Nyindo M, Borus PK, Farah IO, Oguya FO, Makawiti DW.Schistosoma mansoni in the baboon: modulation of pathology after vaccination with polyclonal anti-idiotypic antibodies. Scand J Immunol. 1995 Dec;42(6):637-43.

Citation:
W. PROFMAKAWITIDOMINIC. "Nyindo M, Borus PK, Farah IO, Oguya FO, Makawiti DW.Schistosoma mansoni in the baboon: modulation of pathology after vaccination with polyclonal anti-idiotypic antibodies. Scand J Immunol. 1995 Dec;42(6):637-43.". In: Scand J Immunol. 1995 Dec;42(6):637-43. Groebner-Bases-Bibliography-RICAM; 1995.

Abstract:

Vaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated vaccine. Vaccination with the anti-idiotypic antibodies resulted in a significant reduction of pathology and granuloma size following challenge with live unattenuated cercariae. Results presented in this work are considered highly significant because the anti-idiotypic vaccine markedly influenced schistosomiasis morbidity which is the main consideration in this disease.

Notes:

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