The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense.

Citation:
Yenesew A. "The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense." Arkivoc 21-27. . 2007;ix:21-27.

Abstract:

Phytochemical re-examination of the aerial exudates of Polygonum senegalense forma senegalense has resulted in the isolation and charachterization of a novel homoisoflavonoid, 5,7-dihydroxy-3-(hydroxy-phenyl-methyl)-6-methoxy-chroman-4-one (trivial name: polygohomoisoflavanone). The structure was determined on the basis of spectroscopic evidence. The new compound along with other components of the aerial exudate showed good antiplasmodial activities towards chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum.

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