Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants.

Citation:
Pankau MD, Dalton Wamalwa, Benki-Nugent S, Tapia K, Ngugi E, Langat A, Otieno V, Moraa H, Maleche-Obimbo E, Overbaugh J, John-Stewart GC, Lehman DA. "Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants." Open Forum Infect Dis. 2018;5(1):ofx268.

Abstract:

We compared change in HIV reservoir DNA following continued antiretroviral therapy (ART) vs short treatment interruption (TI) in early ART-treated Kenyan infants. While HIV DNA in the reservoir decayed with continued ART, HIV DNA levels were similar to pre-TI HIV DNA reservoir levels in most children after short TI.

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