Classical instructional methods have been used and will continue to be used in the teaching and learning process. However, their limitations in different circumstances vary depending on student and instructor needs, where they are and who they are. In this paper we consider issues and implications o f ICT-supported learning with regard to pedagogy in the teaching and learning process. We will consider the context of developing ICT methodologies and strategies which can be integrated into the teaching and learning process within schools and higher learning institutions. The paper first presents a background and a justification for the underlying work. Approaches that can be applied to integrating ICTs effectively in the teaching and learning process are then discussed. Intelligent teaching and learning methods are then considered and issues on how to ameliorate the impediments are discussed within the schools’ and higher learning institutions’ set-ups respectively. The paper ends by making some recommendations and a conclusion at the end.