Publications

Found 44 results

Sort by: Author Title Type [ Year  (Desc)]
2018
Ooko JO, J.O. O, A.O. Y, P.M. G. "Use of accelerated tests to estimate corrosion rates of roofing sheets." International Journal of Sciences. 2018;37(3):1-8.publication_juspher_onyatta_yusuf_guto.pdf
2017
Birgen J, Yusuf AO, Wafula G, Onyatta JO. "Assessment of sulphur dioxide levels in selected sites in Athi River, Kenya." International Journal of Trend in Scientific Research and Development. 2017;1(5):416-422.scan_trend.pdf
2016
2015
V. S, J. K, B. O, A. Y, M. K. "In-vitro anthelmintic activity of vernonia amygdalina Del. (asteraceae) roots using adult Haemonchus contortus worms." International Journal of Pharmacological Research. 2015;5(1):1-7.vernonia_amygdalina.pdf
2014
Yusuf A, Gitu P, Bhatt B, Njogu M, Salim A, Orata D. "1-Tetralinyl as carboxamide protecting group for asparagines and application to N-alpha-t-butyloxycarbonyl (Boc) solid-phase peptide synthesis of oxytocin." chemistry and materials research. 2014;6(2):1-11.
Muiva L, Macharia B, Akala H, Derese S, Omosa LK, Yusuf A, Kamau E, Koch A, Heidenreich M, Yenesew A. "6a-Hydroxy-α-toxicarol and (+)-Tephrodin with antiplasmodial activities from Tephrosia species." Phytochemistry Letters. 2014;10:179-183.scan0062.pdf
Yusuf A, Gitu P, Bhatt BM, Njogu M, Salim A, Orata D. "Solid-Phase Peptide Synthesis of Arginine-vasopressin With Amide Side chain of Asparagine Protected With 1-Tetralinyl Group." Journal of Chemistry & Materials Research. 2014;6(4):60-65.
Yusuf AO, Gitu PM, Bhatt BM, Njogu M, Salim A, Orata D. "Solid-Phase Peptide Synthesis of Arginine-vasopressin With Amide Side chain of Asparagine Protected With 1-Tetralinyl Group." Journal of Chemistry & Materials Research. 2014;6(4):60-65.cmr_spps_arg_vaso.pdf
Orata D, Yusuf AO, Nineza C, Mukabi M, D. M. "Surface Modified Electrode Used In the Electro-Analysis of N- Acetyl P-Aminophenol- A Pharmaceutical Drug ." Journal of Applied Chemistry. 2014;7(5):90-99.iosr_7_5_2_2014_acetyl.pdf
Orata D, Yusuf AO, Nineza C, Mbui D, Mukabi M. "Surface modified electrodes used in cyclic voltammetric profiling of quinine, as antimalarial drug." Journal of Applied Chemistry. 2014;7(5):81-89.iosr_7_5_2_2014_quinine.pdf
Orata D, Yusuf A, Nineza C, Mbui D, Mukabi M. "Surface modified electrodes used in cyclic voltammetric profiling of quinine, as antimalarial drug”." IOSR Applied Chemistry. 2014;7(5, ver II):81-89.scan0001.pdf
2011
2010
Mbugua P, Salim A, Onditi A, Yusuf A. "Determination of Micronutrients and micronutrients in Soil Samples from Around Lake Ol-Bolossat." Int. J. Biol. Sci.. 2010;2(8):140-148.scan0016.pdf
DM K, A S, A O, A Y. "Environmental effects of selected chemical and physical geothermometers at Olkaria Geothrmal power plant." Journal of Sustainable Development. 2010;3(6):14-25. Abstractscan0015.pdfWebsite

21) S. Derese, A. Yenesew, J.O. Midiwo, Heydenreich and M.G. Peter. (). ..

2007
Mbugua MN, Yusuf AO, Bhatt BM, P.M. G. "CONVERSION OF VERNONIA GALAMENSIS OIL TO PYRIDINYLVERNOLAMIDES AND THEIR ANTIMICROBIAL ACTIVITIES ." Bulletin of the Chemical Society of Ethiopia. 2007;21(1):103-110.bcse_21_1_vernonia_galamensis_2007.pdf
2006
2005
SA O, PF M, GJ S, J M, S K, GA O, HD. S. "Plasmodium falciparum: evaluation of a quantitative nucleic acid sequence-based amplification assay to predict the outcome of sulfadoxine-pyrimethamine treatment of uncomplicated malaria.". 2005. AbstractFull text link

A quantitative nucleic acid sequence-based amplification (QT-NASBA) assay was employed to predict retrospectively the outcome of sulfadoxine-pyrimethamine (SP) treatment of uncomplicated malaria in children aged <6 years in an endemic region. Blood samples were collected at initial diagnosis and during follow-up. Mutation-specific nested PCR methods to analyse DHFR (Arg-59) and DHPS (Glu-540) mutations that are associated with SP drug resistance were applied. Parasite genotyping was performed to distinguish between re-infection and recrudescence. Eighty-six patients were recruited of which 66 were available for follow-up. Nine children were classified as early treatment failure, 13 cases were classified as late clinical failure, 32 as late parasitological failure, and only 12 children had an adequate clinical and parasitological response. DHFR and DHPS mutations conferring SP resistance were abundant in the Plasmodium population. Blood samples obtained 7 days after treatment were used to predict retrospectively the outcome of SP treatment. QT-NASBA was able to give a correct prediction of treatment outcome in 85.7% of the cases. Positive predictive value (PPV) of QT-NASBA case was 95% (95% confidence interval = 88.3-100) and negative predictive value (NPV) was 63% (95% CI = 39.5-86.5). In contrast, microscopy correctly predicted outcome in only 37.5% of the cases. PPV of microscopy was 100% (95% CI = 73.9-100) and the NPV was 25.5% (95% CI = 13.0-38.0). The analysis of a day 7 blood sample with QT-NASBA allows for the prediction of late clinical or parasitological treatment failure in the majority of the cases analysed in the present study.

2004
Yusuf A. Organic Chemistry 2 (SCH 202). Nairobi: University of Nairobi Press; 2004.scan0023.pdf
2002
2001
1998
Gitu P, Yusuf A, Ogutu V. "Application of tetralinyl group in solid-phase peptide synthesis." Int. J. BioChemiPhysics. 1998;6,7(1,2):7-10.scan0055.pdf
Gitu PM, Yusuf A, Bhatt BM. "Application of tetralinyls as carboxamide protecting groups in peptide synthesis." Bulletin of the Chemical Society of Ethiopia. 1998;12(1):35-43.bcse_12_1_1998.pdf
YUSUF DROKEYOAMIR. "Solid-phase peptide syntheses of oxytocin, oxytocin analogs and interferon short chain with the amide side-chain functionality of asparagine protected with 1-tetralinyl group.". In: Doctor of Philosophy in Chemistry. Journal of the Kenya Chemical Society; 1998. Abstract
1-Tetralone was converted to 1-aminotetralin. This amine was then used to protect the carboxamide side-chain of asparagine. Syntheses of oxytocin and its derivatives were then done via Boc-solid-phase peptide synthesis using this protected asparagine. After syntheses of the nonapeptide resins, cleavage and eventual cyclization of the hormones was done using trifluoromethane sulphonic acid at 40 degrees Celcius for two hours.
1993
Bhatt B, Gitu P, Yusuf A. "Synthesis of 1-aminotetralin and its derivatives by reductive amination of their corresponding 1-tetralones"." Int. J. BioChemiPhysics. 1993;2(1,2):55-77.
YUSUF DROKEYOAMIR. "Synthesis of 1-aminotetralin and its derivatives by reductive amination of their corresponding 1-tetralones.". In: Int. J. of BioChemiPhysics. Journal of BiochemiPhysics; 1993. Abstract
Tetralones were converted to their corresponding N-formyl derivatives using ammonia and formic acid at 170-180 degrees Celsius. These were then hydrolyzed to the corresponding amines using acid and base. In all cases base hydrolysis gave better yields as compared to acid hydrolysis.
1989

UoN Websites Search