Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline

Citation:
Yenesew A. "Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline." Journal of Natural Products. 2002;65:566-569.

Abstract:

Extracts from Schizozygia coffaeoides showed antimicrobial activity against fungal and bacterial species. Alkaloids isolated using bioassay-guided fractionation were isoschizogaline, schizogynine, and a new indoline alkaloid, 7,8-dehydro-19beta-hydroxyschizozygine, shown to be the most active antifungal compound. The structure of isoschizagaline, the only active antibacterial, is revised on the basis of NMR analysis.

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