Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection.

Citation:
E.N. PN. "Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection.". 1995.

Abstract:

J Infect Dis. 1995 Mar;171(3):686-9.
Rapid progression to disease in African sex workers with human immunodeficiency virus type 1 infection.
Anzala OA, Nagelkerke NJ, Bwayo JJ, Holton D, Moses S, Ngugi EN, Ndinya-Achola JO, Plummer FA.
Source
Department of Medical Microbiology, University of Nairobi, Kenya.
Erratum in
 J Infect Dis 1996 Jun;173(6):1529.
Abstract
From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-1-related disease. The effect of several covariables on disease progression was studied using a Weibull proportional hazards model. The Weibull survival model was fitted to the observed incubation times. Estimates of the median duration to CDC stage IV-A and IV-C disease were 3.5 and 4.4 years, respectively. Condom use before seroconversion was associated with a reduced risk of CDC stage IV-A disease (relative risk = .64, P < .05). The incubation time of HIV-1-related disease is extremely short in this population.
Comment in
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Destroy user interface controlRapid progression to human immunodeficiency virus type 1 disease. [J Infect Dis. 1996]
PMID:
7876618
[PubMed - indexed for MEDLINE]

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