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Conference Paper
WAKONYU DRKANJAL, ELIAS PROFMAITHOT. "Levels of organochlorine Pesticide residues in milk of Urban Mothers in Kenya.". In: journal.; 1998.
O. PROFNDINYA-ACHOLAJ. "Lewis P, Nduati R, Kreiss JK, John GC, Richardson BA, Mbori-Ngacha D, Ndinya-Achola J, Overbaugh J.Cell-free human immunodeficiency virus type 1 in breast milk. J Infect Dis. 1998 Jan;177(1):34-9.". In: J Infect Dis. 1998 Jan;177(1):34-9. IBIMA Publishing; 1998. Abstract
{ Breast-feeding may be an important route of human immunodeficiency virus type 1 (HIV-1) vertical transmission in settings where it is routinely practiced. To define the prevalence and quantity of HIV-1 in cell-free breast milk, samples from HIV-1-seropositive women were analyzed by quantitative competitive reverse transcription-polymerase chain reaction (QC-RT-PCR). HIV-1 RNA was detected in 29 (39%) of 75 specimens tested. Of these 29 specimens, 16 (55%) had levels that were near the detection limit of the assay (240 copies/mL), while 6 (21%) had >900 copies/mL. The maximum concentration of HIV-1 RNA detected was 8100 copies/mL. The prevalence of cell-free HIV-1 was higher in mature milk (47%) than in colostrum (27%
N PROFNYAGAP. "Lilly C. Bebora, P.N. Nyaga and C.O. Kimoro. (1998). Comparason of immune responses of two Salmonella gallinarum strains viewed as posssible vaccines for fowl typhoid in Kenya. Onderspoort Journal of Vet. Res. Vol. 65.67-73.". In: Bull. Anim. Hlth. Prod. Afr. vol.58. no.1. au-ibar; 1998. Abstract

According to the statements made by a number of scholars, in the 80's East African Anglophone novel, which once received a nickname of "social documentary", began to lose gradually its social commitment. Many of the writers known previously as the most active supporters of the social trend, moved their attempts to other literan areas - criminal novel ("Weapon of hunger" by Meja Mцangi, 1989), love story (Yussuf Dawood's "Off my chest", 1988), even children's literature (books for children in Gikuyu, written by Ngugi wa Thiong'o). However, in the late 80's and early 90's East African Anglophone novel stepped onto a new level of social trend, moving from "social documentary" to "social epic". The authors now are trying to sum up the historical experience of East African countries over a large time span, and to that effect appeal mostly to elaborate and spacious literary forms, such as epic novel. These authors, although chosen one and the same literary form, are showing clearly their inclinations towards different styles of writing. For example, Tanzanian author Moyez Vassanji in his novel "The gunny sack" (1989) makes a rather convincing attempt to replant on East African soil the method of "mythological writing", previously used by such author as Gabriel Garcia Marquez. The novel definitely appeals not only to local reader, but to a wider international audience; on its pages the author manages to restore not only the fate of several generations of Indian family, but even the slightest details of their mentality, using myth as one of the basic means for changing the dimensions of time and space, according to the logic of the narration. The development of Kenyan novel in the early 90's confirms also one of the main tendencies in modem literature - bridging between "elite" and popular fiction. The first attempt of an epic novel in Kenyan Anglophone literature was, oddly enough, made by the veteran of Kenyan popular fiction David Maillu in his "Broken drum" H991). The novel hardly aims the widest reading public - nevertheless, stylistically it bears distinct features of popular fiction, such as crime story, romance, etc. Popular novel in East Africa also shows certain inclination towards urgent social themes, but the authors inevitably uses the artistic means they feel most happy with - that is, the style of popular fiction. For example, the "clash of cultures" - the experience of young Africans studying abroad - is presented in the form of a picaresque ("Times beyond" by Omondi Makoloo, 1992) or love story ("The girl from Uganda" by Tengio Urrio, 1993); feministic problems are spiced with sentimentalism ("Judy the nun" by P .Waweru, 1990); the thoughts on the hardships of younger generation are guised in Bildungs roman ("The plight of succession" by a Tanzanian Prosper Rwegoshora, 1990). At the same time, some authors, who have been ploughing successfully the field of pop fiction for a few decades, show their interest in more elaborate literary forms ("Dedan Kimathi: the real story" by Samuel Kaluga, 1990). All the mentioned facts do not allow us to state that the division into popular and elite novel will disappear within the foreseeable future. However, the most interesting developments seem to take place precisely in the field of bridging between these two branches of East African fiction.

O. DRBUKACHIFREDERICK. "Lown B, Bukachi F, Xavier R. Health information in the developing world. Lancet. 1998 Oct;352 Suppl 2:SII34-8.". In: East Afr Med J. 2001 Jul;78(7 Suppl):S43-7. UN-HABITAT; 1998. Abstract

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OBJECTIVE: To assess the clinical outcome of successful percutaneous transluminal coronary angioplasty (PTCA) in patients with poor ventricular function. METHODS: Analysis of angiographic, echocardiographic and clinical records of patients with severe LV dysfunction who underwent PTCA from January 1, 1995 to December 31, 1997 was undertaken. Forty-one patients aged 63+/-10 years, 36 men, all with significant coronary artery disease and impaired LV function (fractional shortening, FS<or=20%) were identified. Patients' data before and after angioplasty were analyzed. RESULTS: Post PTCA: angiographic success was 95.2%. Major complications occurred in 19.5% and hospital mortality was 2.7%. At 6 months after PTCA:LV fractional shortening (FS) increased from 15.9+/-3.4% to 19.6+/-6.6%

PROF. KOKWARO JOHNO. "Luo Biological Dictionary (Jointly authored with Prof. Timothy Johns of McGill University, Canada).". In: A well researched ethnobiological lexicon describing all the plants and animals known to and used by the Luo community in East Africa. University of Nairobi Press; 1998. Abstract
Total number of pages: 515, including 35 pages of colour illustrations.
PROF. KOKWARO JOHNO. "Luo Biological Dictionary; 264pp 1998 East African Educ. Publ.". In: Journal Of Ethnobiology Volume 25, Issue 1 (March 2005) Pp. 129. University of Nairobi Press; 1998. Abstract
Total number of pages: 515, including 35 pages of colour illustrations.
JOAB PROFBWAYOJOB, O. PROFANZALAAGGREY. "Luscher MA, Choy G, Njagi E, Bwayo JJ, Anzala AO, Ndinya-Achola JO, Ball TB, Wade JA, Plummer FA, Barber BH, MacDonald KS.Naturally occurring IgG anti-HLA alloantibody does not correlate with HIV type 1 resistance in Nairobi prostitutes.AIDS Res Hum Retro.". In: AIDS Res Hum Retroviruses. 1998 Jan 20;14(2):109-15. Asian Economic and Social Society; 1998. Abstract
In an effort to identify an immunological basis for natural resistance to HIV-1 infection, we have examined serum antibody responses to HLA class I antigens in female prostitutes of the Nairobi Sex Workers Study. Anti-HLA antibodies are known to block HIV infectivity in vitro and can be protective against SIV challenge in macaques immunized with purified class I HLA. Thus, it was postulated that broadly cross-reactive alloantibodies recognizing common HLA alleles in the client population might contribute to the prevention of heterosexual transmission of HIV. In fact, 12% of the women were found to have serum IgG antibodies against class I alloantigens. However, this alloantibody did not correlate with the HIV status of the women and was found in a similar proportion of HIV-positive and HIV-resistant women. The observed levels of alloantibody did not increase with HIV infection in susceptible individuals, suggesting that potential antigenic mimicry between HIV and host HLA class I antigens does not significantly increase levels of anti-class I antibodies. The lack of correlation between serum anti-allo-class I HLA antibodies and the risk of sexual transmission indicates that this humoral immune response is unlikely to be the natural mechanism behind the HIV-resistance phenotype of persistently HIV-seronegative women. This result, however, does not preclude the further investigation of alloimmunization as an artificial HIV immunization strategy.
JOAB PROFBWAYOJOB, O. PROFANZALAAGGREY. "Luscher MA, Choy G, Njagi E, Bwayo JJ, Anzala AO, Ndinya-Achola JO, Ball TB, Wade JA, Plummer FA, Barber BH, MacDonald KS.Naturally occurring IgG anti-HLA alloantibody does not correlate with HIV type 1 resistance in Nairobi prostitutes.AIDS Res Hum Retro.". In: AIDS Res Hum Retroviruses. 1998 Jan 20;14(2):109-15. John Benjamins Publishing Company; 1998. Abstract
In an effort to identify an immunological basis for natural resistance to HIV-1 infection, we have examined serum antibody responses to HLA class I antigens in female prostitutes of the Nairobi Sex Workers Study. Anti-HLA antibodies are known to block HIV infectivity in vitro and can be protective against SIV challenge in macaques immunized with purified class I HLA. Thus, it was postulated that broadly cross-reactive alloantibodies recognizing common HLA alleles in the client population might contribute to the prevention of heterosexual transmission of HIV. In fact, 12% of the women were found to have serum IgG antibodies against class I alloantigens. However, this alloantibody did not correlate with the HIV status of the women and was found in a similar proportion of HIV-positive and HIV-resistant women. The observed levels of alloantibody did not increase with HIV infection in susceptible individuals, suggesting that potential antigenic mimicry between HIV and host HLA class I antigens does not significantly increase levels of anti-class I antibodies. The lack of correlation between serum anti-allo-class I HLA antibodies and the risk of sexual transmission indicates that this humoral immune response is unlikely to be the natural mechanism behind the HIV-resistance phenotype of persistently HIV-seronegative women. This result, however, does not preclude the further investigation of alloimmunization as an artificial HIV immunization strategy.
V. DRMITULLAHWINNIE. "The Land Question and Politics of Tenure Reforms in Kenya, in IRDCurrents, No. 12, Department of Rural Development Studies, Swedish University of Agricultural Sciences, Uppsala, 1997.". In: The Politics of Transition in Kenya: From Kanu to Narc. Nairobi: Heinrich Boll Foundation. ELOQUENT BOOKS NY, Strategic Book Group, Connecticut, USA. ISBN-978-1-60911-081-9.Pages1; 1997. Abstract
Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} Products of gene modification have vast implications. Creating public awareness and disseminating information on the subject seeks to demystify some of the widely held falsehoods regarding genetically modified products. This is an informative, thorough and easy to understand guidebook that aims to enlighten and debunk some of the commonly held misconceptions on products of gene modification and to give the reader a better understanding of the role genetic modification will play. The review sheds light on the safety, and application of these products in medicine, the food industry and other areas, especially those where genetic modification may represent a cheap, faster, credible, viable alternative in achieving sustainable development among resource-poor communities.
K. DRKANYINGAHENRY. "The Land Question and Politics of Tenure Reforms in Kenya, in IRDCurrents, No. 12, Department of Rural Development Studies, Swedish University of Agricultural Sciences, Uppsala, 1997.". In: Citizenship and Rights: The Failures of Post-colonial State,Globalisation and Citizenship, Special issue of Africa Development Vol.(XXVIII) No. 1&2. Korean Society of Crop Science and Springer; 1997.
OMOLO PROFWANGOEMMANUEL. "Langat D.K., Johnson P.M., Rote N.S., Mwenda J.M., Owiti G.O.,Wango E.O. (1997). Characterisation of HIV/SIV cross-reactive antigens expressed in normal baboon placental villous tissue. J. Reprod.Immunol. 34, 66.". In: Biennial Scientific Conference of the Faculty of Veterinary Medicine. Advances in Veterinary Education and Animal Sciences. 5th. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1997. Abstract

SUMMARY LIII)' lIIorpllOlogiClI changcs ill the goat ,csris after:. sillgle illlraperilOlieal injec,ioll of ethalle ,lillie' I.:lIIeslll"llOnarc (EI )S) werc investigatcd mint; (1Orh liglH alld deCll'On microscopy. The (olllpolind was ;almillistered at two dose Icvels: 75 mgll

OMOLO PROFWANGOEMMANUEL. "Langat D.K., Johnson P.M., Rote N.S., Owiti G.O., Wango E.O. and Mwenda J.S.(1997). Localisation of HIV/SIV cross-reactive antigens expressed in normal baboon placental tissues. J. Mol. Medicine, 75,(7):B178.". In: Biennial Scientific Conference of the Faculty of Veterinary Medicine. Advances in Veterinary Education and Animal Sciences. 5th. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1997. Abstract

SUMMARY LIII)' lIIorpllOlogiClI changcs ill the goat ,csris after:. sillgle illlraperilOlieal injec,ioll of ethalle ,lillie' I.:lIIeslll"llOnarc (EI )S) werc investigatcd mint; (1Orh liglH alld deCll'On microscopy. The (olllpolind was ;almillistered at two dose Icvels: 75 mgll

RAI MRVYASYASHWANT. "The Law of Torts, a Booklet for paralegal trainees (Claripress Ltd, Nairobi.". In: Journal of the Kenya National Academy of Science Nairobi 20-43.; 1997. Abstract
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RAI MRVYASYASHWANT. "The Law of Torts, a Booklet for paralegal trainees (Claripress Ltd, Nairobi,).". In: Lesotho Law Journal, 177-198 (2000).; 1997. Abstract
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PATRICIA PROFKAMERMBOTEI. "Law, colonialism and Environmental Management in Africa 6 Review of Europea Community & International Environmental Law 1997), p. 23 (with Philippe Cullet).". In: journal. Israel Journal of Veterinary Medicine; 1997. Abstract
Antibody responses to a conventional rabies preexposure regimen of a new purified Vero cell rabies vaccine (PVRV) and a human diploid cell vaccine (HDCV) were compared in 80 healthy Kenyan veterinary students. Forty-three of the students received the PVRV and 37 received the HDCV on days 0, 7, and 28. Antibody responses were monitored using the rapid fluorescent-focus inhibition test (RFFIT) and an inhibition enzyme immunoassay (INH EIA) on days 0, 7, 28, and 49. Both vaccines elicited a rapid antibody response. A good correlation between the RFFIT titers and the INH EIA titers was obtained (r = 0.90). Our results also showed that the INH EIA was more reproducible and might therefore be a suitable substitute for the more expensive and less reproducible RFFIT. The geometric mean titers determined by both tests in the two groups of students were statistically similar during the test period. The RFFIT and the INH EIA gave comparable geometric mean titers, which differed significantly only on day 28 in the PVRV group. The effect of the new PVRV is comparable to that of the more expensive HDCV, as determined by the present test systems. The PVRV could therefore be the vaccine of choice, especially in tropical rabies-endemic areas, where the high cost of the HDCV has confined its use to a privileged few.
OKECH MROWITIMAURICED. "'Law, Consumer Protection and Education', The Kenya Adult Educator, Vol. 3, No. 2, 21-33.". In: Victoria Walter and Debbie Betts (eds), Safeguarding Human Rights in Eastern Africa (FES, Kampala), 77. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1997. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
WAFULA DRMUYILAJACKSON. "Leadership from the Grave with Special Reference to the Bukusu Traditional Society".". In: Mila (N.S.) Vol.2 1997. Institute of African Studies, University of Nairobi; 1997. Abstract
Introduction The Centre for Open and Distance Learning has been established to facilitate the Internal Faculties in launching and managing their programmes using distance mode with a view to increasing access to university education and provide equity in higher education to the learners all over the country. Operational Strategies The operational strategies that have been set up involve collaborative arrangements between the CODL and the Internal Faculties in the development of Study Materials and Learner support Services for off-campus students. The professional in open and distance learning are availed by the Centre to serve the Faculties as trainers while the Faculties provide academic expertise who are facilitated through participatory methods involving application of knowledge, skills and strategies to develop study materials in their respective subjects. Focus The Centre is currently working with Faculties of Science, Commerce and Arts. The Material development process involves training, writing, reviewing and editing followed by conversion to e-content and audio modes. Conclusion These collaborative arrangements will increase access to higher education make significant contribution in the realization of educational Millennium Goals in Kenya where only 20% of all those who qualify obtain admission in the public universities.
JOHN DRMWANGI. "Learning Achievement in Economics in Kenyan Secondary Schools.". In: Article for publication in Independent. au-ibar; 1997. Abstract
   
P. PROFSITUMAFRANCISD. "Legal Framework for Conservation,ownership,Access and Utilization of African Biodiversity:Medical plant and Food Crops,A paper presented at the OAU scientific Technical and Research Commission/Kenya Industrial Property Office/Development partners workshop."; 1997. Abstract

New Directions in water legislation in Kenya?. A Paper presented as the National Workshop on environmental Governance in kenya, held at the UNEP Headquarters Gigiri, Nairobi, March 29-30. 2000

JAMES PROFODEK. "Legal Issues on Ownership of Forest and Wildlife Resources in Transmara District, January, Konrad Adenaeur Stiftung.". In: Paper presented at the WIPO High Level Forum on IP Policy and Strategy, Tokyo . Prof. James Otieno-Odek; 1997. Abstract
J. O. Midiwo, A. Yenesew, B. F. Juma, S. Dereses, J. A. Ayoo, A. Aluoch and S. Guchu There are several described medicinal plants in Kenya from a flora of approximately 10,000 members. Strong cross-medical information from the 42 ethnic groups points to the high potential of some of these species. The Myrsinaceae are well established ethno-anthelmintics and anti-bacterials. They are harbingers of long alkyl side chain benzoquinones which clearly have a protective function from their histochemical disposition. The main benzoquinone in the sub-family Myrsinodae is embelin while for the Maesodae it is maesaquinone together with its 5-acetyl derivative; the distribution of these benzoquinones by their alkyl side chain length or the presence/absence of a 6-methyl group is in accord with morphological sub-family de-limitation. The benzoquinones showed anti-feedant, anti-microbial, phytotoxic, acaricidal, insecticidal and nematicidal activity. Many other benzoquinones of medium and minor concentration were also isolated and characterised. Some plants belonging to the Polygonaceae which are widely used as ethno-anthelmintics have been studied. The common anthelmintic anthraquinones were obtained from all five Rumex species while the naphthalenic acetogenin derivative, nepodin was more selectively distributed. The leaf of Polygonum senegalense is up to 17% surface exudate; about thirteen non polar flavonoid derivatives (chalcones, dihydrochalcones, flavanones and a flavone) have been isolated from it. From the internal aerial tissues of this plant, the major flavonoids were common flavonoids, quercetin, kaempferol, luteolin and their glycosides. The only unique compound isolated from this plant was 2prime-glucosyl-6prime-hydroxy-4prime-methoxydihydrochalcone whose aglycone, uvangolatin is part of the exudate mixture. Other leaf exudate plants studied include the stomach-ache medicine, Psiadia punctulata (Compositae) from which novel methylated flavonoids, kaurene and trachyloban diterpenes have been found
L DRLEGGEPATRICK. "Legge, P.L. (1997): The application of Multitemporal Remote Sensing Data and Aerial Photographs in the management and monitoring of Coastal areas and parks in Kenya,.". In: the proceedings of the Fourth International Conference on Remote sensing And Costal Environment, Orlando, Florida, USA. Heinrich Boll Foundation.; 1997.
L DRLEGGEPATRICK. "Legge, P.L.; (): Copper mineralization in East Equatorial province, South.". In: A case Study of Aswa Shear Zone, Lugari, Chekalini Area Western Kenya. Heinrich Boll Foundation.; 1997.
L DRLEGGEPATRICK. "Legge, P.L.; (1997): Copper mineralization in East Equatorial province, South Sudan, Brussels, Belgium.". In: presentment at the In. Conference. Heinrich Boll Foundation.; 1997.
J. DRMUNGUTIKAENDI. "Lets share with Others: Developing Radio and Illustration Materials with and for Rural Women. World Health Organization, Geneva, Switzerland.". In: Gender Concerns in Sustainable Community Development: A Research Agenda (Paper presented for publication to UNESCO/UNITWIN, University of Nairobi). Lelax Global (K) Ltd; 1997. Abstract
The book is a biography of the author. He begins with fundamenbtal question whether we can determine our destiny or we are just fulfiling what has already been ordained. He then explains how he has grown over the yeas experiencing changes.  
NJUGUNA PROFNGETHE. "Linking Policy and Research: Towards Enhancing the Policy Advocacy Capacity of Civil Society in Kenya. An IPAR project proposal submitted to a number of Donors in 1997.". In: From Sessional Paper No. 10 to Structural Adjustment. Published by IPAR, Nairobi.; 1997. Abstract
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N PROFOGOLAELIJAHS. "Lodenyo H.A, McLigeyo S.O OGOLA E.N.Cardiovascular disease in elderly patients at the Kenyatta national hospital. East Africa. J.741: 647,1997.". In: East Africa. J.741: 647,1997. Kisipan, M.L.; 1997. Abstract
A prospective study to determine the prevalence and profile of cardiovascular disease in elderly patients admitted into the medical wards, Kenyatta National Hospital, was carried out between July 1991 and January 1992. Two hundred and two patients over 60 years of age were admitted into the medical wards over this period. This formed seven per cent of the total medical admissions. Two of these refused to take part in the study. Of the 200 elderly patients evaluated for cardiovascular disease, 146 (73%) were between 60 and 75 years of age with only 26 (13%) being over 85 years. Fifty seven per cent were males. Clinical evidence of cardiovascular disease was present in 79 (39.5%) of the patients evaluated. There was no sex difference in the prevalence of cardiovascular disease as judged from clinical evaluation (37.7% males versus 41.9% females, p > 0.05). Cardiovascular diseases in our medical in-patients at Kenyatta National Hospital are common and especially so with hypertension which plays an important role in the aetiology of congestive heart failure and cerebravascular accidents. Cardiac arrhythmias are also common though not necessarily symptomatic. Rheumatic heart disease and cardiomyopathies were uncommon in our study population. A community-based survey is needed to determine the true prevalence of cardiovascular diseases in the elderly and their contribution to morbidity in this sector of the population.
O PROFMCLIGEYOSETH. "Lodenyo HA, McLigeyo SO, Ogola EN.Cardiovascular disease in elderly in-patients at the Kenyatta National Hospital, Nairobi-Kenya. East Afr Med J. 1997 Oct;74(10):647-51.". In: East African Medical Journal. 74(10):605-606, 1997. University of Nairobi.; 1997. Abstract
A prospective study to determine the prevalence and profile of cardiovascular disease in elderly patients admitted into the medical wards, Kenyatta National Hospital, was carried out between July 1991 and January 1992. Two hundred and two patients over 60 years of age were admitted into the medical wards over this period. This formed seven per cent of the total medical admissions. Two of these refused to take part in the study. Of the 200 elderly patients evaluated for cardiovascular disease, 146 (73%) were between 60 and 75 years of age with only 26 (13%) being over 85 years. Fifty seven per cent were males. Clinical evidence of cardiovascular disease was present in 79 (39.5%) of the patients evaluated. There was no sex difference in the prevalence of cardiovascular disease as judged from clinical evaluation (37.7% males versus 41.9% females, p > 0.05). Cardiovascular diseases in our medical in-patients at Kenyatta National Hospital are common and especially so with hypertension which plays an important role in the aetiology of congestive heart failure and cerebravascular accidents. Cardiac arrhythmias are also common though not necessarily symptomatic. Rheumatic heart disease and cardiomyopathies were uncommon in our study population. A community-based survey is needed to determine the true prevalence of cardiovascular diseases in the elderly and their contribution to morbidity in this sector of the population.
KINYANJUI DRMURIITHIMOSES. "Labour Economics: Text for Distance learners. University of nairobi.". In: A study of Nyeri. I.E.K Internatioanl Conference l; 1996. Abstract
This paper develops an improved real and reactive power control technique using linear programming (LP) for an integrated power system. The problem is decomposed into two subproblems comprising real (P) and reactive power (Q) modules, and, using a unified approach, the real power generation, voltage magnitude, and transformer tap settings are optimized. The objective function is the fuel cost which is minimized in both the P and Q modules, subject to the operating constraints. The P-Q decomposition combined with the LP formulation improve the computation speed. The paper has another advantage of using the same cost objective function for both modules, unlike other conventional methods which use the power loss function for the Q module. The LP formulation is used for both the P and Q optimization modules, utilizing the revised simplex method which is normally available in a mainframe computer.
AKATCH PROFSAMUELO. ""Lake Victoria Wetlands Programme: "An Inventory Assessment and Mapping Programme" in Dying Lake Victoria (1996) Annex VI pp 70.". In: Federation Proceedings, 31 1470. Journal of Natural Products; 1996.
OKOTH PROFOGENDOHASTINGW. ""Land tenure and land administration in Tanzania: a paper for a Workshop on Land Use Planning and Land Tenure System", Sokoine University of agriculture, Morogoro, Tanzania, February.". In: Cent. Afri. J. Pharm.Sci. 5(3): 60-66. Cent. Afri. J. Pharm.Sci. 5(3): 60-66; 1996. Abstract
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
OKOTH PROFOGENDOHASTINGW. ""Land tenure and natural resource management: the Kenya experience", paper for the OSS/IGADD/ECA Workshop on Land tenure, Addis Ababa Ethiopia, March.". In: Cent. Afri. J. Pharm.Sci. 5(3): 60-66. Cent. Afri. J. Pharm.Sci. 5(3): 60-66; 1996. Abstract
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
OKOTH PROFOGENDOHASTINGW. ""Land tenure and resource management: a comment:" in ENTWICKLUNG LANDLICHER RAUM Vol. 3 No. 2 Bonn, Germany.". In: Cent. Afri. J. Pharm.Sci. 5(3): 60-66. Cent. Afri. J. Pharm.Sci. 5(3): 60-66; 1996. Abstract
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
O PROFMUMMAALBERT. ""Land Tenure and Water Resources," in In Land We Trust: Environment, Private Property & Constitutional Change, Juma, C & Ojwang J.B. (eds) Initiatives Publishers/ACTS press, (1996), at p. 143, with A.F. Juma & C Torori).". In: UCLA Journal of Environmental Law and Policy, vol. 19, 2000/2001, No. 1 at p. 181. Departmental seminar; 1996. Abstract
Oyieke H.A. and Misra A.K:
OMOLO PROFWANGOEMMANUEL. "Langat D., Mwenda J., Chege G., and Wango E.O. (1996).Characterisation of retroviral related antigens expressed in normal baboon placental and other tissues. .". In: Kenya Obstetrical and Gynaecological Society, 21st Annual Scientific Conference, 21st-23rd February. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1996. Abstract

SUMMARY LIII)' lIIorpllOlogiClI changcs ill the goat ,csris after:. sillgle illlraperilOlieal injec,ioll of ethalle ,lillie' I.:lIIeslll"llOnarc (EI )S) werc investigatcd mint; (1Orh liglH alld deCll'On microscopy. The (olllpolind was ;almillistered at two dose Icvels: 75 mgll

OMOLO PROFWANGOEMMANUEL. "Langat D.K., Mwenda J.M., Owiti G.E.O. and Wango E.O. (1996).Biochemical characterisation of retroviral-related antigens expressed in normal baboon placental tissues.". In: First Pan African Conference on Biochemistry and Molecular Biology, Nairobi, Kenya. Abstr. I-8. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1996. Abstract

SUMMARY LIII)' lIIorpllOlogiClI changcs ill the goat ,csris after:. sillgle illlraperilOlieal injec,ioll of ethalle ,lillie' I.:lIIeslll"llOnarc (EI )S) werc investigatcd mint; (1Orh liglH alld deCll'On microscopy. The (olllpolind was ;almillistered at two dose Icvels: 75 mgll

PATRICIA PROFKAMERMBOTEI. "'Law and the Status of Women in Kenya' in Janet K. Macharia ed., Women Laws, Customs and Practices in East Africa: Laying the foundation (1996) (with Victoria Mucai-Kattambo & Janet Kabeberi-Macharia).". In: journal. Israel Journal of Veterinary Medicine; 1996. Abstract
Antibody responses to a conventional rabies preexposure regimen of a new purified Vero cell rabies vaccine (PVRV) and a human diploid cell vaccine (HDCV) were compared in 80 healthy Kenyan veterinary students. Forty-three of the students received the PVRV and 37 received the HDCV on days 0, 7, and 28. Antibody responses were monitored using the rapid fluorescent-focus inhibition test (RFFIT) and an inhibition enzyme immunoassay (INH EIA) on days 0, 7, 28, and 49. Both vaccines elicited a rapid antibody response. A good correlation between the RFFIT titers and the INH EIA titers was obtained (r = 0.90). Our results also showed that the INH EIA was more reproducible and might therefore be a suitable substitute for the more expensive and less reproducible RFFIT. The geometric mean titers determined by both tests in the two groups of students were statistically similar during the test period. The RFFIT and the INH EIA gave comparable geometric mean titers, which differed significantly only on day 28 in the PVRV group. The effect of the new PVRV is comparable to that of the more expensive HDCV, as determined by the present test systems. The PVRV could therefore be the vaccine of choice, especially in tropical rabies-endemic areas, where the high cost of the HDCV has confined its use to a privileged few.
L DRLEGGEPATRICK. "Legge, P.L.,J.O. Barongo, N. Opiyo-Aketch, E.M. Mathu, i.O. Nyambok, (1996):Development in earth Science Education in East Africa.". In: Joint Special Publication, Commission on Geosciences Education and Training of IUGS, AGID Special Publication Series No.10; 49-51. Balkema, Rotterdam. Heinrich Boll Foundation.; 1996.
K PROFKAMAUREUBEN. "Lema VM, Rogo KO, Kamau RK. Induced abortion in Kenya: its determinants and associated factors. East Afr Med J 1996; 73: 164-68.". In: East Afr Med J 1996; 73: 164-68. Journal of School of Continuous and Distance Education ; 1996. Abstract
Kamau RK, Osoti AO, Njuguna EM. Department of Obstetrics and Gynaecology, College of Health Sciences, University of Nairobi, P.O. Box 1%76-00202, Nairobi, Kenya. BACKGROUND: Cancer of the uterine cervix is the most common female cancer in Kenya. Despite being preventable, it is often diagnosed when it is already late. For this reason, only palliative therapy is provided. Hence, it is expected that their daily routines and that of their caregivers are severely disrupted. OBJECTIVES: To determine the extent to which diagnosis and treatment of inoperable cervical carcinoma affects quality of life (QOL). DESIGN: Cross-sectional descriptive study. Setting Radiotherapy Department at the Kenyatta National Hospital. SUBJECTS: Women undergoing radiotherapy for inoperable cervical cancer. RESULTS: There is high prevalence of profound disruptions in nearly all domains of QOL. In the social domain, between 33% and 44% had the perception that family members and friends had withdrawn social support. Reduction in various economic facets was reported by 47.4%-52.6%, with 44.7% reporting a fall in the overall living standards. There were significant changes in the sexual domain, as a result in which 28.3% reported marital discordance. In the personality domain, decreased self-esteem and self-projection in life occurred in 30.9% and 36.2% respectively. On functional outcomes (EORTC QLQ-C30), only 32%-41% reported not being affected in the various facets of emotional function. Physical functions were affected in 19%-79%, role functions in 69%-75%; symptoms in 49%-80%; cognitive functions in 46%-56%; social functions in 63%-71% and financial aspects by 63%. On global QOL, 53% and 47% respectively reported high level disruption in overall physical health and overall QOL. CONCLUSION: Severe deterioration of QOL occurs as a result of diagnosis of inoperable cervical cancer and subsequent therapies. For this reason there is need to establish severe disease and end-of-life research and management services that would ensure better coping with cancer for patients and for home-based caregivers. PMID: 17633581 [PubMed - indexed for MEDLINE]
S PROFKIGONDUCHRISTINE. "Leslie PW, Campbell KL, Little MA, Kigondu CS. Evaluation of reproductive function in Turkana women with enzyme immunoassays of urinary hormones in the field.Hum Biol. 1996 Feb;68(1):95-117.". In: Hum Biol. 1996 Feb;68(1):95-117. uon press; 1996. Abstract
Department of Anthropology and Carolina Population Center, University of North Carolina, Chapel Hill 27516, USA. The frequently reported observation that nomadic populations have lower fertility than their settled counterparts is often attributed to what are perceived as harsh, stressful conditions under which the nomads live. But the consequences of the hypothesized stresses for the reproductive biology or demography of these populations have been documented only a little. Traditionally, the Turkana of northwest Kenya are nomadic herders, but increasing numbers have settled on agricultural development schemes. We used an array of hormonal assays along with anthropometric indexes of nutritional status and interviews covering reproductive history, recent menstruation, diet, and health to compare reproductive function in nomadic and settled Turkana women. First morning urine samples were collected for three consecutive days during a series of surveys. Human choriogonadotropin (hCG; a marker for pregnancy), luteinizing hormone (LH; an indicator of ovulation), and pregnanediol glucuronide (PdG; an indicator of postovulatory luteal function) were assessed in the field with commercially available dipstick enzyme immunoassays. These assays along with the interview data allowed us to determine the reproductive status (e.g., pregnant or cycling, and if cycling, which phase of the ovarian cycle) of 166 nomadic and 194 settled Turkana women. The cross-sectional classifications allowed inferences of conception rates and normality of ovarian function. Follow-up surveys provided rates of pregnancy loss. Compared with the settled women, the nomadic women exhibited lower pregnancy rates and cycling nomadic women were less likely to show evidence of ovulation or luteal function. These results suggest that reproductive function of the nomadic women is diminished relative to the settled women. However, the settled women experienced a much higher rate of pregnancy loss, which may mean that their effective fecundability is in fact lower than that of the nomadic women. This study is the first to apply such a wide range of hormonal assays in the field. It demonstrates that field-based assays are feasible and robust and can play an important role in epidemiological and biodemographic studies, even in remote locations under conditions that would ordinarily be considered incompatible with on-site laboratory analysis.
ASWANI PROFMWANZIHELLENORONGA. "Let the Factory Close in Our Secret Lives. Nairobi: Phoenix Publishers.". In: University of Nairobi Press. Elsevier; 1996.
M PROFKIMANIPAUL. "Linkage relationships among loci controlling morphological traits in cowpea (Vigna unguiculata (L.) Walp.). Euphytica 92: 307-311.". In: Paper presented in the International Conference on Integrated pest Management for Sub-saharan Africa, 8-12 Sept 2002, Kampala, Uganda. EAMJ; 1996. Abstract
A cross sectional study of 115 patients admitted at the Department of Orthopedics, Kenyatta National Hospital, Nairobi, Kenya was carried out to determine the prevalence and antibiotic susceptibility of Staphylococcus aureus isolated from infected wounds. The prevalence of Staphylococcus aureus was 33.0 %. The drugs tested and their corresponding sensitivity was amoxycillin (13.2 %), co-amoxyclav (39.5 %), oxacillin (55.3 %), erythromycin (44.7 %), gentamicin (60.5 %), ciprofloxacin (62.2 %), minocycline (86.8 %), cefuroxime (57.9 %), and clidamycin (84.2 %). These results show the sensitivity profile of Staphylococcus aureus and can be used to choose suitable drugs in the management of wounds for hospitalized patients.
W. PROFMAKAWITIDOMINIC. "Lomo PO, Makawiti DW, Konji VN.Thyroid status and adenosine triphosphatase activity in experimental Trypanosoma congolense infection in rabbits. Br Vet J. 1996 Nov;152(6):659-67.". In: Br Vet J. 1996 Nov;152(6):659-67. Groebner-Bases-Bibliography-RICAM; 1996. Abstract
The effect of trypanosome infection on the plasma levels and ratios of tri-iodothyronine (T3) and thyroxine (T4) as well as the activity of mitochondrial adenosine triphosphatase (ATPase) were investigated. Three groups of sexually mature white New Zealand rabbits were used. Group 1 consisted of the normal non-infected rabbits, group 2 were experimentally infected with Trypanosoma congolense and group 3 were infected but given replacement doses of thyroxine. The infected animals (group 2) showed a rapid decline in both T3 and T4 but an increase in the T3/T4 ratio indicating differential production or clearance rates between the two hormones. The mitochondrial ATPase activity was found to be depressed in the infected group whereas there was no significant difference in the ATPase activity between the non-infected (group 1) and infected-treated animals (group 2). It is postulated that trypanosome induced hypothyroid status may play a role in the impairment of mitochondrial ATPase activity, a key enzyme in energy metabolism.
ARIMI PROFMUTWIRIS, A MRKABURIAHF. "A longitudinal study of milk somatic cell counts and bacterial culture from cows on smallholder dairy farms in Kiambu District, Kenya.". In: journal. GIGA German Institute of Global and Area Studies, Hamburg, July 2009; 1996. Abstract
As part of an integrated study on health and production of dairy cattle on smallholder farms in central Average milk yield was low (5.8 kg/day; median = 5kg/day) and lactation length was long (20 months). Clinical mastitis risk was low (1% per month). Somatic cell counts (SCC) were high (median = 620 x 103); the previously suggested threshold of 300 000 cells/ml would classify 71% of quarters as positive for subclinical mastitis. Bacteria were commonly isolated, with S. aureus as the most common pathogen isolated (22.1% of all samples). Infections with mastitis pathogens, cow-age and milk yield were associated with increases in SCC. However, S. aureus was the only mastitis pathogen associated with decreased milk yield. Few specific mastitis control measures were applied. The only farm-level variable associated with high SCC was the method of drying off. Gradual drying off decreased SCC.
Kaduki KA, Ghiti A, Batty W, Allsopp DWE. "Laser applications of exact expressions for hole subband effective mass in arbitrarily shaped quantum wells grown along arbitrary crystal axes.". In: National Quantum Electronics Conference, QE-12 `95. Southampton, U.K.; 1995.
H.J. OJWANG. "Life and Message of a Biography."; 1995. Abstract

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S. PROFAKUNDABWENILEVI. "L. Abscisic acid (ABA) accumulation in roots and leaves of Vigna unguiculata L., Walp. under imposed water stress.". In: Legume Research J. 33:11-13. NISC Pty Ltd; 1995.
OLE PROFMALOIYGEOFFREYM. "LANGMAN, V.A., ROBERTS, T.J., BLACK, J., MALOIY, G.M.O., HEGLUND,N.C., WEBER, J.M. KRAM, R. and TAYLOR, C.R.(1995) Moving cheaply: energetics of walking in the African elephant.Journal of Experimental Biology 198, 629-632.". In: Annual Conference Society for integrative and Comparative Biology New Orleans Louisiana U.S.A. EAMJ; 1995. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
M DRWARUIRUROBERT. "Larsen, M., Nansen, P., Henriksen, S.Aa., Gr.". In: Joint Meeting of the Am. Soc. of Parasitologist and the Am. Association of Veterinary Parasitologists, Pittsburgh, Pennsylvania, USA, July 6-10. Journal of School of Continuous and Distance Education ; 1995. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Integrated vector management (IVM) for malaria control requires ecological skills that are very scarce and rarely applied in Africa today. Partnerships between communities and academic ecologists can address this capacity deficit, modernize the evidence base for such approaches and enable future scale up. Community-based IVM programmes were initiated in two contrasting settings. On Rusinga Island, Western Kenya, community outreach to a marginalized rural community was achieved by University of Nairobi through a community-based organization. In Dar es Salaam, Tanzania, Ilala Municipality established an IVM programme at grassroots level, which was subsequently upgraded and expanded into a pilot scale Urban Malaria Control Programme with support from national academic institutes. Both programmes now access relevant expertise, funding and policy makers while the academic partners benefit from direct experience of community-based implementation and operational research opportunities. The communities now access up-to-date malaria-related knowledge and skills for translation into local action. Similarly, the academic partners have acquired better understanding of community needs and how to address them. Until sufficient evidence is provided, community-based IVM remains an operational research activity. Researchers can never directly support every community in Africa so community based IVM strategies and tactics will need to be incorporated into undergraduate teaching programmes to generate sufficient numbers of practitioners for national scale programmes. Academic ecologists at African institutions are uniquely positioned to enable the application of practical environmental and entomological skills for malaria control by communities at grassroots level and should be supported to fulfil this neglected role.
OLUOCH PROFATINGAJOHNERNEST. "Lateral Condylar Mass Fracture of the Elbow in Children.". In: African Journal of Medical Practice, Vol. 2: 160 - 162. E Afr Med J; 1995. Abstract
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OKECH MROWITIMAURICED. "'Legal Research for Public Awareness: A View', UNLJ No. 3, 92-102.". In: Victoria Walter and Debbie Betts (eds), Safeguarding Human Rights in Eastern Africa (FES, Kampala), 77. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1995. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
OLONDE PROFAMAYOERASTUS. "Lindley RI, Amayo EO, Marshall J, Sandercock PA, Dennis M, Warlow CP.Acute stroke treatment in UK hospitals: the Stroke Association survey of consultant opinion. J R Coll Physicians Lond. 1995 Nov-Dec;29(6):479-84.". In: J R Coll Physicians Lond. 1995 Nov-Dec;29(6):479-84. African Wildlife Foundation. Nairobi; 1995. Abstract
The aim of the Stroke Association survey was to document United Kingdom consultant opinion of the immediate treatment for patients with acute stroke. A national postal survey of all UK hospital consultant general physicians, geriatricians and neurologist was carried out in 1992/3. We identified 1,953 consultants who routinely cared for patients with acute stroke; 39% of them regularly used aspirin for patients with acute stroke and 10% used low-dose subcutaneous heparin. Other treatments were rarely used. There was much uncertainty about the effectiveness of all currently available acute stroke treatments; 73% of physicians were prepared to start aspirin before a CT scan, but a much smaller proportion would start heparin therapy without one. Twenty-seven percent of consultants would actively treat hypertension in the initial 24 hours after stroke. Routine aspirin for secondary prevention after ischaemic stroke was widely accepted, but blood cholesterol lowering by drugs was not. In conclusion, aspirin and heparin alone are the only routinely used treatments for the immediate treatment of acute stroke; other treatments are used sparingly or not at all. The great uncertainty about the value of all available acute stroke treatments should encourage participation in randomised controlled trials.
.O PROFGUMBELAWRENCE. "Load-Deformation Behaviour of Soils and En-Masse Grains. Proceedings of the Symposium on Unsaturated Soil Behaviour and Applications. Nairobi, Kenya. 22 - 23 August.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1995. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
W. PROFMAKAWITIDOMINIC. "Lomo PO, Makawiti DW, Konji VN. The effect of L-thyroxine on the anaemia response in Trypanosoma congolense infected rabbits. Vet Parasitol. 1995 Jun;58(3):227-34.". In: Vet Parasitol. 1995 Jun;58(3):227-34. Groebner-Bases-Bibliography-RICAM; 1995. Abstract

{ The development of anaemia is a major pathological manifestation in chronic trypanosomosis. The anaemia in African trypanosomosis coincides with a marked decrease in plasma concentration of both thyroxine (T4) and 3,5,3' triiodothyronine (T3). To evaluate the effect of trypanosome-induced hypothyroidism on the development of anaemia, sexually mature white New Zealand rabbits were used. Three groups were set up, each of ten rabbits: one group was infected with Trypanosoma congolense; the second group was infected but given replacement doses of thyroxine (treated); the third group was not infected. Small volumes of blood were collected for the determination of parasitaemia and packed cell volume (PCV). The concentrations of T3 and T4 were measured in plasma by radioimmunoassay. The decrease in PCV correlated closely (y = -0.38x + 15.2; r = 0.82

JOAB PROFBWAYOJOB, O. PROFANZALAAGGREY. "Low dose erythromycin regimen for the treatment of chancroid. Kimani J; Bwayo JJ; Anzala AO; MacLean I; Mwatha A; Choudri SH; Plummer FA; Ronald AR. East Afr Med J. 1995 Oct;72(10):645-8.". In: East Afr Med J. 1995 Oct;72(10):645-8. Asian Economic and Social Society; 1995. Abstract
The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. This cross-sectional study was conducted to measure the association between circumcision status and infection with HIV-1 among men with genital ulcer disease. Eight hundred and ten men participated in the study, of whom 190 (23%) were HIV-1-positive. A logistic regression model adjusted for behavioral and historical showed that HIV-1 positivity was independently associated with being uncircumcised (adjusted odds ratio [OR], 4.8; 95% confidence interval [CI], 3.3-7.2) and with a history of urethral discharge (adjusted OR, 2.0; 95% CI, 1.4-2.8). This association could not be explained by measures of sexual exposure to HIV-1 among this population. Male circumcision should be considered as an intervention strategy for AIDS control.
JOAB PROFBWAYOJOB, O. PROFANZALAAGGREY. "Low dose erythromycin regimen for the treatment of chancroid. Kimani J; Bwayo JJ; Anzala AO; MacLean I; Mwatha A; Choudri SH; Plummer FA; Ronald AR. East Afr Med J. 1995 Oct;72(10):645-8.". In: East Afr Med J. 1995 Oct;72(10):645-8. John Benjamins Publishing Company; 1995. Abstract

BACKGROUND: There is indirect evidence that HIV-1 exposure does not inevitably lead to persistent infection. Heterogeneity in susceptibility to infection could be due to protective immunity. The objective of this study was to find out whether in highly HIV-1-exposed populations some individuals are resistant to infection. METHODS: We did an observational cohort study of incident HIV-1 infection-among 424 initially HIV-1-seronegative prostitutes in Nairobi, Kenya, between 1985 and 1994. 239 women seroconverted to HIV-1 during the study period. Exponential, Weibull, and mixture survival models were used to examine the effect of the duration of follow-up on incidence of HIV-1 infection. The influence of the duration of exposure to HIV-1 through prostitution on seroconversion risk was examined by Cox proportional hazards modelling, with control for other known or suspected risk factors for incident HIV-1 infection. HIV-1 PCR with env, nef, and vif gene primers was done on 43 persistently seronegative prostitutes who remained seronegative after 3 or more years of follow-up. FINDINGS: Modelling of the time to HIV-1 seroconversion showed that the incidence of HIV-1 seroconversion decreased with increasing duration of exposure, which indicates that there is heterogeneity in HIV-1 susceptibility or acquired immunity to HIV-1. Each weighted year of exposure through prostitution resulted in a 1.2-fold reduction in HIV-1 seroconversion risk (hazard ratio 0.83 [95% CI 0.79-0.88], p < 0.0001). Analyses of epidemiological and laboratory data, show that persistent seronegativity is not explained by seronegative HIV-1 infection or by differences in risk factors for HIV-1 infection such as safer sexual behaviours or the incidence of other sexually transmitted infections. Interpretation: We conclude that a small proportion of highly exposed individuals, who may have natural protective immunity to HIV-1, are resistant to HIV-1. PIP: A cohort study conducted in 1985-94 among 424 prostitutes from Nairobi, Kenya, who were initially human immunodeficiency virus (HIV)-1 seronegative, tended to provide support for the observation that some individuals in highly exposed populations may be resistant to infection. During the 10-year study period, 239 of these women seroconverted. The overall HIV-1 incidence was 42/100 person-years. After the first 2 years of follow up, in which the majority of seroconversions occurred, HIV-1 prevalence reached a plateau and then began a steep decline. To determine whether the risk of HIV-1 infection declined over time as a result of the selection of resistance, incidence rates among women with less than 3 years' versus more than 3 years' duration of prostitution were compared for 1989-93. An increasing protective effect for each seronegative year of exposure was observed. The estimated cumulative protective effect for women practicing prostitution from 1984-93 and remaining seronegative, compared to women who entered prostitution in 1994, was over 100-fold. To rule out the possibility that the decrease in seroconversion with duration of exposure reflected differences in sexual behavior or immunity to sexually transmitted diseases that facilitate HIV transmission, Cox proportional hazards modelling was performed. The weighted duration of prostitution was independently associated with a decreased risk of seroconversion. Each weighted year of exposure resulted in a 1.2-fold decrease in risk. Women who seroconverted were more likely to report 1 or more regular partners and to use condoms with these partners than their counterparts who remained seronegative. Elucidation of the protective mechanisms and the factors mediating the development of immunity against HIV-1 could be important to HIV-1 vaccine research.

JOAB PROFBWAYOJOB. "Low dose of erythromycin in the treatment of chancroi. Kimani J, Maclean I, Anzala A, Bwayo J.J. East-AfricanMedical Journal. 1995 Oct; 72(10): 645-8.". In: East-AfricanMedical Journal. 1995 Oct; 72(10): 645-8. Asian Economic and Social Society; 1995. Abstract
The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. This cross-sectional study was conducted to measure the association between circumcision status and infection with HIV-1 among men with genital ulcer disease. Eight hundred and ten men participated in the study, of whom 190 (23%) were HIV-1-positive. A logistic regression model adjusted for behavioral and historical showed that HIV-1 positivity was independently associated with being uncircumcised (adjusted odds ratio [OR], 4.8; 95% confidence interval [CI], 3.3-7.2) and with a history of urethral discharge (adjusted OR, 2.0; 95% CI, 1.4-2.8). This association could not be explained by measures of sexual exposure to HIV-1 among this population. Male circumcision should be considered as an intervention strategy for AIDS control.
OKOTH PROFOGENDOHASTINGW. ""Land tenure, agrarian legislation and environmental management systems"; in Bakama, R. J. (Ed.) Land Tenure and Sustainable Land Use (Chapter 2) KIT Bulletin 221, The Netherlands.". In: Cent. Afri. J. Pharm.Sci. 5(3): 60-66. Cent. Afri. J. Pharm.Sci. 5(3): 60-66; 1994. Abstract
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
RAI MRVYASYASHWANT. "Law and Development in the Third World, pp. 614 (Co-editor & Contributor, Faculty of Law, University of Nairobi.". In: Journal of the Kenya National Academy of Science Nairobi 20-43.; 1994. Abstract
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RAI MRVYASYASHWANT. "Law and Development in the Third World, pp.614 (Co-editor & Contributor, Faculty of Law, University of Nairobi,.". In: Journal of the Kenya National Academy of Science Nairobi 20-43.; 1994. Abstract
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DOROTHY MRSOMOLLO. "Law, Ethics and HIV: Kenya.". In: J Infect Dis. 1992 Aug;166(2):359-64. Earthscan, London. 978-1-84407-469-3 (*); 1994. Abstract

Division of Bacterial and Mycotic Diseases, Centers for Disease Control, Atlanta, GA 30333. An epidemic of meningococcal disease occurred in Nairobi, Kenya, during 1989, outside the "meningitis belt" of sub-Saharan Africa. About 3800 cases occurred between April and November (250/100,000 population). The case-fatality rate was 9.4% among hospitalized patients. Areas that included Nairobi's largest slums had particularly high attack rates. The epidemic displayed an unusual age distribution, with high attack rates among those 20-29 years old. A vaccination campaign was conducted. By early January, the weekly case count had fallen to 25 from a high of 272 (in September). A case-control study estimated the vaccine efficacy to be 87% (95% confidence interval, 67%-95%). A model estimated that the vaccination campaign reduced the number of cases by at least 20%. Multilocus enzyme electrophoretic typing demonstrated that the strain responsible for this large epidemic is closely related to strains that caused other recent epidemics, documenting further spread of what may be a particularly virulent clonal complex of group A Neisseria meningitidis.

OKECH MROWITIMAURICED. "'Law, Ideology and Development: Dialectics or Eclectics at Play?', in Yash Vyas, Kivutha Kibwana, Okech-Owiti and Smokin Wanjala (eds): Law and Development in theThird Wolrd (Nairobi, Faculty of Law, University of Nairobi).". In: Victoria Walter and Debbie Betts (eds), Safeguarding Human Rights in Eastern Africa (FES, Kampala), 77. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1994. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
OKECH MROWITIMAURICED. "'Learning as a Participatory Process in Kenya: One Experience in University Pedagogy', UNLJ NO. 1, 1994 152-159.". In: Victoria Walter and Debbie Betts (eds), Safeguarding Human Rights in Eastern Africa (FES, Kampala), 77. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1994. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
WAIRIMU PROFKIBERALUCY. "Literacy and Post Literacy Print and Visual Materials with a Gender Perspective,.". In: UNESCO sub-regional seminar Arusha, Tanzania.- 3 rd to 13 th October, 1994. AIDS 24(6):891-7; 1994. Abstract
  
SHEM MRON&#39;GONDO. "LL.M Course Work Essay (1994), Humanitarian law and the International Protection of victims of Armed Conflicts.". In: International Journal of BiochemiPhysics Vol. 6 & 7, (Nos. 1 & 2) : 45 . Jane A. Otadoh,, Sheila A. Okoth, James Ochanda, James P. Khaindi; 1994. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Hepatocellular carcinoma results when cancerous cells are localized in the liver. It is distributed globally with high prevalence in sub-Saharan African, southern Asia, China and Japan. Diagnosis is experimental and in many cases inaccurate due to unreliability of markers. Prognosis is poor and the cost of treatment prohibitive. Conventional radiation and chemotherapy lead to loss of hair, fertility and general weakening of the body`s immune system increasing a patient`s risk to infection. These observations underscore the need for improved, or additional methods of cancer diagnosis and management. We investigated the effect of polysaccharide rich Pleurotus pulmonarius fruit body extracts on progression of chemically induced hepatocellular carcinoma in CBA mice. Addition of Pleurotus pulmonarius extracts in diet delayed progression of carcinogenesis suggesting   that these extracts may be useful as   adjuvants to conventional cancer therapies.   Key words: carcinogenesis; mice; mushroom extracts; pleurotus pulmunarius   Corresponding author: Ms Carolyne Wasonga, Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi,  Kenya. E-mail: carox27@yahoo.ca     Charles O.A. Omwandho, Susanne E. Gruessner, John Falconer, Hans-R Tinneberg, Timothy K. Roberts. IS OVINE PLACENTAL IGG TOXIC TO HUMAN PERIPHERAL BLOOD NATURAL KILLER CELLS?
JAMES PROFODEK. ""Lome IV: Dynamic or Static Improvement on the Previous conventions? The Sub-Saharan Africa Perspective" 27 Comparative and International Law Journal of Southern Africa at 164-198.". In: Paper presented at the WIPO High Level Forum on IP Policy and Strategy, Tokyo . Prof. James Otieno-Odek; 1994. Abstract
J. O. Midiwo, A. Yenesew, B. F. Juma, S. Dereses, J. A. Ayoo, A. Aluoch and S. Guchu There are several described medicinal plants in Kenya from a flora of approximately 10,000 members. Strong cross-medical information from the 42 ethnic groups points to the high potential of some of these species. The Myrsinaceae are well established ethno-anthelmintics and anti-bacterials. They are harbingers of long alkyl side chain benzoquinones which clearly have a protective function from their histochemical disposition. The main benzoquinone in the sub-family Myrsinodae is embelin while for the Maesodae it is maesaquinone together with its 5-acetyl derivative; the distribution of these benzoquinones by their alkyl side chain length or the presence/absence of a 6-methyl group is in accord with morphological sub-family de-limitation. The benzoquinones showed anti-feedant, anti-microbial, phytotoxic, acaricidal, insecticidal and nematicidal activity. Many other benzoquinones of medium and minor concentration were also isolated and characterised. Some plants belonging to the Polygonaceae which are widely used as ethno-anthelmintics have been studied. The common anthelmintic anthraquinones were obtained from all five Rumex species while the naphthalenic acetogenin derivative, nepodin was more selectively distributed. The leaf of Polygonum senegalense is up to 17% surface exudate; about thirteen non polar flavonoid derivatives (chalcones, dihydrochalcones, flavanones and a flavone) have been isolated from it. From the internal aerial tissues of this plant, the major flavonoids were common flavonoids, quercetin, kaempferol, luteolin and their glycosides. The only unique compound isolated from this plant was 2prime-glucosyl-6prime-hydroxy-4prime-methoxydihydrochalcone whose aglycone, uvangolatin is part of the exudate mixture. Other leaf exudate plants studied include the stomach-ache medicine, Psiadia punctulata (Compositae) from which novel methylated flavonoids, kaurene and trachyloban diterpenes have been found
N PROFLULEGODFREY, OTIENO PROFOGUTUELLY. "Lule GN, Obiero ET, Ogutu EO.Factors that influence the short term outcome of upper gastrointestinal bleeding at Kenyatta National Hospital. East Afr Med J. 1994 Apr;71(4):240-5.". In: East Afr Med J. 1994 Jan;71(1):44-8. Journal of British Ceramic Transactions, 99 [5], 206-211.; 1994. Abstract
Between April 1990 to January 1991, a prospective study of 97 consecutive patients admitted to the medical wards of Kenyatta National Hospital with upper gastrointestinal haemorrhage was done. All the patients studied under went upper gastrointestinal endoscopy within 24 hours of presentation and a positive endoscopic diagnosis was possible in 90 (93%) of the patients studied. The leading causes of bleeding were oesophageal varices in 34 (35%) patients, duodenal ulceration in 17 (17.5%) patients, and superficial inflammatory lesions in 17 (17.5%) patients. 17 (17.5%) patients had multiple lesions with superficial inflammation and oesophageal varices as the commonest combination. In 86 (88%) patients, bleeding settled on simple conservative measures which included intravenous fluids, blood transfusion and antacids. Further haemorrhage was observed in 11 (11.3%) patients. Tachycardia (> 100/minute), hypotension (systolic BP < 100mm Hg) and low haemoglobin (< 8 g/dl) at admission were all correlated with a poor outcome. Variceal bleeding had the worst prognosis and the overall mortality rate was 5%.
N PROFLULEGODFREY, OTIENO PROFOGUTUELLY. "Lule GN, Obiero ET, Ogutu EO.Factors that influence the short term outcome of upper gastrointestinal bleeding at Kenyatta National Hospital. East Afr Med J. 1994 Apr;71(4):240-5.". In: East Afr Med J. 1994 Jan;71(1):44-8. test; 1994. Abstract

Between April 1990 to January 1991, a prospective study of 97 consecutive patients admitted to the medical wards of Kenyatta National Hospital with upper gastrointestinal haemorrhage was done. All the patients studied under went upper gastrointestinal endoscopy within 24 hours of presentation and a positive endoscopic diagnosis was possible in 90 (93%) of the patients studied. The leading causes of bleeding were oesophageal varices in 34 (35%) patients, duodenal ulceration in 17 (17.5%) patients, and superficial inflammatory lesions in 17 (17.5%) patients. 17 (17.5%) patients had multiple lesions with superficial inflammation and oesophageal varices as the commonest combination. In 86 (88%) patients, bleeding settled on simple conservative measures which included intravenous fluids, blood transfusion and antacids. Further haemorrhage was observed in 11 (11.3%) patients. Tachycardia (> 100/minute), hypotension (systolic BP < 100mm Hg) and low haemoglobin (< 8 g/dl) at admission were all correlated with a poor outcome. Variceal bleeding had the worst prognosis and the overall mortality rate was 5%.

OKECH MROWITIMAURICED. "Labour Law and Relations.". In: Chapter 3. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1993. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
OKECH MROWITIMAURICED. "'Labour Laws', ibid.". In: Chapter 3. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1993. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
O PROFNYAMBOKISAAC. "The late Proterozoic Yatta Shear Zone: A possible lateral ramp extending across the Kenya Rift.". In: In Opiyo-Aketch (Editor): Proceedings of the 5th Conference of the Geology of Kenya. Geological Society of Kenya Publication. 69-77. Wiley Interscience; 1993. Abstract
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OKECH MROWITIMAURICED. "'Law of Contract', in Friedrich Ebert Foundation and Central Organisations of Trade Unions: The Industrial Court: A Course Book for Trade Unionist (Nairobi, FEF/COTU) Chapter 2.". In: Volume XXVI, No.1. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1993. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
OKECH MROWITIMAURICED. "The Law Relating to Associations: A Reference Summary.". In: Chapter 3. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1993. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
MWAGIRU PROFMAKUMI. "The Legal Milieu of the Environmentt:An Ovwerview.". In: Paradigms, Vol. 7, No. 1. University of Nairobi; 1993. Abstract
Kent papers in POlitics and International Relations, Series 4, No. 4.
ACHIENG DRODUMAJEMIMAH. "Leke, R.J.I.; Oduma, J.A.; Bassol-Mayagoita, S.; Bacha, A.M. & Grigor, K.N. (1993). Regional and Geographical variations in infertility: Effects of environmental, cultural and socioeconomic factors. Environ. Health Persp. Suppls. 101 (Suppl 2): 73-80.". In: Proceedings of 1st Pan-African Conference on biochemistry and molecular biology,Nairobi, Kenya. Douglas McLean Publishing; 1993. Abstract
This publication bring together upto 15 papers presented at the inagural conference of the world Association of Sign Language Interpreters by experts form around the globe. the pares highlight the importance of of worjing together and sharing a global responsibility for the development of interpreting services worldwide. This is a valuable resource for all sign language interpreters, students and interpreter trainers, and contains much to interest those who wish to know more about the situation of Sign Language interpratation form an internation perspective.
ELIZABETH GATUNGO. "Les fautes servent ." La Voix du CEFRUNA; 1993. Abstract
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W. PROFNZOMOMARIA. "Let us Together rebuild the Temple.". In: paper presented at the launching of the book They've Destroyed the Temple. Longman, Nairobi, at K.I.C.C., Nairobi, July.; 1993. Abstract

Journal of Eastern African Literary and Cultural Studies

W. PROFMWANGOMBEAGNES. "Level of seed-borne Colletotrichum lindemuthianum on common bean cv. Rosecoco - GLP2 from small scale farmers in Kenya, African Crop Science Conference Proceedings, Kampala 14-18 June 1993. PP 260-262.". In: African Crop Science Conference Proceedings, Kampala 14-18 June 1993. PP 260-262. J Hum Ecol, 26(3): 163-173 (2009).; 1993. Abstract
Fusarium wilt caused by Fusarium udum Butler, is an economically important disease of pigeonpea (Cajanus cajan (L.) Mill). Information on the mechanisms of resistance to this disease in pigeonpea is limited. To study the role of vascular occlusion in wilt resistance, isolates of F.udum were inoculated onto resistant and susceptible varieties of pigeonpea and observed under light and transmission electron microscopes. The presence of F. udum in wilt susceptible plants was characterized by mycelia and conidia in the xylem vessels, plugging in some vessels, disintegration of xylem parenchyma cells in the infected areas, and the formation of cavities due to heavy colonization in the pith cortex vascular bundle. Resistance to F. udum in the roots and stems of wilt resistant plants was associated with low fungal colonization and high occlusion due to tyloses and gels in the xylem vessels. There were significant differences (P = 0:05) in the number of xylem vessels occluded by tyloses in resistant and susceptible plants with a maximum of 22.5% and 8.0% occlusion, respectively. It is probable that tyloses and gels formed as a result of F. udum interaction in wilt resistant plants are part of a resistance mechanism. Key words: Fusarium wilt,cajanus cajan, resistance, tylose, vascular occlusion
STUART DRGONTIERCHRISTOPHER. "Lin HX, Gontier C, Saron MF, Perrin P. A new immunostimulatory complex (PICKCa) in experimental rabies: antiviral and adjuvant effects.Arch Virol. 1993;131(3-4):307-19.". In: Arch Virol. 1993;131(3-4):307-19. uon press; 1993. Abstract
Rabies Unit, Institut Pasteur, Paris, France. The activity of an immunostimulatory complex (PICKCa) which is widely used against several human diseases in China was tested in experimental rabies prophylaxis. PICKCa protected mice against peripheral infection with both fixed and wild rabies strains. It also enhanced the protective activity of an experimental rabies vaccine injected either before or after rabies infection. PICKCa enhanced both non-specific immune responses and specific immunity including antibody production and cell mediated immunity as assessed by interleukin-2 production.
KIIRU PROFMUCHUGUDH. "Literary Journals,.". In: Wajibu 14.1. Philosophical Issues Invoked by Shona People; 1993. Abstract

Literary scholars in Kenya have recognised that oral literature is a cultural heritage worth preserving and accessing. To this end, they have used traditional information to good effect. In today

SHEM MRON&#39;GONDO. "LL.M Course Work Essay (1993), University of Nairobi. The individual as a Subject or Object of International Law.". In: International Journal of BiochemiPhysics Vol. 6 & 7, (Nos. 1 & 2) : 45 . Jane A. Otadoh,, Sheila A. Okoth, James Ochanda, James P. Khaindi; 1993. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Hepatocellular carcinoma results when cancerous cells are localized in the liver. It is distributed globally with high prevalence in sub-Saharan African, southern Asia, China and Japan. Diagnosis is experimental and in many cases inaccurate due to unreliability of markers. Prognosis is poor and the cost of treatment prohibitive. Conventional radiation and chemotherapy lead to loss of hair, fertility and general weakening of the body`s immune system increasing a patient`s risk to infection. These observations underscore the need for improved, or additional methods of cancer diagnosis and management. We investigated the effect of polysaccharide rich Pleurotus pulmonarius fruit body extracts on progression of chemically induced hepatocellular carcinoma in CBA mice. Addition of Pleurotus pulmonarius extracts in diet delayed progression of carcinogenesis suggesting   that these extracts may be useful as   adjuvants to conventional cancer therapies.   Key words: carcinogenesis; mice; mushroom extracts; pleurotus pulmunarius   Corresponding author: Ms Carolyne Wasonga, Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi,  Kenya. E-mail: carox27@yahoo.ca     Charles O.A. Omwandho, Susanne E. Gruessner, John Falconer, Hans-R Tinneberg, Timothy K. Roberts. IS OVINE PLACENTAL IGG TOXIC TO HUMAN PERIPHERAL BLOOD NATURAL KILLER CELLS?
W. PROFMAKAWITIDOMINIC. "Lomo PO, Makawiti DW, Konji VN.Respiratory activity of isolated liver Mitochondria following Trypanosoma congolense infection in rabbits: the role of thyroxine. Comp Biochem Physiol B. 1993 Jan;104(1):187-91.". In: Comp Biochem Physiol B. 1993 Jan;104(1):187-91. Groebner-Bases-Bibliography-RICAM; 1993. Abstract
The effect of trypanosome infection on rabbit liver mitochondrial oxidative phosphorylation was investigated, with and without thyroxine replacement. 2. State 3 respiration, respiratory control ratio (RCR) and ADP/O ratio were significantly reduced in mitochondria from trypanosome-infected animals whereas there was no change in state 4 respiration. 3. State 3 respiration, RCR and ADP/O ratio were not significantly altered in trypanosome-infected animals given thyroxine replacement therapy. 4. Trypanosome infection leads to impairment of mitochondrial integrity, apparently through lowered thyroxine levels. Replacement of thyroxine therefore sustains optimal mitochondrial respiratory activity.
O PROFNYAMBOKISAAC. "Lake Turkana area: Tectonics and geology.". In: In Kenya from Space. CREDU, France. East African Educational Publishers. 96-99. Nairobi. Wiley Interscience; 1992. Abstract
n/a
OKOTH PROFOKOMBODUNCAN. "Language Education Improvement and the Creation of Language Related Careers in Kenya" In K.R. (ed.), Employment and Education in Kenya: Strategies and Opportunities for Development. Nairobi: Professors World Peace Academy.". In: In Southern African Review of Education, Vol.4, pp 5-10. CIGR Electocic Journal; 1992. Abstract
isolated from preterm neonates during the outbreak of gastroenteritis in hospital in Nairobi, Kenya, were resistance to trimethoprin-sulfathoxaxole, Chloramphenicol, oxytetracycline and ampicilin, but only a few strains were resistant to cefazolin, cefamandole, cefataximine, amikacin and nalidixic acid. Fourteen different antimicrobial resistance patterns were observed in the 229 strains of E.coli analyzed. Eighty-two percent of the EPEC strains belonged to two resistance patterns. There was no consistent relationship between palsmid profile group and antimicrobial resistance pattern, although one resistance pattern was more frequently observed in EAF-positive strins belonging to the dominant plasmid profile group. Nine percent of the EPEC strins were resistant to gentamicin compared to 37% in the non-EPEC group. No correlation was observed between administration of gentamicin and percentage of resistant strains isolated. None of the nine neonates receiving gentamicin died during the outbreak. Gentamicin resistance was observed in E.coli strains from six out of these nine neonates. Five out of fourteen neonates who received other antimicrobials, or no antibiotic at all, died. Key words: Enteropathogenic Escherichia Coli; antimicrobial resistance;
K. DRMANGOLIMAURICE. "Lee. K.V.. Mangoli. M.K.. Kirn. J.B., Kirn, J.B. . and Park. Y.M. "" A Three Level Hierarchical Approach lorOptimal Reactive power Planning IEEProc., C. Cat. Trans. and Distrib. 1992.". In: Electric Power Systems Research, Vol. 26, pp. 1-10, 1993. I.E.K Internatioanl Conference l; 1992. Abstract
This paper develops an improved real and reactive power control technique using linear programming (LP) for an integrated power system. The problem is decomposed into two subproblems comprising real (P) and reactive power (Q) modules, and, using a unified approach, the real power generation, voltage magnitude, and transformer tap settings are optimized. The objective function is the fuel cost which is minimized in both the P and Q modules, subject to the operating constraints. The P-Q decomposition combined with the LP formulation improve the computation speed. The paper has another advantage of using the same cost objective function for both modules, unlike other conventional methods which use the power loss function for the Q module. The LP formulation is used for both the P and Q optimization modules, utilizing the revised simplex method which is normally available in a mainframe computer.
K. DRMANGOLIMAURICE. "Lee. K.Y.. Mangoli, M.K., Kirn, J.B., Kirn, J.B. , and Park. Y.M. "" An Operational Planning Tool for Real and Reactive Power Control"", IEE Proc., C.Cen., Trans. and Distrih. 1992.". In: Electric Power Systems Research, Vol. 26, pp. 1-10, 1993. I.E.K Internatioanl Conference l; 1992. Abstract
This paper develops an improved real and reactive power control technique using linear programming (LP) for an integrated power system. The problem is decomposed into two subproblems comprising real (P) and reactive power (Q) modules, and, using a unified approach, the real power generation, voltage magnitude, and transformer tap settings are optimized. The objective function is the fuel cost which is minimized in both the P and Q modules, subject to the operating constraints. The P-Q decomposition combined with the LP formulation improve the computation speed. The paper has another advantage of using the same cost objective function for both modules, unlike other conventional methods which use the power loss function for the Q module. The LP formulation is used for both the P and Q optimization modules, utilizing the revised simplex method which is normally available in a mainframe computer.
JAMES PROFODEK. "LL.B. Thesis. 1992, Rigit and Flexible Constitutions. A Consideration of Theory in the Light of the Kenyan Experience.". In: Paper presented at the WIPO High Level Forum on IP Policy and Strategy, Tokyo . Prof. James Otieno-Odek; 1992. Abstract
J. O. Midiwo, A. Yenesew, B. F. Juma, S. Dereses, J. A. Ayoo, A. Aluoch and S. Guchu There are several described medicinal plants in Kenya from a flora of approximately 10,000 members. Strong cross-medical information from the 42 ethnic groups points to the high potential of some of these species. The Myrsinaceae are well established ethno-anthelmintics and anti-bacterials. They are harbingers of long alkyl side chain benzoquinones which clearly have a protective function from their histochemical disposition. The main benzoquinone in the sub-family Myrsinodae is embelin while for the Maesodae it is maesaquinone together with its 5-acetyl derivative; the distribution of these benzoquinones by their alkyl side chain length or the presence/absence of a 6-methyl group is in accord with morphological sub-family de-limitation. The benzoquinones showed anti-feedant, anti-microbial, phytotoxic, acaricidal, insecticidal and nematicidal activity. Many other benzoquinones of medium and minor concentration were also isolated and characterised. Some plants belonging to the Polygonaceae which are widely used as ethno-anthelmintics have been studied. The common anthelmintic anthraquinones were obtained from all five Rumex species while the naphthalenic acetogenin derivative, nepodin was more selectively distributed. The leaf of Polygonum senegalense is up to 17% surface exudate; about thirteen non polar flavonoid derivatives (chalcones, dihydrochalcones, flavanones and a flavone) have been isolated from it. From the internal aerial tissues of this plant, the major flavonoids were common flavonoids, quercetin, kaempferol, luteolin and their glycosides. The only unique compound isolated from this plant was 2prime-glucosyl-6prime-hydroxy-4prime-methoxydihydrochalcone whose aglycone, uvangolatin is part of the exudate mixture. Other leaf exudate plants studied include the stomach-ache medicine, Psiadia punctulata (Compositae) from which novel methylated flavonoids, kaurene and trachyloban diterpenes have been found
ODERA PROFALILAPATRICK. "'Local Level Institutions of Participation in a Changing Political and Economic Development Environment - The Kenyan Experience'. Paper presented to the IDE Workshop on African Political Economy in Transition, Tokyo, Japan, March 1992.". In: The Development of the National Economy Colourprint Ltd. Nairobi, 1993. International Union of Crystallography; 1992. Abstract
Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing cord to the left with no dye being seen beyond T3. Thoracic spine decompressive laminectomy was performed on 1st January 1996 at Nairobi West Hospital extending from T3 to T6 level, which revealed a fibrous haemorrhagic tumour. Histology showed meningioma (mixed fibrous type and meningoepitheliomatous type) with many psammoma bodies. She had a stormy post-operative period, with infection and wound dehiscence. This was treated with appropriate antibiotics and wound care. She was eventually rehabilitated and was able to walk with the aid of a walking frame because of persistent spasticity of right leg. She was seen once as an outpatient by author on 6th July 1996, she was able to use the walking frame, but the right leg was still held in flexion deformity at the knee. She was thus referred to an orthopaedic surgeon for possible tenotomy. She was able to resume her studies at the University ambulating using a wheel chair and walking frame. She presented with worsening of symptoms in 2001 (five years after her first surgery). MRI scan thoracic spine revealed a left anterolateral intradural lesion extending from T3 to T5 vertebral body level compressing and displacing the spinal cord. She had a repeat surgery on 6th March 2001 at Kenyatta National Hospital; spastic paraparesis and urinary incontinenece persisted. She also developed bed sores and recurrent urinary tract infections. She was followed up by the author and other medical personnel in Mwea Mission Hospital where she eventually succumbed in 2005, nine years after her first surgery. This case is presented as a case of incompletely excised spinal meningioma to highlight some of the problems of managing spinal meningiomas when operating microscope and embolisation of tumours are not readily available. Also the family experienced financial constraint in bringing the patient for regular follow-up, and getting access to appropriate antibiotics, catheters and urine bags.
N PROFOGOLAELIJAHS, OTIENO PROFOGUTUELLY. "Lore W, Muita AK, Ogola ES.The efficacy and tolerability of enalapril–hydrochlorothiazide combination as a first line therapy in black patients with mild to moderate arterial hypertension: a clinical study in Kenya.East Afr Med J. 1992 Jan;69(1):18-21.". In: East Afr Med J. 1992 Jan;69(1):18-21. Kisipan, M.L.; 1992. Abstract
The study aimed at evaluating tolerability and efficacy of the combination enalapril 20 mg with hydrochlorothiazide 12.5 mg (co-renitec) as first line therapy in black patients with mild to moderate primary hypertension. Fifty patients completed a twelve weeks of open clinical study preceded by two weeks of washout period. They were evaluated every four weeks and haematological, biochemical urine microscopy and electrocardiographic tests were undertaken before the start and after the completion of study. Pre-treatment values of mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 172.16 mm hg (+/- 20.41) and 104.38 mm hg (+/- 7.339) respectively. The usual daily dosage was one tablet which was increased to two after eight weeks in case the DBP was not normalized, i.e. less than or equal to 95 mm hg. In 44 (88%) patients, the DBP was normalised at the end of the study period; three patients (6%) were resistant to treatment and another three (6%) exhibited labile response to the treatment. Clinical tolerance was considered to be very good with only five episodes of headache, backache and anxiety, probably not related to the test drug. Biological tolerance was excellent: there was no change in the haematologic parameters; there was a decrease of 5% in mean blood urea, of 9% in the mean serum creatinine and of 4% in the mean serum uric acid and a 5% increase in plasma potassium from 3.99 to 4.28 mmol/l.(ABSTRACT TRUNCATED AT 250 WORDS)
N PROFOGOLAELIJAHS, OTIENO PROFOGUTUELLY. "Lore W, Muita AK, Ogola ES.The efficacy and tolerability of enalapril–hydrochlorothiazide combination as a first line therapy in black patients with mild to moderate arterial hypertension: a clinical study in Kenya.East Afr Med J. 1992 Jan;69(1):18-21.". In: East Afr Med J. 1992 Jan;69(1):18-21. Journal of British Ceramic Transactions, 99 [5], 206-211.; 1992. Abstract
The study aimed at evaluating tolerability and efficacy of the combination enalapril 20 mg with hydrochlorothiazide 12.5 mg (co-renitec) as first line therapy in black patients with mild to moderate primary hypertension. Fifty patients completed a twelve weeks of open clinical study preceded by two weeks of washout period. They were evaluated every four weeks and haematological, biochemical urine microscopy and electrocardiographic tests were undertaken before the start and after the completion of study. Pre-treatment values of mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 172.16 mm hg (+/- 20.41) and 104.38 mm hg (+/- 7.339) respectively. The usual daily dosage was one tablet which was increased to two after eight weeks in case the DBP was not normalized, i.e. less than or equal to 95 mm hg. In 44 (88%) patients, the DBP was normalised at the end of the study period; three patients (6%) were resistant to treatment and another three (6%) exhibited labile response to the treatment. Clinical tolerance was considered to be very good with only five episodes of headache, backache and anxiety, probably not related to the test drug. Biological tolerance was excellent: there was no change in the haematologic parameters; there was a decrease of 5% in mean blood urea, of 9% in the mean serum creatinine and of 4% in the mean serum uric acid and a 5% increase in plasma potassium from 3.99 to 4.28 mmol/l.(ABSTRACT TRUNCATED AT 250 WORDS)
N PROFOGOLAELIJAHS. "LORE W; MUITA A.K; OGOLA E.N; Efficacy and tolerability of Enalapril hydrochlorothiazide combination as first line therapy in essential arterial hypertension in Blacks, a Clinical Trial Kenya. East Africa .Med J.69: 18, 1992.". In: East Africa .Med J.69: 18, 1992. Kisipan, M.L.; 1992. Abstract

Sixty patients with Diastolic Blood Pressure (DBP) of 100-110mmHg matched for age, sex and Bp levels were randomly assigned to propranolol 80mg daily or Hydroflumethiazide (HFM) 50mg daily. HFM causes a significant reduction in systolic blood pressure (SBP) and DBP within 4 weeks compared both with baseline and propranolol (SBP 143.7 +/- 12.3 vs 158.1 +/- 10.9mmHg, P < 0.05; DBP 92.0 +/- 4.5 vs 102.4 +/- 5.1mmHg, P < 0.05), (SBP 143.7 +/- 12.2 vs 152 +/- 11.0mmHg P < 0.05; DBP 92.0 +/- 4.5 vs 101.1 +/- 6.1mmHg, P < 0.05), respectively. Propranolol produced no significant difference from the baseline at 4 weeks (SBP 152.0 +/- H.0 vs 154.1 +/- 11.5mmHg NS; DBP 101.1 +/- 6.1 vs 102.2 +/- 5.6mmHg, NS). Reduction in BP by HFM was maintained after 8 and 12 weeks with further reduction but which did not achieve statistical significance. Increased dose of propranolol (160mg daily) after 4 weeks caused significant reduction in BP by 8 week (SBP 146.8 +/- 11.8 vs 152.0 +/- 11.0mmHg, P < 0.05; DBP 95.9 +/- 4.4 vs 101.1 +/- 6.1mmHg P < 0.05), which was maintained upto 12 weeks. The values however remained higher than in the HFM group. More patients in the HFM group achieved target BP (< 140/90), SBP 53.8% vs 29.6% P < 0.05, DBP 69.2% vs 14.8% P < 0.01. Incidence of side effects was similar and will be discussed. Thiazides are superior to B'blockers as initial monotherapy in black hypertensives.

Mungania G. "Language Policy in Kenya: Prospects and Retrospects.". In: 22nd Annual Conference on African Linguistics. University of Nairobi, Kenya; 1991.
N. DRNJENGAHELLEN. "Low Pressure and Salt Effect on the Ethanol-Water Vapour-Liquid Equilibrium.". In: Ph.D. Thesis University of Wales. Elsevier; 1991.
E. DRKAPULEDANIEL. "Laevelling Techniques II.". In: Nairobi University Press. RIVERBRROKS COMMUNICATIONS; 1991. Abstract
PMID: 614126 [PubMed - indexed for MEDLINE]
OBIMBO DRLAMUKAPETER. "Lamuka P.O., Sunki G.R., Rao D.R. and Shackelford L.A. 1991. Effects of Streptococcus thermophilus whey Fermented an Low Dose Irradiation on Microbiological quality and Self Life of chicken Carcasses. Abstract IFT Annual meeting. California. June 14 .". In: Eur J. Biochem. Heinrich Boll Foundation.; 1991. Abstract
Thymidine kinase is an enzyme involved in DNA precursor metabolism and DNA replication. The synthesis of this enzyme is highly regulated during the cell cycle and the activity of the enzyme is also regulated by feedback inhibition. Genes encoding thymidine kinase have been extremely useful as selectable markers for introducing DNA into a number of cells. In order to study cell cycle regulation of thymidine kinase, the gene which encodes this enzyme, as well as aspects of DNA replication in the ciliated protozoan Tetrahymena thermophila, we have purified thymidine kinase from Tetrahymena. Two forms of thymidine kinase with native molecular masses of 59 kDa and 80 kDa have been identified and purified 6800- and 4600-fold, respectively. The 59-kDa enzyme, a homodimer of 30-kDa subunits, has been purified to near homogeneity and polyclonal antibodies have been raised against the 30-kDa subunit. Serological studies indicate that the two enzymes are antigenically distinct. The antibody against the Tetrahymena protein cross-reacts with a polypeptide in Chinese hamster ovary (CHO) cell extracts of 26 kDa which corresponds to the reported size of Chinese hamster thymidine kinase protein.
KONYIMBIH DRTOM. "LAND DEALINGS IN KENYA.". In: KLB. WFL Publisher; 1991. Abstract
PREAMBLE   In   The Act of Parliament gives wide powers to Land Control Boards established in Land Control Agricultural Areas (Section 5 Cap 302) to hear applications brought to them (through the District Land Registrars) and to consider the same under the criteria stipulated in the Act, with appeal procedures being also provided for in the same statute.   This paper analyses the administrative and circumstantial efficacy of controlling transactions in registered agricultural land as specified in section 6(1) of the Act. It uses the recent land control experiences of the Muhoroni Land Control Board in particular, and the decided court cases in general to analyze the operations of the Act in terms of its practical, legal,social, economic and procedural limitations.   The paper concludes that despite the seemingly good intentions, the forty year old statute should substantially be reviewed in order to be a useful tool of rural land policy.  In the event that it is interfering with private transactions in land in circumstances where a number of statutes also exert some controlling influence on agricultural land in Kenya, Parliament may now consider repealing the Act altogether.
KONYIMBIH DRTOM. "LAND RIGHTS MATRIX: Developing Land Tenure Data for Kenya.". In: KLB. WFL Publisher; 1991. Abstract
The government of   This study is a contribution towards that outcome and is meant to examine the general land use structure, land tenure conditions and their interrelations in a matrix of the user-rights scenario that will enable the government to develop a useful data base.   Four of the largest nomadic pastoralist ethnic communities were surveyed in northern Kenya, the Somali, Gabra, Rendille and the Borana in Wajir and Marsabit districts (see Map 2) in locations where they predominantly live.   Against a backdrop of extensive and intensive literature review, a field work survey was carried out using convenience sampling.  Information was recorded in semi-structured questionnaires and interview schedules, followed by focus group discussions and informant interviews.   The analysis shows that land rights, land use and livestock keeping are closely intertwined and form the economic, social and cultural basis of nomadic pastoralist livelihoods.   The detailed labour management requirement of each livestock type and age is well planned at family and community level.  Therefore, the pasture, water, veterinary and security needs of each species of livestock must be coordinated carefully in order to optimize on the use of land resources both at the settlement camps and at the grazing camps.   Land is categorized depending on the type of vegetation that it produces for dry season or wet season grazing and browsing.  Livestock, livelihood and land use therefore require flexibility and movement over large distances in order to pasture and water both the animal and human populations in an environment that is restricted by aridity, insecurity and soil infertility.   Access to suitable land means access to suitable pasture and this enables both livestock and human reproduction.  This is determined by ethnic community membership even when they own all the livestock and some of the water points (boreholes) individually.   Some more work however, remains to be done in tracking the land rights transitions over time and how these rights will respond to population pressure in these nomadic pastoralist areas in the near and distant future.  
KONYIMBIH DRTOM. "Land Settlements, Land Reforms and the historical causes of land grievances in Kenya.". In: KLB. WFL Publisher; 1991. Abstract
The objective of this paper is to provide a general review of the historical and statutory genesis of the present land grievances in European settlement on fertile agricultural land in Kenya consigned the indigenous Kenyans in those areas to marginal reserves that soon became overpopulated with the consequent decrease of land acreage per capita leading to resource conflicts.   With the coming of independence, a programme of land re-settlement was hurriedly designed for those who had been marginalized but this had a minimal effect on landlessness because it did not offer enough land (sold to the Kenya Government by departing European settlers) for those who were landless. Those who obtained plots under the programme were saddled by loan repayment from the onset, on, at times very marginal unproductive land.   The policy of land adjudication, consolidation and registration meant to give proprietors indefeasible titles for greater productivity has not, after fifty years, had the economic impact earlier anticipated by its proponents. It has not stemmed landlessness as those with titles at times attempt to enforce their rights against family members whose ancestral rights could not have been recorded in the land registers. In a land-based agricultural country such as Kenya, the problem of landlessness is bound to increase (with increasing population and lack of off-farm economic opportunities) as resource competition increases leading to displacement and further land conflicts.   There is now a new opportunity to design and pass legislation that takes on board the socio-economic circumstances of the land tillers and that will protect multiple rights in periods of lack of alternative economic and social opportunities to guarantee some sort of beneficial access to land for the majority. It will be highly beneficial to these people if new legislations include a researched way of effectively communicating them to the rural population.   
KONYIMBIH DRTOM. "LAND TITLING IN SUB-SAHARAN AFRICA: Kenya.". In: KLB. WFL Publisher; 1991.
KONYIMBIH DRTOM. "Land, Governance and Poverty Alleviation in Kenya. Issues for the next millennium.". In: KLB. WFL Publisher; 1991. Abstract
This article investigates the forces leading to migration of husbands from rural Kenya, the economic situation and activities of wives with migrant husbands, receipt of remittances by wives and the possible influences on capital formation in rural Kenya, using the Nyeri district as a case study. Although the residual sample of rural wives whose husbands have migrated to urban areas in Kenya is small, the analysis of this sample highlights several important points worthy of investigation. It seems that rural husbands who migrate from rural Kenya have limited education and skills and are mostly pushed out of rural areas rather than pulled. The wives seem not to be empowered in relation to economic and family decisions-making. The husband and his relatives retain control of important economic and household decisions and this has negative impacts on agricultural productivity. The wives are hampered by their relative lack of access to agricultural extension officers, finance for farm investment and capital resources for use on their farm. Probit analysis suggests that the probability of a wife obtaining remittances from a migrant husband declines with the number of years of his absence and the age of the wife but increases with the number of her dependent children and whether or not she employs hired labour. Duration of migration is important in explaning the amount of remittances but not in explaining the likelihood of wives receiving remittances. Overall indications are that remittances are mostly motivated by altruism or social obligation of the migrant to his family. This study was limited by lack of resources but nonetheless provides useful pointers to further research.  
KONYIMBIH DRTOM. "Landholding and Ethics: Critical issues for Kenya.". In: KLB. WFL Publisher; 1991.
RAI MRVYASYASHWANT. ""Landlords, Tenants and the Law: There is Recourse to the Law".". In: Executive, Nairobi, 19-20 (February 1991).; 1991. Abstract
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O PROFNYAMBOKISAAC. "Large-scale variation in lithospheric structure along and across the Kenya rift.". In: KRISP Working Group Nature vol. 354.223-227. Wiley Interscience; 1991. Abstract
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"The Law Curriculum Development, the Kenyan Experience." G.K. Rukwaro & Kivutha Kibwana (eds); 1991. Abstract
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OYOO PROFWANDIGASHEM. "Lead Contamination in Street Soils of Nairobi City and Mombasa Island , Kenya.". In: Bull.Environ. Contamination and Toxicology;, 46: 782-789. Academic Press Elsevier. Int.; 1991. Abstract
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L DRLEGGEPATRICK. "Legge, P.L. & N.Opiyo-Akech, (1991): Structural environment of Gold Ore Deposits in Bondo-Asembo area, Western Kenya,.". In: Proceedings of 25 Years SGA Anniversary Meint, pp.461-464; A Balkema, Rotterdam. Heinrich Boll Foundation.; 1991.
B PROFOJWANGSHADRACK, OTIENO DRODAWAFRANCISXAVIER. "Lema VM, Ojwang SBO, Wanjala SHM Rupture of gravid uterus. E. Afr. Med. J. 1991: 68, 430.". In: E. Afr. Med. J. 1991: 68, 430. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1991. Abstract
A total of 105 patients were treated for ruptured gravid uteri at the Kenyatta National Hospital, Nairobi, Kenya, over a five year period, January, 1984 to December, 1988. During the same period, there were 44,156 deliveries, giving an incidence of uterine rupture of 1:425 deliveries. Of these, records for 95 patients were traced and analysed, and the results are presented here. Majority (61.0%) of these patients were aged less than 30 years, and 62.1% were gravida 5 or less. 54 (56.8%) of them had rupture of scarred uteri, 33 (34.7%) had spontaneous rupture, while 8 (8.4%) had traumatic rupture. 56 (59.0%) ruptured while at the Kenyatta National Hospital. Repair of the uterus without tubal ligation was the treatment offered to most of them, while total abdominal hysterectomy was rarely done. The perinatal case fatality rate was 60% and there were two maternal deaths giving a maternal case fatality rate of 2.1%. Factors associated with uterine rupture at the Kenyatta National Hospital are discussed, and possible ways of reducing the incidence suggested. PIP: Physicians treated 105 patients with uterine rupture at Kenyatta National Hospital (KNH) in Nairobi, Kenya between January 1984-December 1988. The ruptured gravid uterus incidence during the study period was 1:425. 56.8% of the mothers were between 20-29 years old. 62.1% were gravida 5. 21.1% had received no prenatal care. 59% ruptured at this hospital. Adequate labor monitoring would have prevented rupturing. 56.8% experienced at least 1 previous cesarean section (C-section). Only 2 women had had a classical C-section. Moreover 21.1% of mothers who had prenatal care at KNH underwent a previous C-section. Perhaps health workers did not evaluate these women properly. 74% of the mothers were at least 38 weeks gestation. 34.7% had a spontaneous rupture due to prolonged labor (12 hours). 8.4% experienced a traumatic rupture. 94.7% happened during labor. Most of the tears (51.6%) occurred along the lower anterior uterine segment primarily on the transverse or on a C-section scar. Surgeons were able to repair the uterus without tubal ligation in 47.4% of the cases. They could repair the uterus of 11.6%, but also had to perform a tubal ligation. They conducted a partial hysterectomy on 38% and total hysterectomy on 3.2%. 38.9% gave birth to their infants vaginally. 55.8% of the mothers gave birth to a stillborn infant. 35.8% of the infants were delivered in good condition and survived. 4.2% were in poor condition and survived and 4.2% were in poor condition and died. All the infants in the peritoneal cavity were already dead, but not all of those in the uterus died. The case fatality rate stood at 60%. 2.1% of the mothers died, all after surgery. 1 mother actually died of injuries from an earlier assault. In conclusion, C-section was the major predisposing factor. Ruptured gravida uteri continued to be a major obstetric problem in Kenya.
B PROFOJWANGSHADRACK, OTIENO DRODAWAFRANCISXAVIER. "Lema VM, Ojwang SBO, Wanjala SHM Rupture of gravid uterus. E. Afr. Med. J. 1991: 68, 430.". In: E. Afr. Med. J. 1991: 68, 430. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1991. Abstract
A total of 105 patients were treated for ruptured gravid uteri at the Kenyatta National Hospital, Nairobi, Kenya, over a five year period, January, 1984 to December, 1988. During the same period, there were 44,156 deliveries, giving an incidence of uterine rupture of 1:425 deliveries. Of these, records for 95 patients were traced and analysed, and the results are presented here. Majority (61.0%) of these patients were aged less than 30 years, and 62.1% were gravida 5 or less. 54 (56.8%) of them had rupture of scarred uteri, 33 (34.7%) had spontaneous rupture, while 8 (8.4%) had traumatic rupture. 56 (59.0%) ruptured while at the Kenyatta National Hospital. Repair of the uterus without tubal ligation was the treatment offered to most of them, while total abdominal hysterectomy was rarely done. The perinatal case fatality rate was 60% and there were two maternal deaths giving a maternal case fatality rate of 2.1%. Factors associated with uterine rupture at the Kenyatta National Hospital are discussed, and possible ways of reducing the incidence suggested. PIP: Physicians treated 105 patients with uterine rupture at Kenyatta National Hospital (KNH) in Nairobi, Kenya between January 1984-December 1988. The ruptured gravid uterus incidence during the study period was 1:425. 56.8% of the mothers were between 20-29 years old. 62.1% were gravida 5. 21.1% had received no prenatal care. 59% ruptured at this hospital. Adequate labor monitoring would have prevented rupturing. 56.8% experienced at least 1 previous cesarean section (C-section). Only 2 women had had a classical C-section. Moreover 21.1% of mothers who had prenatal care at KNH underwent a previous C-section. Perhaps health workers did not evaluate these women properly. 74% of the mothers were at least 38 weeks gestation. 34.7% had a spontaneous rupture due to prolonged labor (12 hours). 8.4% experienced a traumatic rupture. 94.7% happened during labor. Most of the tears (51.6%) occurred along the lower anterior uterine segment primarily on the transverse or on a C-section scar. Surgeons were able to repair the uterus without tubal ligation in 47.4% of the cases. They could repair the uterus of 11.6%, but also had to perform a tubal ligation. They conducted a partial hysterectomy on 38% and total hysterectomy on 3.2%. 38.9% gave birth to their infants vaginally. 55.8% of the mothers gave birth to a stillborn infant. 35.8% of the infants were delivered in good condition and survived. 4.2% were in poor condition and survived and 4.2% were in poor condition and died. All the infants in the peritoneal cavity were already dead, but not all of those in the uterus died. The case fatality rate stood at 60%. 2.1% of the mothers died, all after surgery. 1 mother actually died of injuries from an earlier assault. In conclusion, C-section was the major predisposing factor. Ruptured gravida uteri continued to be a major obstetric problem in Kenya.
N PROFKAMAUGEOFREY. "Levels of Mercury in water, fish, sediments and blood samples from different regions of Kenya", J. Biochemiphysics, 1, 9.". In: Proceedings of the KMRI/KETRI annual Medical Scientific Conference, Nairobi, Kenya 1993. Survey Review; 1991. Abstract
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B PROFOJWANGSHADRACK, OTIENO DRODAWAFRANCISXAVIER. "Lilian W, Nasah BI Leke RJI, Ojwang SBO Determinants of Perinatal Mortaligy Hour and Day of birth and method of delivery at the central maternity .". In: J. Obstet. Gyna East Afr. 10(2): 65 1992,. EM Ngatia, LW Gathece, FG Macigo, TK Mulli, LN Mutara, EG Wagaiyu.; 1991. Abstract

PIP: In this study, 273 university students (161 men and 112 women) were interviewed by means of a self-administered questionnaire to determine their knowledge, attitude, and practice concerning sexually transmitted diseases (STDs). The mean age of the men was 22.4 +or- 1.6 years and that of the women was 22.1 +or- 1.6 years. 97.4% of the students were sexually experienced. Knowledge of common STDs was high, but knowledge of their signs, symptoms, and consequences was low. 24.5% of the male and 3.7% of the female students had had an STD. The principal sources of information on STDs included books, films, and TV for 39.6% of the students and teachers for 16.8% of the students. Parents played a very minimal role. It is suggested that primary and secondary school students be taught about STDs as part of reproductive health education and that such education be continued at the college level in order to increase the awareness among young people. author's modified

B PROFOJWANGSHADRACK, OTIENO DRODAWAFRANCISXAVIER. "Lilian W, Nasah BI Leke RJI, Ojwang SBO Determinants of Perinatal Mortaligy Hour and Day of birth and method of delivery at the central maternity .". In: East Afr Med J. 1992 Sep;69(9):483-6. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1991. Abstract
An audit of 381 hysterectomies performed over a 5 year period (1986-1990) was carried out. In order to assess justification of the indication for hysterectomy pre-operative diagnoses were divided into two groups: those potentially confirmable by pathologic study and those not potentially confirmable by pathologic study. Out of the 273 cases studied in the first group, 246 (90.1%) were justified, while out of the 108 cases studied in the second group, 82 (75.9%) were justified. An overall 86% justification rate was observed. Adenomyosis as a histopathologic finding was seen more commonly in Asian than African patients (P < 0.005). Morbidity rate was 20% and there were no mortalities. The procedure in general was considered safe and justified
JOAB PROFBWAYOJOB. "Long distance truck drivers. 2:Knowledge and attitudes concerning sexually transmitted diseases and sexual behaviour. Bwayo JJ; Mutere AN; Omari MA; Kreiss JK; Jaoko W; Sekkade-Kigondu C; Plummer FA. East Afr Med J. 1991 Sep;68(9):714-9.". In: East Afr Med J. 1991 Sep;68(9):714-9. Asian Economic and Social Society; 1991. Abstract
The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. This cross-sectional study was conducted to measure the association between circumcision status and infection with HIV-1 among men with genital ulcer disease. Eight hundred and ten men participated in the study, of whom 190 (23%) were HIV-1-positive. A logistic regression model adjusted for behavioral and historical showed that HIV-1 positivity was independently associated with being uncircumcised (adjusted odds ratio [OR], 4.8; 95% confidence interval [CI], 3.3-7.2) and with a history of urethral discharge (adjusted OR, 2.0; 95% CI, 1.4-2.8). This association could not be explained by measures of sexual exposure to HIV-1 among this population. Male circumcision should be considered as an intervention strategy for AIDS control.
JOAB PROFBWAYOJOB. "Long distance truck-drivers: 1. Prevalence of sexually transmitted diseases (STDs). Bwayo JJ; Omari AM; Mutere AN; Jaoko W; Sekkade-Kigondu C; Kreiss J; Plummer FA. East Afr Med J. 1991 Jun;68(6):425-9.". In: East Afr Med J. 1991 Jun;68(6):425-9. Asian Economic and Social Society; 1991. Abstract
The factors responsible for the explosive spread of human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa continue to be identified and debated. One of the most controversial factors has been male circumcision. This cross-sectional study was conducted to measure the association between circumcision status and infection with HIV-1 among men with genital ulcer disease. Eight hundred and ten men participated in the study, of whom 190 (23%) were HIV-1-positive. A logistic regression model adjusted for behavioral and historical showed that HIV-1 positivity was independently associated with being uncircumcised (adjusted odds ratio [OR], 4.8; 95% confidence interval [CI], 3.3-7.2) and with a history of urethral discharge (adjusted OR, 2.0; 95% CI, 1.4-2.8). This association could not be explained by measures of sexual exposure to HIV-1 among this population. Male circumcision should be considered as an intervention strategy for AIDS control.
OTIENO PROFOGUTUELLY. "Lule G.N., Sang F., Ogutu E.O. Helicobacter Pylori in peptic ulcer disease. E. Afr. Med. J. 68: 324, 1991.". In: East Afr Med J. 1991 May;68(5):324-7. Journal of British Ceramic Transactions, 99 [5], 206-211.; 1991. Abstract
Department of Medicine, University of Nairobi. Sixty six patients with dyspeptic symptoms underwent upper gastrointestinal endoscopy and biopsies for Helicobacter pylori culture. The number of H. pylori isolated increased with age reaching a peak at 51 to 60 years of age. Antral gastritis closely followed by duodenitis accounted for the highest number of H. pylori isolated, (87.5% and 85.7% respectively). In patients with duodenal ulceration only, 57% had H. pylori isolated from their antral biopsies, a result that was just slightly higher than that where no endoscopic diagnosis was made (50%).
N PROFLULEGODFREY. "Lule GN, Sang F, Ogutu EO.Helicobacter pylori in peptic ulcer disease in Kenya.East Afr Med J. 1991 May;68(5):324-7.". In: East Afr Med J. 1991 May;68(5):324-7. test; 1991. Abstract

Sixty six patients with dyspeptic symptoms underwent upper gastrointestinal endoscopy and biopsies for Helicobacter pylori culture. The number of H. pylori isolated increased with age reaching a peak at 51 to 60 years of age. Antral gastritis closely followed by duodenitis accounted for the highest number of H. pylori isolated, (87.5% and 85.7% respectively). In patients with duodenal ulceration only, 57% had H. pylori isolated from their antral biopsies, a result that was just slightly higher than that where no endoscopic diagnosis was made (50%).

N PROFLULEGODFREY. "Lule GN. Helicobacter pylori: an infectious agent in peptic ulcer disease? East Afr Med J. 1991 May;68(5):321-3. No abstract available.". In: East Afr Med J. 1991 May;68(5):321-3. test; 1991. Abstract

The range of clinical presentations of HIV-related disease in Africa has not been adequately described, despite the fact that many hospitals have to rely heavily on clinical diagnosis. Six hundred adult medical patients seen in the Casualty Department of the main Government hospital in Nairobi were enrolled in a study of the presentation and outcome of HIV-related disease: 506 of these patients were admitted, of whom 19 per cent (95) were HIV seropositive. The remaining 94 were dealt with as outpatients: 11 percent (10) of these were seropositive. A history of prior treatment for sexually transmitted disease and, if male, being uncircumcised, were associated with being seropositive. Three presentations were strongly associated with HIV infection: acute fever with no focus except the gastrointestinal tract (enteric fever-like illness), acute cough with fever (community-acquired pneumonia) and chronic diarrhoea with wasting. The WHO clinical case definition (CCD) for AIDS missed a substantial amount of HIV-related morbidity (sensitivity 39 per cent) and misidentified many seronegative patients (positive predictive value 59 per cent). In comparison with the Centers for Disease Control surveillance definition for AIDS, the CCD was specific (91 per cent) and sensitive (79 per cent) but only had a positive predictive values of 30 per cent: the CCD may therefore be a poor surveillance tool for AIDS. Seropositive patients were much more likely to die than were seronegative patients (39 per cent vs. 15 per cent mortality). Enteric fever-like illness was the presentation which most commonly proved fatal. A wider spectrum of disease is associated with underlying HIV immunosuppression than has previously been described in Africa.

OKOTH PROFOKOMBODUNCAN. "Luo Meets Latin: Linguistic Evidence for Contacts Between Speakers of Pre-Dholuo and Speakers of Lation.' In Proceeding of the Third Nilo-Saharan Linguistic Colloquim. Hamburg Buske Verlag.". In: A book review in Journal of African Languages and Linguistics Vol. 15 - 1, 80-85. CIGR Electocic Journal; 1991. Abstract
isolated from preterm neonates during the outbreak of gastroenteritis in hospital in Nairobi, Kenya, were resistance to trimethoprin-sulfathoxaxole, Chloramphenicol, oxytetracycline and ampicilin, but only a few strains were resistant to cefazolin, cefamandole, cefataximine, amikacin and nalidixic acid. Fourteen different antimicrobial resistance patterns were observed in the 229 strains of E.coli analyzed. Eighty-two percent of the EPEC strains belonged to two resistance patterns. There was no consistent relationship between palsmid profile group and antimicrobial resistance pattern, although one resistance pattern was more frequently observed in EAF-positive strins belonging to the dominant plasmid profile group. Nine percent of the EPEC strins were resistant to gentamicin compared to 37% in the non-EPEC group. No correlation was observed between administration of gentamicin and percentage of resistant strains isolated. None of the nine neonates receiving gentamicin died during the outbreak. Gentamicin resistance was observed in E.coli strains from six out of these nine neonates. Five out of fourteen neonates who received other antimicrobials, or no antibiotic at all, died. Key words: Enteropathogenic Escherichia Coli; antimicrobial resistance;
Mbithi PMF;, Mbiuki SM;, Nguhiu Mwangi JA;, Mogoa EG;, Kihurani DO. "Lameness in cattle in Kenya.".; 1990.
Mbithi PMF;, Mbiuki SM;, Nguhiu Mwangi JA;, Mogoa EG;, Kihurani DO. "Lameness in cattle in Kenya.".; 1990.
Mbithi PMF;, Mbiuki SM;, Nguhiu Mwangi JA;, Mogoa EG;, Kihurani DO. "Lameness in cattle in Kenya.".; 1990.
Mbithi PMF;, Mbiuki SM;, Nguhiu Mwangi JA;, Mogoa EG;, Kihurani DO. "Lameness in cattle in Kenya.".; 1990.
I.O JUMBA, S.O W. "Levels of aluminium in green leaf of clonala teas, black tea and black tea liquors and effects of rates of nitrogen fertilizers on the aluminium black tea contents.". In: Food Chemistry 35, 59-68. Association of Africa Universities; 1990. Abstract

Clonal teas have different aluminium content increasing with age of leaf. Although aluminium andfertilizernitrogen enhance teagrowth andteayields, respectively, field trials have shown no relationship between total aluminium content in the leaf and clonal tea yields. Higher aluminium concentrations were found in the dust grades of black tea than in the large size grades. However, aluminium levels decreased in the tea liquor from dust grades compared to the large size grades. Only up to 40% of the total aluminium in tea was infused into tea liquors; the amounts infused varied with clones and grading (sorting). Aluminium content of black tea was lowered by increasing rates of nitrogenous fertilizers, more frequent fertilizer application, and application of NPK 20:10:10 as opposed to NPKS 25:5:5:5.

AMOLO PROFACHOLAMILCAH. "Labour Metropolitan Capital and the Colonial State.". In: Transafrican Journal of History Vol. 19, 1990.; 1990. Abstract

Colonial policy makers argued that they were  bringing civilization and better standards of living to Africans.  One perceived problem they had to contend with  was the “ignorance” of their subject peoples.  In health delivery, in particular, colonial administrators believed that ignorance accounted for the poor levels of health among Africans, and that knowledge and that knowledge and other preventive measures would greatly enhance standards of living, for instance, among urban Africans. In this paper we test this philosophy against colonial urban health policy’s and show that racism in the delivery of services  greatly undermined African and Asian health in order to afford  high quality services for Europeans in Nairobi.

W DRKIRIMIMARGARET. "Land Use Patterns on Eastern and Southern Slopes of Mt. Kenya.". In: Published by University of Nairobi Press. ELOQUENT BOOKS NY, Strategic Book Group, Connecticut, USA. ISBN-978-1-60911-081-9.Pages1; 1990. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Macrophytes have been shown to perform important ecological roles in Lake Naivasha. Consequently, various studies regarding the impact of biotic factors on the macrophytes have been advanced but related studies on environmental parameters have lagged behind. In an attempt to address this gap, sampling on floating species and submergents was carried out in eight sampling sites in 2003 to investigate how they were influenced by a set of environmental factors. Soil texture (sandy sediments; P < 0.05, regression coefficient = - 0.749) and wind were the most important environmental parameters influencing the distribution and abundance of floating macrophytes. Combination of soil texture and lake-bed slope explained the most (86.3%) variation encountered in the submergents. Continuous translocation of the floating dominant water hyacinth to the western parts by wind has led to displacement of the submergents from those areas. In view of these findings, the maintenance and preservation of the steep Crescent Lake basin whose substratum is dominated by sand thus hosting most submergents remain important, if the whole functional purpose of the macrophytes is to be sustained.
A. DRSWAZURIMUHAMMED. ""Land Use Policy in Relation to Social Forestry in Kenya". Paper presented to the Social Forestry Refresher Course, Muguga, Nairobi, 12th to 16th March, 1990.". In: Key issues for Developing Countries. 1992 Ed., Bhatnagar S.C., pp. 103-114. Tata-Mcgraw-Hill. African International Business and Management Conference, Nairobi, Kenya; 1990. Abstract
This article reveals that the concept of education as a process of growth is a difficult one. Philosophers are, therefore, justified in being weary when pondering over its meaning, both in theory and practice. By way of conclusion, the article appreciates the complexities inherent in the growth theory of education, summarizing its major strength and weaknesses. Then it cautions educational planners and practitioners to be weary when, and if, they translate the theory into practice, so that they utilize the strengths inherent in the theory whilst paying attention to the dangers of its inherent weaknesses.
OLE PROFMALOIYGEOFFREYM. "LANGMAN, V.A., ROBERTS, T.J., BLACK, J., MALOIY, G.M.O., HEGLUND,N.C., WEBER, J.M. and TAYLOR, C.R.(1990) African elephants: energetics of walking in a large mammal.Physiologist 33, 36A.". In: Annual Conference Society for integrative and Comparative Biology New Orleans Louisiana U.S.A. EAMJ; 1990. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
L DRLEGGEPATRICK. "Legge, P.L. The significance of Aswa Lineament in South Sudan; 15th Colloquium on Geology of Africa in Nancy, France,.". In: Published in: recent Data in African Earth Sciences; CIFEC. Heinrich Boll Foundation.; 1990.
L DRLEGGEPATRICK. "Legge, P.L., Earthquakes and strike slip faults in South Sudan,.". In: 15th Colloquium on African Geology in Nancy; France. Heinrich Boll Foundation.; 1990.
"Life in the Balance: Ecological Sociology of Turkana Nomads, Nairobi." Nairobi: Acts Press, African Center for Technological Studies; 1990. Abstract
n/a
L. PROFWANJALACHRISTOPHER. ""Literature in our Time and the University", in Trends and Future of University in Kenya in the 1990s and Beyond. Edited by Wanjala-Kerre and Kenneth Gray.". In: [Nairobi Masaki Publishers].; 1990. Abstract

A random sample survey using personal interviews was conducted in Machakos and Makueni Districts of Kenya in 1992 to estimate the level of rabies vaccination of the dog population. To substantiate the results of the interviews, a sample of the surveyed dogs 3 months old and above were bled for serum rabies antibody determination using an inhibition enzyme immunoassay (INH EIA). Of the 266 surveyed 3 months old and above, only 29% (77/266) were reportedly vaccinated against rabies. Out of the 197 dog sera titrated for rabies antibody, only 29% (57/197) had detectable antibodies and only 16% (32/197) had antibody tires equal to or greater than the threshold considered protective of 0.5 I.U/ml. There was a strong positive association between a history of previous vaccination and the detection of rabies antibodies. Of 133 dogs with no history of previous vaccination, 20% (26/133) had detectable antibodies. With the rabies incidence in Machakos and Makueni Districts still unacceptably high, the level of vaccination estimated in this survey is clearly inadequate for rabies control and measures designed to increase it are discussed.

Kariuki CN. "Linear programming as applied to determination of human expenditure of food.". In: A paper presented in the 1st ORSEA Conference in Nairobi. African Crop Science Society; 1989. Abstract

Operations Research techniques involving modelling a situation or a problem and finding an optimal solution for it. These tools are not designed nor intended to replace managerial decision making, but rather their purpose is to aid in the decision-making process by providing a quantitative basis for decision making. Unfortunately, the proliferation of OR tools in organizational decision making has been lacking, with concerns been expressed about the limited awareness of the business community of OR's potential and capability. Current study was based in the premise that students provide an appropriate avenue, as agent of change, in sensitizing and demonstrating the potential and capacity of OR tools/techniques in resolving various problems, both in public and private sector. Study aimed at evaluating the use of OR as tools of data analysis at MBA level. A sample of 100 MBA research projects undertaken between 2005 and 2007 was randomly selected and their objectives and selected data analysis tools recorded. Where OR tools were not used, the research evaluated if there was a possibility of using OR tools. Results indicated low usage of OR as data analysis, though there was a high potential for the use of OR tools.

KAAYA GP. "Laboratory evaluation of biocontrol potentials of entomopathogenic fungi for tsetse.". In: Proceedings of the 7th Tanzania Veterinary Association Scientific Conference. Arusha, Tanzania; 1989.
Wamukowa N. "Leaning and Teaching in Professional Faculties af the University of Nairobi.". In: #6th Technical Communication Conference. Chicago; 1989.
Alexander RM;, Maloiy GMO. "Locomotion of African mammals."; 1989.
OLE PROFMALOIYGEOFFREYM. "LANGMAN, V.A. and MALOIY, G.M.O.(1989) Passive obligatory heterothermy of the giraffe. Journal of Physiology London 415, 89P.". In: Proceedings of International Union of Physiological Sciences 17, 335. EAMJ; 1989. Abstract
Serum acid phosphatase was measured in patients with enlarged benign and malignant prostate before and after rectal examination. Amongst the patients with benign glands, rectal examination did not produce any significant false elevation of the enzyme. Rectal examination, however, caused a rise in the enzyme level in a few untreated cancer patients and in cancer patients who has become refractory to hormonal therapy. This rise would help rather than mislead in the diagnosis of malignant prostate and also in the identifying treated patients who had become refractory to treatment. Thus, when serum acid phosphatase is properly determined, elevated levels should always arouse suspicion of malignant prostate or other lesions associated with high enzyme level even is such determination was preceded by rectal examination. There appears to be no merit in the teaching that the determination of serum acid phosphatase should be delayed after rectal examination.
OKOTH PROFOGENDOHASTINGW. ""Legal responses to grasslands management and desertification control in East Africa" In Wild Verway (ed.) Nature Management and Sustainable Development ICS, Amsterdam.". In: Cent. Afri. J. Pharm.Sci. 5(3): 60-66. Cent. Afri. J. Pharm.Sci. 5(3): 60-66; 1989. Abstract
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
CIARUNJI PROFCHESAINA. "'Little Fishes and Crocodiles' (A Short Story) in Little Amu and the Kobole ed. by W.Mwotia et al Oxford University Press:.". In: Macmillan Kenya. uon press; 1989. Abstract
coming soon at the webstie
N PROFLULEGODFREY. "Lule GN, Okoth F, Ogutu EO, Mwai SJ. HBV markers (HBsAg, HBSAb, HBCAb in 160 medical students at Kenyatta National Hospital. East Afr Med J. 1989 May;66(5):315-8.". In: East Afr Med J. 1989 May;66(5):315-8. test; 1989. Abstract

In an exercise to study the immunogenicity and reactogenicity of the Engerix B vaccine, 160 medical students were screened for Hepatitis B Markers (HBsAg, HBsAb and HBcAb) with a view to vaccinating those that were negative. 18% were HBsAg + ve, 33% were HBsAb + ve and 38% were positive for the HBcAb. These figures were extremely high and obviated the need to vaccinate the students as they begin their clinical years.

OTIENO PROFOGUTUELLY. "Lule GN, Okoth F, Ogutu EO, Mwai SJ.HBV markers (HBsAg, HBSAb, HBCAb in 160 medical students at Kenyatta National Hospital. East Afr Med J. 1989 May;66(5):315-8.". In: East Afr Med J. 1989 Jan;66(1):10-4. Journal of British Ceramic Transactions, 99 [5], 206-211.; 1989. Abstract
In an exercise to study the immunogenicity and reactogenicity of the Engerix B vaccine, 160 medical students were screened for Hepatitis B Markers (HBsAg, HBsAb and HBcAb) with a view to vaccinating those that were negative. 18% were HBsAg + ve, 33% were HBsAb + ve and 38% were positive for the HBcAb. These figures were extremely high and obviated the need to vaccinate the students as they begin their clinical years.
OUMA PROFPAMBAHANNINGTON. "Laga M., Plummer F.A., Piot P., Data P., Namara W. Ndinya-Achola J.O., Nsanze H., Maitha G., Ronald A.R., Pamba H.O. and Brunham R.: Prophylaxis of Gonococcal and Chlamydia Ophthalmia Neonatorum: Silver Nitrate Versus Tetracycline. New Eng. J. Med. 318: 6.". In: New Eng. J. Med. 318: 653, 1988. Opuscula Mathematica,; 1988. Abstractprophylaxis_of_gonococcal_and_chlamydial_ophthalmia_neonatorum.pdf

This paper investigates the possibilities of applying emerging management theories and techniques to constitutionally created offices in Kenya and East African region. The benefits from application of these theories, particularly in the judicial services are highlighted.

MWIGA PROFMWABUGERMANO. ""Labor Unions and the Distribution of Wages and Employment in South Africa," (with T. Paul Schultz), Industrial and Labor Relations Review, 51:4, pp. 681-703.". In: Proceedings Sixth College on Thin Film Technology, July 24th . University of Nairobi; 1988. Abstract
The role of pastoralist women in conflict resolution and management (study funded by SIDA though IMPACT)
IKIARA MRGERRISHONK. "Labour Productivity of Kenyan Workers.". In: paper prepared JASPA, Addis Ababa. Asian Economic and Social Society; 1988. Abstract
JASPA Working Paper, ILO, Addis Ababa
O. PROFNDINYA-ACHOLAJ. "Laga M. Plummer FA, Piot P, Datta P, Namaara W, Ndinya-Achola JO, Nsanze H, Maitha G, Ronald AR, Pamba HO, Brunham RC.Prophylaxis of gonococcal and chlamydial ophthalmia neonatorum: N. Engl. J. Med. 318 (II): 653 - 657, 1988.". In: N. Engl. J. Med. 318 (II): 653 - 657, 1988. IBIMA Publishing; 1988. Abstract
OBJECTIVE–To determine the efficacy of the nonoxynol 9 contraceptive sponge in preventing sexual acquisition of the human immunodeficiency virus (HIV). DESIGN–Prospective, randomized placebo-controlled trial. SETTING–Research clinic for prostitutes in Nairobi, Kenya. PATIENTS AND INTERVENTIONS–One hundred thirty-eight HIV-seronegative women were enrolled, of whom 74 were assigned to nonoxynol 9 sponge use and 64 to placebo use. These two groups did not significantly differ with respect to demographic characteristics, sexual practices, or prevalence of genital infections at enrollment, except for a lower number of sex partners per week and a higher initial prevalence of genital ulcers among women assigned to nonoxynol 9 sponge use. Among the 116 women who returned for follow-up, the mean durations of follow-up were 14 and 17 months for the two groups, respectively. MAIN OUTCOME MEASURE–HIV seroconversion. RESULTS–Nonoxynol 9 sponge use was associated with an increased frequency of genital ulcers (relative risk [RR], 3.3; P less than .0001) and vulvitis (RR, 3.3; P less than .0001) and a reduced risk of gonococcal cervicitis (RR, 0.4; P less than .0001). Twenty-seven (45%) of 60 women in the nonoxynol 9 sponge group and 20 (36%) of 56 women in the placebo group developed HIV antibodies. The hazard ratio for the association between nonoxynol 9 sponge use and HIV seroconversion was 1.7 (95% confidence interval [CI], 0.9 to 3.0). Using multivariate analysis to control for the presence of genital ulcers at enrollment, the adjusted hazard ratio for the association between nonoxynol 9 sponge use and seroconversion was 1.6 (95% CI, 0.8 to 2.8). CONCLUSIONS–Genital ulcers and vulvitis occurred with increased frequency in nonoxynol 9 sponge users. We were unable to demonstrate that nonoxynol 9 sponge use was effective in reducing the risk of HIV infection among highly exposed women.
OKOTH PROFOGENDOHASTINGW. ""Law and government in Kenya"; in Kenya 1963-1988: An Official Handbook, Ministry of Information and Broadcasting.". In: Cent. Afri. J. Pharm.Sci. 5(3): 60-66. Cent. Afri. J. Pharm.Sci. 5(3): 60-66; 1988. Abstract
The identification of five novel compounds, pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-erythromycin A-6,9-hemiketal, 8,9-anhydro-pseudo-N-demethylerythromycin A-6,9-hemiketal, 5-O-beta-D-desosaminylerythronolide A and 15-nor-erythromycin C, in mother liquor concentrates of Streptomyces erythraeus is described. The pseudo-erythromycin derivatives are characterized by a 12-membered macrocyclic ring as a result of C13––C11 trans-lactonization. The five compounds have very little antimicrobial activity.
P DRKITHINJIJACOB. "LC-GC, SFC-GC and SFC and SFE-GC interfacing.". In: Anal. Chem. 60 (1988) 683-702A. University of nairobi; 1988. Abstract
Abstract in Bellamy, M. and B. Greenshields (eds), Issues in Agricultural Development: Sustainability and Cooperation. IAAE Occasional Paper No. 6. Dartmouth Publishing Co. Ltd, Aldershot.
PROF. NTIBA MICHENIJ. "Lecture Notes on Coastal and Estuarine Studies Vol. 26: Coastal Ocean Studies off Natal, South Africa. E.H. Schumann (Ed.).". In: Springer - Verlag New York. 271 p. Reviewed for the Journal of Fish Biology. ELOQUENT BOOKS NY, Strategic Book Group, Connecticut, USA. ISBN-978-1-60911-081-9.Pages1; 1988. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Macrophytes have been shown to perform important ecological roles in Lake Naivasha. Consequently, various studies regarding the impact of biotic factors on the macrophytes have been advanced but related studies on environmental parameters have lagged behind. In an attempt to address this gap, sampling on floating species and submergents was carried out in eight sampling sites in 2003 to investigate how they were influenced by a set of environmental factors. Soil texture (sandy sediments; P < 0.05, regression coefficient = - 0.749) and wind were the most important environmental parameters influencing the distribution and abundance of floating macrophytes. Combination of soil texture and lake-bed slope explained the most (86.3%) variation encountered in the submergents. Continuous translocation of the floating dominant water hyacinth to the western parts by wind has led to displacement of the submergents from those areas. In view of these findings, the maintenance and preservation of the steep Crescent Lake basin whose substratum is dominated by sand thus hosting most submergents remain important, if the whole functional purpose of the macrophytes is to be sustained.
H DRWANJALASAMSON. "Lema VM, Ojwang SBO, Wanjala S. Rupture of the Gravid Uterus at the Kenyatta National Hospital: A five year review (1984-1988) (Submitted to East African Medical Journal).". In: East African Medical Journal. Academic Press Elsevier. Int.; 1988. Abstract

PIP: In 1990, the annual population growth rate in Kenya was 3.8%, among the highest rates world wide. The ever growing adolescent fertility rate (111-152/1000 from 1969-1989) contributed to this rapid growth. Further repeat pregnancies among adolescents remained high in the 1980's and ranged from 20%-28.6%, depending on the survey. Even though overall prevalence of pregnancy fell 15.4% between 1978-1984, it remained the same for the 15-19 year old group. Teenage births have made up at least 35% of total deliveries. 1985 data revealed that even though adolescents represent 11-35% of the total obstetric population, problems ranked high among them: 38% of all eclampsia cases and high maternal mortality (102/100,000 vs. 57/100,000 older mothers). Studies showed that adolescents are sexually active, are ignorant about contraception, and do not use contraception. Yet contraceptive and family planning services are free in Kenya. Nevertheless the teenagers are at high risk of an unwanted pregnancy, sexually transmitted diseases (STDs), and AIDS. In the early 1980s, Kenyatta National Hospital reported 53% of 74.1% of septic abortion cases being single women were between 14-20 years old. Similar results emerged from other studies. Health professionals believed these results to be underestimated, however. In the 1980s, 33% of all adolescents between 13-15 years old in a rural area had gonorrhea. In Kenyatta, 36% of pregnant 15-24 year olds had at least 1 STD while,e only 16% of those 24 years old did. Further, teenagers are especially vulnerable to psychological problems when they 1st learn of their pregnancy. Health services should be geared to meet the specific needs of adolescents, such as contraception education and antenatal services. PMID: 12316815 [PubMed - indexed for MEDLINE]

HENRY PROFINDANGASI. ""Literature and the Teaching of English." In The Place of Grammar in the Teaching of English. Published proceedings of an International Conference held at the British Council.". In: (Published in Japanese). GIGA German Institute of Global and Area Studies, Hamburg, July 2009; 1988. Abstract
This integrative review on the teaching of reading in Kenyan primary schools provides a foundation for the growing movement there to improve reading education. In gathering sources for this review, we took an inclusive historical stance. Thus, we did not dismiss research reports that lacked traditional indicators of quality such as being published in peer-reviewed journals. We used multiple methods to find relevant research and associated documents, including two trips to Kenya. The review is organized by six topics: (a) language of instruction, (b) reading instruction, (c) reading materials, (d) reading culture, (e) assessment, and (f) teacher development. The review concludes with six proposals for policymakers, educational researchers, and teacher educators for the development of reading instruction based on what we learned in reviewing the literature. The first proposals are intended specifically to address the teaching of reading in Kenya, but they may be relevant to other sub-Saharan nations. The final proposal encourages others to conduct similar reviews to make possible a handbook of reading in Africa.
OMONDI MRMISANGOQUIRENEBERNARD. "Locally Made Woodworking Machine. A Technical Report, 1985 (Revised 1988).". In: Far East J. of Theo. Stat. 18 (2), pp. 161 . Far East Journal of Theoretical Statistics; 1988. Abstract
v:* {behavior:url(#default#VML);} o:* {behavior:url(#default#VML);} w:* {behavior:url(#default#VML);} .shape {behavior:url(#default#VML);} 12.00 Normal 0 false false false EN-GB X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} Common nearly best linear estimates of location and scale parameters of normal and logistic distributions, which are based on complete samples, are considered. Here the population from which the samples are drawn is either normal or logistic population or a fusion of both distributions and the estimates are computed when it is not yet known which of the two populations (between the normal and logistic) is true. The problem discussed in this paper involves two possible population types in a given sample. Samples of sizes  and  are used to validate these estimates and a comparison of their variances is made with those of the best linear unbiased estimators (BLUEs) for normal and logistic distributions.
N DRWAMBUGUMILCAH. "Lule GN, Ogutu EO, Okoth F, Were JB, Wambugu M. Sclerotherapy in the treatment of bleeding oesophageal varices: preliminary report. East Afr Med J. 1988 Jun;65(6):416-20. Review.". In: East Afr Med J. 1988 Jun;65(6):416-20. Review. University of Nairobi.; 1988. Abstract
A prospective study was carried out at Kenyatta National Hospital (KNH) between June 1987 and September 1988 to look at some aspects of obstructive jaundice in patients above 12 years of age. Screening for cases was done by use of abdominal ultrasonography. A total of 20 cases (11 females, 9 males) were diagnosed. Carcinoma of the head of pancreas accounted for 55% of cases of the obstruction, followed by gallstones (10%), hepatocellular carcinoma (10%) and gall bladder tumour (10%).
N PROFLULEGODFREY. "Lule GN, Ogutu EO, Okoth F, Were JB, Wambugu M. Sclerotherapy in the treatment of bleeding oesophageal varices: preliminary report. East Afr Med J. 1988 Jun;65(6):416-20. Review. No abstract available.". In: East Afr Med J. 1988 Jun;65(6):416-20. test; 1988. Abstract

A case of cryptococcal hepatitis is described in a patient with Human Immunodeficiency Virus (HIV) infection. There has been no previous reports of this in the East African literature. A review of world literature showed that the entity of cryptococcal hepatitis is very rare.

OTIENO PROFOGUTUELLY. "Lule GN, Ogutu EO, Okoth F, Were JB, Wambugu M.Sclerotherapy in the treatment of bleeding oesophageal varices: preliminary report. East Afr Med J. 1988 Jun;65(6):416-20. Review. No abstract available.". In: East Afr Med J. 1989 Dec;66(12):830-3. Journal of British Ceramic Transactions, 99 [5], 206-211.; 1988. Abstract
The mean fasting insulin level in 30 apparently normal Kenyan Africans was determined by Radio-Immuno Assay (RIA) technique based on coat A-count. The mean value was found as 16.33 microIu/ml with a standard deviation (s.d) of 10.51 microIu/ml. The mean at 95% confidence interval (CI) for the population studied was 16.33 +/- 1.92. The findings are similar to what have been reported among the caucasians. This paper also reports on a case of insulinoma in a young female patient at Kenyatta National Hospital (KNH).
P. PROFSITUMAFRANCISD. "Legal Framework for Conservation,ownership,Access and Utilization of African Biodiversity:Medical plant and Food Crops,A paper presented at the OAU scientific Technical and Research Commission/Kenya Industrial Property Office/Development partners workshop.". In: Law Journal,Issue No.4.; 1987. Abstract

New Directions in water legislation in Kenya?. A Paper presented as the National Workshop on environmental Governance in kenya, held at the UNEP Headquarters Gigiri, Nairobi, March 29-30. 2000

L DRLEGGEPATRICK. "Legge, P.L. & B. Meissner, (1987): Fracture systems and mineralization in East Equatoria Province, South Sudan, Special volume by IGCP Project 247;.". In: Arusha Conference 1987; published in Dar Es. Heinrich Boll Foundation.; 1987.
P. PROFSITUMAFRANCISD. "Legislative Protectction of the Working Environment in kenya with Special Reference to Industry, an unpublished thesis submitted to the univesity of nairobi in partial fulfillment of the requirement fo the degree of Master of Law (Ll.m).". In: Law Journal,Issue No.4.; 1987. Abstract

New Directions in water legislation in Kenya?. A Paper presented as the National Workshop on environmental Governance in kenya, held at the UNEP Headquarters Gigiri, Nairobi, March 29-30. 2000

JOHN MRNDOLOISAAC. "Lewis, J. and I.J. Ndolo, (1987): Estimating Moisture Availability for Rice in Mwea, Kenya.". In: Agric. Jour. Vol. 41: (81-90). Association of Africa Universities; 1987. Abstract
Vertex epidural haematomas (VEDH) are rare and difficulties are encountered in diagnosis and management. This is a case report of a patient with a vertex epidural haematoma who presented with signs of severe head injury with upper limb decerebrate posture. We discuss the challenges of radiological investigation and neurosurgical management of VEDH.
SHEM MRON&#39;GONDO. "LL.M Thesis, 1987, Towards Sustainable Development: Environmental Degradating and the rural Poor of Kenya.". In: International Journal of BiochemiPhysics Vol. 6 & 7, (Nos. 1 & 2) : 45 . Jane A. Otadoh,, Sheila A. Okoth, James Ochanda, James P. Khaindi; 1987. Abstract
Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} Hepatocellular carcinoma results when cancerous cells are localized in the liver. It is distributed globally with high prevalence in sub-Saharan African, southern Asia, China and Japan. Diagnosis is experimental and in many cases inaccurate due to unreliability of markers. Prognosis is poor and the cost of treatment prohibitive. Conventional radiation and chemotherapy lead to loss of hair, fertility and general weakening of the body`s immune system increasing a patient`s risk to infection. These observations underscore the need for improved, or additional methods of cancer diagnosis and management. We investigated the effect of polysaccharide rich Pleurotus pulmonarius fruit body extracts on progression of chemically induced hepatocellular carcinoma in CBA mice. Addition of Pleurotus pulmonarius extracts in diet delayed progression of carcinogenesis suggesting   that these extracts may be useful as   adjuvants to conventional cancer therapies.   Key words: carcinogenesis; mice; mushroom extracts; pleurotus pulmunarius   Corresponding author: Ms Carolyne Wasonga, Department of Biochemistry, University of Nairobi, P.O. Box 30197, Nairobi,  Kenya. E-mail: carox27@yahoo.ca     Charles O.A. Omwandho, Susanne E. Gruessner, John Falconer, Hans-R Tinneberg, Timothy K. Roberts. IS OVINE PLACENTAL IGG TOXIC TO HUMAN PERIPHERAL BLOOD NATURAL KILLER CELLS?
JAMES PROFODEK. "LL.M Thesis, 1987, Towards Sustainable Development: Environmental Degradating and the rural Poor of Kenya.". In: Paper presented at the WIPO High Level Forum on IP Policy and Strategy, Tokyo . Prof. James Otieno-Odek; 1987. Abstract
J. O. Midiwo, A. Yenesew, B. F. Juma, S. Dereses, J. A. Ayoo, A. Aluoch and S. Guchu There are several described medicinal plants in Kenya from a flora of approximately 10,000 members. Strong cross-medical information from the 42 ethnic groups points to the high potential of some of these species. The Myrsinaceae are well established ethno-anthelmintics and anti-bacterials. They are harbingers of long alkyl side chain benzoquinones which clearly have a protective function from their histochemical disposition. The main benzoquinone in the sub-family Myrsinodae is embelin while for the Maesodae it is maesaquinone together with its 5-acetyl derivative; the distribution of these benzoquinones by their alkyl side chain length or the presence/absence of a 6-methyl group is in accord with morphological sub-family de-limitation. The benzoquinones showed anti-feedant, anti-microbial, phytotoxic, acaricidal, insecticidal and nematicidal activity. Many other benzoquinones of medium and minor concentration were also isolated and characterised. Some plants belonging to the Polygonaceae which are widely used as ethno-anthelmintics have been studied. The common anthelmintic anthraquinones were obtained from all five Rumex species while the naphthalenic acetogenin derivative, nepodin was more selectively distributed. The leaf of Polygonum senegalense is up to 17% surface exudate; about thirteen non polar flavonoid derivatives (chalcones, dihydrochalcones, flavanones and a flavone) have been isolated from it. From the internal aerial tissues of this plant, the major flavonoids were common flavonoids, quercetin, kaempferol, luteolin and their glycosides. The only unique compound isolated from this plant was 2prime-glucosyl-6prime-hydroxy-4prime-methoxydihydrochalcone whose aglycone, uvangolatin is part of the exudate mixture. Other leaf exudate plants studied include the stomach-ache medicine, Psiadia punctulata (Compositae) from which novel methylated flavonoids, kaurene and trachyloban diterpenes have been found
N PROFOGOLAELIJAHS. "LORE W, OGOLA E.N; Medico social Characteristics of Cardiac patients in Obstetrical Unit Of Kenyatta National Hospital. A preliminary report of an on-going prospective study. J.Obs. Gynaecol. East and Central Africa 6:83,1987.". In: J.Obs. Gynaecol. East and Central Africa 6:83,1987. Kisipan, M.L.; 1987. Abstract
The study aimed at evaluating tolerability and efficacy of the combination enalapril 20 mg with hydrochlorothiazide 12.5 mg (co-renitec) as first line therapy in black patients with mild to moderate primary hypertension. Fifty patients completed a twelve weeks of open clinical study preceded by two weeks of washout period. They were evaluated every four weeks and haematological, biochemical urine microscopy and electrocardiographic tests were undertaken before the start and after the completion of study. Pre-treatment values of mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 172.16 mm hg (+/- 20.41) and 104.38 mm hg (+/- 7.339) respectively. The usual daily dosage was one tablet which was increased to two after eight weeks in case the DBP was not normalized, i.e. less than or equal to 95 mm hg. In 44 (88%) patients, the DBP was normalised at the end of the study period; three patients (6%) were resistant to treatment and another three (6%) exhibited labile response to the treatment. Clinical tolerance was considered to be very good with only five episodes of headache, backache and anxiety, probably not related to the test drug. Biological tolerance was excellent: there was no change in the haematologic parameters; there was a decrease of 5% in mean blood urea, of 9% in the mean serum creatinine and of 4% in the mean serum uric acid and a 5% increase in plasma potassium from 3.99 to 4.28 mmol/l.(ABSTRACT TRUNCATED AT 250 WORDS)
N PROFLULEGODFREY. "Lule GN, Wankya BM, Shah MV, Greenfield C. Peptic ulcer disease at Kenyatta National Hospital: an endoscopic experience. East Afr Med J. 1987 Oct;64(10):638-42. No abstract available.". In: East Afr Med J. 1987 Oct;64(10):638-42. test; 1987. Abstract

A case of cryptococcal hepatitis is described in a patient with Human Immunodeficiency Virus (HIV) infection. There has been no previous reports of this in the East African literature. A review of world literature showed that the entity of cryptococcal hepatitis is very rare.

M. PROFLUTIFELIX. "Luti, F.M. (1987). Experimental modelling of axial temperature profiles of buoyant diffusion flames. African Journal of Science and Technology, Series A, vol. 6, no. 1, 76-80.". In: East Afr Med J. 1999 May;76(5):281-3. UN-HABITAT; 1987. Abstract
Mean temperatures were measured along the axis of propane gas flames using a porous ceramic burner. Data for fire heat release rates ranging form 13.3kW to 30.6kW were taken and analyzed. It was found that the lower zone of a fire in a clam environment could be conveniently divided into three regions. For the same heat release rates, the fires were subjected to a cross flow of 0.72ms-1 and it was found that along the axis, the three zones could be identified. The excess temperature in the intermittent zone decreased with height to the power of 0.60 for the calm environment and 1.11 with crossflow. In the plume zone, excess temperature decreased with 1.87 power for the clam case and 2.05 with crossflow case, all data when plotted on log plots fell on a single curve.
M. PROFLUTIFELIX. "Luti, F.M. (1987). Experimental modelling of axial temperature profiles of buoyant diffusion flames. African Journal of Science and Technology, Series A, vol. 6, no. 1, 76-80.". In: East Afr Med J. 1999 May;76(5):281-3. UN-HABITAT; 1987. Abstract
Mean temperatures were measured along the axis of propane gas flames using a porous ceramic burner. Data for fire heat release rates ranging form 13.3kW to 30.6kW were taken and analyzed. It was found that the lower zone of a fire in a clam environment could be conveniently divided into three regions. For the same heat release rates, the fires were subjected to a cross flow of 0.72ms-1 and it was found that along the axis, the three zones could be identified. The excess temperature in the intermittent zone decreased with height to the power of 0.60 for the calm environment and 1.11 with crossflow. In the plume zone, excess temperature decreased with 1.87 power for the clam case and 2.05 with crossflow case, all data when plotted on log plots fell on a single curve.
MOHAMED PROFABDULAZIZ. "Language choice and Information Flow.". In: Waigani Seminar. University of Papua New Guinea; 1986.
Gachuiri CK;, Carles AB;, Schwartz HJ. "Levels, causes and factors affecting mortality in a herd of small East African goats on a semi-arid thornbush Savannah."; 1986. Abstract

Kenya comprises vast arid and semi-arid areas and at the present level of technology and economic infrastructure in the country, the only feasible way to prod-:&z food for human consumption from these areas is through domestic ruminants. Small stock production has played a major role in th economy of range areas in the past 10 years. Sheep and goats have contributed significantly more than cattle in terms of livestock products in these areas (Semenye, 1977). The goat population has recently been estimated at 7.7 million with 40% of these being kept by pastoralists (Stotz, 1983). An increasing proportion of goats is observed in the pastoralists flocks with increasing aridity of the environment, leading to the assumption that goats are better adapted to the conditions of the arid rangeland of Northern Kenya. High mortality rates, especially prcweaning, has been cited as a major constraint on improving productivity. Wilson et al. (1985) reported a preweaning mortality of 28.6% for goats in a Maasai ranch. Carles et al. (1982), working in a pastoral area in Northern Kenya, reported mortalities of 6-12% for breeding females, rising as high as 66% during the first year of life. An opportunity arose to study in more detail, the causes, levels and factors affecting mortality in a typical pastoral system with the establishment, by the Department of Animal Production in cooperation with the Ministry of Livestock Development, the European Economic Community, the German Research Foundation and the German Agency for Technical cooperation, of a research station in a pastoral area near Isiolo.

OKEYO DRMWAIALFAYO. "L.C. Iniguez, G.E. Bradford and Okeyo A. Mwai. 1986. Lambing Date and Lambing Production of Spring-mated Rambouillet, Dorset and Finn sheep Ewes and their F1 Crosses. .". In: Journal of Animal Science. 63: 715-728. Rao, W. O., Ogonji, J. A.. and Aywa, S.; 1986. Abstract
PIP: This research report studies several biochemical and histochemical aspects of cervical carcinoma and explores their use in follow-up of patients undergoing radiotherapy. Material came from 19 patients with invasive cervical carcinoma admitted to Kenyatta National Hospital. A control group consisted of 20 women matched for age who attended clinics at the hospital but were not suffering from any malignant disease; control tissue for histological examination was obtained from 3 women who had undergone hysterectomy for uterine fibroids. Biochemical assays for alkaline and acid phosphatases in patients with cervical carcinoma show an increase in alkaline phosphatase in carcinomatous tissue (35.7 umoles/hr/mg) as opposed to normal tissue (7.2). Acid phosphatase values were only moderately raised. Assays of the same enzymes in blood showed a less marked difference between patients and controls (ranges of 7.5-20.8 and 3-14, respectively). When examined histochemically, increased alkaline phosphatase activity was observed in connective tissue, epithelium of the glands and blood capillaries of tumor tissue. 1 section containing normal tissue bordering carcinomatous tissue demonstrated normal alkaline phosphatase activity in the normal tissue and increased activity in the tumor tissue. In summary, there is increased enzyme activity around the tumor areas, but values for serum levels show an overlap of normal and abnormal cases and are therefore not predictive. Results demonstrate a clear difference in activities of these enzymes in carcinomatous tissue and normal tissue, which may be of value in follow-up care.
O. PROFNDINYA-ACHOLAJ. "Laga M, Namaara W, Brunham RC, Brunham RC, D'Costa LJ, Nsanze H, Piot P, Kummoto D, Ndinya-Achola JO, Slaney L, Ronald AR, Plummer FA. Single dose therapy of gonococcal ophthalmia with ceftriaxone. N. Engl. J. Med. 315: 1382 - 85, 1986.". In: N. Engl. J. Med. 315: 1382 - 85, 1986. IBIMA Publishing; 1986. Abstract
OBJECTIVE–To determine the efficacy of the nonoxynol 9 contraceptive sponge in preventing sexual acquisition of the human immunodeficiency virus (HIV). DESIGN–Prospective, randomized placebo-controlled trial. SETTING–Research clinic for prostitutes in Nairobi, Kenya. PATIENTS AND INTERVENTIONS–One hundred thirty-eight HIV-seronegative women were enrolled, of whom 74 were assigned to nonoxynol 9 sponge use and 64 to placebo use. These two groups did not significantly differ with respect to demographic characteristics, sexual practices, or prevalence of genital infections at enrollment, except for a lower number of sex partners per week and a higher initial prevalence of genital ulcers among women assigned to nonoxynol 9 sponge use. Among the 116 women who returned for follow-up, the mean durations of follow-up were 14 and 17 months for the two groups, respectively. MAIN OUTCOME MEASURE–HIV seroconversion. RESULTS–Nonoxynol 9 sponge use was associated with an increased frequency of genital ulcers (relative risk [RR], 3.3; P less than .0001) and vulvitis (RR, 3.3; P less than .0001) and a reduced risk of gonococcal cervicitis (RR, 0.4; P less than .0001). Twenty-seven (45%) of 60 women in the nonoxynol 9 sponge group and 20 (36%) of 56 women in the placebo group developed HIV antibodies. The hazard ratio for the association between nonoxynol 9 sponge use and HIV seroconversion was 1.7 (95% confidence interval [CI], 0.9 to 3.0). Using multivariate analysis to control for the presence of genital ulcers at enrollment, the adjusted hazard ratio for the association between nonoxynol 9 sponge use and seroconversion was 1.6 (95% CI, 0.8 to 2.8). CONCLUSIONS–Genital ulcers and vulvitis occurred with increased frequency in nonoxynol 9 sponge users. We were unable to demonstrate that nonoxynol 9 sponge use was effective in reducing the risk of HIV infection among highly exposed women.
O. PROFNDINYA-ACHOLAJ. "Laga M, Plummer FA, Nsanze H, Namaara W, Brunham RC, Ndinya-Achola JO, Maitha G, Ronald AR, D'Costa LJ, Bhullar V, Mati JY, Fransen L, Cheang M, Piot P.Epidemiology of ophthalmia neonatorum in Kenya. Lancet ii: 1145 - 1149, 1986.". In: Lancet ii: 1145 - 1149, 1986. IBIMA Publishing; 1986. Abstract
OBJECTIVE–To determine the efficacy of the nonoxynol 9 contraceptive sponge in preventing sexual acquisition of the human immunodeficiency virus (HIV). DESIGN–Prospective, randomized placebo-controlled trial. SETTING–Research clinic for prostitutes in Nairobi, Kenya. PATIENTS AND INTERVENTIONS–One hundred thirty-eight HIV-seronegative women were enrolled, of whom 74 were assigned to nonoxynol 9 sponge use and 64 to placebo use. These two groups did not significantly differ with respect to demographic characteristics, sexual practices, or prevalence of genital infections at enrollment, except for a lower number of sex partners per week and a higher initial prevalence of genital ulcers among women assigned to nonoxynol 9 sponge use. Among the 116 women who returned for follow-up, the mean durations of follow-up were 14 and 17 months for the two groups, respectively. MAIN OUTCOME MEASURE–HIV seroconversion. RESULTS–Nonoxynol 9 sponge use was associated with an increased frequency of genital ulcers (relative risk [RR], 3.3; P less than .0001) and vulvitis (RR, 3.3; P less than .0001) and a reduced risk of gonococcal cervicitis (RR, 0.4; P less than .0001). Twenty-seven (45%) of 60 women in the nonoxynol 9 sponge group and 20 (36%) of 56 women in the placebo group developed HIV antibodies. The hazard ratio for the association between nonoxynol 9 sponge use and HIV seroconversion was 1.7 (95% confidence interval [CI], 0.9 to 3.0). Using multivariate analysis to control for the presence of genital ulcers at enrollment, the adjusted hazard ratio for the association between nonoxynol 9 sponge use and seroconversion was 1.6 (95% CI, 0.8 to 2.8). CONCLUSIONS–Genital ulcers and vulvitis occurred with increased frequency in nonoxynol 9 sponge users. We were unable to demonstrate that nonoxynol 9 sponge use was effective in reducing the risk of HIV infection among highly exposed women.
K PROFGACHENECHARLESK. "The land quality: .". In: Biological Agricultural & Horticultural Journal, Vol 19(1), 49-62. F.N. kamau, G. N Thothi and I.O Kibwage; 1986. Abstract
A model for the establishment of a four-dimensional regional geodetic reference datum is presented. Starting from the three-dimensional integrated geodetic network model, formulations for the establishment of a four-dimensional regional datum are developed. Astronomic latitudes, astronomic longitudes, gravity values, gravity potential differences, gravity differences, and GPS-vectors are considered as observables. The estimated parameters defining the datura are point coordinates, deflections of the vertical and geoidai undulations, and velocities and accelerations on the positional coordinates. The network datum is considered observed over several epochs with parameters estimated from previous epochs being introduced into later epochs as stochastic prior information parameters.
L DRLEGGEPATRICK. "Legge, P.L.: Geological Map, Juba Sheet 1:250 000; Geology and Land Use. .". In: Published by the Polytechnic of Berlin, Berlin. Heinrich Boll Foundation.; 1986.
OMONDI MRMISANGOQUIRENEBERNARD. "Locally Made Laundry Machine. A technical Report, 1986.". In: Far East J. of Theo. Stat. 18 (2), pp. 161 . Far East Journal of Theoretical Statistics; 1986. Abstract
v:* {behavior:url(#default#VML);} o:* {behavior:url(#default#VML);} w:* {behavior:url(#default#VML);} .shape {behavior:url(#default#VML);} 12.00 Normal 0 false false false EN-GB X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} Common nearly best linear estimates of location and scale parameters of normal and logistic distributions, which are based on complete samples, are considered. Here the population from which the samples are drawn is either normal or logistic population or a fusion of both distributions and the estimates are computed when it is not yet known which of the two populations (between the normal and logistic) is true. The problem discussed in this paper involves two possible population types in a given sample. Samples of sizes  and  are used to validate these estimates and a comparison of their variances is made with those of the best linear unbiased estimators (BLUEs) for normal and logistic distributions.
N PROFMUSOKERACHEL. "Low birthweight. East Afr Med J . 1986 Feb; 63 ( 2 ): 89-90 . No abstract available. PMID: 3720609 [PubMed - indexed for MEDLINE] Musoke RN.". In: East Afr Med J . 1986 Feb; 63 ( 2 ): 89-90 . Far East Journal of Theoretical Statistics; 1986. Abstract
No abstract available.
O. PROFNDINYA-ACHOLAJ. "Lubwama SW, Nsanze H, Plummer F, Ndinya-Achola J, Ronald AR, D'Costa LJ, Naamara W, Maitha G.Laboratory diagnosis of chancroid in Nairobi, Kenya. East Afr Med J. 1986 Jun;63(6):389-94.". In: East Afr Med J. 1986 Jun;63(6):389-94. IBIMA Publishing; 1986. Abstract
Routine procedures used to isolate Haemophilus ducreyi in a busy laboratory are reported. Identification was based on colony morphology and nutritional and biochemical properties of 120 fresh isolates of H. ducreyi. These isolates grew very well on Gonococcal Agar and Mueller-Hinton Agar incubated at 34 degrees C in candle extinction jars containing moistened filter paper. Colonies varied in size, giving a polymorphic appearance. They were smooth, dome-shaped, and buff-yellow to grey in colour, and measured 2 mm in diameter. They could be pushed intact across the agar surface. By microscopic examination of gram-stained smears the isolates were gram-negative coccobacilli arranged in short chains, clumps or whorls and occasionally in typical "rail track" arrangements. Individual bacteria showed bipolar staining. Colonies autoagglutinated in saline. All strains were catalase-negative and did not produce indole or H2S. They were oxidase- and beta-lactamase positive and required X but not V factor for growth. Now that reliable techniques have been developed and characteristics established it is possible for most clinical laboratories to isolate and identify this organism from most patients with chancroid.
O. PROFNDINYA-ACHOLAJ. "Lubwama SW, Plummer F, Ndinya-Achola JO, Nsanze H, Namaara W, D'Costa LJ. Isolation and identification of H. ducreyi in a clinical laboratory. J. Med. Microbiol. 22: 175 - 178, 1986.". In: J. Med. Microbiol. 22: 175 - 178, 1986. IBIMA Publishing; 1986. Abstract
OBJECTIVE–To determine the efficacy of the nonoxynol 9 contraceptive sponge in preventing sexual acquisition of the human immunodeficiency virus (HIV). DESIGN–Prospective, randomized placebo-controlled trial. SETTING–Research clinic for prostitutes in Nairobi, Kenya. PATIENTS AND INTERVENTIONS–One hundred thirty-eight HIV-seronegative women were enrolled, of whom 74 were assigned to nonoxynol 9 sponge use and 64 to placebo use. These two groups did not significantly differ with respect to demographic characteristics, sexual practices, or prevalence of genital infections at enrollment, except for a lower number of sex partners per week and a higher initial prevalence of genital ulcers among women assigned to nonoxynol 9 sponge use. Among the 116 women who returned for follow-up, the mean durations of follow-up were 14 and 17 months for the two groups, respectively. MAIN OUTCOME MEASURE–HIV seroconversion. RESULTS–Nonoxynol 9 sponge use was associated with an increased frequency of genital ulcers (relative risk [RR], 3.3; P less than .0001) and vulvitis (RR, 3.3; P less than .0001) and a reduced risk of gonococcal cervicitis (RR, 0.4; P less than .0001). Twenty-seven (45%) of 60 women in the nonoxynol 9 sponge group and 20 (36%) of 56 women in the placebo group developed HIV antibodies. The hazard ratio for the association between nonoxynol 9 sponge use and HIV seroconversion was 1.7 (95% confidence interval [CI], 0.9 to 3.0). Using multivariate analysis to control for the presence of genital ulcers at enrollment, the adjusted hazard ratio for the association between nonoxynol 9 sponge use and seroconversion was 1.6 (95% CI, 0.8 to 2.8). CONCLUSIONS–Genital ulcers and vulvitis occurred with increased frequency in nonoxynol 9 sponge users. We were unable to demonstrate that nonoxynol 9 sponge use was effective in reducing the risk of HIV infection among highly exposed women.
O. PROFNDINYA-ACHOLAJ. "Lubwama SW, Plummer FA, Ndinya-Achola J, Nsanze H, Namaara W, D'Costa LJ, Ronald AR.Isolation and identification of Haemophilus ducreyi in a clinical laboratory.J Med Microbiol. 1986 Sep;22(2):175-8.". In: J Med Microbiol. 1986 Sep;22(2):175-8. IBIMA Publishing; 1986. Abstract
Routine procedures used to isolate Haemophilus ducreyi in a busy laboratory are reported. Identification was based on colony morphology and nutritional and biochemical properties of 120 fresh isolates of H. ducreyi. These isolates grew very well on Gonococcal Agar and Mueller-Hinton Agar incubated at 34 degrees C in candle extinction jars containing moistened filter paper. Colonies varied in size, giving a polymorphic appearance. They were smooth, dome-shaped, and buff-yellow to grey in colour, and measured 2 mm in diameter. They could be pushed intact across the agar surface. By microscopic examination of gram-stained smears the isolates were gram-negative coccobacilli arranged in short chains, clumps or whorls and occasionally in typical "rail track" arrangements. Individual bacteria showed bipolar staining. Colonies autoagglutinated in saline. All strains were catalase-negative and did not produce indole or H2S. They were oxidase- and beta-lactamase positive and required X but not V factor for growth. Now that reliable techniques have been developed and characteristics established it is possible for most clinical laboratories to isolate and identify this organism from most patients with chancroid.
"Language and Politics in the Horn of Africa.". In: International Symposium on the Horn of Africa. University of Cairo, Cairo; 1985.
G. PROFSIMIYUVINCENT. "Les Classes Sociales en Afrique de Iquest Pre-Coloniale in He-CHI Revue dEtudes Francaises de Iuniversite de Nairobi.". In: P. 47-53 Editorship: African in Time Perspective. Weekly Radio Talks on African History, V.O.K. Kireti VM, Atinga JEO; 1985. Abstract

The human body louse, Pediculus humanus, showed eighteen midgut proteins ranging between 12 and 117 kDa, when analysed by SDS-PAGE electrophoresis. Seven of them (12 kDa, 17 kDa, 29 kDa, 35 kDa, 40 kDa, 55 kDa and 97 kDa) were major bands based on their intensity of staining. The immunization of rabbits with a midgut extract elicited the production of protective polyclonal antibodies. These antibodies reacted strongly with all major midgut proteins as well as with 63 kDa and 117 kDa proteins when tested by the Western blot technique. The analysis of the proteins revealed that the 12 kDa, 25 kDa, 29 kDa, 35 kDa, 45 kDa, 87 kDa and 97 kDa proteins are glycosylated and none of them contained a lipid moiety. By electroelution, the proteins of 35 kDa and 63 kDa were purified. On trypsinization, the proteins of 35 kDa and 63 kDa produced four major fragments (F1, F2, F3, and F4) when resolved on a 18% SDS-PAGE. The F1 fragment of the 35 kDa protein reacted with the polyclonal antibodies by the immunoblot technique.

Waithaka K. "Liatris forcing in Kenya."; 1985.
L. PROFWANJALACHRISTOPHER. "La Litteratura Dopo L'Independenza, in Synchron Numero 5 - Anno 4 Decembre 1985, 53-65.". In: published by Agip Ptroli of Milan Italy.; 1985. Abstract

A random sample survey using personal interviews was conducted in Machakos and Makueni Districts of Kenya in 1992 to estimate the level of rabies vaccination of the dog population. To substantiate the results of the interviews, a sample of the surveyed dogs 3 months old and above were bled for serum rabies antibody determination using an inhibition enzyme immunoassay (INH EIA). Of the 266 surveyed 3 months old and above, only 29% (77/266) were reportedly vaccinated against rabies. Out of the 197 dog sera titrated for rabies antibody, only 29% (57/197) had detectable antibodies and only 16% (32/197) had antibody tires equal to or greater than the threshold considered protective of 0.5 I.U/ml. There was a strong positive association between a history of previous vaccination and the detection of rabies antibodies. Of 133 dogs with no history of previous vaccination, 20% (26/133) had detectable antibodies. With the rabies incidence in Machakos and Makueni Districts still unacceptably high, the level of vaccination estimated in this survey is clearly inadequate for rabies control and measures designed to increase it are discussed.

P. PROFMUREITHILEOPOLD. "Labour Utilization and the Employment Problem in Africa in P. Ndegwa L>P. Mureithi and R.H Green Development Options for Africa in the 1980 and Beyond Nairobi Oxford University Press.". In: Gabbay R. &Siddique A., ed., Good Governance Issues and Sustainable Development: The Indian Ocean Region (New Delhi: Vedams Books). ISCTRC; 1985. Abstract
Differentiation of bloodstream-form trypanosomes into procyclic (midgut) forms is an important first step in the establishment of an infection within the tsetse fly. This complex process is mediated by a wide variety of factors, including those associated with the vector itself, the trypanosomes and the bloodmeal. As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification and characterization of a midgut lectin-trypsin complex from the tsetse fly, Glossina longipennis. Parasitol. Res. 81, 276-281]. The protein (lectin-trypsin complex) was found to be capable of stimulating differentiation of bloodstream trypanosomes in vitro. Using polyclonal antibodies to the complex, we screened a G. fuscipes fuscipes cDNA midgut expression library and identified a putative proteolytic lectin gene. The cDNA encodes a putative mature polypeptide with 274 amino acids (designated Glossina proteolytic lectin, Gpl). The deduced amino acid sequence includes a hydrophobic signal peptide and a highly conserved N-terminal sequence motif. The typical features of serine protease trypsin family of proteins found in the sequence include the His/Asp/Ser active site triad with the conserved residues surrounding it, three pairs of cysteine residues for disulfide bridges and an aspartate residue at the specificity pocket. Expression of the gene in a bacterial expression system yielded a protein (M(r) approximately 32,500). The recombinant protein (Gpl) bound d(+) glucosamine and agglutinated bloodstream-form trypanosomes and rabbit red blood cells. In addition, the protein was found to be capable of inducing transformation of bloodstream-form trypanosomes into procyclic forms in vitro. Antibodies raised against the recombinant protein showed cross-reactivity with the alpha subunit of the lectin-trypsin complex. These results support our earlier hypothesis that this molecule is involved in the establishment of trypanosome infections in tsetse flies.
A. PROFKARANIFLORIDA. ""Leadership in Community Projects".". In: Pan- African Institute, Project Management Workshop, Kabwe, Zambia. 1984 and 1985. Journal of BiochemiPhysics; 1985. Abstract
   

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