Gakuya, D.W., Mbaria, J.M., Mbithi,P.M.F. and Munenge, R.W. 2004. Evaluation of the bioactivity of some traditional medicinal plants using the Brine Shrimp Lethality Test. The Kenya Veterinarian 26: 8-11.

Citation:
WAWERU DRGAKUYADANIEL. "Gakuya, D.W., Mbaria, J.M., Mbithi,P.M.F. and Munenge, R.W. 2004. Evaluation of the bioactivity of some traditional medicinal plants using the Brine Shrimp Lethality Test. The Kenya Veterinarian 26: 8-11.". In: Journal of Etnopharmacology. Elsevier; 2004.

Abstract:

The purpose of this experiment was to evaluate the bioactivity of extracts of Chrysanthemum cineraraefolium Vis., Albizia anthelmintica A Brgn, Maerua edulis (Gilg) De wolf and Myrsine Africana L. Which are using tratitioanll as anthelmintic as using brine shrimp lethanitly test serial dilutions of 1000 ug/ml and 10 ug / ml of the extracts were put in five test tubes. Ten (10) brine shrimp larvae were immersed into each of the test tubes and the number surviving after 24 hours counted and the percentage mortality and LC for each extract was determined. Cl cinerariaefolium extract (pyrethrins) was active (LC 1000 ug/ml) of 18ug/ml. The methanol extacts of Maerua edulis, Maera subcordata and Myysine Africana were not active (LC 1000 ug/ml) the results indicated that C. cenerareafolium and A. Anthelmintica extracts have bioactivity and is the basis for their use as anthelmintic by pastoral communities. Brine shrimp lethality test was found to be a simple and rapid test and is thus recommended for similar studies.

Notes:

n/a

Website

UoN Websites Search