Dr. Diana Marangu MBChB, MMed (Paediatrics), MPH (Global Health)

Is a Lecturer in the Department of Paediatrics and Child Health. Her clinical and research interests include: Respiratory Health (TB, HIV, Wheeze, Obstructive Sleep Apnoea, Pulmonary Hypertension, Diagnostics, Vaccines) and Implementation Science.

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Marangu, D, Devine B, John-Stewart G.  2015.  Diagnostic accuracy of nucleic acid amplification tests in urine for pulmonary tuberculosis: a meta-analysis., 2015 Nov. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 19(11):1339-47. Abstract

To determine the diagnostic accuracy of tuberculosis (TB) nucleic acid amplification tests (NAATs) in urine samples for individuals with active pulmonary tuberculosis (PTB).

Marangu, D, Kovacs S, Walson J, Bonhoeffer J, Ortiz JR, John-Stewart G, Horne DJ.  2015.  Wheeze as an adverse event in pediatric vaccine and drug randomized controlled trials: A systematic review., 2015 Oct 5. Vaccine. 33(41):5333-41. Abstract

Wheeze is an important sign indicating a potentially severe adverse event in vaccine and drug trials, particularly in children. However, there are currently no consensus definitions of wheeze or associated respiratory compromise in randomized controlled trials (RCTs).


Marangu, D, Jowi C, Aswani J, Wambani S, Ruth Nduati.  2014.  Prevalence and associated factors of pulmonary hypertension in Kenyan children with adenoid or adenotonsillar hypertrophy., 2014 Aug. International journal of pediatric otorhinolaryngology. 78(8):1381-6. Abstract

Adenotonsillar hypertrophy is a common condition in childhood, whose serious complications of pulmonary hypertension and cor pulmonale are devastating but local prevalence is unknown. This study determined the prevalence and associated factors of pulmonary hypertension in children with adenoid or adenotonsillar hypertrophy at Kenyatta National Hospital, Kenya.

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