.