Publications


2006

M, DRNJOROGEERNEST.  2006.  Japhet Magambo, Ernest Njoroge, Eberhard Zeyhle (2006) Epidemiology and Control of Echinococcosis in Sub-Saharan Africa.. Parasitology International, 55: S193 . : African Wildlife Foundation. Nairobi Abstract
Biodiversity offers multiple opportunities for development and improving human well-being. It is the basis for essential environmental services upon which life on Earth depends. Thus, its conservation and sustainable use are of critical importance. The opportunities and challenges associated with biodiversity typically apply over large geographical extents, although one or two issues may be more important at any given location. To avoid repetition, particular issues are highlighted in the sub-regional sections, not because they are restricted to those areas, but because they are best illustrated there. Deforestation is discussed under Central Africa, while relations between protected areas and adjacent populations are dealt with under Eastern Africa. Riparian biodiversity is discussed in Northern Africa, climate change and invasive alien species (IAS) in Southern Africa, desertification in Western Africa, and endemism in the Western Indian Ocean (WIO) islands. Habitat degradation and resource overexploitation are discussed in this regional synthesis, because they are overwhelmingly important as drivers of biodiversity loss throughout Africa.
M, DRNJOROGEERNEST.  2006.  I. Buishi, E. Njoroge, E. Zeyhle, M. T. Rogan and P. S. Craig (2006) Canine echinococcosis in Turkana (north. United Nations Environment Programme. ISBN: 92-807-2691-9.. : African Wildlife Foundation. Nairobi Abstract
Biodiversity offers multiple opportunities for development and improving human well-being. It is the basis for essential environmental services upon which life on Earth depends. Thus, its conservation and sustainable use are of critical importance. The opportunities and challenges associated with biodiversity typically apply over large geographical extents, although one or two issues may be more important at any given location. To avoid repetition, particular issues are highlighted in the sub-regional sections, not because they are restricted to those areas, but because they are best illustrated there. Deforestation is discussed under Central Africa, while relations between protected areas and adjacent populations are dealt with under Eastern Africa. Riparian biodiversity is discussed in Northern Africa, climate change and invasive alien species (IAS) in Southern Africa, desertification in Western Africa, and endemism in the Western Indian Ocean (WIO) islands. Habitat degradation and resource overexploitation are discussed in this regional synthesis, because they are overwhelmingly important as drivers of biodiversity loss throughout Africa.

2005

M, DRNJOROGEERNEST.  2005.  I.E. Buishi, E.M. Njoroge, O. Bouamra, P.S. Craig (2005) Canine echinococcosis in northwest Libya: assessment of coproantigen ELISA, and a survey of infection with analysis of risk factors.. Veterinary Parasitology 130: 223 . : African Wildlife Foundation. Nairobi Abstract
{ In order to determine the prevalence and risk factors for canine echinococcosis in different endemic localities in the Tripoli area of northwest Libya, stray dogs were examined post-mortem, and owned dogs screened for Echinococcus granulosus infection using a standardised genus specific coproantigen ELISA. The prevalence of E. granulosus infection at necropsy in stray-dogs was 25.8% (15/58, 95% CI 15.3-39.0%), and 21.6% (72/334, 95% CI 17.3-26.4%) of owned dogs tested were positive by coproantigen ELISA. Sheepdogs appeared to have a significantly higher copro-positive prevalence (19/19 positive
M, DRNJOROGEERNEST.  2005.  P.M.F. Mbithi, E.M. Njoroge, J.M. Gathuma, T. M. Wachira, J. K. Magambo, S. Njiru, and E. Zeyhle (2005) Evaluation of Ethyl Alcohol in Treatment of Cystic Echinococcosis Using Puncture, Aspiration, Introduction, Reaspiration (PAIR) Technique.. Journal of Animal and Veterinary Advances 4 (3): 414-416. : African Wildlife Foundation. Nairobi Abstract
This study was carried out to evaluate the effect of 95% ethyl alcohol in PAIR technique. Animals naturally infected with Echinococcus were randomly divided into two groups. In the test group, cysts (n=7) were punctured, drained and injected with 95% ethyl alcohol, while in the control group, cysts (n=9) were only punctured and drained. The procedure was done under ultrasound guidance. Ultrasound showed collapsed endocysts after cyst puncture in both groups. One month later, there was decrease in cyst size, increased echogenicity and complete or partial detachment of the endocyst. Postmortem examination of the cysts in test group showed gross degeneration with marked fibrosis of the surrounding liver tissue. Incision of the cysts revealed turbid yellow cystic contents and degenerated endocysts. Microscopically, only debris and dead protoscoleces with detached hooks were seen. In the control group, the cysts appeared grossly intact but flaccid. Incision of the cysts showed clear fluid with intact endocysts. However, microscopic examination of the cyst fluid showed that the protoscoleces were dead with detached hooks. In the test group, histopathology showed host cell reaction consist of infiltrated, adventitial layer with neutrophils, eosinophils and plasma cells. In addition, the liver tissue was destroyed and replaced with young fibroblasts and mesenchymal cells. In the control group, histopathology showed detachment of the laminate layer of the cyst from the adventitia, and inflammatory cells in both the adventitia and the liver tissues. However, the degree of inflammation was markedly less in the control than in the test group. The findings suggest that puncture alone may be sufficient to kill the protoscoleces, possibly due to the detachment of the endocyst from the host wall.
M, DRNJOROGEERNEST.  2005.  Ernest Njoroge, Peter Mbithi, Timothy Wachira, Joseph Gathuma, Peter Gathura, T E Maitho, Japhet Magambo, Eberhard Zeyhle (2005) Comparative Study of Albendazole and Oxfendazole in the Treatment of Cystic Echinococcosis in Sheep and Goats.. International Journal of Applied Research in Veterinary Medicine, 3 (2): 97 . : African Wildlife Foundation. Nairobi Abstract
Biodiversity offers multiple opportunities for development and improving human well-being. It is the basis for essential environmental services upon which life on Earth depends. Thus, its conservation and sustainable use are of critical importance. The opportunities and challenges associated with biodiversity typically apply over large geographical extents, although one or two issues may be more important at any given location. To avoid repetition, particular issues are highlighted in the sub-regional sections, not because they are restricted to those areas, but because they are best illustrated there. Deforestation is discussed under Central Africa, while relations between protected areas and adjacent populations are dealt with under Eastern Africa. Riparian biodiversity is discussed in Northern Africa, climate change and invasive alien species (IAS) in Southern Africa, desertification in Western Africa, and endemism in the Western Indian Ocean (WIO) islands. Habitat degradation and resource overexploitation are discussed in this regional synthesis, because they are overwhelmingly important as drivers of biodiversity loss throughout Africa.

2004

M, DRNJOROGEERNEST.  2004.  Mbae, C. K., Githigia, S. M., Njoroge, E. M., Magambo, J. K., Otieno, R. O (2004). The prevalence of gastrointestinal nematodes in small ruminants in semi-arid Turkana District of Kenya.. Bulletin of Animal Health and Production in Africa, 2004 (Vol. 52) (No. 2) 85-90. : African Wildlife Foundation. Nairobi Abstract
A study was undertaken in the semiarid northern Turkana district of Kenya to estimate the prevalence of gastrointestinal nematodes in small ruminants. The study involved 1106 sheep and goats of various ages. The study was conducted between January and August 2001 and covered both the dry and wet seasons. All the animals were shedding nematode eggs throughout the study period. Faecal shedding was higher in young animals compared to adults and the infection was heavier in sheep. The faecal egg counts were significantly higher during the wet season for both sheep and goats. Haemonchus contortus was the main nematode encountered in coprocultures (goats 73%, sheep 62.8%) and postmortem total worm counts. Other nematodes encountered included Trichostrongylus axei, Trichostrongylus colubriformis, Bunostomum trigonocephalum, Oesophagostomum columbianum and Trichuris ovis. This is the first report of B. trigonocephalum in small ruminants in the semiarid areas of Kenya. In conclusion, gastrointestinal helminths may be a potential constraint to the health and production of small ruminants in the Turkana district. H. contortus is the main nematode species affecting the small ruminants in this area.
M, DRNJOROGEERNEST.  2004.  Ankel Dinkel, Ernest M. Njoroge, Anja Zimmermann, Marcus Walz, Eberhard Zeyhle, Ibrahim E. Elmahdi, Ute Mackenstedt, Thomas Romig (2004) A PCR system for the detection of species and the genotypes of the Echinococcus granulosus complex, with reference to . International Journal for Parasitology 34: 645 . : African Wildlife Foundation. Nairobi Abstract
This study was carried out to evaluate the effect of 95% ethyl alcohol in PAIR technique. Animals naturally infected with Echinococcus were randomly divided into two groups. In the test group, cysts (n=7) were punctured, drained and injected with 95% ethyl alcohol, while in the control group, cysts (n=9) were only punctured and drained. The procedure was done under ultrasound guidance. Ultrasound showed collapsed endocysts after cyst puncture in both groups. One month later, there was decrease in cyst size, increased echogenicity and complete or partial detachment of the endocyst. Postmortem examination of the cysts in test group showed gross degeneration with marked fibrosis of the surrounding liver tissue. Incision of the cysts revealed turbid yellow cystic contents and degenerated endocysts. Microscopically, only debris and dead protoscoleces with detached hooks were seen. In the control group, the cysts appeared grossly intact but flaccid. Incision of the cysts showed clear fluid with intact endocysts. However, microscopic examination of the cyst fluid showed that the protoscoleces were dead with detached hooks. In the test group, histopathology showed host cell reaction consist of infiltrated, adventitial layer with neutrophils, eosinophils and plasma cells. In addition, the liver tissue was destroyed and replaced with young fibroblasts and mesenchymal cells. In the control group, histopathology showed detachment of the laminate layer of the cyst from the adventitia, and inflammatory cells in both the adventitia and the liver tissues. However, the degree of inflammation was markedly less in the control than in the test group. The findings suggest that puncture alone may be sufficient to kill the protoscoleces, possibly due to the detachment of the endocyst from the host wall.
M, DRNJOROGEERNEST.  2004.  Ernest M. Njoroge & Eberhard Zeyhle (2004) (Eds) International Archives of the Hydatidosis Volume XXXV.. XXIst International Congress of Hydatidosis, August 2004.. : African Wildlife Foundation. Nairobi Abstract
This study was carried out to evaluate the effect of 95% ethyl alcohol in PAIR technique. Animals naturally infected with Echinococcus were randomly divided into two groups. In the test group, cysts (n=7) were punctured, drained and injected with 95% ethyl alcohol, while in the control group, cysts (n=9) were only punctured and drained. The procedure was done under ultrasound guidance. Ultrasound showed collapsed endocysts after cyst puncture in both groups. One month later, there was decrease in cyst size, increased echogenicity and complete or partial detachment of the endocyst. Postmortem examination of the cysts in test group showed gross degeneration with marked fibrosis of the surrounding liver tissue. Incision of the cysts revealed turbid yellow cystic contents and degenerated endocysts. Microscopically, only debris and dead protoscoleces with detached hooks were seen. In the control group, the cysts appeared grossly intact but flaccid. Incision of the cysts showed clear fluid with intact endocysts. However, microscopic examination of the cyst fluid showed that the protoscoleces were dead with detached hooks. In the test group, histopathology showed host cell reaction consist of infiltrated, adventitial layer with neutrophils, eosinophils and plasma cells. In addition, the liver tissue was destroyed and replaced with young fibroblasts and mesenchymal cells. In the control group, histopathology showed detachment of the laminate layer of the cyst from the adventitia, and inflammatory cells in both the adventitia and the liver tissues. However, the degree of inflammation was markedly less in the control than in the test group. The findings suggest that puncture alone may be sufficient to kill the protoscoleces, possibly due to the detachment of the endocyst from the host wall.
M, DRNJOROGEERNEST.  2004.  C.K. Mbae, S.M. Githigia, E.M. Njoroge, J.K. Magambo & R..Otieno (2004). The prevalence of gastrointestinal nematodes in small ruminants in Semi-Arid Turkana District of Kenya.. Bulletin of Animal Health and Production for Africa, 52: 85 . : African Wildlife Foundation. Nairobi Abstract
This study was carried out to evaluate the effect of 95% ethyl alcohol in PAIR technique. Animals naturally infected with Echinococcus were randomly divided into two groups. In the test group, cysts (n=7) were punctured, drained and injected with 95% ethyl alcohol, while in the control group, cysts (n=9) were only punctured and drained. The procedure was done under ultrasound guidance. Ultrasound showed collapsed endocysts after cyst puncture in both groups. One month later, there was decrease in cyst size, increased echogenicity and complete or partial detachment of the endocyst. Postmortem examination of the cysts in test group showed gross degeneration with marked fibrosis of the surrounding liver tissue. Incision of the cysts revealed turbid yellow cystic contents and degenerated endocysts. Microscopically, only debris and dead protoscoleces with detached hooks were seen. In the control group, the cysts appeared grossly intact but flaccid. Incision of the cysts showed clear fluid with intact endocysts. However, microscopic examination of the cyst fluid showed that the protoscoleces were dead with detached hooks. In the test group, histopathology showed host cell reaction consist of infiltrated, adventitial layer with neutrophils, eosinophils and plasma cells. In addition, the liver tissue was destroyed and replaced with young fibroblasts and mesenchymal cells. In the control group, histopathology showed detachment of the laminate layer of the cyst from the adventitia, and inflammatory cells in both the adventitia and the liver tissues. However, the degree of inflammation was markedly less in the control than in the test group. The findings suggest that puncture alone may be sufficient to kill the protoscoleces, possibly due to the detachment of the endocyst from the host wall.

2002

M, DRNJOROGEERNEST.  2002.  Njoroge EM, Mbithi PM, Gathuma JM, Wachira TM, Gathura PB, Magambo JK, Zeyhle E.(2002). A study of cystic echinococcosis in slaughter animals in three selected areas of northern Turkana, Kenya. Vet Parasitol. 2002 Feb 27;104(1):85-91.. : African Wildlife Foundation. Nairobi Abstract
In an attempt to establish the prevalence of cystic echinococcosis, a study was conducted in slaughter animals in three divisions of northern Turkana, Kenya. A total of 5752 goats, 588 sheep, 381 cattle and 70 camels were examined at slaughter. Echinococcus granulosus metacestodes were found in 19.4% of the cattle, 3.6% of sheep, 4.5% of goats and 61.4% of camels. The prevalence of cystic echinococcosis in cattle, sheep and goats was higher in Lokichogio than in either Kakuma or Central divisions. On the other hand, the prevalence of the disease in camels was higher in Central (84.6%) than either Lokichogio (70.6%) or Kakuma (50%). The differences in prevalence rates in different study areas are attributed to differences in environmental conditions, livestock stocking intensity and cross-border migration of livestock
M, DRNJOROGEERNEST.  2002.  E. M. Njoroge, P.M.F. Mbithi, J.M. Gathuma, T.M. Wachira, P.B. Gathura, J.K. Magambo, E. Zeyhle (2002) A study of cystic echinococcosis in slaughter animals in three selected areas of Northern Turkana, Kenya.. Veterinary Parasitology 104:85-91. : African Wildlife Foundation. Nairobi Abstract
A study was undertaken in the semiarid northern Turkana district of Kenya to estimate the prevalence of gastrointestinal nematodes in small ruminants. The study involved 1106 sheep and goats of various ages. The study was conducted between January and August 2001 and covered both the dry and wet seasons. All the animals were shedding nematode eggs throughout the study period. Faecal shedding was higher in young animals compared to adults and the infection was heavier in sheep. The faecal egg counts were significantly higher during the wet season for both sheep and goats. Haemonchus contortus was the main nematode encountered in coprocultures (goats 73%, sheep 62.8%) and postmortem total worm counts. Other nematodes encountered included Trichostrongylus axei, Trichostrongylus colubriformis, Bunostomum trigonocephalum, Oesophagostomum columbianum and Trichuris ovis. This is the first report of B. trigonocephalum in small ruminants in the semiarid areas of Kenya. In conclusion, gastrointestinal helminths may be a potential constraint to the health and production of small ruminants in the Turkana district. H. contortus is the main nematode species affecting the small ruminants in this area.

2001

M, DRNJOROGEERNEST.  2001.  Njoroge E.M. (2001) Evaluation of Ultrasonographic Diagnosis, Treatment Methods and Epidemiology of Cystic Echinococcosis in Sheep and Goats.. PhD Thesis, University of Nairobi. : African Wildlife Foundation. Nairobi Abstract
In an attempt to establish the prevalence of cystic echinococcosis, a study was conducted in slaughter animals in three divisions of northern Turkana, Kenya. A total of 5752 goats, 588 sheep, 381 cattle and 70 camels were examined at slaughter. Echinococcus granulosus metacestodes were found in 19.4% of the cattle, 3.6% of sheep, 4.5% of goats and 61.4% of camels. The prevalence of cystic echinococcosis in cattle, sheep and goats was higher in Lokichogio than in either Kakuma or Central divisions. On the other hand, the prevalence of the disease in camels was higher in Central (84.6%) than either Lokichogio (70.6%) or Kakuma (50%). The differences in prevalence rates in different study areas are attributed to differences in environmental conditions, livestock stocking intensity and cross-border migration of livestock

2000

M, DRNJOROGEERNEST.  2000.  Wabacha, J.K., Maribei J.M., Thaiya A.G., Munyua S.J.M., Karanja D.N., and Njoroge E.M. (2000) Progressive Atrophic Rhinitis in a Medium-scale pig farm in Kiambu, Kenya.. Journal of South African Veterinary Association 71(2): 122 - 124. : African Wildlife Foundation. Nairobi Abstract
Forty-two pigs in a herd of 117 displayed various clinical signs of progressive atrophic rhinitis. The main signs included sneezing, coughing, lachrymation, serous to mucopurulent nasal discharge, and nasal bleeding in 1 pig. Three pigs had lateral deviation of the snout, while 4 had brachygnathia superior with obvious deformation of the face. Four acutely affected weaner pigs appeared weak, while the 7 chronically-affected pigs appeared smaller than their apparently unaffected penmates of the same age. Treatment of the acutely affected pigs with long-acting oxytetracycline at 20 mg/kg body weight intramuscularly, repeated once after 7 days, reduced the severity but did not clear the sneezing from all the pigs. Fifteen pigs were slaughtered 2 months after the clinical diagnosis was made. The carcasses of the chronically affected pigs were about 15% lighter than those of the apparently normal pigs of the same age and from the same pen, which translated to a loss of 921.00 Kenya shillings per pig (US$13.7). Diagnosis of progressive atrophic rhinitis was confirmed by sectioning the snouts of randomly selected slaughtered pigs with obvious deformation of the snout. Sections were made at the level of the 1st/2nd upper premolar tooth. Varying degrees of turbinate atrophy, from mild to complete, were noted. Histopathology of the turbinates revealed metaplasia of nasal epithelium and fibrosis in the lamina propria.
M, DRNJOROGEERNEST.  2000.  Njoroge E.M., Mbithi P.M.F., Gathuma J.M., Wachira T.M., Magambo J.K. and Zeyhle E. E. (2000) Application of Ultrasonography in Prevalence Studies of Hydatid Cysts in Goats in Northwestern Turkana, Kenya and Toposaland Southern Sudan.. Onderstepoort Journal of Veterinary Research 67: 251-255. : African Wildlife Foundation. Nairobi Abstract
A study was done to determine the prevalence of hydatid cysts in goats using ultrasonography. A total of 1,390 goats were examined, 43,6 % (606/1,390) of them from north-western Turkana, Kenya, and 56,4% (784/1,390) from Toposaland, southern Sudan. Hydatid cysts were visualized in 1,82 % (11/ 606) of the goats from north-western Turkana and 4,34% (34/784) of those from Toposaland. Unlike abattoir surveys, the prevalence data obtained in this study were unbiased because entire flocks were examined. The lower prevalence rate of the disease in goats from Turkana was attributed to the hydatid disease control programme in that area, which is absent in Toposaland.
M, DRNJOROGEERNEST.  2000.  Njoroge E.M., Chema S., Gathuma J.M. (2000) A Study on the Deployment of Kenyan Veterinarians who Qualified Between 1988 and 1993.. The Kenya Veterinarian 19: 7 . : African Wildlife Foundation. Nairobi Abstract
A study was done to determine the prevalence of hydatid cysts in goats using ultrasonography. A total of 1,390 goats were examined, 43,6 % (606/1,390) of them from north-western Turkana, Kenya, and 56,4% (784/1,390) from Toposaland, southern Sudan. Hydatid cysts were visualized in 1,82 % (11/ 606) of the goats from north-western Turkana and 4,34% (34/784) of those from Toposaland. Unlike abattoir surveys, the prevalence data obtained in this study were unbiased because entire flocks were examined. The lower prevalence rate of the disease in goats from Turkana was attributed to the hydatid disease control programme in that area, which is absent in Toposaland.

1999

M, DRNJOROGEERNEST.  1999.  Njoroge E.M., Zeyhle E., Magambo J.K., Githaiga L.W., Muli R. (1999) Animal Diseases In a Pastoral Community - A Guide For Students and Other Paraveterinary Personnel.. Publishers: African Medical and Research Foundation (AMREF), Nairobi, KENYA.. : African Wildlife Foundation. Nairobi Abstract
Water intoxication is a condition that is common in cattle, and has also been reported in other domestic animals and man. A comprehensive description of the condition is lacking. For a better understanding of the condition, this paper reviews work that has been reported previously by various authors.
M, DRNJOROGEERNEST.  1999.  J.M.Maribei, J.K.Wabacha and E.M.Njoroge (1999) Streptococcal Meningitis in a five-month-old Male Lamb.. Journal of South African Veterinary Association 70(1) 2 . : African Wildlife Foundation. Nairobi Abstract
Water intoxication is a condition that is common in cattle, and has also been reported in other domestic animals and man. A comprehensive description of the condition is lacking. For a better understanding of the condition, this paper reviews work that has been reported previously by various authors.
M, DRNJOROGEERNEST.  1999.  Magambo J.K., Zeyhle E., Njoroge E.M., Githaiga L.W., Muli R. (1999) Hydatid Disease.. Publishers: African Medical and Research Foundation (AMREF), Nairobi, KENYA. : African Wildlife Foundation. Nairobi Abstract
Forty-two pigs in a herd of 117 displayed various clinical signs of progressive atrophic rhinitis. The main signs included sneezing, coughing, lachrymation, serous to mucopurulent nasal discharge, and nasal bleeding in 1 pig. Three pigs had lateral deviation of the snout, while 4 had brachygnathia superior with obvious deformation of the face. Four acutely affected weaner pigs appeared weak, while the 7 chronically-affected pigs appeared smaller than their apparently unaffected penmates of the same age. Treatment of the acutely affected pigs with long-acting oxytetracycline at 20 mg/kg body weight intramuscularly, repeated once after 7 days, reduced the severity but did not clear the sneezing from all the pigs. Fifteen pigs were slaughtered 2 months after the clinical diagnosis was made. The carcasses of the chronically affected pigs were about 15% lighter than those of the apparently normal pigs of the same age and from the same pen, which translated to a loss of 921.00 Kenya shillings per pig (US$13.7). Diagnosis of progressive atrophic rhinitis was confirmed by sectioning the snouts of randomly selected slaughtered pigs with obvious deformation of the snout. Sections were made at the level of the 1st/2nd upper premolar tooth. Varying degrees of turbinate atrophy, from mild to complete, were noted. Histopathology of the turbinates revealed metaplasia of nasal epithelium and fibrosis in the lamina propria.
M, DRNJOROGEERNEST.  1999.  E.M. Njoroge, J.M. Maribei, P.N. Mbugua and S.M. Njiru (1999) Water Intoxication in Cattle.. Journal of South African Veterinary Association 70(4): 177 . : African Wildlife Foundation. Nairobi Abstract
Water intoxication is a condition that is common in cattle, and has also been reported in other domestic animals and man. A comprehensive description of the condition is lacking. For a better understanding of the condition, this paper reviews work that has been reported previously by various authors.
M, DRNJOROGEERNEST.  1999.  E. Zeyhle, J.K. Magambo, J. Wachira, A. Gikandi and E.M. Njoroge (1999) Hepatic Hydatid Cyst in a Turkana Woman - Case Report.. African Journal of Health Sciences 6(1): 31 . : African Wildlife Foundation. Nairobi Abstract
Forty-two pigs in a herd of 117 displayed various clinical signs of progressive atrophic rhinitis. The main signs included sneezing, coughing, lachrymation, serous to mucopurulent nasal discharge, and nasal bleeding in 1 pig. Three pigs had lateral deviation of the snout, while 4 had brachygnathia superior with obvious deformation of the face. Four acutely affected weaner pigs appeared weak, while the 7 chronically-affected pigs appeared smaller than their apparently unaffected penmates of the same age. Treatment of the acutely affected pigs with long-acting oxytetracycline at 20 mg/kg body weight intramuscularly, repeated once after 7 days, reduced the severity but did not clear the sneezing from all the pigs. Fifteen pigs were slaughtered 2 months after the clinical diagnosis was made. The carcasses of the chronically affected pigs were about 15% lighter than those of the apparently normal pigs of the same age and from the same pen, which translated to a loss of 921.00 Kenya shillings per pig (US$13.7). Diagnosis of progressive atrophic rhinitis was confirmed by sectioning the snouts of randomly selected slaughtered pigs with obvious deformation of the snout. Sections were made at the level of the 1st/2nd upper premolar tooth. Varying degrees of turbinate atrophy, from mild to complete, were noted. Histopathology of the turbinates revealed metaplasia of nasal epithelium and fibrosis in the lamina propria.

1998

M, DRNJOROGEERNEST.  1998.  Maribei J.M., Njoroge E.M., and Njiro S. (1998) A Case of Ovine Lymphosarcoma in Kenya.. Journal of South African Veterinary Association 69(3): 105-107. : African Wildlife Foundation. Nairobi Abstract

Few chemotherapeutic agents are available for the medical management of hydatid disease caused by the parasite Echinococcus granulosus. In order to test the potential of oxfendazole for the treatment of infection with this parasite, nine infected goats and four sheep were given oxfendazole twice weekly at a dose of 30 mg/kg of body weight for 4 weeks and monitored by ultrasound for an additional 4 weeks. Efficacy was finally evaluated by postmortem examination, including determination of protoscolex viability and cyst wall histology. In treated animals, protoscolices were dead or absent in 97% of cysts from oxfendazole-treated animals compared to 28% of cysts from untreated control animals. On postmortem examination, 53% of cysts from treated animals were found to be grossly degenerate. A sample of those cysts that appeared potentially viable all demonstrated evidence of severe damage to the cyst wall. By light microscopy, cysts showed severe disorganization of the adventitial layer with invasion of inflammatory cells and in some cases frank necrosis with no apparent adventitial layer. The follow-up period for assessment of the drug's ability to cause complete degeneration and resorption of cysts was relatively short. This study, however, indicates that oxfendazole is at least as effective as and is easier to administer than albendazole for the treatment of hydatid disease.

M, DRNJOROGEERNEST.  1998.  Maribei J.M., Njoroge E.M., and Mbugua P.N. (1998) Clinical Manifestation of Experimental Water Intoxication in Calves.. Indian Journal of Animal Science 68(6): 531 . : African Wildlife Foundation. Nairobi Abstract

Few chemotherapeutic agents are available for the medical management of hydatid disease caused by the parasite Echinococcus granulosus. In order to test the potential of oxfendazole for the treatment of infection with this parasite, nine infected goats and four sheep were given oxfendazole twice weekly at a dose of 30 mg/kg of body weight for 4 weeks and monitored by ultrasound for an additional 4 weeks. Efficacy was finally evaluated by postmortem examination, including determination of protoscolex viability and cyst wall histology. In treated animals, protoscolices were dead or absent in 97% of cysts from oxfendazole-treated animals compared to 28% of cysts from untreated control animals. On postmortem examination, 53% of cysts from treated animals were found to be grossly degenerate. A sample of those cysts that appeared potentially viable all demonstrated evidence of severe damage to the cyst wall. By light microscopy, cysts showed severe disorganization of the adventitial layer with invasion of inflammatory cells and in some cases frank necrosis with no apparent adventitial layer. The follow-up period for assessment of the drug's ability to cause complete degeneration and resorption of cysts was relatively short. This study, however, indicates that oxfendazole is at least as effective as and is easier to administer than albendazole for the treatment of hydatid disease.

M, DRNJOROGEERNEST.  1998.  Maxson Sage A., Wachira T.M., Zeyhle E.E., Weber E., Njoroge E.M. and Smith G. (1998) Evaluation of Diagnostic Ultrasound as a Mass Screening Technique for Detection of Hydatid Cysts in the Liver and Right Lung of Sheep and Goats.. International Journal for Parasitology 28: 349 -353. : African Wildlife Foundation. Nairobi Abstract

Few chemotherapeutic agents are available for the medical management of hydatid disease caused by the parasite Echinococcus granulosus. In order to test the potential of oxfendazole for the treatment of infection with this parasite, nine infected goats and four sheep were given oxfendazole twice weekly at a dose of 30 mg/kg of body weight for 4 weeks and monitored by ultrasound for an additional 4 weeks. Efficacy was finally evaluated by postmortem examination, including determination of protoscolex viability and cyst wall histology. In treated animals, protoscolices were dead or absent in 97% of cysts from oxfendazole-treated animals compared to 28% of cysts from untreated control animals. On postmortem examination, 53% of cysts from treated animals were found to be grossly degenerate. A sample of those cysts that appeared potentially viable all demonstrated evidence of severe damage to the cyst wall. By light microscopy, cysts showed severe disorganization of the adventitial layer with invasion of inflammatory cells and in some cases frank necrosis with no apparent adventitial layer. The follow-up period for assessment of the drug's ability to cause complete degeneration and resorption of cysts was relatively short. This study, however, indicates that oxfendazole is at least as effective as and is easier to administer than albendazole for the treatment of hydatid disease.

M, DRNJOROGEERNEST.  1998.  Blanton R.E., Wachira T.M., Zeyhle E.E., Njoroge E.M., Magambo J.K. and Schantz P.M. (1998) Oxfendazole Treatment for Cystic Hydatid Disease in Naturally Infected Animals.. Antimicrobial Agents and Chemotherapy 42(3): 601 - 605. : African Wildlife Foundation. Nairobi Abstract

Few chemotherapeutic agents are available for the medical management of hydatid disease caused by the parasite Echinococcus granulosus. In order to test the potential of oxfendazole for the treatment of infection with this parasite, nine infected goats and four sheep were given oxfendazole twice weekly at a dose of 30 mg/kg of body weight for 4 weeks and monitored by ultrasound for an additional 4 weeks. Efficacy was finally evaluated by postmortem examination, including determination of protoscolex viability and cyst wall histology. In treated animals, protoscolices were dead or absent in 97% of cysts from oxfendazole-treated animals compared to 28% of cysts from untreated control animals. On postmortem examination, 53% of cysts from treated animals were found to be grossly degenerate. A sample of those cysts that appeared potentially viable all demonstrated evidence of severe damage to the cyst wall. By light microscopy, cysts showed severe disorganization of the adventitial layer with invasion of inflammatory cells and in some cases frank necrosis with no apparent adventitial layer. The follow-up period for assessment of the drug's ability to cause complete degeneration and resorption of cysts was relatively short. This study, however, indicates that oxfendazole is at least as effective as and is easier to administer than albendazole for the treatment of hydatid disease.

1997

M, DRNJOROGEERNEST.  1997.  Njoroge E.M., Maribei J.M. and Mbugua P.N. (1997) Pathological Changes of Calves Suffering from Experimental Water Intoxication.. Oderstepoort Journal of Veterinary Research 64(2): 110 . : African Wildlife Foundation. Nairobi Abstract
The pathology of calves that died from experimental water intoxication was investigated. Oedema of the brain and urinary bladder, and renal damage were significant pathological findings in these calves. The findings were attributed to positive water balance in calves suffering from water intoxication

1993

M, DRNJOROGEERNEST.  1993.  Njoroge E.M. (1993) A study of experimental water intoxication in calves.. MSc Thesis, University of Nairobi. : African Wildlife Foundation. Nairobi Abstract
The pathology of calves that died from experimental water intoxication was investigated. Oedema of the brain and urinary bladder, and renal damage were significant pathological findings in these calves. The findings were attributed to positive water balance in calves suffering from water intoxication

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