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1979
Stelfox, John G; Kufwafwa JMSW; W. Distributions, densities and trends of elephants and rhinoceros in Kenya, 1977-1978 from KREMU's aerial surveys.; 1979. Abstract

Baseline information on densities, distributions and population trends of the African elephant was obtained during KREMU's 1977 and 1978 aerial surveys of all pastoral rangelands in Kenya. It was estimated in 1978 that there were between 44,000 and 67,000 elephants in Kenya 73% of the estimated 1977 population. The ratio of live to dead elephants in 1978 has further decreased to 44:56 compared to 51:49 in 1977. Of the 5,000 to 10,000 located in the general agricultural zone, most were in the national parks and forest reserves.

Skadhauge E;, Maloiy GMO. "The intestine and osmoregulation."; 1979.
Stelfox, John G; Kufwafwa JMSPDW; W; G. Livestock and wild herbivore populations in the Kenya rangelands in 1977 compared with 1978.; 1979. Abstract

Compares wild herbivore and livestock poulation data collected during the aerial suveys throughout the rangelands areas during 1977 and 1978. rangelands which were flown in straight line belt transects the first year at l0km spacing and the second at 5km apart. Elephant population estimates according to the ecoregions were: Northern Rift Valley 1,600 in 1977 but not included in 1978; Northern volcanics 1,600 in 1977 and 110 in 1978; Northern Central 4,170 in 1977 and 1,930 in 1978; North East 9,500 in 1977 and 3,060 in 1978; South Central 2,800 in 1977 and 4,130 in 1978, East Central-Coastal 13,900 in 1977 and 8,450 in 1978; South East 25,500 in 1977 and 21,900 in 1978; South West 1,800 in 1977 and 3,180 in 1978 providing a total estimate for 1977 of 59,800 and for 1978 of 42,800.

Maloiy GMO;, Macfarlane WV;, Shkolnik A. Mammalian herbivores.; 1979.Website
S PROFOLIECHJOSEPH. "Pyogenic thyroiditis at KNH. E.A. Med. J. VOl. 56 No. 1, 1979.". In: E.A. Med. J. VOl. 56 No. 1, 1979. PROF.J.S.OLIECH; 1979. Abstract

No abstract yet SUMMARY.

Although pyogenic thyroiditis is rare,the four cases have been seen and treated at Kenyatta National Hospital (KNH) over the last 10 years.This is a report of one of these cases detailing the clinical presentation and operative findings.
A middle aged female with a large painful shining anterior neck swelling of 4days duration.She had difficulty of swallowing,but no dyspnoea.She was febrile,with moderate anaemia, polymorph-leucocytosis (52%)and lymphocytosis(36%).Thyroid immunoglobulins were unavailable.131 iodine uptake studies was reduced,plain x-ray of the trachea/neck was unremarkable.
A thick suppurative pus from the left lobe grew on organisms.The discusses various forms of thyroid abcesses ,their causes and treatment.

Kasili EG, Wamola IA, Pamba HO, Shiramba T, Broekman JM. "Various pathological manifestations of leprosy: a multidisciplinary study.". 1979.
S PROFOLIECHJOSEPH. "Case report of pyogenic thyroiditis at Kenyatta National Hospital.". In: East Afr Med J. 1979 Jan;56(1):40-1. PROF.J.S.OLIECH; 1979. Abstract
No abstract available yet.
S. PROFEL-BUSAIDYABDULGAFURH. "The Development of the Solar Salt Industry in Kenya". A technical.". In: Kenya. J. Kenya Meteorological Soc; 1979. Abstract
   
1978
Brown PM, Tompkins CV, Juul S, Sönksen PH. "Mechanism of action of insulin in diabetic patients: a dose-related effect on glucose production and utilisation." British Medical Journal. 1978;1:1239-1242. Abstract

Six insulin-requiring diabetics were studied after insulin had been withheld for 24 hours. On three separate occasions each received a two-hour infusion of insulin at a low dose (2.6 U/h) and a high dose (10.6 U/h) and an infusion of saline as control. The rates of production and utilisation of glucose were measured isotopically. The rate of fall of plasma glucose concentration was faster on the high-dose infusion of insulin than on the low, whereas the fall in plasma free fatty acids, glycerol, and keton bodies was the same on both insulin infusions. The mechanism whereby the two rates of insulin administration lowered plasma glucose concentration differed: during the low-dose infusion the decrease in the glucose concentration was produced entirely by a fall of hepatic glucose output, whereas during the high-dose insulin infusion the glucose concentration fell because both the rate of glucose production fell and the rate of glucose utilisation rose. In all experiments there was a direct relation between a fall in serum potassium concentration and the fall in plasma glucose concentration irrespective of the mechanism that reduced the glucose concentration.These results indicate that in uncontrolled diabetics low-dose insulin infusions lower the blood glucose concentration entirely by reducing glucose production from the liver and that the effect of insulin on potassium transport is independent of its effect on glucose uptake.

Simanovskaia VK, Kadishaite DL, Lisok TP, Siminina AA, Goluveb DB. "[Characterization of biological properties and glycopeptide composition of influenza virus type A grown in different cell systems]." Virologie. 1978;29(4):275-81.
Gripenberg U, Saarinen I, Bwibo NO, Oduori ML, Grayburn JA, Awori NW, Wasunna AE, Kinuthia DM. "Two true hermaphrodites with XX chromosomes." East Afr Med J. 1978;55(8):373-9.
S PROFOLIECHJOSEPH. "Carcinoma of thyroid at KNH Assoc. of Surgeons of E.A. proceedings Dec. 1978.". In: East Afr Med J. 1979 Jan;56(1):40-1. PROF.J.S.OLIECH; 1978. Abstract

No abstract available yet.ABSTRACT.

This a report of thirty patients who presented at Kenyatta National Hospital( KNH),Uinversity Of Nairobi (UON) during the three year period January 1974-December 1976 with a diagnosis of thyroid carcinoma.Fourteen had follicular, eight papiilary,four anaplastic,and four medullary types.
Eight patients had metastatic deposits in lymph nodes,lung,or bone and majority of these were anaplastic.Twenty patients received surgical treatment.Five total thyroidectomy, 12 had subtotal thyroidectomy,3 had hemithyroidectomy and 2 had radioactive iodine treatment without surgery.
Most patients received subtotal thyroidectomy with or without radiotherapy. The anaplastic cancers had the poorest prognosis, all dying within six months of diagnosis.Early diagnosis with frozen section the papillary/follicular possess good prognosis if appropriate surgical treatment of subtotal or hemithyroidectomy is done.

Ochoro WE, Stoneman P. "A Means Variance Approach to the theory of Diffusion.". In: Warwick department of Economics, mimeos.; 1978.
Sketchley HR, Mbuvi JP, Scilley FM, Wokobi SM. "Soil science [in the Marginal Semi-Arid Lands of Kenya].". 1978.
Sketchley HR, Scilley FM, Wokobi SM. "Soil science [in the Marginal Semi-Arid Lands of Kenya].". 1978.Website
S. PROFNTEEREJACOB. "Advanced Diploma Dissertation entitled "A study of the Curricula of Physical Education of Primary Teachers Colleges in Kenya" (University of Leeds, in 1978).". In: Seminar, University of Manchester, 1981. Institute of African Studies, University of Nairobi; 1978. Abstract
Introduction The Centre for Open and Distance Learning has been established to facilitate the Internal Faculties in launching and managing their programmes using distance mode with a view to increasing access to university education and provide equity in higher education to the learners all over the country. Operational Strategies The operational strategies that have been set up involve collaborative arrangements between the CODL and the Internal Faculties in the development of Study Materials and Learner support Services for off-campus students. The professional in open and distance learning are availed by the Centre to serve the Faculties as trainers while the Faculties provide academic expertise who are facilitated through participatory methods involving application of knowledge, skills and strategies to develop study materials in their respective subjects. Focus The Centre is currently working with Faculties of Science, Commerce and Arts. The Material development process involves training, writing, reviewing and editing followed by conversion to e-content and audio modes. Conclusion These collaborative arrangements will increase access to higher education make significant contribution in the realization of educational Millennium Goals in Kenya where only 20% of all those who qualify obtain admission in the public universities.
S. PROFMBINDYOBENJAMIN. "Mbindyo, B.S. Lower limb amputations at the Kenyatta National Hospital, E.A.M.J. vol 55, No. 10 Oct. 1978.". In: E.A.M.J. vol 55, No. 10 Oct. 1978. University of Nairobi.; 1978. Abstract
Kenya is a country of marked environmental and ethnic diversity. A study of osteogenic sarcoma occurring in Kenya from 1968 to 1978 revealed 251 cases, representing between 89% and 100% of the predicted number. Variations in age, sex and anatomical location were within classical limits. However, the incidence of osteogenic sarcoma amongst the Central Bantu was significantly higher than predicted (P less than 0.0001), whilst the incidence among the Western Bantu was significantly lower (P less than 0.002), despite their similar ethnic origins. Two geographically dissimilar areas likewise exhibited significant differences in incidence. The Eastern province showed a higher incidence (P less than 0.02), whereas the Nyanza Province (P less than 0.001) and the adjacent Western Province (P less than 0.005) showed a lower than predicted incidence. These observations suggest that in Kenya a geomedical variable affects the incidence of osteogenic sarcoma and that genetic variation has no effect on incidence.
S. PROFMBINDYOBENJAMIN. "Mbindyo, B.S.Considerations on Cases of epiphyseal injury observed at the Kenyatta National Hospital E.A.M.J. vol. 56 No. 9 Sept. 1978.". In: E.A.M.J. vol. 56 No. 9 Sept. 1978. University of Nairobi.; 1978. Abstract
Kenya is a country of marked environmental and ethnic diversity. A study of osteogenic sarcoma occurring in Kenya from 1968 to 1978 revealed 251 cases, representing between 89% and 100% of the predicted number. Variations in age, sex and anatomical location were within classical limits. However, the incidence of osteogenic sarcoma amongst the Central Bantu was significantly higher than predicted (P less than 0.0001), whilst the incidence among the Western Bantu was significantly lower (P less than 0.002), despite their similar ethnic origins. Two geographically dissimilar areas likewise exhibited significant differences in incidence. The Eastern province showed a higher incidence (P less than 0.02), whereas the Nyanza Province (P less than 0.001) and the adjacent Western Province (P less than 0.005) showed a lower than predicted incidence. These observations suggest that in Kenya a geomedical variable affects the incidence of osteogenic sarcoma and that genetic variation has no effect on incidence.
SAMSON PROFMEMEJULIUS. "Meme J. S. A prospective study of Neonatal deaths in Nairobi Kenya E. Afr. Med. J. 55: 264, 1978.". In: Kenya E. Afr. Med. J. 54: 44, 1977. au-ibar; 1978. Abstract
No abstract available
S. PROFNTEEREJACOB. "PROF. JACOB STANLEY NTEERE, DR. WANDERI & JANET W. KAMENJU, AEROBIC CAPACITY OF KENYAN RUGBY UNION PLAYERS.". In: Seminar, University of Manchester, 1981. Institute of African Studies, University of Nairobi; 1978.
S. PROFEL-BUSAIDYABDULGAFURH. "The Role of Concrete Cover on Corrosion of the Reinforcement". NUCC, Vol.1 No.". In: Kenya. J. Kenya Meteorological Soc; 1978. Abstract
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SHAWKY PROFROSTOMRAOUF, SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1978: Remote Sensing for Development, an invited paper at the Seminar of Surveyors in Kenya, Nairobi.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1978.
S. PROFEL-BUSAIDYABDULGAFURH. "Simulation of the Electrolytic Conditions in Concrete by use of saturated CA (OH) Solutions".". In: Trondheim, Norway. J. Kenya Meteorological Soc; 1978. Abstract
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SAMUEL PROFKIBICHO. ""The continuity of the African conception of God into and through Christianity," Christianity in Independent Africa, ed. Fashole - Luke and others (London: Rex Collings.". In: Proceedings of 3rd Int. Conf. On bearing capacity of roads and airfields PP 743-756, Trondeihm, Norway. Longhorn; 1978. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
S PROFOLIECHJOSEPH. "Urethral strictures, treatment by one stage urethroplasty. (press).". In: East Afr Med J. 1979 Jan;56(1):40-1. PROF.J.S.OLIECH; 1978. Abstract
No abstract available yet.
1977
Saeki N, Rhoton AL. "Microsurgical anatomy of the upper basilar artery and the posterior circle of {Willis}." Journal of Neurosurgery. 1977;46:563-578. AbstractWebsite
n/a
Hickey TL, Spear PD, Kratz KE. "Quantitative studies of cell size in the cat's dorsal lateral geniculate nucleus following visual deprivation." The Journal of comparative neurology. 1977;172:265-281. Abstract

The effects of visual deprivation upon dorsal lateral geniculate (DLG) cell size were compared for seven kittens reared with monocular lid-suture (MD), seven with binocular lid-suture (BD), and six with one eye lid-sutured and the other eye enucleated soon after birth (MD-E). Six additional kittens were reared normally for comparison. For each kitten the cross-sectional areas of 300 cells were measured in one or both nuclei. Measurements were taken from the binocular segment of laminae A and A1 and the monocular segment of lamina A. In agreement with previous studies, cells in the binocular segment of the deprived laminae of MD cats were smaller (33-34%) than those in the non-deprived laminae. Comparisons with normal animals indicated that this difference was due to an increase (10-15%) in size of cells in the non-deprived laminae as well as a decrease (23-25%) in size of cells in the deprived laminae. Cells in the monocular segment also were affected by deprivation in MD cats, and this effect increased with the age (and duration of the deprivation) of the animal. However, it was always smaller than the decrease in cell size in the binocular portion of the DLG. In BD kittens, DLG cells were smaller (7-12%) than normal in all portions of the nucleus, including both the binocular and monocular segments. Direct comparisons between the deprived laminae of MD and BD kittens indicated that the decrease in cell size was greater for MD kittens in the binocular segment, but tended to be greater for BD kittens in the monocular segment. In MD-E kittens, DLG cells in the deprived laminae were smaller (11-17%) than normal in all portions of the nucleus, including both the binocular and monocular segments. Thus, the effects of deprivation were similar to those in BD kittens, even though inputs from the deprived eye had been placed at a competitive advantage in MD-E kittens. These results indicate that two factors may affect cell size in the DLG of visually deprived cats: deprivation per se and abnormal binocular competition. Finally, separate analyses for the ten largest and the ten smallest cells in each lamina of each cat were carried out in an attempt to determine if the changes in cell size were limited to the largest cells. In every case, differences observed for the total sample of cells were paralleled by differences from normal of both the largest cells present and the smallest cells present in the deprived laminae. Since at least two alternative interpretations can account for this finding, the question of whether the large cells are selectively affected by visual deprivation remains unanswered in the cat.

Fisher JN, Shahshahani MN, Kitabchi AE. "Diabetic ketoacidosis: low-dose insulin therapy by various routes." The New England Journal of Medicine. 1977;297:238-241. Abstract

Since in normal persons the hypoglycemic effect of low-dose intramuscular exceeds that of subcutaneous insulin we studied the effect of routes of insulin therapy in diabetic ketoacidosis. Forty-five patients with diabetic ketoacidosis entered a randomized prospective protocol with insulin administered either intravenously, subcutaneously or intramuscularly. Initial priming dose of insulin had to be repeated in two of 15, three of 15 and six of 15 of the intravenous, subcutaneous and intramuscular groups respectively. The intravenous group had a more rapid fall in plasma glucose (P less than 0.01) and ketone bodies (P less than 0.05) during the first two hours. Thereafter, there were no significant differences in the rate of decline of plasma glucose or ketones nor in the time required for glucose to reach 250 mg per deciliter or for complete recovery from diabetic ketoacidosis. The data confirm the efficacy of low-dose insulin therapy for diabetic ketoacidosis and indicate that the optimal route of insulin administration is by initial intravenous combined with subcutaneous or intramuscular.

Terayama Y, Kaneko Y, Kawamoto K, Sakai N. "Ultrastructural changes of the nerve elements following disruption of the organ of {Corti}. {I}. {Nerve} elements in the organ of {Corti}." Acta oto-laryngologica. 1977;83:291-302. Abstract

3-137 days after disruption of the guinea pig organ of Corti by perilymphatic perfusion with 20% streptomycin (SM), ultrastructural changes of the nerve fibers in the organ were observed. Most of nerve fibers began to degenerate after a latent period of 4 days. On the other hand, a number of fibers survived reactively enlarged and later developed into myelinated and unmyelinated fibers by becoming enclosed in Schwann cells which entered the organ of Corti through the habenula perforata. Regeneration and sprouting of the surviving nerve fibers also occurred. The fibers became mature, but atrophied after 60 days and then gradually disappeared. The regenerating fibers were mainly of the myelinated and unmyelinated efferent type. Retrograde degeneration occurred in both afferent and efferent fibers. In the less damaged organ of Corti perfused with 2% SM or Ringer's solution, Schwann cell invasion was not found.

Steel CM, Ennis M, Levin AG, Wasunna A. "The mitogenic response of cryopreserved human lymphocytes in a microculture system." Cytobios. 1977;18(70):89-99. Abstract

Fresh blood lymphocytes from nine health donors have been compared with samples from the same donors, recovered after period of 2 to 21 months storage in liquid nitrogen, for the capacity to respond to a range of mitogens in vitro. A microculture assay was used, requireing aliquots of only 25,000 cells. The mean levels of 14C-thymidine uptake for fresh and frozen samples were closely comparable when the cells had been stimulated by PHA, Pokeweed or mitomycin-C-treated allogeneic lymphoblastoid cells. Lymphocytes from six East African donors, frozen by a very simple technique, were recovered after 3 or more years storage in liquid nitrogen. Five of the samples were in good condition as judged by cell viability and the capacity to form spontaneous 'E' rosettes with sheep erythrocytes. These five samples also responded extremely well to PHA, PWM and mitomycin-C-treated allogeneic lymphoblastoid cells using the microculture assay. This study extends the range of applications of cell banks in which small aliquots of blood lymphocytes are stored in liquid nitrogen for periods of several years.

Ogana W, Spreiter JR. "Derivation of an integral equation for transonic flows." AIAA Journal. 1977;Vol. 15(No. 2):pp. 281-282.
SAMSON PROFMEMEJULIUS. "Cryptogenic fibrosing alveolitis. (Case report of a child). East Afr Med J. 1977 Jan;54(1):43-6. Meme JS, Clogg DK, Gatei D, Lewis C.". In: East Afr Med J. 1977 Jan;54(1):43-6. au-ibar; 1977. Abstract
No abstract available.
STEVE DRNANGENDO. "The dead people of Njoro.". In: Reappraisal of Hromniks's Articles. IBIMA Publishing; 1977. Abstract
While the role of logistics and supply chain management in developing competitive business capabilities is beginning to be recognized by many global organizations, there is critical need to ensure that training institutions do their part in imparting market-driven skills to prospective and existing practitioners. The role and importance of supply chain management has largely been attributed to the effects of globalization, intensifying competition and an increasing emphasis on customer orientation (Gunasekaran et al., 2004; Webster, 2002). Against this backdrop, effective supply chain management is considered key to building a sustainable competitive edge through improved inter and intra-firm relationships (Ellinger, 2000).
S. PROFEL-BUSAIDYABDULGAFURH. "Electrical Resistivity of Concrete in the Oceans". Paper No.2803 pp 581-588.". In: Houston, Texas. J. Kenya Meteorological Soc; 1977. Abstract
     
S PROFOLIECHJOSEPH. "Intravenous Feeding in General Surgery. E.A. Med. J. Vol. 54 No. 1, 1977.". In: E.A. Med. J. Vol. 54 No. 1, 1977. PROF.J.S.OLIECH; 1977. Abstract
No abstract yet.
S PROFKIGONDUCHRISTINE. "Lutalo-Bosa A.J., Sekadde C.B., Opiyo W. and Kiwanuka J.B., Presentation of paper to the Annual Scientific Conference of East Africa Medical Research Council, February, 1977 Liver function tests among normal Ugandans. A paper was reported in the Annual Re.". In: Annual Scientific Conference of East Africa Medical Research Council. uon press; 1977. Abstract

PIP: Masturbatory semen specimen from 49 fertile Black African males in Kenya whose wives were pregnant was obtained after at least 3 days of abstinence for the analysis of parameters which included volume motility, vitality, sperm concentration, pH, fructose and acid phosphatase levels. About 1/2 the spermatozoa was actively progressive in motility, while 40% was nonmotile. Vitality in the 1st hour revealed that 81.4% of the sperm was alive. About 90% of the semen specimens had more than 40% idea forms of spermatozoa. Spermatozoal abnormalities were a frequent feature. There was no correlation between age and the testicular volume, but seminal fluid volume and sperm density tended to decrease with age. Serum levels of Follicle Stimulating Hormone, Luteinizing Hormone, Prolactin and Testosterone were determined in the subjects' sera, enabling the establishment of reference values for these parameters in African Kenyan males.

STEVE DRNANGENDO. "Material culture.". In: Micro- and Macro-level interactions Among Babukusu in Bungoma District. IBIMA Publishing; 1977. Abstract
While the role of logistics and supply chain management in developing competitive business capabilities is beginning to be recognized by many global organizations, there is critical need to ensure that training institutions do their part in imparting market-driven skills to prospective and existing practitioners. The role and importance of supply chain management has largely been attributed to the effects of globalization, intensifying competition and an increasing emphasis on customer orientation (Gunasekaran et al., 2004; Webster, 2002). Against this backdrop, effective supply chain management is considered key to building a sustainable competitive edge through improved inter and intra-firm relationships (Ellinger, 2000).
SAMSON PROFMEMEJULIUS. "Meme J. S., Clogg, D.K., Gatei D., Lewis C., Cryptogenic Fibrosing alvelitis. E. Afr. Med. J. 54: 44, 1977.". In: E. Afr. Med. J. 54: 44, 1977. au-ibar; 1977. Abstract
No abstract available.
SAMSON PROFMEMEJULIUS. "Meme J. S., Hillman D. Infants of low birth weight seen at the Kenyatta National Hospital E. Afr. Med. J. 54: 28, 1975.". In: E. Afr. Med. J. 54: 28, 1977. au-ibar; 1977. Abstract
No abstract available.
S PROFKIGONDUCHRISTINE. "Papine J., Lutalo-Bosa A.J., Sekadde C.B. Reported in the Annual Report of Scientific Conference of the East African Medical Research Council, 1977. The Effect of Halothane on the levels of serum proteins.". In: Annual Report of Scientific Conference of the East African Medical Research Council. uon press; 1977. Abstract

PIP: Masturbatory semen specimen from 49 fertile Black African males in Kenya whose wives were pregnant was obtained after at least 3 days of abstinence for the analysis of parameters which included volume motility, vitality, sperm concentration, pH, fructose and acid phosphatase levels. About 1/2 the spermatozoa was actively progressive in motility, while 40% was nonmotile. Vitality in the 1st hour revealed that 81.4% of the sperm was alive. About 90% of the semen specimens had more than 40% idea forms of spermatozoa. Spermatozoal abnormalities were a frequent feature. There was no correlation between age and the testicular volume, but seminal fluid volume and sperm density tended to decrease with age. Serum levels of Follicle Stimulating Hormone, Luteinizing Hormone, Prolactin and Testosterone were determined in the subjects' sera, enabling the establishment of reference values for these parameters in African Kenyan males.

STEVE DRNANGENDO. "A preliminary report of the contemporary ceramic industry of Babukusu.". In: In the Petrological investigations of Prehistoric pottery in Kenya. IBIMA Publishing; 1977. Abstract
While the role of logistics and supply chain management in developing competitive business capabilities is beginning to be recognized by many global organizations, there is critical need to ensure that training institutions do their part in imparting market-driven skills to prospective and existing practitioners. The role and importance of supply chain management has largely been attributed to the effects of globalization, intensifying competition and an increasing emphasis on customer orientation (Gunasekaran et al., 2004; Webster, 2002). Against this backdrop, effective supply chain management is considered key to building a sustainable competitive edge through improved inter and intra-firm relationships (Ellinger, 2000).
SHAWKY PROFROSTOMRAOUF, SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1977: Teaching of Surveying at the University of Nairobi, presented paper at the inaugural meeting of the Geodetic Commission for Africa, Lagos, April 1977.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1977.
1976
Silverstein E, Friedland J, Lyons HA, Gourin A. "Markedly elevated angiotensin converting enzyme in lymph nodes containing non-necrotizing granulomas in sarcoidosis." Proc. Natl. Acad. Sci. U.S.A.. 1976;73(6):2137-41. Abstract

Sarcoidosis is a disease of unknown etiology that is characterized by the generalized formation of granulomas and is accompanied by elevation in the serum in less than half the patients of angiotensin converting enzyme, a dipeptidyl carboxypeptidase that catalyzes the conversion of the decapeptide, angiotensin I, to the pressor octapeptide, angiotensin II, and L-histidyl-L-leucine. Mean activity of angiotensin converting enzyme was elevated generally more than 10-fold in granuloma-containing lymph nodes, but not in lung in which normally it is abundant, in 19 of 20 patients with sarcoidosis. Angiotensin converting enzyme in lymph nodes from subjects with sarcoidosis was similar to the enzyme from normal lung and lymph node with respect to activity as a function of pH, inhibition of activity by EDTA and o-phenanthroline, gel filtration on Sephadex G-200, and requirement for chloride for activity, but appeared to be more heat labile. The data suggest that the granulomas in sarcoidosis may be the source of the elevated serum enzyme and that cells of the granulomas, particularly the epitheloid cells which appear by electron microscopy to have active protein biosynthesis, may be actively synthesizing the enzyme.

Stamm O, Latscha U, Janecek P, Campana A. "Development of a special electrode for continuous subcutaneous pH measurement in the infant scalp." Am. J. Obstet. Gynecol.. 1976;124(2):193-5. Abstract

Using a combined special glass electrode it is possible to monitor pH ratios and pH variation in the subcutaneous tissue of the infant scalp continuously. Tests on a normal sample of newborn babies immediately after birth showed a significant correlation between tissue pH and capillary blood pH, with the trend of pH variation being broadly similar in both measurement media.

Stamm O, Latscha U, Janecek P, Campana A. "Development of a special electrode for continuous subcutaneous pH measurement in the infant scalp." Am. J. Obstet. Gynecol.. 1976;124(2):193-5. Abstract

Using a combined special glass electrode it is possible to monitor pH ratios and pH variation in the subcutaneous tissue of the infant scalp continuously. Tests on a normal sample of newborn babies immediately after birth showed a significant correlation between tissue pH and capillary blood pH, with the trend of pH variation being broadly similar in both measurement media.

Stamm O, Latscha U, Janecek P, Campana A. "Development of a special electrode for continuous subcutaneous pH measurement in the infant scalp." Am. J. Obstet. Gynecol.. 1976;124(2):193-5. Abstract

Using a combined special glass electrode it is possible to monitor pH ratios and pH variation in the subcutaneous tissue of the infant scalp continuously. Tests on a normal sample of newborn babies immediately after birth showed a significant correlation between tissue pH and capillary blood pH, with the trend of pH variation being broadly similar in both measurement media.

Share JB. "Review of drug treatment for Down's syndrome persons." Am J Ment Defic. 1976;80(4):388-93. Abstract

A review of drug treatment for Down's syndrome individuals was presented. Drugs used to modify behavior, as well as drugs used with the goal of affecting cognitive processes, were discussed. Some observations were offered as to the effectiveness of past and current drugs on Down's syndrome and some methodological problems relating to drug studies presented. There have not been any drugs that have demonstrated remarkable improvement in the status of Down's syndrome individuals that have been widely accepted as effective.

Share JB. "Review of drug treatment for Down's syndrome persons." Am J Ment Defic. 1976;80(4):388-93. Abstract

A review of drug treatment for Down's syndrome individuals was presented. Drugs used to modify behavior, as well as drugs used with the goal of affecting cognitive processes, were discussed. Some observations were offered as to the effectiveness of past and current drugs on Down's syndrome and some methodological problems relating to drug studies presented. There have not been any drugs that have demonstrated remarkable improvement in the status of Down's syndrome individuals that have been widely accepted as effective.

Okwaro HW, Mbuvi JP, Sombroek WG. "Soils of semi-arid savanna zone of the north-eastern Kenya : site evaluation report.". 1976. Abstract

Recent ground observation and study of ERTS imagery, in connection with national programme for country-wide soils mapping at scale 1: 1,000,000, have yielded substantial new information on the nature and distribution of the soils in the savanna-covered semi-arid plains of the North-Eastern Kenya. The findings differ in several aspects from earlier schematic mapping, notably in the near absence of well-drained calcerous soils and the wide extent of saline/alkali soils in the central-eastern section. The origin of the different soils development at the various geomorphologic levels is discussed, in relation to the character of the sediments as well as the quaternary changes in climate. Also, an outline is given of the significance of such exploratory mapping, on physiographic basis, for the sound planning of range management, wildlife conservation and irrigation development in the area.

S. PROFEL-BUSAIDYABDULGAFURH. "Assessment of Physical Changes and Natural System Responses;.". In: Nairobi. J. Kenya Meteorological Soc; 1976. Abstract
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S. PROFEL-BUSAIDYABDULGAFURH. "Diffusion of Dissolved Oxygen through Concrete". Presented at the National Association of Corrosion Engineers Conference, Corrosion 76,.". In: Houston, Texas. J. Kenya Meteorological Soc; 1976. Abstract
     
S DRKARANJAHDOMINIC. "Karanja D. S .". In: The Limnology, Climatology and Palaeoclimatology of the East African Lakes pp. 413-431, Gordon and Breach Publishers, Amsterdam. June 1996 b) Books Reference Date. Earthscan, London. 978-1-84407-469-3 (*); 1976. Abstract
n/a
SHAWKY PROFROSTOMRAOUF, SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1976: Elements of Surveying for Civil Engineers, A textbook for Civil Engineering students, (in Arabic).". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1976.
SHAWKY PROFROSTOMRAOUF, SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1976: The use of Photogrammetry for Geographical Development, invited paper at the Second Arabic Geographic Conference, Baghdad, March 1976.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1976.
S. PROFEL-BUSAIDYABDULGAFURH. "The Survey of the Extent of Corrosion Problems in Kenya". Final Report to the National Council for Science & Technolog.". In: Houston, Texas. J. Kenya Meteorological Soc; 1976. Abstract
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S. PROFEL-BUSAIDYABDULGAFURH. "X-Ray Fluorescence Analysis (XRF) of Trace Elements in Tuff (Volcanic Soil) and in Tissues of Rats fed with Tuff.". In: Nairobi. J. Kenya Meteorological Soc; 1976. Abstract
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1975
Powner D, Snyder JV, Grenvik A. "Altered pulmonary capillary permeability complicating recovery from diabetic ketoacidosis." Chest. 1975;68:253-256. Abstract

Self-limited noncardiogenic interstitial pulmonary edema probably reflecting altered permeability of the pulmonary capillary membrane is reported in a patient being treated for severe diabetic ketoacidosis. The possible etiology, associated findings, and therapy with continuous positive airway pressure (CPAP) by facemask are discussed.

Ostashevskiĭ II, Sungurov IA, Volchkov VA. "[Light scattering by cell suspensions in normal conditions and exposed to external factors]." Biofizika. 1975;20(5):853-8. Abstract

The characteristics of light scattering of cell suspensions in norm (pH 7,2, t=20degreesC) and upon external influences (change of pH and increase of tdegree). The turbidity tauapproximatelylambda-n and n=0,2--0,3 for cells in norm. After cell damage n increases. Dependence of n correlates with the increase of some injured cells determined by eozin test. Alterations of light scattering after cell damage were connected with the increase of deposit of intercellular structure in general scattering.

Schmoldt A, Benthe HF, Haberland G. "Digitoxin metabolism by rat liver microsomes." Biochem. Pharmacol.. 1975;24(17):1639-41.
Schmoldt A, Benthe HF, Haberland G. "Digitoxin metabolism by rat liver microsomes." Biochem. Pharmacol.. 1975;24(17):1639-41.
Silen W, Machen TE, Forte JG. "Acid-base balance in amphibian gastric mucosa." Am. J. Physiol.. 1975;229(3):721-30. Abstract

It has been established that H+ secretion can be maintained in frog stomach in the absence of exogenous CO2 by using a nutrient bathing fluid containing 25 mM H2PO4 (pH approximately equal to 4.5) or by lowering the pH of a nonbuffered nutrient solution to about 3.0-3.6. Exogenous CO2 in the presence of these nutrient solutions uniformly caused a marked decrease in H+ secretion, PD, adn short-circuit current (Isc) and an increase in transmucosal resistance (R). Elevation of nutrient [k+] to 83 mM reduced R significantly but transiently without change in H+ when nutrient pH less than 5.0, whereas R returned to base line and H+ increased when nutrient pH greater than 5.0. Acidification of the nutrient medium in the presence of exogenous CO2 results in inhibition of the secretory pump, probably by decreasing intracellular pH, and also interferes with conductance at the nutrient membrane. Removal of exogenous CO2 from standard bicarbonate nutrient solution reduced by 50% the H+, PD, and Isc without change in R; K+-free nutrient solutions reverse these changes in Isc and PD but not in H+. The dropping PD and rising R induced by K+-free nutrient solutions in 5% CO2 - 95% O2 are returned toward normal by 100% O2. Our findings support an important role for exogenous CO2 in maintaining normal acid-base balance in frog mucosa by acting as an acidifying agent.

Scherberger RR, Kaess H, Brückner S. "[Studies on the action of an anticholinergic agent in combination with a tranquilizer on gastric juice secretion in man]." Arzneimittelforschung. 1975;25(9):1460-3. Abstract

A double-blind study with intra-individual comparisons was carried out to investigate the effects of 15 mg of (8r)-3alpha-hydroxy-8-isopropyl-1alphaH-tropanium bromide(+/-)-tropate (Sch 1000), 15 mg Sch 1000 + 10 mg oxazepam, 10 mg oxazepam and placebo with oral administration in randomized sequence on gastric juice volume, amount of acid, concentration and pH values in 12 healthy volunteers. The secretion parameters were measured during a 1-h basal period and a 2-h stimulation period. The gastric juice was obtained in 15 min portions via stomach tube. Stimulation was effected by 1 mug/kg/h pentagastrin via drip infusion. The Friedman test was used for the comparative statistical evaluation, and individual comparisons were carried out by means of the Wilcoxon test (pair-differences rank). The results show that Sch 1000 and Sch 1000 + oxazepam were equal in effect on basal and stimulated secretion volume. As compared with placebo, it was not possible to establish an effect on secretion volume for oxazepam alone. Sch 1000 and Sch 1000 + oxazepam were found to be equipotent in reducing the amount of basal acid, while oxazepam reduced this quantity only during the first 30 min of basal secretion. None of the three active preparations was capable of inhibiting the stimulated acid, although both Sch 1000 preparations produced a clear trend towards lowered mean values. During the basal secretion period, all three test preparations had an inhibiting action on acid concentration, but none of them had a significant effect during the stimulation period. The pH value was savely increased only by Sch 1000 and Sch 1000 + oxazepam, and this even only during the basal period. The results are discussed.

Smith RJ, Bryant RG. "Metal substitutions incarbonic anhydrase: a halide ion probe study." Biochem. Biophys. Res. Commun.. 1975;66(4):1281-6.
Smith RJ, Bryant RG. "Metal substitutions incarbonic anhydrase: a halide ion probe study." Biochem. Biophys. Res. Commun.. 1975;66(4):1281-6.
Lorkin PA, Stephens AD, Beard ME, Wrigley PF, Adams L, Lehmann H. "Haemoglobin Rahere (beta Lys-Thr): A new high affinity haemoglobin associated with decreased 2, 3-diphosphoglycerate binding and relative polycythaemia." Br Med J. 1975;4(5990):200-2. Abstract

A new haemoglobin with increased oxygen affinity, beta82 (EF6) lysine leads to threonine (Hb Rahere), was found during the investigation of a patient who was found to have a raised haemoglobin concentration after a routine blood count. The substitution affects one of the 2, 3-diphosphoglycerate binding sites, resulting in an increased affinity for oxygen, but both the haem-haem interaction and the alkaline Bohr effect are normal in the haemolysate. This variant had the same mobility as haemoglobin A on electrophoresis at alkaline pH but was detected by measuring the whole blood oxygen affinity; it could be separated from haemoglobin A, however, by electrophoresis in agar at acid pH. The raised haemoglobin concentration was mainly due to a reduction in plasma volume (a relative polycythaemia) and was associated with a persistently raised white blood count. This case emphasises the need to measure the oxygen affinity of haemoglobin in all patients with absolute or relative polycythaemia when some obvious cause is not evident.

Theodor JL, Senelar R. "Cytotoxic interaction between gorgonian explants: mode of action." Cell. Immunol.. 1975;19(2):194-200.
Yoshimura F, Suzuki T. "Calcium-stimulated adenosine triphosphatase in the microsomal fraction of tooth germ from porcine fetus." Biochim. Biophys. Acta. 1975;410(1):167-77. Abstract

The characterization and localization of a Ca(2+)-ATPase (ATP phosphohydrolase, EC 3.6.1.3) in the tooth germ of the porcine fetus are reported. This enzyme, a microsome fraction, is preferentially activated by Ca(2+). In the presence of 0.5 mM ATP, maximal enzyme activity is obtained at 0.5--1.0 mM CaCl2. The maximal rate of ATP hydrolysis is approx. 20 mumol per h per mg of protein as the enzyme preparation is used here. At optimal Ca(2+) concentration, the Mg(2+) has an inhibitory effect. The enzyme does not require Na+ or/and K+ for activation by Ca(2+). Other nucleotide triphosphates may serve as the substrate, but V for ATP is the highest. The Km for ATP is 8.85 - 10(-5) M. The optimal pH for Ca(2+) activation of the enzyme lies around 9.2. Well known inhibitors of (Na+ + K+)-ATPase, mitochondria ATPase and Ca(2+)-ATPase in the erthrocyte do not inhibit the enzyme. In the subcellular order the enzyme may be assumed to be localized in the smooth endoplasmic reticulum fraction containing cell and Golgi body membrane fragments and in the tissue order in the enamel organ containing an ameloblast layer, stratum intermedium and stellate reticulum.

Stellwagen E, Babul J. "Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents." Biochemistry. 1975;14(23):5135-40. Abstract

Increasing concentrations of chloride were found to increase the resolution between two visible absorbance spectral transitions associated with acidification of ferricytochrome c. Analysis of a variety of spectral and viscosity measurements indicates that protonation of a single group having an apparent pK of 2.1 +/- 0.2 and an intrinsic pK of about 5.3 displaces the methionine ligand without significantly perturbing the native globular conformation. Analysis of methylated ferricytochrome c suggests that protonation of a carboxylate ion, most likely a heme propionate residue, is responsible for displacement of the methionine ligand. Addition of a proton to a second group having an apparent pK of 1.2 +/- 0.1 displaces the histidine ligand and unfolds the protein from a globular conformation into a random coil. It is most likely that the second protonation occurs on the imidazole ring of the histidine ligand itself. Chloride is proposed to perturb these transitions by ligation in the fifth coordination position of the heme ion. Such ligation stabilizes a globular conformation of ferricytochrome c at pH 0.0 and 25 degrees.

Scheller F, Jänchen M, Lampe J, Prümke HJ, Blanck J, Palecek E. "Studies on electron transfer between mercury electrode and hemoprotein." Biochim. Biophys. Acta. 1975;412(1):157-67. Abstract

The electrochemical behaviour of ferricytochrome c, metmyoglobin and methemoglobin was studied using d.c., a.c. and differential pulse polarography, and controlled potential electrolysis. 1. The three hemoproteins yield d.c. polarographic steps, and peaks in differential pulse polarograms, the height of which is proportional to concentration. The charge transfer is influenced by strong adsorption. 2. The concentration dependence of the a.c. polarograms indicates structural changes in the adsorbed molecules. 3. The reduction products of controlled potential electrolysis of metmyoglobin and methemoglobin have absorption spectra identical with the native control samples. The affinity for oxygen and the cooperativity in hemoglobin are not affected by the reaction at the electrode. 4. The charge transfer proceeds via adsorbed, already reduced, molecules to freely diffusible proteins.

Hirano H, Higashi K, Sakamoto Y. "DNA polymerase in nuceoli isolated from Ehrlich ascites tumor cells." Biochem. Biophys. Res. Commun.. 1975;67(2):518-24.
Sprenger KJ, Chouler CA. "The GP dilemma. Recommendations and synopsis of a student conference." S. Afr. Med. J.. 1975;49(49):2059-60. Abstract

The proceedings of a conference organised by students are reported. The present standing of the general practitioner and his need in different societies are equated and the obvious deficiencies are considered. Such themes as maldistribution, service and education are discussed. Resolutions derived from the conference are reported in full.

Shanmugam KT, Chan I, Morandi C. "Regulation of nitrogen fixation. Nitrogenase-derepressed mutants of Klebsiella pneumoniae." Biochim. Biophys. Acta. 1975;408(2):101-11. Abstract

1. A new procedure is described for selecting nitrogenase-derepressed mutants based on the method of Brenchley et al. (Brenchley, J.E., Prival, M.J. and Magasanik, B. (1973) J. Biol. Chem. 248, 6122-6128) for isolating histidase-constitutive mutants of a non-N2-fixing bacterium. 2. Nitrogenase levels of the new mutants in the presence of NH4+ were as high as 100% of the nitrogenase activity detected in the absence of NH4+. 3. Biochemical characterization of these nitrogen fixation (nif) derepressed mutants reveals that they fall into three classes. Three mutants (strains SK-24, 28 and 29), requiring glutamate for growth, synthesize nitrogenase and glutamine synthetase constitutively (in the presence of NH4+). A second class of mutants (strains SK-27 and 37) requiring glutamine for growth produces derepressed levels of nitrogenase activity and synthesized catalytically inactive glutamine synthetase protein, as determined immunologically. A third class of glutamine-requiring, nitrogenase-derepressed mutants (strain SK-25 and 26) synthesizes neither a catalytically active glutamine synthetase enzyme nor an immunologically cross-reactive glutamine synthetase protein. 4. F-prime complementation analysis reveals that the mutant strains SK-25, 26, 27, 37 map in a segment of the Klebsiella chromosome corresponding to the region coding for glutamine synthetase. Since the mutant strains SK-27 and SK-37 produce inactive glutamine synthetase protein, it is concluded that these mutations map within the glutamine synthetase structural gene.

Sádecký E, Brezina R, Kazár J, Urvölgyi J. "Immunization against Q-fever of naturally infected dairy cows." Acta Virol.. 1975;19(6):486-8. Abstract

Dairy cows infected naturally with Coxiella burnetii as evidenced either by presence of phase II agglutinating antibodies in the blood or by shedding C. burnetii in the milk, were vaccinated subcutaneously with formalin-killed phase I C. burnetii organisms. Attempts to demonstrate C. burnetii in the milk of vaccinated dairy cows 47 days after vaccination were negative, while continuous shedding of C. burnetii in the milk of control non-vaccinated dairy cows was repeatedly demonstrated in the course of 123 days (period of investigation). No harmful systemic reaction following vaccination was observed.

Stites DP, Caldwell J, Carr MC, Fudenberg HH. "Ontogeny of immunity in humans." Clin. Immunol. Immunopathol.. 1975;4(4):519-27.
Korelitz BI, Sommers SC. "Responses to drug therapy in ulcerative colitis. Evaluation by rectal biopsy and histopathological changes." Am. J. Gastroenterol.. 1975;64(5):365-70. Abstract

To evaluate responses to medical therapy in ulcerative colitis, rectal biopsies of patients with active untreated disease, individuals with positive and negative sigmoidoscopic findings treated with salicylazosulfapyridine, prednisone and 6-mercaptopurine, alone and in combinations and noncolitis controls were compared histologically. Predominant histological observations were analyzed statistically. There were fewer crypt abscesses but more mucosal edema after all forms of therapy. Quantitative histopathological analysis failed to demonstrate that the response to one drug was significantly different from another.

Korelitz BI, Sommers SC. "Responses to drug therapy in ulcerative colitis. Evaluation by rectal biopsy and histopathological changes." Am. J. Gastroenterol.. 1975;64(5):365-70. Abstract

To evaluate responses to medical therapy in ulcerative colitis, rectal biopsies of patients with active untreated disease, individuals with positive and negative sigmoidoscopic findings treated with salicylazosulfapyridine, prednisone and 6-mercaptopurine, alone and in combinations and noncolitis controls were compared histologically. Predominant histological observations were analyzed statistically. There were fewer crypt abscesses but more mucosal edema after all forms of therapy. Quantitative histopathological analysis failed to demonstrate that the response to one drug was significantly different from another.

Brezina R, Schramek S, Kazár J. "Selection of chlortetracycline-resistant strain of Coxiella burnetii." Acta Virol.. 1975;19(6):496.
Sinelnikova EM, Dvoretskova TV, Kagan ZS. "[Intermediate plateaux in kinetics of the reaction catalyzed by biodegradative L-threonine dehydratase from Escherichia coli]." Biokhimiia. 1975;40(3):645-51. Abstract

It has been shown that for the reaction catalyzed by "biodegradative" L-threonine dehydratase from E. coli strains K-12 and 980 in 0.5 M phosphate-carbonate buffer, pH 8.4 and pH 9.5, the plots of initial reaction rate (v) versus the initial substrate concentration ([S]0 are characterized by several inflection points, i. e. an intermediate plateau. The plot of v versus the allosteric activator (AMP) concentration have very complicated shapes: there are several inflection points, and also the maximum at L-threonine concentration equal to 3-10(2) and 5-10(-2) M. High AMP concentrations inhibit the enzyme at high substrate concentrations. The reduced glutathion dose not influence the enzyme and does not alter the activating effect of AMP. On the basis of the data obtained it is proposed that the substrate and AMP shift the equilibrium between multiple oligomeric enzyme forms differing in catalytic activity and kinetic manifestations of allosteric interactions between the active and allosteric AMP-binding sites towards polymerization. Thus, the functioning the enzyme under study is discussed in the frames of the model of dissociating regulatory enzymes with multiple intermediate oligomeric forms.

Siegel S. "Evidence from rats that morphine tolerance is a learned response." J Comp Physiol Psychol. 1975;89(5):498-506. Abstract

It is proposed that the direct analgesic effect of morphine becomes attenuated over the course of successive administrations of the narcotic by a conditioned, compensatory, hyperalgesic response elicited by the administration procedure, the net result being analgesic tolerance. Using the "hot plate" analgesia assessment situation with rats, this conditioning view of tolerance is supported by several findings: (a) It is necessary to have reliable environmental cues predicting the systemic effects of morphine if tolerance is to be observed, (b) a hyperalgesic conditioned response may be observed in morphine-tolerant subjects when drug administration cues are followed by a placebo, and (c) merely by repeatedly presenting environmental cues previously associated with morphine (but now presented with a placebo), morphine tolerance can be extinguished.

Wrightstone RN, Smith LL, Wilson JB, Vella F, Huisman TH. "Some physicochemical properties of hemoglobin-manitoba (alpha2 102Ser replaced by Arg (G9) beta2)." Biochim. Biophys. Acta. 1975;412(2):283-7. Abstract

Hb-Manitoba was discovered in 1970 [1] in a Canadian family of British origin. Recently we observed the same variant in a second family, and found that the oxy-derivative of Hb-Manitoba is slightly unstable at 65 degrees C, dissociates less readily at alkaline pH than does Hb-A, and forms asymmetric hybrids with other hemoglobins which are readily detectable by electrophoresis.

Sanchez G, Alderete JF. "The effect of host adrenalectomy on the physiology of Trypanosoma rhodesiense." Comp Biochem Physiol A Comp Physiol. 1975;52(4):623-6.
Höltje JV, Mirelman D, Sharon N, Schwarz U. "Novel type of murein transglycosylase in Escherichia coli." J. Bacteriol.. 1975;124(3):1067-76. Abstract

The purification and properties of a novel type of murein transglycosylase from Escherichia coli are described. The purified enzyme appears as a single band on sodium dodecyl sulfate-polyacrylamide gels and has an apparent molecular weight of approximately 65,000 as estimated by gel filtration and gel electrophoresis. It degrades pure murein sacculi from E. coli almost completely into low-molecular-weight products. The two prominent muropeptide fragments in the digest are the disaccharide-tripeptide N-acetylglucosamine-N-acetylmuramic acid-L-alanine-D-iso-glutamic acid-meso-diaminopimelic acid and the corresponding disaccharide-tetrapeptide N-acetylglucosamine-N-acetylmuramic acid-L-alanine-D-iso-glutamic acid-meso-diaminopimelic acid-D-alanine. The unique feature of these compounds is that the disaccharide has no reducing end group and that the muramic acid residue possesses an internal 1 leads to 6 anhydro linkage. The new lytic enzyme is designated as a murein: murein transglycosylase. Its possible role in the rearrangement of murein during cell growth and division is discussed.

Smith RC, Stricker CM. "Nucleosides and nucleotides of the cold acid-soluble portion of the blood of steers." J. Anim. Sci.. 1975;41(6):1674-8.
Mitchell B, Haigis E, Steinmann B, Gitzelmann R. "Reversal of UDP-galactose 4-epimerase deficiency of human leukocytes in culture." Proc. Natl. Acad. Sci. U.S.A.. 1975;72(12):5026-30. Abstract

Stimulation with phytohemagglutinin of the leukocytes from six of the seven known individuals with UDP-galactose 4-epimerase (= UDP-glucose 4-epimerase; EC 5.1.3.2) deficiency consistently resulted in the appearance of epimerase activity in the cultured cells. A long-term lymphoblast culture derived from one proband also contained an active epimerase enzyme. A comparison of the properties of this enzyme with those of epimerase produced by control lymphoblast lines revealed comparable Km values for UDP-galactose and NAD and identical behavior on polyacrylamide electrophoresis. However, a difference in the NAD requirement for heat stability at 40 degree provided some evidence for a structural defect in this enzyme. Possible explanations for the appearance of UDP-galactose 4-epimerase activity in stimulated lymphocytes include an increased rate of synthesis of a mutant enzyme and a derepression of an epimerase locus during lymphocyte transformation.

Schwabbauer ML. "Use of the latent image technique to develop and evaluate problem-solving skills." Am J Med Technol. 1975;41(12):457-62. Abstract

This project involved designing, developing and evaluating a simulation module, utilizing the latent image technique. The general topic chosen for this simulation was the laboratory characterization of anemias. Target learner populations included medical technology students, physician assistant students, and pathology residents. Members of all three groups participated in the evaluation of the module and responded to its use in varied settings.

Schwabbauer ML. "Use of the latent image technique to develop and evaluate problem-solving skills." Am J Med Technol. 1975;41(12):457-62. Abstract

This project involved designing, developing and evaluating a simulation module, utilizing the latent image technique. The general topic chosen for this simulation was the laboratory characterization of anemias. Target learner populations included medical technology students, physician assistant students, and pathology residents. Members of all three groups participated in the evaluation of the module and responded to its use in varied settings.

Anderson TR, Slotkin TA. "Maturation of the adrenal medulla--IV. Effects of morphine." Biochem. Pharmacol.. 1975;24(16):1469-74.
Anderson TR, Slotkin TA. "Maturation of the adrenal medulla--IV. Effects of morphine." Biochem. Pharmacol.. 1975;24(16):1469-74.
Gluecksohn-Waelsch S, Schiffman MB. "Glutamine synthetase in newborn mice homozygous for lethal albino alleles." Dev. Biol.. 1975;45(2):369-71.
Di Ferrante N, Leachman RD, Angelini P, Donnelly PV, Francis G, Almazan A, Segni G, Franzblau C, Jordan RE. "Ehlers-Danlos type V (X-linked form): a lysyl oxidase deficiency." Birth Defects Orig. Artic. Ser.. 1975;11(6):31-7.
Siddiqui KA, Banerjee AK. "Fructose 1,6-bisphosphate aldolase activity of Rhizobium species." Folia Microbiol. (Praha). 1975;20(5):412-7. Abstract

FDP aldolase was found to be present in the cell-free extracts of Rhizobium leguminosarum, Rhizobium phaseoli, Rhizobium trifolii, Rhizobium meliloti, Rhizobium lupini, Rhizobium japonicum and Rhizobium species from Arachis hypogaea and Sesbania cannabina. The enzyme in 3 representative species has optimal activity at pH 8.4 in 0.2M veronal buffer. The enzyme activity was completely lost by treatment at 60 degrees C for 15 min. The Km values were in the range from 2.38 to 4.55 X 10(-6)M FDP. Metal chelating agents inhibited enzyme activity, but monovalent or bivalent metal ions failed to stimulate the activity. Bivalent metal ions in general were rather inhibitory.

S.K.A D, S.O K, M A. "Protozoa and the decline of Rhizobiurn populations added to soil.". 1975. Abstract

A fall in Rhizobium abundance occurred in nonsterile soil inoculated with large numbers of the root-nodule bacteria but many of the rhizobia still survirved. No such decline was evident in sterile soil. Protozoa feeding on these bacteria were isolated from soil and other environments. As the abundance of Rhizobium meliloti and a cowpea Rhizobium strain in soil decreased, the protozoan density increased. The inability of the predators to eliminate their prey,from soil was not the result of the presence of organisms feeding on the protozoa because many rhizobia survived in sterile soil inoculated with the prey and cultures of individual protozoa nor was it the result of the rapid multiplication of the bacteria to replace those consumed because survivors were still numerous in essentially organic matter free soil in which the hactena did not grow appreciably. The lack of elimination also was not associated with a protective effect of soil particles because survivors were still abundant in solutions inocuiated with protozoa and bacteria.It is suggested that the size of the prey population diminishes until a density is attained at which the energy used by the predator in hunting for the survivors equals that obtained from the feeding.

SAMSON PROFMEMEJULIUS. "Meme J. S., Oduori, M.L., Gripenberg, Fanconi's Aplastic Anaemia, case report and review of the Literature. E. Afr. Med. J. 54: 44, 1975.". In: E. Afr. Med. J. 54: 44, 1975. au-ibar; 1975. Abstract
No abstract available.
SAMUEL PROFKIBICHO. ""Some features of African Religion of lasting value," Thought and Practice, the journal of the Philosophical Association of Kenya.". In: Proceedings of 3rd Int. Conf. On bearing capacity of roads and airfields PP 743-756, Trondeihm, Norway. Longhorn; 1975. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
SAMUEL PROFKIBICHO. ""The church and the question of violence in the African Liberation struggle, " Hekima, Journal of the Humanities and Social Sciences.". In: Proceedings of 3rd Int. Conf. On bearing capacity of roads and airfields PP 743-756, Trondeihm, Norway. Longhorn; 1975. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
SAMUEL PROFKIBICHO. ""Why teach or study African Traditional Religion in Modern Africa?" Orientation, the Journal of Religious studies in Kenya, Vol. I, No.1 pp. 1 - 12.". In: Proceedings of 3rd Int. Conf. On bearing capacity of roads and airfields PP 743-756, Trondeihm, Norway. Longhorn; 1975. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
1974
Page MM, Alberti KG, Greenwood R, Gumaa KA, Hockaday TD, Lowy C, Nabarro JD, Pyke DA, Sönksen PH, Watkins PJ, West TE. "Treatment of diabetic coma with continuous low-dose infusion of insulin." British Medical Journal. 1974;2:687-690. Abstract

Thirty-eight patients in diabetic coma from four different centres were treated with a continuous low-dose intravenous infusion of insulin at an average dose of 7.2 IU/hr. All patients recovered rapidly except for one profoundly shocked patient who died. The mean fall in plasma glucose was 58% four hours after the start of insulin. Blood ketone bodies and plasma free fatty acids showed a similar response. There was no significant difference in plasma glucose response according to severity of acidosis or previous treatment with insulin. Hypokalaemia was uncommon. In the treatment of diabetic coma this technique has proved simple, safe, and effective.

1973
1972
Bhui KS, Fiorillo A, Stein D, Okasha T, Ndetei D, Lam L, Chaturvedi S, Maj M. "Improving education, policy and research in mental health worldwide: the role of the WPA Collaborating Centres." Immunology. 1972.Website
SAMUEL PROFKIBICHO. ""African Traditional Religion & Christanity".". In: In A New Look at Christianity In Africa (WSCF book, vol. II, No.2 1972, Serial No. 5, Geneva) pp. 1-12. Longhorn; 1972. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
Thomasson B, Sutinen S. "Chronic primary intussusception in an infant." Journal of pediatric surgery. 1972;7:299-301. AbstractWebsite
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S PROFKIGONDUCHRISTINE. "Contraceptives, clients and the medical profession. Kenya Nurs J. 1972 Jun;1(1):48-50.". In: Kenya Nurs J. 1972 Jun;1(1):48-50. uon press; 1972. Abstract

PIP: Masturbatory semen specimen from 49 fertile Black African males in Kenya whose wives were pregnant was obtained after at least 3 days of abstinence for the analysis of parameters which included volume motility, vitality, sperm concentration, pH, fructose and acid phosphatase levels. About 1/2 the spermatozoa was actively progressive in motility, while 40% was nonmotile. Vitality in the 1st hour revealed that 81.4% of the sperm was alive. About 90% of the semen specimens had more than 40% idea forms of spermatozoa. Spermatozoal abnormalities were a frequent feature. There was no correlation between age and the testicular volume, but seminal fluid volume and sperm density tended to decrease with age. Serum levels of Follicle Stimulating Hormone, Luteinizing Hormone, Prolactin and Testosterone were determined in the subjects' sera, enabling the establishment of reference values for these parameters in African Kenyan males.

SHAWKY PROFROSTOMRAOUF, SHAWKY PROFROSTOMRAOUF. "Rostom R. S, 1972: The use of Proper Weight Numbers in the Analytical determination of the Elements of Relative Orientation, Scientific Bulletin No. 36, Faculty of Engineering, Cairo University.". In: A Keynote Address to the AFRICAGIS Conference and Exhibition, Nairobi, Kenya. The Icfai University Journal of Architecture, Vol. II No.1, February 2010; 1972.
SAMUEL PROFKIBICHO. ""The Kikuyu Coception of God, its continuity into the Christian Era and the Wuestions it raises for the Christian Idea of Revelation: Vanderbilt University, Nashville.". In: Proceedings of 3rd Int. Conf. On bearing capacity of roads and airfields PP 743-756, Trondeihm, Norway. Longhorn; 1972. Abstract
 Journal of Civil Engineering, Jomo Kenyatta University of Agriculture and Technology Vol.7 PP
1971
Sosula L, Glow PH. "Increase in number of synapses in the inner plexiform layer of light deprived rat retinae: {Quantitative} electron microscopy." The Journal of Comparative Neurology. 1971;141:427-451. AbstractWebsite

One eye in each of five adult Wistar hooded rats was covered with opaque contact occluders for three or nine months. The rat retinae were studied with light and electron microscopy. No changes in retinal thickness or in gross structure were seen. However, quantitative differences in synaptic organisation were found.(1) First comparison. A montage of a normal retina was compared with a similar montage of a three month lighted-deprived retina. Taking equal areas of inner plexiform layer, the number of amacrine (conventional) synapses in the light-deprived montage was larger by a factor of about 2.4 relative to the normal one. No significant difference in the number of bipolar (ribbon) synapses was found.(2) Second comparison. Samples were compared from five normal and five light-deprived retinae. The light-deprived retinae showed a significantly larger number of amacrine synapses compared with the normal mean (p{\textless}0.02).It was not possible to determine if the changes in synaptic number are related to changes in vesicle dimensions reported herein.The increased number of conventional synapses seems evidence that central nervous tissue is capable of forming new synapses without changing the organisation of neural processes.

1970
Sulway MJ, Malins JM. "Acetone in diabetic ketoacidosis." Lancet. 1970;2:736-740. Abstract
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MEHRA KL, Singh CB, KOHLI KS. "Phenotypic diversity and breeding of forage cowpea."; 1970.
SIALO MRWEEREWASHINGTONBOOKER. "Ayugi O.; Weere, W.B.S; Mwairo, J.M;Aerial Triangulation and Block Adjustment of Migori block with Independent Models.". In: published by Institute of Surveyors of Kenya. ARCHWAY Technology Management Ltd; 1970. Abstract
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SAMSON PROFMEMEJULIUS. "Meme J. S. Carcinoma of Thyroid Nairobi Journal of Medince 1: 23, 1970.". In: Nairobi Journal of Medince 1: 23, 1970. au-ibar; 1970. Abstract
No abstract available.
SIALO MRWEEREWASHINGTONBOOKER. "Obel, J D; Weere, WBS: Application of Geo-Information System for Conflict Resolution of disputed Boundary between Osilalei and Eselenkei Ranches;.". In: presented during the Kajiado District Heads. ARCHWAY Technology Management Ltd; 1970. Abstract
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SIALO MRWEEREWASHINGTONBOOKER. "Obel, J D; Weere, WBS:Establishment of Geo- Information System to phases one and two boundary disputes; problem solving approach of Ewuaso Kedong Group Ranch Project.". In: presented during the Kajiado District Heads. ARCHWAY Technology Management Ltd; 1970. Abstract
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SIALO MRWEEREWASHINGTONBOOKER. "Prof Odingo, R S & Weere, WBS; Proposal on establishment of an Integrated Geographic and Environmental Information Systems .". In: presented during International donor Conferen. ARCHWAY Technology Management Ltd; 1970. Abstract
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SIALO MRWEEREWASHINGTONBOOKER. "Weere, WBS: Draft Project Proposal on planning and Facility Management of research activities within Africa Medical Research Foundation (AMREF) setup.". In: published by Institute of Surveyors of Kenya. ARCHWAY Technology Management Ltd; 1970. Abstract
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SIALO MRWEEREWASHINGTONBOOKER. "Weere,WBS; Obel, J D:Integration of Technology and Business towards enhancement of Micro and Small Enterprises in Kenya.". In: presented during International donor Conferen. ARCHWAY Technology Management Ltd; 1970. Abstract
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202

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